JeffreyM.HarrisMDPhD

PubMed

• 21 citations
  Molecular architecture determines brain delivery of a transferrin receptor-targeted lysosomal enzyme.
  Annie Arguello, Cathal S Mahon, Meredith E K Calvert, Darren Chan, Jason C Dugas, Michelle E Pizzo, Elliot R Thomsen, Roni Chau, Lorna A Damo, Joseph Duque, Meng Fang,...> ;The Journal of Experimental Medicine. 2022 Mar 7
• 10 citations
  Iduronate-2-sulfatase transport vehicle rescues behavioral and skeletal phenotypes in a mouse model of Hunter syndrome.
  Annie Arguello, René Meisner, Elliot R. Thomsen, Hoang N. Nguyen, Ritesh Ravi, Jeffrey Simms, Iris Lo, Jessica Speckart, Julia Holtzman, Thomas M. Gill, Darren Chan, Y...> ;JCI Insight. 2021 Oct 8
• 2 citations
  A phase 1, randomized study to evaluate safety, tolerability, and pharmacokinetics of GDC-3280, a potential novel anti-fibrotic small molecule, in healthy subjects.
  Dorothy Cheung, Alice Fong, Han Ting Ding, Christopher R. Cabanski, Jianshuang Wang, Yuan Chen, Jim Bush, Jeffrey M. Harris, Lin Pan> ;Pulmonary Pharmacology & Therapeutics. 2021 Jun 21
• 6 citations
  High-Throughput Liquid Chromatography-Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II.
  Junhua Wang, Akhil Bhalla, Ullman Julie, Meng Fang, Ritesh Ravi, Annie Arguello, Elliot R. Thomsen, Buyankhishig Tsogtbaatar, Jing L. Guo, Lukas L. Skuja, Jason C. Dug...> ;International Journal of Molecular Sciences. 2020 Jul 30
• 11 citations
  Characterization of Fluid Biomarkers Reveals Lysosome Dysfunction and Neurodegeneration in Neuronopathic MPS II Patients.
  Akhil Bhalla, Ritesh Ravi, Meng Fang, Annie Arguello, Sonnet S. Davis, Chi-Lu Chiu, Jessica R. Blumenfeld, Hoang N. Nguyen, Timothy K. Earr, Junhua Wang, Giuseppe Asta...> ;International Journal of Molecular Sciences. 2020 Jul 22
• Elevated IgE M1 prime transcripts in nasal tissues in patients with nasal polyps and asthma.
  Scheerens, H.,Smith, A.,Li, O.,Honigberg, L.,Harris, J. M.,Holtappels, G.,Bachert, C.> ;J. Allergy Clin. Immunol.. 2018 Oct 26
• A randomized trial of quilizumab in adults with refractory chronic spontaneous urticaria.
  Harris, J. M., Harris, J. M., Cabanski, C. R., Cabanski, C. R., Scheerens, H., Scheerens, H., Samineni, D., Samineni, D., Bradley, M. S., Bradley, M. S., Cochran, C., ...> ;The Journal of allergy and clinical immunology. 2016 Aug 28
• 59 citations
  A randomized trial of the efficacy and safety of quilizumab in adults with inadequately controlled allergic asthma
  Jeffrey M. Harris, Romeo Maciuca, Mary S. Bradley, Christopher R. Cabanski, Heleen Scheerens, Jeremy J. Lim, Fang Cai, Mona Kishnani, X. Charlene Liao, Divya Samineni,...> ;Respiratory Research. 2016 Mar 18
• Disconnect between sputum neutrophils and other measures of airway inflammation in asthma.
  Arron, J. R.,Choy, D. F.,Laviolette, M.,Kelsen, S. G.,Hatab, A.,Leigh, R.,Thomson, N. C.,Bleecker, E. R.,Olivenstein, R.,Avila, P. C.,Jarjour, N. N.,Castro, M.,Gauvrea...> ;Eur. Respir. J.. 2013 Nov 02
• Exploring the effects of omalizumab in allergic asthma.
