JohannesE.WolffMDDr. med. habil. MD PhD(He/Him)

PubMed

• 2 citations
  Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients.
  Junichiro Yuda, Christine Will, Darren C Phillips, Linu Abraham, Cory Alvey, Abraham Avigdor, Wayne Buck, Lauren Besenhofer, Erwin Boghaert, Dong Cheng, Dan Cojocari, ...> ;Communications Medicine. 2023 Oct 25
• Vaccine Preventable Diseases in Pediatric Palliative Care - A Multicenter Cross-Sectional Study.
  Vera Vaillant, Irina Tretiakova, Daniel Berthold, Mario Scheer, Astrid Kimmig, Andrea Hagenguth, Jens Kaestner, Andrea Meinhardt, Peter Kriwy, Holger Hauch, Johannes W...> ;Journal of Pain and Symptom Management. 2023 Feb 1
• Editorial: Emergency medicine in pediatric patients with chronic diseases.
  Emmanuel Schneck, Johannes Wolff, Jan-Thorsten Graesner, Holger Hauch> ;Frontiers in Pediatrics. 2023 Jan 1
• 2 citations
  Prehospital emergency medicine for children receiving palliative home care in Germany-a cross-sectional, exploratory study of EMS providers.
  Holger Hauch, Naual El Mohaui, Vera Vaillant, Michael Sander, Peter Kriwy, Marius Rohde, Johannes Wolff, Daniel Berthold, Emmanuel Schneck> ;Frontiers in Pediatrics. 2023 Jan 1
• 2 citations
  Co-clinical Modeling of the Activity of the BET Inhibitor Mivebresib (ABBV-075) in AML.
  Daniel H Albert, Neal C Goodwin, Angela M Davies, Jenny Rowe, Gerold Feuer, Michael Boyiadzis, Kathleen A Dorritie, Maria Mancini, Regina Gandour-Edwards, Brian A Jona...> ;In Vivo. 2022 Jun 23
• Adverse Events in Placebo Arms of Cancer Trials.
  Johannes E Wolff, Birte J Wolff, Marceal M Thielen, Holger Hauch> ;Anticancer Research. 2022 Jun 1
• 9 citations
  Final results of the Choroid Plexus Tumor study CPT-SIOP-2000.
  Johannes E Wolff, Stefaan W Van Gool, Tezer Kutluk, Blanca Diez, Rejin Kebudi, Beate Timmermann, Miklos Garami, Jaroslav Sterba, Gregory N Fuller, Brigitte Bison, Uwe ...> ;Journal of Neuro-Oncology. 2022 Feb 1
• 2 citations
  Clinical characteristics, late effects and outcomes in pineoblastomas in children: a single center experience.
  Ömer Görgün, Başak Koç, Rejin Kebudi, Johannes E Wolff, Abut Kebudi, Emin Darendeliler> ;The Turkish Journal of Pediatrics. 2022 Jan 13
• 2 citations
  Fatigue in Cancer Treatment Studies: Analysis of Placebo Arms.
  Holger Hauch, Birte J Wolff, Johannes E Wolff> ;Anticancer Research. 2022 Jan 1
• 2 citations
  Diarrhea in Placebo Arms of Cancer Studies.
  Birte J Wolff, Johannes E Wolff> ;Cancer Diagnosis & Prognosis. 2021 Nov 3
• 3 citations
  Anemia in Placebo Arms of Cancer Studies.
  Johannes E. A. Wolff> ;Anticancer Research. 2021 Sep 1
• 5 citations
  Headache Reporting in Oncology Trials Depends on the Demographics of the Study Population.
  Birte J Wolff, Matthaeus J Wolff, Johannes E. A. Wolff> ;In Vivo. 2021 Jul 1
• 10 citations
  Alveolar rhabdomyosarcoma: morphoproteomics and personalized tumor graft testing further define the biology of PAX3-FKHR(FOXO1) subtype and provide targeted therapeuti...
  Robert E. Brown, Jamie Buryanek, Amanda Katz, Keren Paz, Johannes E. Wolff> ;Oncotarget. 2016 Jun 15
• 4 citations
  Bilateral perioptic nerve lesions in a patient with Langerhans-cell histiocytosis.
