JeremyRichMD

PubMed

• Threonine fuels glioblastoma through YRDC-mediated codon-biased translational reprogramming.
  Xujia Wu, Huairui Yuan, Qiulian Wu, Yixin Gao, Tingting Duan, Kailin Yang, Tengfei Huang, Shuai Wang, Fanen Yuan, Derrick Lee, Suchet Taori, Tritan Plute, Søren Heisse...> ;Nature Cancer. 2024 Mar 22
• RBBP6 maintains glioblastoma stem cells through CPSF3-dependent alternative polyadenylation.
  Peng Lin, Wenyan Chen, Zhilin Long, Jichuan Yu, Jiayao Yang, Zhen Xia, Qiulian Wu, Xinyu Min, Jing Tang, Ya Cui, Fuyi Liu, Chun Wang, Jian Zheng, Wei Li, Jeremy N Rich...> ;Cell Discovery. 2024 Mar 19
• 3 citations
  Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism.
  Zhao, L., Qiu, Z., Yang, Z., Xu, L., Pearce, T., Wu, Q., Yang, K., Li, F., Saulnier, O., Fei, F., Yu, H., Gimple, R., Varadharajan, V., Liu, J., Hendrikse, L., Fong, V...> ;Nature Cancer. 2024 Jan 1
• 3 citations
  LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2'-O-methylation.
  Lihui Liu, Ziyang Liu, Qinghua Liu, Wei Wu, Peng Lin, Xing Liu, Yuechuan Zhang, Dongpeng Wang, Briana C Prager, Ryan C Gimple, Jichuan Yu, Weixi Zhao, Qiulian Wu, Wei ...> ;Nature Communications. 2023 Nov 18
• 6 citations
  EGFR promotes ALKBH5 nuclear retention to attenuate N6-methyladenosine and protect against ferroptosis in glioblastoma.
  Deguan Lv, Cuiqing Zhong, Deobrat Dixit, Kailin Yang, Qiulian Wu, Bhaskar Godugu, Briana C Prager, Guofeng Zhao, Xiuxing Wang, Qi Xie, Shideng Bao, Chuan He, Dieter He...> ;Molecular Cell. 2023 Dec 7
• 1 citations
  Watching the clock in glioblastoma.
  Priscilla Chan, Jeremy N Rich, Steve A Kay> ;Neuro-Oncology. 2023 Nov 2
• 16 citations
  Lysine catabolism reprograms tumour immunity through histone crotonylation.
  Huairui Yuan, Xujia Wu, Qiulian Wu, Adam Chatoff, Emily Megill, Jinjun Gao, Tengfei Huang, Tingting Duan, Kailin Yang, Chunyu Jin, Fanen Yuan, Shuai Wang, Linjie Zhao,...> ;Nature. 2023 May 1
• 5 citations
  A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis.
  Han Zou, Bradley Poore, Emily E Brown, Jieqi Qian, Bin Xie, Evridiki Asimakidou, Vladislav Razskazovskiy, Deanna Ayrapetian, Vaibhav Sharma, Shunjin Xia, Fei Liu, Apen...> ;Nature Cell Biology. 2023 Mar 1
• 23 citations
  Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle.
  Meng Qu, Guoxin Zhang, Han Qu, Alexander Vu, Raymond Wu, Hidekazu Tsukamoto, Zhenyu Jia, Wendong Huang, Heinz-Josef Lenz, Jeremy N Rich, Steve A Kay> ;Proceedings of the National Academy of Sciences of the United States of America. 2023 Jan 10
• 2 citations
  ABTC-0904: targeting glioma stem cells in GBM: a phase 0/II study of hedgehog pathway inhibitor GDC-0449.
  Andrew E Sloan, Charles J Nock, Xiaobu Ye, Robert Buerki, Susan Chang, Glenn Lesser, Andrew Norden, Timothy Cloughesy, Jeffrey Olson, Amber Kerstetter-Fogle, Jeremy Ri...> ;Journal of Neuro-Oncology. 2023 Jan 1
• Novel INHAT repressor drives glioblastoma growth by promoting ribosomal DNA transcription in glioma stem cells.
  Weiwei Tao, Hong Lei, Wenlong Luo, Zhi Huang, Peng Ling, Mengyue Guo, Lihao Wan, Kui Zhai, Qian Huang, Qiulian Wu, Shutong Xu, Liang Zeng, Xiuxing Wang, Zhiqiang Dong,...> ;Neuro-Oncology. 2023 Aug 3
• 2 citations
  Glioma stem cells activate platelets by plasma-independent thrombin production to promote glioblastoma tumorigenesis.
