JimmyHwangMD

Oncology • Charlotte, NC

Chief, GI Medical Oncology; Director Hematology/Oncology Fellowship; Levine Cancer Institute, Atrium Health

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Office
1021 Morehead Medical Dr
Suite 6100
Charlotte, NC 28204
Phone+1 980-442-6410

Fax+1 980-442-6141
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Education & Training

UPMC Medical EducationFellowship, Hematology and Medical Oncology, 1998 - 2001
UPMC Medical EducationResidency, Internal Medicine, 1995 - 1998
University of Pittsburgh School of MedicineClass of 1995

Certifications & Licensure

NC State Medical License 2013 - 2024
DC State Medical License 2001 - 2014
MD State Medical License 2010 - 2014
VA State Medical License 2001 - 2010
PA State Medical License 1996 - 2002
American Board of Internal Medicine Medical Oncology

Clinical Trials

An Open-Label Study of QD Oral Administration of Tivozanib (AV-951) in Subjects With Non-Small Cell Lung Cancer (NSCLC) Start of enrollment: 2009 Jan 01
Completed
Phase 1
A Phase 2 Study of Ramucirumab (LY3009806) in Participants With Gastric or Gastroesophageal Junction (GEJ) Cancer Start of enrollment: 2015 Jul 07
Completed
Phase 2
A Study of Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies Start of enrollment: 2016 Feb 19
Completed
Phase 1
AGEN1884, an Anti-CTLA-4 Human Monoclonal Antibody in Subjects With Advanced or Refractory Cancer and Who Have Progressed With PD-1/PD-L1 Inhibitor as Their Most Recent Therapy Start of enrollment: 2016 Apr 01
Completed
Phase 1, Phase 2
A Study to Test Different Doses of BI 1701963 Alone and Combined With Trametinib in Patients With Different Types of Advanced Cancer (Solid Tumours With KRAS Mutation) Start of enrollment: 2019 Oct 28
Active, not recruiting
Phase 1
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Publications & Presentations