  Vernon Ho Yuen, David R. Jordan, Seymour Brownstein, Michael W. Dorey, Johannes E. A. Wolff, Anna L. Ells, Michael Ashenhurst, R. Maarten Egeler> ;Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie. 2003 Oct 1
• 21 citations
  Langerhans' cell histiocytosis with bilateral temporal bone involvement.
  Tobias Kleinjung, Matthias Woenckhaus, Maike Bachthaler, Johannes E.A Wolff, Stephan R Wolf> ;American Journal of Otolaryngology. 2003 Jul 1
• 5 citations
  Multifocal desmoplastic astrocytoma, frontal lobe dysplasia, and simian crease.
  Dirk Bock, P. Rümmele, Martin Friedrich, Johannes E.A. Wolff> ;The Journal of Pediatrics. 2002 Sep 1
• 21 citations
  Further evidence for genetic heterogeneity in familial hemophagocytic lymphohistiocytosis (FHLH).
  Gail E. Graham, Lisa Graham, Peter Bridge, Linda MacLaren, Johannes E. A. Wolff, Max J. Coppes, R. Maarten Egeler> ;Pediatric Research. 2000 Aug 1
• 25 citations
  Long-term complications and post-treatment follow-up of patients with Wilms' tumor.
  R. M. Egeler, Johannes E. A. Wolff, Ronald Anderson, Max J. Coppes> ;Seminars in Urologic Oncology. 1999 Feb 1
• 58 citations
  Alternative Therapies for the Treatment of Childhood Cancer
  Max J. Coppes, Ronald Anderson, R. M. Egeler, Johannes E. A. Wolff> ;The New England Journal of Medicine. 1998 Sep 17
• 10 citations
  Gamma-glutamyl transpeptidase does not act as a cystine transporter in brain microvessels.
  Johannes E. A. Wolff, Gudrun Münstermann, Kai Grebenkämper, Martin Erben> ;Neurochemical Research. 1998 Sep 1
• 37 citations
  Inhibition of hypercoagulation by antithrombin substitution in E. coli L‐asparaginase‐treated children
  Ulrike Nowak-Göttl, N. Kuhn, Johannes E. A. Wolff, Joachim Boos, B. Kehrel, B. Rath, Heribert Jürgens> ;European Journal of Haematology. 2009 Apr 24
• 45 citations
  Dexamethasone reduces vascular density and plasminogen activator activity in 9L rat brain tumors.
  Johannes E.A. Wolff, Christopher Guerin, John Laterra, Joseph Bressler, Ravi R. Indurti, Henry Brem, Gary W. Goldstein> ;Brain Research. 1993 Feb 26
• 14 citations
  Modulation of glial cell differentiation by exposure to lead and cadmium.
  M. Stark, J.E.A. Wolff, A. Korbmacher> ;Neurotoxicology and Teratology. 1992 Jul 1
• 34 citations
  Steroid Inhibition of Neural Micro vessel Morphogenesis In Vitro: Receptor Mediation and Astroglial Dependence
  Johannes E. A. Wolff, John Laterra, Gary W. Goldstein> ;Journal of Neurochemistry. 1992 Mar 1
• 30 citations
  γ-glutamyl transpeptidase activity in brain microvessels exhibits regional heterogeneity
  Johannes E. A. Wolff, Luisa Belloni-Olivi, Joseph Bressler, Gary W. Goldstein> ;Journal of Neurochemistry. 1992 Mar 1
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Journal Articles

• Anemia in Placebo Arms of Cancer Studies  
  Johannes E Wolff, Anticancer Research August 2021 41(9): 4543-4548, 2021
• Late Effects And Outcome In Pineoblastomas In Children: A Single Center Experience  
  211. Başak Koç Johannes Wolff, R Kebudi, ÖG, RK, BK, SBB, AK, ED, The Turkish Journal of Pediatrics, 2021
• Anemia in Placebo Arms of Cancer Studies  
  Johannes E Wolff, Anticancer Research, 2021
• High-resolution genomic analysis does not qualify atypical plexus papillomas as separate entity among choroid plexus tumors  
