JohnW.DeSimoneMD

PubMed

• 34 citations
  Activation of the umami taste receptor (T1R1/T1R3) initiates the peristaltic reflex and pellet propulsion in the distal colon
  Derek M. Kendig, Norman Hurst, Zachary L. Bradley, Sunila Mahavadi, John F. Kuemmerle, Vijay Lyall, John A. DeSimone, Karnam S. Murthy, John R. Grider> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2014 Dec 1
• TRPM5-dependent Amiloride- and Benzamil-insensitive NaCl Chorda Tympani Taste Nerve Response.
  Ren, Z.,Rhyu, M. R.,Phan, T. H.,Mummalaneni, S.,Murthy, K. S.,Grider, J. R.,Desimone, J. A.,Lyall, V.> ;Am. J. Physiol. Gastrointest. Liver Physiol.. 2013 Jul 1
• N-geranyl cyclopropyl-carboximide modulates salty and umami taste in humans and animal models.
  Dewis, M. L.,Phan, T. H.,Ren, Z.,Meng, X.,Cui, M.,Mummalaneni, S.,Rhyu, M. R.,Desimone, J. A.,Lyall, V.> ;J Neurophysiol. 2013 Feb
• Sodium in the food supply: challenges and opportunities.
  DeSimone, J. A.,Beauchamp, G. K.,Drewnowski, A.,Johnson, G. H.> ;Nutr Rev. 2013 Jan
• Strain differences in the neural, behavioral, and molecular correlates of sweet and salty taste in naive, ethanol- and sucrose-exposed P and NP rats.
  Coleman, J., Williams, A., Phan, T. H., Mummalaneni, S., Melone, P., Ren, Z., Zhou, H., Mahavadi, S., Murthy, K. S., Katsumata, T., DeSimone, J. A., Lyall, V.> ;J Neurophysiol. 2011 Nov
• Involvement of NADPH-dependent and cAMP-PKA sensitive H+ channels in the chorda tympani nerve responses to strong acids.
  DeSimone, J. A., Phan, T. H., Heck, G. L., Ren, Z., Coleman, J., Mummalaneni, S., Melone, P., Lyall, V.> ;Chem Senses. 2011 May
• The K+-H+ exchanger, nigericin, modulates taste cell pH and chorda tympani taste nerve responses to acidic stimuli.
  Sturz, G. R., Phan, T. H., Mummalaneni, S., Ren, Z., DeSimone, J. A., Lyall, V.> ;Chem Senses. 2011 May
• Regulation of the putative TRPV1t salt taste receptor by phosphatidylinositol 4,5-bisphosphate.
  Lyall, V., Phan, T. H., Ren, Z., Mummalaneni, S., Melone, P., Mahavadi, S., Murthy, K. S., DeSimone, J. A.> ;J Neurophysiol. 2010 Mar
• Regulation of the benzamil-insensitive salt taste receptor by intracellular Ca2+, protein kinase C, and calcineurin.
  Lyall, V., Phan, T. H., Mummalaneni, S., Melone, P., Mahavadi, S., Murthy, K. S., DeSimone, J. A.> ;J Neurophysiol. 2009 Sep 01
• Nicotine activates TRPM5-dependent and independent taste pathways.
  Oliveira-Maia, A. J., Stapleton-Kotloski, J. R., Lyall, V., Phan, T. H., Mummalaneni, S., Melone, P., Desimone, J. A., Nicolelis, M. A., Simon, S. A.> ;Proc Natl Acad Sci U S A. 2009 Feb 03
• Effect of Maillard reacted peptides on human salt taste and the amiloride-insensitive salt taste receptor (TRPV1t).
  Katsumata, T., Nakakuki, H., Tokunaga, C., Fujii, N., Egi, M., Phan, T. H., Mummalaneni, S., DeSimone, J. A., Lyall, V.> ;Chem Senses. 2008 Sep
• Effect of nicotine on chorda tympani responses to salty and sour stimuli.
