JohnBaxterMD

PubMed

• Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown Fat.
  Lin, J. Z.,Martagón, A. J.,Cimini, S. L.,Gonzalez, D. D.,Tinkey, D. W.,Biter, A.,Baxter, J. D.,Webb, P.,Gustafsson, JÅ.,Hartig, S. M.,Phillips, K. J.> ;Cell Rep. 2015 Nov 21
• Nucleoside-sparing antiretroviral regimens.
  de la Torre, P.,George, J.,Baxter, J. D.> ;Curr Infect Dis Rep. 2014 Jun 02
• 72 citations
  Thyroid hormone receptor-β agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways
  Daniel F. Vatner, Dirk Weismann, Sara A. Beddow, Naoki Kumashiro, Derek M. Erion, Xiao Hui Liao, Gary J. Grover, Paul Webb, Kevin J. Phillips, Roy E. Weiss, Jonathan S...> ;American Journal of Physiology. Endocrinology and Metabolism. 2013 Jul 1
• Distinct ligand-dependent and independent modes of thyroid hormone receptor (TR)/PGC-1? interaction.
  Yuan, C.,Nguyen, P.,Baxter, J. D.,Webb, P.> ;J Steroid Biochem Mol Biol. 2013 Jan
• Research Resource: The Estrogen Receptor ? Cistrome Defined by DamIP.
  Xiao, R., Sun, D., Ayers, S., Xi, Y., Li, W., Baxter, J. D., Moore, D. D.> ;Mol Endocrinol. 2012 Feb
• Structural basis of coactivation of liver receptor homolog-1 by ?-catenin.
  Yumoto, F., Nguyen, P., Sablin, E. P., Baxter, J. D., Webb, P., Fletterick, R. J.> ;Proc Natl Acad Sci U S A. 2012 Jan 3
• Identical gene regulation patterns of T3 and selective thyroid hormone receptor modulator GC-1.
  Yuan, C., Lin, J. Z., Sieglaff, D. H., Ayers, S. D., Denoto-Reynolds, F., Baxter, J. D., Webb, P.> ;Endocrinology. 2012 Jan
• A peroxisome proliferator-activated receptor gamma (PPARgamma)/PPARgamma coactivator 1beta autoregulatory loop in adipocyte mitochondrial function.
  Deng, T., Sieglaff, D. H., Zhang, A., Lyon, C. J., Ayers, S. D., Cvoro, A., Gupte, A. A., Xia, X., Baxter, J. D., Webb, P., Hsueh, W. A.> ;J Biol Chem. 2011 Sep 2
• Resumption of HIV replication is associated with monocyte/macrophage derived cytokine and chemokine changes: results from a large international clinical trial.
  Cozzi-Lepri, A., French, M. A., Baxter, J., Okhuysen, P., Plana, M., Neuhaus, J., Landay, A.> ;AIDS. 2011 Jun 1
• Epidermal growth factor receptor (EGFR) is overexpressed in high-grade dysplasia and adenocarcinoma of the esophagus and may represent a biomarker of histological prog...
  Cronin, J., McAdam, E., Danikas, A., Tselepis, C., Griffiths, P., Baxter, J., Thomas, L., Manson, J., Jenkins, G.> ;Am J Gastroenterol. 2011 Jan
• Differences in reversion of resistance mutations to wild-type under structured treatment interruption and related increase in replication capacity.
  Paquet, A. C., Baxter, J., Weidler, J., Lie, Y., Lawrence, J., Kim, R., Bates, M., Coakley, E., Chappey, C.> ;PLoS One. 2011
• Estrogenic plant extracts reverse weight gain and fat accumulation without causing mammary gland or uterine proliferation.
  Saunier, E. F., Vivar, O. I., Rubenstein, A., Zhao, X., Olshansky, M., Baggett, S., Staub, R. E., Tagliaferri, M., Cohen, I., Speed, T. P., Baxter, J. D., Leitman, D. C.> ;PLoS One. 2011
• Rosiglitazone attenuates age- and diet-associated nonalcoholic steatohepatitis in male low-density lipoprotein receptor knockout mice.