  Japp AS, Gessi M, Messing-Jünger M, Denkhaus D, Zur Mühlen A, Wolff JE, Hartung S, Kordes U, Klein-Hitpass L, Pietsch T, Journal of Neuropathology and Experimental Neurology, 1/1/2014
• Pediatric high grade glioma: Identifying which patients can be helped with chemotherapy  
  Wolff JE, Brain Tumour IBTA Edition, 1/1/2013
• Choroid Plexus Tumor  
  Kordes. U, Warmuth-Metz. M, Hasselblatt. M. Wolff. JE, Oncopedia, 1/1/2012
• Salvage craniospinal irradiation with an intensity modulated radiotherapy technique for patients with disseminated neuraxis disease  
  Mahajan, Anita, Randy Wei, Son T Nguyen, Johannes Wolff, Practical Radiation Oncology, 1/1/2012
• SIOP Choroid plexus tumor meeting minutes 2011  
  Wolff JE Kebudi et al, SIOP NEWS, 1/1/2011
• Cooperative study group for childhood acute lymphoblastic leukemia (COALL): long term results of trials 82,85,89,92 and 97  
  Escherich G, MA Hostmann MA, …Wolff J…GE Janka-Schaub, Leukemia, 1/1/2011
• Valproic acid as a potent substance for increasing efficacy of topoisomerase I inhibitors  
  Wagner, S; Stefaan Van Gool, Peter Hau, Torsten Pietsch, Ove Peters, Wolff JE, Turkish Journal of Cancer, 1/1/2011
• Canine Astrocytic Tumors: A Comparative Review  
  Stoica G, Levine J, Wolff J, Murphy K, Vet Pathol, 1/1/2011
• Dose-Time-Effect Modeking for Cancer Cell Growth in in-vitro experiments  
  Kong, Maiying; Zhang M. Gopalakrishnan V, and Wolff JE, Statistics in Biopharmaceutical Research, 1/1/2010
• Chromatin remodeling at the topoisomerase II-beta promoter is associated with enhanced sensitivity to etoposide in human neuroblastoma cell lines  
  Das, C; Zage, PE; Taylor, P; Aguilera, D, Wolff JE; Lee, D, Gopalakrishnan, V, Eur J Cancer, 1/1/2010
• Choroid plexus tumor meeting February 2009 Houston  
  Wolff JE, Berrak S, Wrede B, SIOP NEWS, 1/1/2009
• Choroid Plexus Tumor Study Committee Meeting 2009  
  Wolff JE, Tezer Kutluk, SIOP NEWS, 1/1/2009
• Introduction First international choroid plexus tumor research meeting  
  Wolff JE, Brigitte Wrede, Su Berrak, Tezer Kutluk, Turkish Journal of Cancer, 1/1/2009
• First international choroid plexus tumor research meeting Minutes  
  Wolff JE, Rejin Kebudi, Michael Rytting, Brigitte Wrede, Turkish Journal of Cancer, 1/1/2009
• Hochmaligne Gliome im Kindes- und Jugendalter  
  C. Kramm, U. Rausche, S. Butenhoff, C. Kuhnol C,. Kunze, R. Kortmann J. Wolff, S. van Gool, Monatsschr Kinderheilkd, 1/1/2009
• Hochmaligne Gliome im Kindes- und Jugendalter  
  Kramm CM, U. Rausche, S. Butenhoff, C. D. Kühnöl, C. Kunze, R.-D. Kortmann, J. E. A. Wolff, S. van Gool, Monatsschrift fur Kinderheilkunde, 1/1/2008
• Choroid Plexus Tumor Meeting, 39th SIOP Congress in Mumbai, India  
  Wrede B, Wolff J, Peters O, SIOP News, 1/1/2008
• Phase I clinical trials in children  
  Morgan LR, Wolff JE, Nagel P, Cure, 1/1/2008
• Nitrosourea efficacy in high- grade glioma: A survival gain analysis summarizing 504 cohorts with 24193 patients  
  Wolff JE, Berrak S, and Koontz Webb SE, Zhang M, J Neurooncol, 1/1/2008
• Tumor-banking in den Multizentrischen Therapie- Optimierungsstudien der Gesellschaft fur Padiatrische Onkologie und Hamatologie (GPOH) fur Kinder und Jugendliche mit H...  