  Hanania, N. A.,Wenzel, S.,Rosén, K.,Hsieh, H. J.,Mosesova, S.,Choy, D. F.,Lal, P.,Arron, J. R.,Harris, J. M.,Busse, W.> ;Am. J. Respir. Crit. Care Med.. 2013 Apr 15
• 10 citations
  Development of the Asthma Control Composite outcome measure to predict omalizumab response.
  Jeffrey M. Harris, Dennis A. Wong, Amy V. Kapp> ;Annals of Allergy, Asthma & Immunology. 2011 Sep 1
• Lebrikizumab Treatment in Adults with Asthma.
  Corren, J., Lemanske, R.F., Hanania, N.A., Korenblat, P.E., Parsey, M.V., Arron, J.R., Harris, J.M., Scheerens, H., Wu, L.C., Su, Z., Mosesova, S., Eisner, M.D., Bohen...> ;N Engl J Med. 2011 Sep 22
• Recent thymic emigrants and subsets of naive and memory T cells in the circulation of patients with head and neck cancer.
  Kuss, I., Schaefer, C., Godfrey, T.E., Ferris, R.L., Harris, J.M., Gooding, W., Whiteside, T.L.> ;Clin Immunol. 2005 Jul
• 60 citations
  Multiparameter evaluation of human thymic function: interpretations and caveats.
  Jeffrey M. Harris, Mette D. Hazenberg, Jean-François Poulin, Dana Higuera-Alhino, D K Schmidt, Michael B. Gotway, Joseph M. McCune> ;Clinical Immunology. 2005 May 1
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Journal Articles

• Safety and Efficacy of MHAA4549A, a Broadly Neutralizing Anti-Influenza A Monoclonal Antibody: A Randomized, Double Blind, Placebo Controlled Clinical Trial in a Human...  
  McBride, JM, Lim, JJ, Burgess, T, Deng, R, Derby, M, Maia, M, Horn, P, Siddiqui, O, Sheinson, D, Chen, H, Newton,, EM, Fillos, D, Nazzal, D, Rosenberger, CM, Ohlson, ..., Antimicrob Agents Chemother, 1/1/2017
• Increased IgE+ B cells in sputum, but not blood, bone marrow or tonsils, after inhaled allergen c challenge in asthmatic subjects  
  Oliveria, JP, Salter, BS, MacLean, J, Kotwal, S, Smith, A, Harris, JM, Scheerens, H, Sehmi, R, GM Gauvreau, Am J Respir Crit Care Med, 1/1/2017
• Increased autophagy related 5 gene expression is associated with collagen expression in the airways of refractory asthmatics  
  Poon, AH, Choy, DF, Chouiali, F, Ramakrishnan, RK, Mahboub, B, Audusseau, S, Mogas, A, Harris, JM, Arron, JA, Laprise, C, Hamid Q, Frontiers in Immunology, 1/1/2017
• Current Status of Companion and Complementary Diagnostics: Strategic Considerations for Development and Launch  
  Scheerens, H, Malong, A, Bassett, K, Boyd, Z, Gupta, V, Harris, J, Mesick, C, Simnett, S, Stevens, H, Gilbert, H, Risser, P, Kalamegham, R, Jordan, J, Engel, J, Chen, ..., Clin Transl Sci, 1/1/2017
• Asthma Susceptibility IL33 SNP rs4742165 is an eQTL for Asthmatic Serum sST2  
  Li, O, Jia, G, Dressen, A, Yaspan, B, Beasley, R, Fingleton, J, Holweg, CTJ, Matthews, JG, Harris, JM, Scheerens, H, Arron, JR, Choy, DF, Staton, TL, American Thoracic Society International Conference, 1/16/2016