  Anthony R Sloan, Christine Lee-Poturalski, Harry C Hoffman, Peggy L Harris, Theresa E Elder, Brian Richardson, Amber Kerstetter-Fogle, Gino Cioffi, Julia Schroer, Ansh...> ;Neuro-Oncology Advances. 2022 Nov 7
• 23 citations
  PDGF signaling inhibits mitophagy in glioblastoma stem cells through N-methyladenosine.
  Deguan Lv, Ryan C Gimple, Cuiqing Zhong, Qiulian Wu, Kailin Yang, Briana C Prager, Bhaskar Godugu, Zhixin Qiu, Linjie Zhao, Guoxin Zhang, Deobrat Dixit, Derrick Lee, J...> ;Developmental Cell. 2022 Jun 20
• 2 citations
  Non-metabolic functions of phosphofructokinase-1 orchestrate tumor cellular invasion and genome maintenance under bevacizumab therapy.
  Yi Chieh Lim, Kamilla E Jensen, Diana Aguilar-Morante, Lina Vardouli, Kristoffer Vitting-Seerup, Ryan C Gimple, Qiulian Wu, Henriette Pedersen, Kirstine J Elbaek, Irin...> ;Neuro-Oncology. 2023 Feb 14
• 14 citations
  Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.
  Felker, J. T., Brian J Golbourn, Matthew E Halbert, Katharine Halligan, Srinidhi Varadharajan, Brian Krug, Nneka E Mbah, Nisha Kabir, Ann-Catherine J Stanton, Abigail ...> ;Nature Cancer. 2022 May 1
• 75 citations
  Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities.
  Abrar Choudhury, Stephen T Magill, Charlotte D Eaton, Briana C Prager, William C Chen, Martha A Cady, Kyounghee Seo, Calixto-Hope G Lucas, Tim J Casey-Clyde, Harish N ...> ;Nature Genetics. 2022 May 1
• 2 citations
  Patient-derived explants as tumor models.
  Christopher G Hubert, Jeremy N Rich> ;Cancer Cell. 2022 Apr 11
• 11 citations
  CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity.
  Davide Bernareggi, Qi Xie, Briana C Prager, Jiyoung Yun, Luisjesus S Cruz, Timothy V Pham, William Kim, Xiqing Lee, Michael Coffey, Cristina Zalfa, Pardis Azmoon, Huan...> ;Nature Communications. 2022 Apr 7
• 17 citations
  USP33 deubiquitinates and stabilizes HIF-2alpha to promote hypoxia response in glioma stem cells.
  Aili Zhang, Zhi Huang, Weiwei Tao, Kui Zhai, Qiulian Wu, Jeremy N Rich, Wenchao Zhou, Shideng Bao> ;The EMBO Journal. 2022 Apr 4
• 16 citations
  A FBXO7/EYA2-SCFaxis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells.
  Jia Z Shen, Zhixin Qiu, Qiulian Wu, Guoxin Zhang, Rebecca Harris, Dahui Sun, Juha Rantala, William D Barshop, Linjie Zhao, Deguan Lv, Kwang-Ai Won, James Wohlschlegel,...> ;Molecular Cell. 2022 Mar 17
• 23 citations
  ADAR1-mediated RNA editing links ganglioside catabolism to glioblastoma stem cell maintenance.
  Li Jiang, Yajing Hao, Changwei Shao, Qiulian Wu, Briana C Prager, Ryan C Gimple, Gabriele Sulli, Leo Jy Kim, Guoxin Zhang, Zhixin Qiu, Zhe Zhu, Xiang-Dong Fu, Jeremy N...> ;The Journal of Clinical Investigation. 2022 Mar 15
• 6 citations
  Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe
  Guoxin Zhang, Zhen Dong, Ryan C. Gimple, Arthur Wolin, Qiulian Wu, Zhixin Qiu, Lisa M Wood, Jia Z. Shen, Li Jiang, Linjie Zhao, Deguan Lv, Briana C. Prager, Leo J.Y. K...> ;The Journal of Experimental Medicine. 2021 Nov 1
• 56 citations
  Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase
  Zhen Xia, Min Tang, Jiayan Ma, Hongyan Zhang, Ryan C. Gimple, Briana C. Prager, Hongzhen Tang, Chongran Sun, Fuyi Liu, Peng Lin, Yutang Mei, Ruoxin Du, Jeremy N. Rich,...> ;Nucleic Acids Research. 2021 Jul 21
• 6 citations
  A delicate initiation: Lipolysis of lipid droplets fuels glioblastoma.
  Kailin Yang, Jeremy N. Rich> ;Molecular Cell. 2021 Jul 1
• 5 citations
  Phage display targeting identifies EYA1 as a regulator of glioblastoma stem cell maintenance and proliferation.
  Jongmyung Kim, Chunhua She, Marine Potez, Ping Huang, Qiulian Wu, Briana C. Prager, Zhixin Qiu, Shideng Bao, Jeremy N. Rich, James K. Liu> ;Stem Cells. 2021 Jul 1
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