  Rutkowski S, Gnekow A, Bode U, Kramm C, Wagner S, Calaminus G, Muller H, Wolff J, Fruhwald M, Pietsch T, for the German Pediatric Brain Tumor Study Group of the GPOH, Mannheim Dt. Ges. f. Neuropathologie, 1/1/2006
• Childhood brain tumors: Standards and recent developments in diagnostics and treatment (Hirntumoren bei Kindern und Jugendlichen: Standards und neue Entwicklungen in D...  
  Rutkowski S, Gnekow A, Fleischhack G, Wagner S, Calaminus G, Wolff J, Muller H, Sorensen N, Faldum A, Tatagiba M, Pietsch T, Warmuth-Metz M, Kortmann R, Der Onkologe, 1/1/2006
• Treatment arms summarizing analysis of 220 high- grade glioma studies  
  Hauch H, Sajedi M, Wolff JE, Anticancer Res, 1/1/2005
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Books/Book Chapters

• Tumors in Children 
  Chapter: Medical Management in Choroid Plexus Tumors in Posterior Fossa 
  Page 745 - 760Johannes E. Wolff, Mical Bahar, Anita Mahajan, and Su G. BerrakSpringer, Heidelberg2015
• Molecular Pathology of Nervous System Tumors - Biological Stratification and Targeted Therapies 
  Chapter: Choroid plexus tumors 
  Vennet S, Hasselblatt M, Wolff JE, Judkins AREditors: Karajannis, Matthias A., Zagzag, David.Springer2015
• Pediatric Perspectives - Cleveland Clinic Children’s 
  Chapter: Personalized targeted Therapy for Pediatric malignancies: Progress lies in networked data collection and analysis 
  Page 18 - 20Wolff JE2015
• HIT-GBM-D English 
  Wolff JEBook Wolff Publishing, Missouri City, TXEdition 2nd,2010
• CPT-SIOP-2000 protocol 
  Wolff JEBook Wolff Publishing, Missouri City, TX2010
• HIT-GBM-D Deutsch 
  Wolff JEBook Wolff Publishing, Missouri City, TXEdition 2nd,2010
• HIT-GBM-A. 2. Auflage 
  Wolff JEBook Wolff Publishing, Missouri City, TX2010
• HIT-GBM-C 2. Auflage 
  Wolff JEBook Wolff Publishing, Missouri City, TX2010
• Cancer in Children 
  Chapter: Choroid Plexus Tumors 
  Page 299 - 302Wolff JE, Finlay JEditors: Carroll WL & Finlay JL.Jones & Bartlett Publishers2009
• Leitlinien der Kinder- und Jugendmedizin 
  Chapter: Hochgradig maligne Gliome und Ponsgliome im Kindes- und Jugendalter 
  Page 1 - 10Kramm C, Wolff JEEditors: Wirth et al.Urban & Fischer publisher2009
• Therapie in der Kinder-und Jugendmedizin, (Therapy in Children’s and Adolescence medicine) 
  Chapter: Hirntumoren 
  Page 863 - 870Wolff JEEditors: Kiess W. Merkenschlager A. Pfaeffle R. Siekenmeyer W.Urban und Fischer2008
• Therapie der Krankheiten des Kindes- und Jugendalters 
  Chapter: Hirntumoren 
  Page 1756 - 1772Kramm CM, Wolff JEEditors: Reinhardt.Springer Medizin Verlag Heidelberg, Germany2008
• Therapie der Krankheiten des Kindes- und Jugendalters 
  Chapter: Tumoren des Ruckenmarks 
  Page 1773 - 1775Kramm CM, Wolff JEEditors: Reinhardt.Springer Medizin Verlag Heidelberg, Germany2007
• Brain and spinal tumors of childhood 
  Chapter: High grade glioma 
  Wolff JE, Chastagner PEditors: Walker, Perilongo, Punt and Taylor.Arnold publishers, New York2004
• Journal Onkologie 
  Chapter: Multimodale Therapiekonzepte fur Kinder und Jugendliche mit Hirntumoren 
