JohnEEdwardsMD

PubMed

• NDV-3A vaccination prevents C. albicans colonization of jugular vein catheters in mice.
  Alqarihi, A.,Singh, S.,Edwards, J. E.,Ibrahim, A. S.,Uppuluri, P.> ;Sci Rep. 2019 Apr 19
• PCR-based approach targeting Mucorales specific gene family for the diagnosis of mucormycosis.
  Baldin, C.,Soliman, SSM.,Jeon, H. H.,Alkhazraji, S.,Gebremariam, T.,Gu, Y.,Bruno, V. M.,Cornely, O. A.,Leather, H. L.,Sugrue, M. W.,Wingard, J. R.,Stevens, D. A.,Edwar...> ;J. Clin. Microbiol.. 2018 Aug 03
• Human Anti-Als3p Antibodies Are Surrogate Markers of NDV-3A Vaccine Efficacy Against Recurrent Vulvovaginal Candidiasis.
  Uppuluri, P.,Singh, S.,Alqarihi, A.,Schmidt, C. S.,Hennessey, J. P.,Yeaman, M. R.,Filler, S. G.,Edwards, J. E.,Ibrahim, A. S.> ;Front Immunol. 2018 Jul 03
• Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcu...
  Chan, L. C.,Chaili, S.,Filler, S. G.,Barr, K.,Wang, H.,Kupferwasser, D.,Edwards, J. E.,Xiong, Y. Q.,Ibrahim, A. S.,Miller, L. S.,Schmidt, C. S.,Hennessey, J. P.,Yeaman...> ;Infect. Immun.. 2015 Sep 10
• Mechanisms of NDV-3 vaccine efficacy in MRSA skin versus invasive infection.
  Yeaman, M. R.,Filler, S. G.,Chaili, S.,Barr, K.,Wang, H.,Kupferwasser, D.,Hennessey, J. P.,Fu, Y.,Schmidt, C. S.,Edwards, J. E.,Xiong, Y. Q.,Ibrahim, A. S.> ;Proc. Natl. Acad. Sci. U.S.A.. 2014 Dec 10
• Isavuconazole Therapy Protects Immunosuppressed Mice from Mucormycosis.
  Luo, G.,Gebremariam, T.,Lee, H.,Edwards, J. E.,Kovanda, L.,Ibrahim, A. S.> ;Antimicrob. Agents Chemother.. 2014 Feb 05
• NDV-3 protects mice from vulvovaginal candidiasis through T- and B-cell immune response.
  Ibrahim, A. S.,Luo, G.,Gebremariam, T.,Lee, H.,Schmidt, C. S.,Hennessey, J. P.,French, S. W.,Yeaman, M. R.,Filler, S. G.,Edwards, J. E.> ;Vaccine. 2013 Sep 21
• Investigation of the Function of Candida albicans Als3 by Heterologous Expression in Candida glabrata.
  Fu, Y.,Phan, Q. T.,Luo, G.,Solis, N. V.,Liu, Y.,Cormack, B. P.,Edwards, J. E.,Ibrahim, A. S.,Filler, S. G.> ;Infect. Immun.. 2013 Jul
• Combination therapy of murine mucormycosis or aspergillosis with iron chelation, polyenes, and echinocandins.
  Ibrahim, A.S., Gebremariam, T., Luo, G., Fu, Y., French, S.W., Edwards, J.E., Spellberg, B.> ;Antimicrob Agents Chemother. 2011 Apr
• Active and Passive Immunization with rHyr1p-N Protects Mice against Hematogenously Disseminated Candidiasis.
  Luo, G., Ibrahim, A.S., French, S.W., Edwards, J.E., Fu, Y.> ;PLoS One. 2011
• Should the guidelines for management of central venous catheters in patients with candidemia be changed now?
  Brass, E.P., Edwards, J.E.> ;Clin Infect Dis. 2010 Aug 1
• The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice.
  Liu, M., Spellberg, B., Phan, Q.T., Fu, Y., Fu, Y., Lee, A.S., Edwards, J.E., Filler, S.G., Ibrahim, A.S.> ;J Clin Invest. 2010 Jun
• Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice.