• Predictive Performance of Non-Invasive Type 2 Biomarkers for Asthmatic Sputum Eosinophils in BOBCAT and U-BIOPRED Studies  
  Choy, DF, Cai, F, Knowles, RG, Djukanovic, R, Shaw, D, Sterk, PJ, Chung, F, Dahlen, S-E, Harris, JM, Matthews, JG, Arron, JR, Scheerens, H, Holweg, CTJ, American Thoracic Society International Conference, 1/16/2016
• A randomized trial of quilizumab in adults with refractory chronic spontaneous urticarial  
  Harris, JM, Cabanski C, Scheerens, H, Samieni, D, Bradley, MS, Cochran, C, Staubach, P, Metz, M, Sussman, G, Maurer, M, J Allergy Clin Immunol, 1/1/2016
• A randomized trial of the efficacy and safety of quilizumab in adults inadequately controlled allergic asthma  
  Harris, JM, Maciuca R, Bradley, S, Cabanski C, Scheerens, H, Lim, J, Cai, F, Kishnani, M, Liao, XC, Samieni, D, Zhu, R, Cochran C, Soong, W, Diaz, J, Perin P, Tsukayam..., Respir Res, 1/1/2016
• Efficacy and safety of quilizumab in adults with allergic asthma inadequately controlled on inhaled corticosteroids and a second controller (COSTA Study)  
  Harris, JM, Maciuca R, Bradley, S, Cabanski C, Scheerens, H, Lim, J, Cai, F, Kishnani, M, Liao, XC, Samieni, D, Zhu, R, Cochran C, Soong, W, Diaz, J, Perin P, Tsukayam..., American Thoracic Society International Conference, 1/19/2015
• The Airway Microbiome in Patients with Severe Asthma: Associations with Disease Features and Severity  
  Huang, YJ, Nariya, S, Harris, J, Lynch, SV, Choy, D, Arron, JR, Boushey, H, J Allergy Clin Immunol, 1/1/2015
• Targeting membrane-expressed IgE B cell receptor with an antibody against the M1 prime epitope: A novel method of reducing production of serum IgE  
  Gauvreau, GM, Harris, JM, Scheerens, H, Putnam, W, Zheng, Y, Wang, Y, Mosesova, S, Maciuca, R, Liao, XC, Wu, L, Matthews, JG, Boulet, L-P, Cockcroft, DW, Davis, B, Fit..., Science Translational Med, 1/1/2014
• The Airway Microbiome in Severe Asthma  
  Huang, YJ, Nariya, S, Lynch, SV, Harris, J, Choy, D, Arron, JR, Boushey, H, Ann Am Thorac Soc, 1/1/2014
• The effects of lebrikizumab in patients with mild asthma following whole lung allergen challenge  
  Scheerens, H, Arron, JR, Zheng, Y, Putnam, WS, Erickson, RW, Choy, DF, Harris, JM, Lee, J, Jarjour, NN, Matthews, JG, Clin and Exp Allergy, 1/1/2014
• Disconnect between sputum neutrophils and other measures of airway inflammation in asthma  
  Arron, JR, Choy, D, Laviolette, M, Kelsen, S, Hatab, A, Leigh, R, Thomson, N, Bleecker, E, Olivenstein, R, Avila, P, MD; Jarjour, N, Castro, M, Gauvreau, G, Good, J, K..., Eur Resp J, 1/1/2014
• EMerging BiomARKers in Inflammatory Bowel Disease (EMBARK) Study Identifies Fecal Calprotectin, Serum MMP9 and Serum IL-22 as a Novel Combination of Biomarkers for Cro...  