  Rutkowski S, Gnekow A., Wolff J2004
• Qualitatssicherung in der Onkologie: Empfehlungen der Projektgruppen im Tumorzentrum Regensburg 
  Chapter: ZNS Tumoren in Kindesalter 
  Wolff JE, Wagner SV. Studiodruck Regensburg2003
• Hochgradige Gliome und Ponsglome im Kindes- und Jugendalter 
  Chapter: Leitlinien der Deutschen Krebsgesellschaft und der Deutschen Gesellschaft fur Padiatrische Onkologie und Hamatologie (GPOH) 
  Wolff JEW. Zuckschwerdt Verlag2002
• Kompendium Internistische Onkologie, 2 
  Chapter: Childhood brain tumors (Hirntumoren im Kindesalter) 
  Wolff JE, Jurgens H, Kuhl J, Krauseneck, P, Egeler, MEditors: Schmoll, Hoffken, Possinger, Hsg.Springer Verlag Heidelberg1999
• ODIN Multimedia 
  Chapter: Maligne Gliome bei Kindern. (malignant glioma on children) 
  Wolff JEBertelsmann Springer1999
• Experimentelle Neuroonkologie III 
  Editors: Wolff JE.Zuckschwerdt Verlag, Munchen, New York1997
• Experimentelle Neuroonkologie II: Abstractband 
  Editors: Wolff JE.Zuckschwerdt Verlag, Munchen, New York1996
• Kompendium internistischer Onkologie, 2 
  Chapter: (Brain tumors in children) Hirntumoren im Kindesalter 
  Wolff JE, Kuhl J, Bamberg M, Krauseneck PEditors: Schmoll, Hoffken, Possinger, Hsg.Springer, Heidelberg1996
• Experimentelle Neuroonkologie, Abstractband 
  Editors: Wolff JE.Zuckschwerdt Verlag, Munchen, New York1995
• Glutamate- Transmitter und Toxin 
  Chapter: ("Die Entwicklung der Blut-Hirn Schranke: Barriere fur Glutamat"). (The development of the blood brain barrier) 
  Wolff JEEditors: Kemski O.Zuckschwerdt Verlag, Munchen, New York1994
• Glutamate - Transmitter and Toxin 
  Chapter: The blood-brain barrier: Development and glutamate permeability 
  Wolff JEEditors: Kemski O.Zuckschwerdt Verlag, Munchen, New York1993
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Abstracts/Posters

• Biomarker Modulation By Mivebresib (ABBV-075) +/_ Venetoclax in Relapsed/Refractory Acute Myeloid Leukemia
  Johannes E. Wolff, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Choroid Plexus Tumors in Adult and Pediatric Populations
  Bahar M, Hashem H, DeBlank P, Wolff J, The Case Comprehensive Cancer Center Experience, 1/1/2015
• Intercontinental multidisciplinary data collection and treatment optimization study for patients with choroid plexus tumors
  Bahar M, Kordes U, Wolff J, SNO, 1/1/2015
• Apparent diffusion coefficient measurement in patients with diffuse intrinsic pontine gliioma (DIPG): Work-in- progress
  Mahmoud, Shamseldeen, Tekautz, Tanya, Wadhwa, Aman, Jones, Stephen E., Ruggieri, Paul ,Murphy, Erin , Wolff, Johannes, SNO, 1/1/2015
• Lumbar spinal atypical teratoid rhabdoid tumor- case report
  Dhir, Aditi; Tekautz, Tanya; Wlff, Johannes, SNO, 1/1/2015
• No Radiation for Choroid Plexus Tumor Patients with Li Fraumeni Syndrome ?
  Michal Bahar, MD, Uwe Kordes, MD, Johannes E. Wolff, MD, SIOP, 1/1/2014
• Neurocytoma: the Cleveland Clinic experience
  Tekautz T, Chao S, Recinos V, Murphy E, Barnett G, Wolff J, SIOP, 1/1/2014
• Tumor Cells in the Cerebrospinal Fluid in Low Grade Choriod Plexus Tumor: Do Not Overtreat!
