JohnCleatorMD

PubMed

• Polymorphisms and Clinical Outcomes Following Percutaneous Coronary Intervention (PCI) in the Million Veterans Program.
  Catherine Chanfreau-Coffinier, Kevin A Friede, Mary E Plomondon, Kyung Min Lee, Zhenyu Lu, Julie A Lynch, Scott L DuVall, Jason L Vassy, Stephen W Waldo, John H Cleato...> ;Medrxiv. 2023 Oct 26
• 2 citations
  Neuregulin (NRG-1β) Is Pro-Myogenic and Anti-Cachectic in Respiratory Muscles of Post-Myocardial Infarcted Swine.
  Cristi L Galindo, Van Thuan Nguyen, Braxton Hill, Ethan Easterday, John H Cleator, Douglas B Sawyer> ;Biology. 2022 Apr 29
• 53 citations
  Pharmacogenomic polygenic response score predicts ischaemic events and cardiovascular mortality in clopidogrel-treated patients
  Joshua P. Lewis, Joshua D. Backman, Jean-Luc Reny, Thomas O. Bergmeijer, Braxton D. Mitchell, Marylyn D. Ritchie, Jean-Pierre Déry, Ruth E. Pakyz, Li Gong, Kathleen A....> ;European Heart Journal. Cardiovascular Pharmacotherapy. 2020 Jul 1
• 25 citations
  Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmaco...
  Shefali S. Verma, Thomas O. Bergmeijer, Li Gong, Jean-Luc Reny, Joshua P. Lewis, Braxton D. Mitchell, Dimitrios Alexopoulos, Daniel Aradi, Russ B. Altman, Kevin P. Bli...> ;Clinical Pharmacology and Therapeutics. 2020 May 30
• 20 citations
  Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel P...
  Thomas O. Bergmeijer, Jean-Luc Reny, Ruth E. Pakyz, Li Gong, Joshua P. Lewis, Eun Young Kim, Daniel Aradi, Israel Fernandez-Cadenas, Richard B. Horenstein, Ming Ta Mic...> ;American Heart Journal. 2017 Dec 1
• The N54-αs Mutant Has Decreased Affinity for βγ and Suggests a Mechanism for Coupling Heterotrimeric G Protein Nucleotide Exchange with Subunit Dissociation.
  John H. Cleator, Christopher A. Wells, Jane Dingus, David T. Kurtz, John D. Hildebrandt> ;The Journal of Pharmacology and Experimental Therapeutics. 2018 Jan 1
• 3 citations
  Species-specific effects of neuregulin-1β (cimaglermin alfa) on glucose handling in animal models and humans with heart failure.
  Zhihong Huang, Douglas B. Sawyer, Erika L. Troy, Corissa McEwen, John H. Cleator, Abigail Murphy, Anthony O. Caggiano, Andrew Eisen, Tom J. Parry> ;Toxicology and Applied Pharmacology. 2017 Oct 1
• 3 citations
  A comparative study of different methods for automatic identification of clopidogrel-induced bleedings in electronic health records.
  Hee-Jin Lee, Min Jiang, Yonghui Wu, Christian M. Shaffer, John H. Cleator, Eitan A. Friedman, Joshua P. Lewis, Dan M. Roden, Josh C. Denny, Hua Xu> ;AMIA Joint Summits on Translational Science Proceedings. AMIA Joint Summits on Translational Science. 2017 Jul 26
• 43 citations
  Physician response to implementation of genotype-tailored antiplatelet therapy
  Josh F. Peterson, Julie R. Field, Kim M. Unertl, Jonathan S. Schildcrout, Daniel C. Johnson, Yaping Shi, Ioana Danciu, John H. Cleator, Jill M. Pulley, John A. McPhers...> ;Clinical Pharmacology and Therapeutics. 2016 Jul 1
• 6 citations
  Evaluation of the F2R IVS-14A/T PAR1 polymorphism with subsequent cardiovascular events and bleeding in patients who have undergone percutaneous coronary intervention.
  Eitan A. Friedman, Luisa Texeira, Jessica T. Delaney, Peter Weeke, Donald R Lynch, Ehab S. Kasasbeh, Yanna Song, Frank E. Harrell, Josh C. Denny, Heidi E. Hamm, Dan M....> ;Journal of Thrombosis and Thrombolysis. 2016 May 1
• 63 citations
  Anti-Remodeling and Anti-Fibrotic Effects of the Neuregulin-1β Glial Growth Factor 2 in a Large Animal Model of Heart Failure
  Cristi L. Galindo, Ehab Kasasbeh, Abigail Murphy, Sergey Ryzhov, Sean Lenihan, Farhaan A. Ahmad, Philip R. Williams, Amy H. Nunnally, Jamie Adcock, Yanna Song, Frank E...> ;Journal of the American Heart Association. 2014 Oct 24
• 5 citations
  Racial Differences in Resistance to P2Y12 Receptor Antagonists in Type 2 Diabetic Subjects
  John H. Cleator, Matthew T. Duvernay, Michael Holinstat, Nancy E. Colowick, Willie J. Hudson, Yanna Song, Frank E. Harrell, Heidi E. Hamm> ;The Journal of Pharmacology and Experimental Therapeutics. 2014 Oct 1
• 4 citations
  Dichotomous effects of exposure to bivalirudin in patients undergoing percutaneous coronary intervention on protease-activated receptor-mediated platelet activation.