  Faubion Jr, WA, Fletcher, JG, O�Byrne, S, Feagan, B, de Villiers, WJS, Salzberg, B, Plevy, S, Proctor, DD, Valentine, JF, Higgins, PD, Harris, JM, Diehl, L, Wright, L,..., Am J Gastroenterology, 1/1/2013
• Exploring the Effects of Omalizumab in Allergic Asthma: An Analysis of Biomarkers in the EXTRA Study  
  Hanania, NA, Wenzel, S, Ros�n, K, Hsieh, H-J, Mosesova, S, Choy, DF, Lal, P, Arron, JR, Harris JM, Busse, W, Am J Respir Crit Care Med, 1/1/2013
• Periostin is a systemic biomarker of eosinophilic airway inflammation in asthma  
  Jia, G-Q, Erickson, RW, Choy, DF, Mosesova, S, Wu, LC, Solberg, OD, Shikotra, A, Carter, R, Audusseau, S, Hamid, Q, Bradding, P, Fahy, JV, Woodruff, PG, BOBCAT Study G..., J Allergy Clin Immunol, 1/1/2012
• Efficacy of lebrikizumab in asthma: determination of response using periostin  
  Corren, J, Lemanske, Jr., RF, Hanania, NA, Korenblat, PE, Parsey, MV, Arron, JR, Harris, JM, Scheerens, H, Su, Z, Mosesova, S, Eisner, M, Bohen, S, Matthews, JG, N Engl J Med, 1/1/2011
• Intermediate-affinity interleukin-2 receptor expression predicts CD56bright natural killer cell expansion after daclizumab treatment in the CHOICE study of patients wi...  
  Sheridan, JP, Zhang, Y, Riester, K, Tang, MT, Efros, L, Shi, J, Harris, JM, Vexler,V, Elkins, JS, Mult Scler J, 1/1/2011
• Development of the Asthma Control Composite Outcome Measure to Predict Omalizumab Response  
  Harris, JM, Wong, DA, Kapp, AV, Ann Allergy, 1/1/2011
• Periostin Is A Systemic Biomarker Of Eosinophilic Airway Inflammation In Asthma  
  Arron, JR, Jia, G-Q, Erickson, RW, Choy, DF, Mosesova, S, Solberg, OD, Shikotra, A, Carter, R, Audusseau, S, Hamid, Q, Bradding, P, Fahy, JV, Woodruff, P, Harris JM, Am J Respir Crit Care Med, 1/1/2011
• Predictive and Pharmacodynamic Biomarkers of Interleukin-13 Blockade: Effect of Lebrikizumab on Late Phase Asthmatic Response to Allergen Challenge  
  Scheerens, H, Arron, JR, Su, Z, Zheng, Y, Putnam, W, Erickson, RW, Choy, DF, Lee, JH, Harris, JM, Jarjour, N, Matthews, JG, J Allergy Clin Immunol, 1/1/2011
• Loss of T Cell Responses Following Long-term Cryopreservation  
  Owen, RE, Sinclair, E, Emu, B, Heitman, JW, Hirshkorn, DF, Epling, CL, Tan, QX, Custer, B, Harris, JM, Jacobson, MA, McCune, JM, Martin, JN, Hecht, FM, Deeks, SJ, Norr..., J Immunol Methods, 1/1/2007
• Detection of single clone deletions using array CGH: Identification of submicroscopic deletions in the 22q112 deletion syndrome as a model system  
  Tokuyasu TA, Cotter PD, Segraves R, Harris JM, Elder ME, Gonzales M, Pinkel D, Albertson, DG, Rauen KA, Am J Med Genet, 1/1/2007
• Recent thymic emigrants and subsets of na�ve and memory T cells in the circulation of patients with head and neck cancer  
  Kuss, I, Schaefer, C, Godfrey TE, Ferris, RL, Harris, JM, Gooding W, Whiteside TL, Clin Immunol, 1/1/2005
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Lectures

• Results from QUAIL: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Pilot Study of Quilizumab in Patients with Refractory Chronic Spontaneous Urticaria (CSU) 
  Barcelona, Spain - 1/7/2015

Other

• Molecular Heterogeneity, Biomarker Discovery, and Targeted Therapy in Asthma in Yao, Jallal and Ranade 
  Arron, JR and Harris, JM, Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care
  1/1/2014
• Monoclonal Antibodies in Anti-inflammatory Therapy in Crommelin, Sindelar and Meibohm 
  Harris, JM, Kuebler, P, Panzara MA, Pharmaceutical Biotechnology: Fundamentals & Applications – 3rd Ed
  1/1/2008
• Structural and immunological domain analysis of the carboxy-terminal tails of the high molecular weight neurofilament subunit proteins NF-M and NF-H (Dissertation) 
  Harris JM, University of Florida � College of Medicine � Department of Neuroscience
  1/1/1992