  Gupte, A. A., Liu, J. Z., Ren, Y., Minze, L. J., Wiles, J. R., Collins, A. R., Lyon, C. J., Pratico, D., Finegold, M. J., Wong, S. T., Webb, P., Baxter, J. D., Moore, ...> ;Hepatology. 2010 Dec
• Improving the prediction of virological response to tipranavir: the development and validation of a tipranavir-weighted mutation score.
  Schapiro, J. M., Scherer, J., Boucher, C. A., Baxter, J. D., Tilke, C., Perno, C. F., Maggiolo, F., Santoro, M. M., Hall, D. B.> ;Antivir Ther (Lond). 2010
• Susceptibility of HIV-1 to tipranavir and other antiretroviral agents in treatment-experienced patients: The UTILIZE Study.
  Baxter, J. D., Bhatti, L., Coakley, E., Bartczak, J., McDonough, M., Vinisko, R., Piliero, P. J.> ;Curr HIV Res. 2010 Jun
• Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia.
  Ladenson, P. W., Kristensen, J. D., Ridgway, E. C., Olsson, A. G., Carlsson, B., Klein, I., Baxter, J. D., Angelin, B.> ;N Engl J Med. 2010 Mar 11
• Gaining ligand selectivity in thyroid hormone receptors via entropy.
  Martínez, L., Nascimento, A. S., Nunes, F. M., Phillips, K., Aparicio, R., Dias, S. M., Figueira, A. C., Lin, J. H., Nguyen, P., Apriletti, J. W., Neves, F. A., Baxter...> ;Proc Natl Acad Sci U S A. 2009 Dec 08
• Identification of CCR4 and other essential thyroid hormone receptor co-activators by modified yeast synthetic genetic array analysis.
  Govindan, M., Meng, X., Denis, C. L., Webb, P., Baxter, J. D., Walfish, P. G.> ;Proc Natl Acad Sci U S A. 2009 Nov 24
• Differential effects of TR ligands on hormone dissociation rates: evidence for multiple ligand entry/exit pathways.
  Cunha Lima, S. T., Nguyen, N. H., Togashi, M., Apriletti, J. W., Nguyen, P., Polikarpov, I., Scanlan, T. S., Baxter, J. D., Webb, P.> ;J Steroid Biochem Mol Biol. 2009 Nov 01
• Thyroid hormone mimetics: potential applications in atherosclerosis, obesity and type 2 diabetes.
  Baxter, J. D., Webb, P.> ;Nat Rev Drug Discov. 2009 Apr
• Molecular basis for dimer formation of TRbeta variant D355R.
  Jouravel, N., Sablin, E., Togashi, M., Baxter, J. D., Webb, P., Fletterick, R. J.> ;Proteins. 2009 Apr 01
• Low-abundance drug-resistant viral variants in chronically HIV-infected, antiretroviral treatment-naive patients significantly impact treatment outcomes.
  Simen, B. B., Simons, J. F., Hullsiek, K. H., Novak, R. M., Macarthur, R. D., Baxter, J. D., Huang, C., Lubeski, C., Turenchalk, G. S., Braverman, M. S., Desany, B., R...> ;J Infect Dis. 2009 Mar 01
• Complex actions of thyroid hormone receptor antagonist NH-3 on gene promoters in different cell lines.
  Shah, V., Nguyen, P., Nguyen, N. H., Togashi, M., Scanlan, T. S., Baxter, J. D., Webb, P.> ;Mol Cell Endocrinol. 2008 Dec 16
• Viral resuppression and detection of drug resistance following interruption of a suppressive non-nucleoside reverse transcriptase inhibitor-based regimen.
  Fox, Z., Phillips, A., Cohen, C., Neuhaus, J., Baxter, J., Emery, S., Hirschel, B., Hullsiek, K. H., Stephan, C., Lundgren, J.> ;AIDS. 2008 Nov 12
• Anti-obesity, anti-diabetic, and lipid lowering effects of the thyroid receptor beta subtype selective agonist KB-141.
  Bryzgalova, G., Effendic, S., Khan, A., Rehnmark, S., Barbounis, P., Boulet, J., Dong, G., Singh, R., Shapses, S., Malm, J., Webb, P., Baxter, J. D., Grover, G. J.> ;J Steroid Biochem Mol Biol. 2008 Sep
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