PubMed

Predictive value of CDC37 gene expression for targeted therapy in metastatic colorectal cancer.
Hiroyuki Arai, Yan Yang, Yasmine Baca, Joshua Millstein, Tadamichi Denda, Fang-Shu Ou, Federico Innocenti, Hiroyuki Takeda, Yohei Kubota, Ayako Doi, Yoshiki Horie, Kum...> ;European Journal of Cancer. 2024 Apr 1
1 citations
COVID-19 vaccine uptake trends in SARS-CoV-2 previously infected cancer patients.
Zainab Shahid, Alicia L Patrick, Michelle L Wallander, Erin E Donahue, Sally J Trufan, Antoinette R Tan, Jimmy J Hwang, Earle F Burgess, Brittany Ragon, Nilanjan Ghosh...> ;Vaccine. 2023 Aug 1
2 citations
Addressing barriers to increased adoption of DPYD genotyping at a large multisite cancer center.
Sarah A Morris, Donald C Moore, Laura W Musselwhite, Karine Eboli Lopes, Alicia Hamilton, Nury Steuerwald, Sarah L Hanson, Chris Larck, Kristen Swift, Mathew Smith, Ku...> ;American Journal of Health-System Pharmacy. 2023 Sep 22
Peritoneal metastases from primary appendiceal and colorectal carcinomas demonstrate distinct molecular identities on comprehensive tumor analysis.
Andrew M Fleming, Benjamin W Deschner, Forrest W Williard, Justin A Drake, Ari Vanderwalde, Joanne Xiu, Bradley G Somer, Danny Yakoub, Miriam W Tsao, Evan S Glazer, Pa...> ;Journal of Surgical Oncology. 2023 Apr 1
2 citations
Impact of a Clinical Genomics Program on Trial Accrual for Targeted Treatments: Practical Approach Overcoming Barriers to Accrual for Underserved Patients.
Carol J Farhangfar, Gregory T Scarola, Victoria A Morris, Farhang Farhangfar, Kathryn Dumas, James Symanowski, Jimmy J Hwang, Kathryn F Mileham, Daniel R Carrizosa, R ...> ;JCO Clinical Cancer Informatics. 2022 Jul 1
37 citations
Molecular Characterization of KRAS Wild-type Tumors in Patients with Pancreatic Adenocarcinoma.
Philip A Philip, Ibrahim Azar, Joanne Xiu, Michael J Hall, Andrew Eugene Hendifar, Emil Lou, Jimmy J Hwang, Jun Gong, Rebecca Feldman, Michelle Ellis, Phil Stafford, D...> ;Clinical Cancer Research. 2022 Jun 13
64 citations
Somatic Genomic Testing in Patients With Metastatic or Advanced Cancer: ASCO Provisional Clinical Opinion.
Debyani Chakravarty, Amber Johnson, Jeffrey Sklar, Neal I Lindeman, Kathleen Moore, Shridar Ganesan, Christine M Lovly, Jane Perlmutter, Stacy W Gray, Jimmy Hwang, Chr...> ;Journal of Clinical Oncology. 2022 Apr 10
37 citations
Landscape of, Associated Genomic Alterations, and Interrelation With Immuno-Oncology Biomarkers in-Mutated Cancers.
Mohamed E Salem, Sherif M El-Refai, Wei Sha, Alberto Puccini, Axel Grothey, Thomas J George, Jimmy J Hwang, Bert O'Neil, Alexander S Barrett, Kunal C Kadakia, Laura W ...> ;JCO Precision Oncology. 2022 Mar 1
5 citations
Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic colorectal cancer.
Hiroyuki Arai, Andrew Elliott, Joshua Millstein, Joanne Xiu, Fang-Shu Ou, Federico Innocenti, Jingyuan Wang, Francesca Battaglin, Priya Jayachandran, Natsuko Kawanishi...> ;Oncogene. 2021 Nov 2
2 citations
Association of Homologous Recombination-DNA Damage Response Gene Mutations with Immune Biomarkers in Gastroesophageal Cancers.
Michael Cerniglia, Joanne Xiu, Axel Grothey, Michael J. Pishvaian, Yasmine Baca, Jimmy J. Hwang, John L. Marshall, Ari M. Vanderwalde, Anthony F. Shields, Heinz-Josef ...> ;Molecular Cancer Therapeutics. 2021 Nov 1
8 citations
Molecular characterization of squamous cell carcinoma of the anal canal
Samantha A Armstrong, Rita Malley, Hongkun Wang, Heinz-Josef Lenz, David Arguello, Wafik S. El-Deiry, Joanne Xiu, Zoran Gatalica, Jimmy J. Hwang, Philip A. Philip, Ant...> ;Journal of Gastrointestinal Oncology. 2021 Oct 1
12 citations
Impact of Sociodemographic Disparities and Insurance Status on Survival of Patients with Early-Onset Colorectal Cancer.
Mohamed E. Salem, Alberto Puccini, Sally Jeanne Trufan, Wei Sha, Kunal C. Kadakia, Marion L. Hartley, Laura W. Musselwhite, James T. Symanowski, Jimmy J. Hwang, Derek ...> ;The Oncologist. 2021 Oct 1
8 citations
The treatment sequence may matter in patients undergoing pancreatoduodenectomy for early stage pancreatic cancer in the era of modern chemotherapy.
Michael D Watson, Kyle J. Thompson, Laura W. Musselwhite, Jimmy J. Hwang, Erin H. Baker, John B. Martinie, Dionisios Vrochides, David A. Iannitti, Lee M. Ocuin> ;American Journal of Surgery. 2021 Jul 1
2 citations
Early-onset pancreatic cancer: an institutional series evaluating end-of-life care.
