JasonChun HangWongMD

PubMed

• Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia.
  Dail, M.,Wong, J.,Lawrence, J.,O'Connor, D.,Nakitandwe, J.,Chen, S. C.,Xu, J.,Lee, L. B.,Akagi, K.,Li, Q.,Aster, J. C.,Pear, W. S.,Downing, J. R.,Sampath, D.,Shannon, K.> ;Nature. 2014 Jul 22
• A phase I, randomized, open-label study of the multiple-dose pharmacokinetics of vemurafenib in patients with BRAF (V600E) mutation-positive metastatic melanoma.
  Grippo, J. F.,Zhang, W.,Heinzmann, D.,Yang, K. H.,Wong, J.,Joe, A. K.,Munster, P.,Sarapa, N.,Daud, A.> ;Cancer Chemother. Pharmacol.. 2013 Nov 02
• 21 citations
  Evaluation of cartilage degeneration in a rat model of rotator cuff tear arthropathy
  Erik J. Kramer, Blake M. Bodendorfer, Dominique Laron, Jason Wong, Hubert T. Kim, Xuhui Liu, Brian T. Feeley> ;Journal of Shoulder and Elbow Surgery. 2013 Dec 1
• Structural biasing elements for in-cell histone deacetylase paralog selectivity.
  Wong, J.C., Hong, R., Schreiber, S.L.> ;J Am Chem Soc. 2003 May 14
• Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation.
  Haggarty, S.J., Koeller, K.M., Wong, J.C., Grozinger, C.M., Schreiber, S.L.> ;Proc Natl Acad Sci U S A. 2003 Apr 15
• Application of p21 and klf2 reporter gene assays to identify selective histone deacetylase inhibitors for cancer therapy.
  Wong, J. C., Guo, L., Peng, Z., Zhang, W., Zhang, N., Lai, W., Zhang, Z., Zhang, C., Zhang, X., Song, S., Pan, D., Xie, C., Li, J., Ning, Z., Lu, X., He, Y., Chen, L.> ;Bioorg Med Chem Lett. 2011 Jan 1
• Cerebral grey, white matter and csf in never-medicated, first-episode schizophrenia.
  Chua, S. E., Cheung, C., Cheung, V., Tsang, J. T., Chen, E. Y., Wong, J. C., Cheung, J. P., Yip, L., Tai, K. S., Suckling, J., McAlonan, G. M.> ;Schizophr Res. 2007 Jan
• Mapping chemical space using molecular descriptors and chemical genetics: deacetylase inhibitors.
  Haggarty, S. J., Clemons, P. A., Wong, J. C., Schreiber, S. L.> ;Comb Chem High Throughput Screen. 2004 Nov
• Modular synthesis and preliminary biological evaluation of stereochemically diverse 1,3-dioxanes.
  Wong, J. C., Sternson, S. M., Louca, J. B., Hong, R., Schreiber, S. L.> ;Chem Biol. 2004 Sep
• Chemical genetic modifier screens: small molecule trichostatin suppressors as probes of intracellular histone and tubulin acetylation.
  Koeller, K. M., Haggarty, S. J., Perkins, B. D., Leykin, I., Wong, J. C., Kao, M. C., Schreiber, S. L.> ;Chem Biol. 2003 May
• Multidimensional chemical genetic analysis of diversity-oriented synthesis-derived deacetylase inhibitors using cell-based assays.
  Haggarty, S. J., Koeller, K. M., Wong, J. C., Butcher, R. A., Schreiber, S. L.> ;Chem Biol. 2003 May
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