  Michael Holinstat, Nancy E. Colowick, Willie J. Hudson, Dana L. Blakemore, Qingxia Chen, Heidi E. Hamm, John H. Cleator> ;Journal of Thrombosis and Thrombolysis. 2013 Feb 1
• 6 citations
  Learning curve in transradial cardiac catheterization: procedure-related parameters stratified by operators' transradial volume.
  Ehab S. Kasasbeh, Parvez B, Huang Rl, Hasselblad Mm, Glazer, Joseph Salloum, John H. Cleator, David Zhao> ;The Journal of Invasive Cardiology. 2012 Nov 1
• 77 citations
  Predicting clopidogrel response using DNA samples linked to an electronic health record.
  Jessica T. Delaney, Andrea H. Ramirez, Erica Bowton, Jill M. Pulley, Melissa A. Basford, Jonathan S. Schildcrout, Yaping Shi, Robert M. Zink, Matthew T. Oetjens, Hua X...> ;Clinical Pharmacology and Therapeutics. 2012 Feb 1
• 23 citations
  Identification of a region in G protein γ subunits conserved across species but hypervariable among subunit isoforms
  Lana A. Cook, Kevin L. Schey, John H. Cleator, Michael D. Wilcox, Jane Dingus, John D. Hildebrandt> ;Protein Science. 2009 Apr 8
• Routine Intraoperative Completion Angiography After Coronary Artery Bypass Grafting and 1-Stop Hybrid Revascularization Results from a Fully Integrated Hybrid Catheter...
  Joseph L Fredi, Mias Pretorius, Jorge M Balaguer, John H Cleator, Robert N Piana, David X Zhao, Konstantinos D Boudoulas, David A Slosky, James P Greelish, Robert J De...> ;Elsevier. 2009 Jan 20
• 4 citations
  Clinical Implications of the Contrasting Effects of In Vivo Thrombin Receptor Activation (Protease-Activated Receptor Type 1) on the Human Vasculature⁎
  John H. Cleator, Douglas E. Vaughan> ;Journal of the American College of Cardiology. 2008 May 6
• 89 citations
  PAR4, but Not PAR1, Signals Human Platelet Aggregation via Ca2+ Mobilization and Synergistic P2Y12 Receptor Activation
  Michael Holinstat, Bryan Voss, Matthew L. Bilodeau, Joseph N. McLaughlin, John H. Cleator, Heidi E. Hamm> ;The Journal of Biological Chemistry. 2006 Sep 8
• 78 citations
  Differential regulation of endothelial exocytosis of P-selectin and von Willebrand factor by protease-activated receptors and cAMP.
  John H. Cleator, Wen Qin Zhu, Douglas E. Vaughan, Heidi E. Hamm> ;Blood. 2006 Apr 1
• 37 citations
  G Protein betagamma dimer formation: Gbeta and Ggamma differentially determine efficiency of in vitro dimer formation.
  Jane Dingus, Christopher A. Wells, Lia H. Campbell, John H. Cleator, Kathryn Robinson, John D. Hildebrandt> ;Biochemistry. 2005 Aug 9
• 47 citations
  Thrombin Modulates the Expression of a Set of Genes Including Thrombospondin-1 in Human Microvascular Endothelial Cells
  Joseph N. McLaughlin, Maria Rosa Mazzoni, John H. Cleator, Laurie R. Earls, Ana Luisa Perdigoto, Joshua D. Brooks, James A.S. Muldowney, Douglas E. Vaughan, Heidi E. Hamm> ;The Journal of Biological Chemistry. 2005 Jun 10
• 12 citations
  A Dominant Negative Gαs Mutant That Prevents Thyroid-stimulating Hormone Receptor Activation of cAMP Production and Inositol 1,4,5-Trisphosphate Turnover COMPETITION B...
  John H. Cleator, Roneka R. Ravenell, David T. Kurtz, John D. Hildebrandt> ;The Journal of Biological Chemistry. 2004 Aug 27
• 17 citations
  The N54 mutant of Gαs has a conditional dominant negative phenotype which suppresses hormone-stimulated but not basal cAMP levels
  John H. Cleator, Nitin D. Mehta, David T. Kurtz, John D. Hildebrandt> ;FEBS Letters. 1999 Jan 29
• Effects of peripheral administration of synthetic human glucose-dependent insulinotropic peptide (GIP) on energy expenditure and subjective appetite sensations in heal...
  Daousi, C., Wilding, J. P., Aditya, S., Durham, B. H., Cleator, J., Pinkney, J. H., Ranganath, L. R.> ;Clin Endocrinol (Oxf). 2009 Aug 01
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