Kunal C. Kadakia, Sally Jeanne Trufan, Megan Jagosky, William M Worrilow, Bradley W. Harrison, Katherine Broyhill, Jimmy J. Hwang, Laura W. Musselwhite, Aynur Aktas, D...> ;Supportive Care in Cancer. 2021 Jul 1
16 citations
Large-scale analysis of KMT2 mutations defines a distinctive molecular subset with treatment implication in gastric cancer.
Jingyuan Wang, Joanne Xiu, Yasmine Baca, Francesca Battaglin, Hiroyuki Arai, Natsuko Kawanishi, Shivani Soni, Wu Zhang, Joshua Millstein, Bodour Salhia, Richard M. Gol...> ;Oncogene. 2021 Jun 23
24 citations
The Landscape of Alterations in DNA Damage Response Pathways in Colorectal Cancer.
Hiroyuki Arai, Andrew Elliott, Joanne Xiu, Jingyuan Wang, Francesca Battaglin, Natsuko Kawanishi, Shivani Soni, Wu Zhang, Joshua Millstein, Davendra Sohal, Richard M. ...> ;Clinical Cancer Research. 2021 Mar 25
10 citations
A phase I trial of the mTOR inhibitor temsirolimus in combination with capecitabine in patients with advanced malignancies
Neel D. Trivedi, Samantha A Armstrong, Hongkun Wang, Marion Hartley, John F. Deeken, A. Ruth He, Deepa S. Subramaniam, Heather Melville, Chris Albanese, John L. Marsha...> ;Cancer Medicine. 2021 Feb 27
14 citations
Conversion therapy for intrahepatic cholangiocarcinoma and tumor downsizing to increase resection rates: A systematic review.
M. Fruscione, R.C. Pickens, Erin H. Baker, John B. Martinie, David A. Iannitti, Jimmy J. Hwang, Dionisios Vrochides> ;Current Problems in Cancer. 2021 Feb 1
39 citations
Comprehensive genomic profiling of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs)
Alberto Puccini, Kelsey Poorman, Mohamed E. Salem, Davide Soldato, Andreas Seeber, Richard M. Goldberg, Anthony F. Shields, Joanne Xiu, Francesca Battaglin, Martin D. ...> ;Clinical Cancer Research. 2020 Nov 15
34 citations
The impact of ARID1A mutation on molecular characteristics in colorectal cancer.
Ryuma Tokunaga, Joanne Xiu, Richard M. Goldberg, Philip A. Philip, Andreas Seeber, Francesca Battaglin, Hiroyuki Arai, Jae Ho Lo, Madiha Naseem, Alberto Puccini, Marti...> ;European Journal of Cancer. 2020 Nov 1
9 citations
Molecular Characterization of Appendiceal Goblet Cell Carcinoid
Hiroyuki Arai, Yasmine Baca, Francesca Battaglin, Natsuko Kawanishi, Jingyuan Wang, Shivani Soni, Wu Zhang, Joshua Millstein, Curtis Johnston, Richard M. Goldberg, Phi...> ;Molecular Cancer Therapeutics. 2020 Oct 9
15 citations
A phase 1 dose-escalation study of checkpoint kinase 1 (CHK1) inhibitor prexasertib in combination with p38 mitogen-activated protein kinase (p38 MAPK) inhibitor ralim...
Johanna C. Bendell, Helge Bischoff, Jimmy Hwang, Hans Christian Reinhardt, Thomas Zander, Xuejing Wang, Scott M. Hynes, Celine Pitou, Robert M. Campbell, Philip W. Ive...> ;Investigational New Drugs. 2020 Aug 1
22 citations
A Phase I/II Study of Veliparib (ABT-888) in combination with 5-Fluorouracil and Oxaliplatin in Patients with Metastatic Pancreatic Cancer
Michael J. Pishvaian, Hongkun Wang, Aiwu Ruth He, Jimmy J. Hwang, Brandon G. Smaglo, Sunnie S. Kim, Benjamin A. Weinberg, Louis M. Weiner, John L. Marshall, Jonathan R...> ;Clinical Cancer Research. 2020 Oct 1
1 citations
Advances in borderline resectable pancreatic adenocarcinoma.
Deepak Vadehra, Patrick N. Salibi, Derek R McHaffie, Jesse K Sulzer, David A. Iannitti, Jimmy J. Hwang> ;Clinical Advances in Hematology & Oncology. 2020 May 1
14 citations
Comprehensive tumor profiling reveals unique molecular differences between peritoneal metastases and primary colorectal adenocarcinoma.
Matthew K Stein, Forrest W Williard, Joanne Xiu, Miriam W. Tsao, Michael Gary Martin, Benjamin W. Deschner, Paxton V. Dickson, Evan S. Glazer, Danny Yakoub, David Shib...> ;Journal of Surgical Oncology. 2020 Mar 12
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Abstracts/Posters

A Phase 1b Dose Escalation Trial of Carfilzomib in Combination with Bendamustine and Rituximab in Patients with Relapsed or Refractory Non-Hodgkin Lymphoma
Jimmy Hwang, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Authored Content

ASCO GI: Updates in Rectal Cancer and the FIGHT StudyJanuary 2021

Press Mentions

Early Discovery of Liver Disease Improves Chances to Cure Liver CancerOctober 21st, 2021
ASCO GI: Updates in Rectal Cancer and the FIGHT StudyJanuary 25th, 2021
I’ll Never Stop FightingAugust 22nd, 2019
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Hospital Affiliations

Atrium Health's Carolinas Medical CenterCharlotte, North Carolina