  Lyall, V., Phan, T. H., Mummalaneni, S., Mansouri, M., Heck, G. L., Kobal, G., DeSimone, J. A.> ;J Neurophysiol. 2007 Sep
• A psychophysical and electrophysiological analysis of salt taste in Trpv1 null mice.
  Treesukosol, Y., Lyall, V., Heck, G. L., DeSimone, J. A., Spector, A. C.> ;Am J Physiol Regul Integr Comp Physiol. 2007 May
• Taste receptors in the gastrointestinal tract III. Salty and sour taste: sensing of sodium and protons by the tongue.
  DeSimone, J. A., Lyall, V.> ;Am J Physiol Gastrointest Liver Physiol. 2006 Dec
• Intracellular pH modulates taste receptor cell volume and the phasic part of the chorda tympani response to acids.
  Lyall, V., Pasley, H., Phan, T. H., Mummalaneni, S., Heck, G. L., Vinnikova, A. K., DeSimone, J. A.> ;J Gen Physiol. 2006 Jan
• Ethanol modulates the VR-1 variant amiloride-insensitive salt taste receptor. II. Effect on chorda tympani salt responses.
  Lyall, V., Heck, G. L., Phan, T. H., Mummalaneni, S., Malik, S. A., Vinnikova, A. K., Desimone, J. A.> ;J Gen Physiol. 2005 Jun
• Ethanol modulates the VR-1 variant amiloride-insensitive salt taste receptor. I. Effect on TRC volume and Na+ flux.
  Lyall, V., Heck, G. L., Phan, T. H., Mummalaneni, S., Malik, S. A., Vinnikova, A. K., DeSimone, J. A.> ;J Gen Physiol. 2005 Jun
• A novel vanilloid receptor-1 (VR-1) variant mammalian salt taste receptor.
  Lyall, V., Heck, G. L., Vinnikova, A. K., Ghosh, S., Phan, T. H., Desimone, J. A.> ;Chem Senses. 2005 Jan
• The mammalian amiloride-insensitive non-specific salt taste receptor is a vanilloid receptor-1 variant.
  Lyall, V., Heck, G. L., Vinnikova, A. K., Ghosh, S., Phan, T. H., Alam, R. I., Russell, O. F., Malik, S. A., Bigbee, J. W., DeSimone, J. A.> ;J Physiol (Lond). 2004 Jul 1
• Basolateral Na+-H+ exchanger-1 in rat taste receptor cells is involved in neural adaptation to acidic stimuli.
  Lyall, V., Alam, R. I., Malik, S. A., Phan, T. H., Vinnikova, A. K., Heck, G. L., DeSimone, J. A.> ;J Physiol (Lond). 2004 Apr 1
• Na+-H+ exchange activity in taste receptor cells.
  Vinnikova, A. K., Alam, R. I., Malik, S. A., Ereso, G. L., Feldman, G. M., McCarty, J. M., Knepper, M. A., Heck, G. L., DeSimone, J. A., Lyall, V.> ;J Neurophysiol. 2004 Mar
• Salt-evoked lingual surface potential in humans.
  Feldman, G. M., Mogyorosi, A., Heck, G. L., DeSimone, J. A., Santos, C. R., Clary, R. A., Lyall, V.> ;J Neurophysiol. 2003 Sep
• Modulation of rat chorda tympani NaCl responses and intracellular Na+ activity in polarized taste receptor cells by pH.
  Lyall, V., Alam, R. I., Phan, T. H., Russell, O. F., Malik, S. A., Heck, G. L., DeSimone, J. A.> ;J Gen Physiol. 2002 Dec
• Excitation and adaptation in the detection of hydrogen ions by taste receptor cells: a role for cAMP and Ca(2+).
  Lyall, V., Alam, R. I., Phan, T. H., Phan, D. Q., Heck, G. L., DeSimone, J. A.> ;J Neurophysiol. 2002 Jan
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