  Lin, L., Ibrahim, A.S., Xu, X., Farber, J.M., Avanesian, V., Baquir, B., Fu, Y., French, S.W., Edwards, J.E., Spellberg, B.> ;PLoS Pathog. 2009 Dec
• Posaconazole mono- or combination therapy for treatment of murine zygomycosis.
  Ibrahim, A.S., Gebremariam, T., Schwartz, J.A., Edwards, J.E., Spellberg, B.> ;Antimicrob Agents Chemother. 2009-02-01
• Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America.
  Boucher, H.W., Talbot, G.H., Bradley, J.S., Edwards, J.E., Gilbert, D., Rice, L.B., Scheld, M., Spellberg, B., Bartlett, J.> ;Clin Infect Dis. 2009-01-01
• the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin.
  Almeida, R.S., Brunke, S., Albrecht, A., Thewes, S., Laue, M., Edwards, J.E., Filler, S.G., Hube, B.> ;PLoS Pathog. 2008-11-01
• The antifungal vaccine derived from the recombinant N terminus of Als3p protects mice against the bacterium Staphylococcus aureus.
  Spellberg, B., Ibrahim, A.S., Yeaman, M.R., Lin, L., Fu, Y., Avanesian, V., Bayer, A.S., Filler, S.G., Lipke, P., Otoo, H., Edwards, J.E.> ;Infect Immun. 2008 Oct
• Bacterial endosymbiosis is widely present among zygomycetes but does not contribute to the pathogenesis of mucormycosis.
  Ibrahim, A.S., Gebremariam, T., Liu, M., Chamilos, G., Kontoyiannis, D., Mink, R., Kwon-Chung, K.J., Fu, Y., Skory, C.D., Edwards, J.E., Spellberg, B.> ;J Infect Dis. 2008 Oct 1
• SSD1 is integral to host defense peptide resistance in Candida albicans.
  Gank, K.D., Yeaman, M.R., Kojima, S., Yount, N.Y., Park, H., Edwards, J.E., Filler, S.G., Fu, Y.> ;Eukaryot Cell. 2008 Aug
• Empirical fluconazole versus placebo for intensive care unit patients: a randomized trial.
  Schuster, M.G., Edwards, J.E., Sobel, J.D., Darouiche, R.O., Karchmer, A.W., Hadley, S., Slotman, G., Panzer, H., Biswas, P., Rex, J.H.> ;Ann Intern Med. 2008 Jul 15
• Combination echinocandin-polyene treatment of murine mucormycosis.
  Ibrahim, A.S., Gebremariam, T., Fu, Y., Edwards, J.E., Spellberg, B.> ;Antimicrob Agents Chemother. 2008 Apr
• Comparison of lipid amphotericin B preparations in treating murine zygomycosis.
  Ibrahim, A.S., Gebremariam, T., Husseiny, M.I., Stevens, D.A., Fu, Y., Edwards, J.E., Spellberg, B.> ;Antimicrob Agents Chemother. 2008 Apr
• Antibody titer threshold predicts anti-candidal vaccine efficacy even though the mechanism of protection is induction of cell-mediated immunity.
  Spellberg, B., Ibrahim, A.S., Lin, L., Avanesian, V., Fu, Y., Lipke, P., Otoo, H., Ho, T., Edwards, J.E.> ;J Infect Dis. 2008 Apr 1
• Gene overexpression/suppression analysis of candidate virulence factors of Candida albicans.
  Fu, Y., Luo, G., Spellberg, B.J., Edwards, J.E., Ibrahim, A.S.> ;Eukaryot Cell. 2008 Mar
• Considerable differences in vaccine immunogenicities and efficacies related to the diluent used for aluminum hydroxide adjuvant.
  Lin, L., Ibrahim, A.S., Avanesian, V., Edwards, J.E., Fu, Y., Baquir, B., Taub, R., Spellberg, B.> ;Clin Vaccine Immunol. 2008 Mar
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