  U.R Kores, M. Benesh, S. Hartung, K. Petasch, S. Rutkowski, V. Ruland, t. Pietsch, M. Hasselblatt, J.E.A. Wolff, SIOP, 1/1/2014
• Report for the SIOP- CPT 2000 Study and the Current SIOP-CPT Registry
  U.R. Kordes, S. Hartung, M. Hasselblatt, V. Ruland, T. Pietsch, R.D. Kortmann, M. Warmuth-Metz, M. Garami, H. Traunecker, J.E.A. Wolff, SIOP, 1/1/2014
• Pinealoblastomas
  R. Kebudi, B. Koc, F. Yaman Agaoglu, O. Gorgun, J. Wolff, S. Bay Kapu, A. Kebudi, E. Darendeliler, SIOP, 1/1/2014
• Running Title- Topotecan, Ifosfamide, Carboplatin
  Radhakrishnan K, Lee A, Harrison L.A., Morris E, Shen V, Gates L, Wells RJ, Wolff JE, Garvin JH, Cairo MS, ASCO meeting, Chicago, IL, 1/1/2010
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Lectures

• Neruooncology/ Targeted Therapy 
  London, Ontario - 1/11/2014
• Anemia 
  Erie, PA - 1/10/2014
• Personalized Targeted In Oncology- First. Data 
  Boston, MA - 1/30/2011
• Molecular Targeted Therapy 
  1/28/2010
• Brain Tumors in Children 
  Boston, MA - 1/20/2010
• Response, a New Endpoint for Clinical Trials 
  1/5/2010
• Choroid Plexus Tumors, RDE negotiations 
  1/14/2009
• The Developing Brain: neurooncology, pharmacokinetics 
  1/1/2009
• Treatment of Childhood Brain Tumors 
  Houston, TX - 1/19/2007
• Valproate and Etoposide oral treatment for relapsed and progressive brain tumors and brain metastases 
  Houston, TX - 1/12/2007
• EGFR – Antibody Treatment of High-Grade Glioma in Children 
  1/1/2006
• Thalamic Astrocytoma 
  1/17/2005
• Pediatric Oncology, Pediatric Residents: Bedside Teaching Pediatric Oncology 
  1/1/2000
• Kursus fur spezielle Pathologie, Teil: Neuropathologie, 2 Abschnitt des klinischen Studiums 
  1/1/1999
• Klinischer Untersuchungskurs, Teil Padiatrie, 1. Abschnitt des klinischen Studiums 
  1/1/1997
• Interdisziplinäres Seminar für experimentelle Neuroonkologie 
  1/1/1997
• Praktischer Kursus zum Arzt - Patienten Verhaltnis fur Studierende der vorklinischen Semester 
  1/1/1997
• Kursus fur padiatrische Onkologie fur Kinderkrankenschwestern 
  1/1/1997
• Assistenzarzte in Facharztausbildung: Padiatrische Hamatologie, Onkologie 
  1/1/1997
• Kursus fur Kinderheilkunde fur Medizinstudenten 2 Abschnitt des klinischen Studiums 
  1/1/1989
• Krankengymnastikschule der Universitats- - Kliniken Dusseldorf: Padiatrie inklusive Staatsexamens - Prufung 
  1/1/1988
• Symposium and Workshops on Food Acquisition and Processing in Primates 
  Cambridge, UK - 1/1/1982
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Other

• Standard Operating Procedure (SOP) for personalized targeted therapy 
  J Wolff
  1/1/2013
• Constitution CAPT: Cancer Alliance of Pediatric Targeted therapy 
  J Wolff
  1/1/2013
• Targeted Therapy in Pediatric Oncology 
  Wolff JE, Cleveland Clinic Manual
  1/1/2013
• Wolff notes 
  J Wolff
  http://personalizedcancercareinstitute.com
  1/1/2012
• Leitlinien Medulloblastoma 
  J Wolff, Tumorzentrum Regensburg
  1/1/2008
• MDACC: Pediatric Neurooncology Fellowship program 
  J Wolff, State Accreditation- Texas
  Houston, TX - 1/1/2006
• CPT-SIOP-2000 Study - SIOP News 
  Wolff JEA, Wrede, B, Choroid Plexus Tumor Study Committee Meeting
  Vancouver, Canada - 1/1/2005
• 300 practice exam questions for Pediatric Neurooncology 
  J Wolff
  Calgary - 1/1/2003
• Teaching manual for medical student for the class pediatric Oncology 
  J Wolff
  Regensburg, Germany - 1/1/2003
• Neurooncology 
  J Wolff & Albert Moghrabi, Pediatric Oncology Board Certification
  Canada - 1/1/1999
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