JohnW.HollingsworthIIMD

Pulmonology • Fort Worth, TX

Critical Care Medicine, Pleural Disease

Adjunct Professor of Medicine, Ohio State University

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Office
1201 Fairmount Ave
Fort Worth, TX 76104
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Education & Training

Duke University HospitalFellowship, Pulmonary Disease and Critical Care Medicine, 2000 - 2003
University of Texas Medical Branch HospitalsResidency, Internal Medicine, 1996 - 1999
University of Texas Medical Branch School of MedicineClass of 1996

Certifications & Licensure

TX State Medical License 1998 - 2025
NC State Medical License 2000 - 2019
OH State Medical License 2014 - 2016
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Awards, Honors, & Recognition

Fellow American College of Chest Physicians, 2016
Elected Member The American Society for Clinical Investigation, 2012

Publications & Presentations

PubMed

3 citations
Wood smoke particle exposure in mice reduces the severity of influenza infection.
Aaron Vose, Matthew McCravy, Anastasiya Birukova, Zhonghui Yang, John W. Hollingsworth, Loretta G. Que, Robert M. Tighe> ;Toxicology and Applied Pharmacology. 2021 Sep 1
5 citations
Case series of acute appendicitis association with SARS-CoV-2 infection.
Charlsea Prichard, Matthew Canning, Kindra McWilliam-Ross, John Birbari, William Parker, Lori Tabor Wasson, John W. Hollingsworth> ;BMC Infectious Diseases. 2021 Feb 25
39 citations
TLR5 participates in the TLR4 receptor complex and promotes MyD88-dependent signaling in environmental lung injury.
Salik Hussain, Collin G. Johnson, Joseph Sciurba, Xianglin Meng, Vandy P. Stober, Caini Liu, Jaime M. Cyphert-Daly, Katarzyna Bulek, Wen Qian, Alma Solis, Yosuke Sakam...> ;Elife. 2020 Jan 28
Retraction notice to NAD(P)H:QUINONE OXIOREDUCTASE 1 PROTECTS LUNGS FROM OXIDANT-INDUCED EMPHYSEMA IN MICE [FRB 52/3 (2012) 705 - 715].
Erin N. Potts-Kant, Zhuowei Li, Robert M. Tighe, James Y. Lindsey, Benjamin W. Frush, W. Michael Foster, John W. Hollingsworth> ;Free Radical Biology & Medicine. 2017 Dec 1
1 citations
Comment on Expression of Concern: TLR4 Is Necessary for Hyaluronan-mediated Airway Hyperresponsiveness after Ozone Inhalation.
Stavros Garantziotis, John W. Hollingsworth> ;American Journal of Respiratory and Critical Care Medicine. 2017 Jul 14
17 citations
Biogas Stoves Reduce Firewood Use, Household Air Pollution, and Hospital Visits in Odisha, India.
Jessica Lewis, John W. Hollingsworth, Ryan Chartier, Ellen M. Cooper, William M. Foster, Genna Gomes, Peter S. Kussin, John J. MacInnis, Bijaya Kumar Padhi, Pinaki Pan...> ;Environmental Science & Technology. 2017 Jan 3
10 citations
Ozone primes alveolar macrophage-derived innate immunity in healthy human subjects.
Benjamin W. Frush, Zhuowei Li, Jane V. Stiles, Sarah F. Cotter, Scott Shofer, W. Michael Foster, John W. Hollingsworth, Robert M. Tighe> ;The Journal of Allergy and Clinical Immunology. 2016 Oct 1
12 citations
Erratum: Hyaluronan mediates ozone-induced airway hyperresponsiveness in mice (The Journal of Biological Chemistry (2009) 284 (11309-11317) DOI: 10.1074/jbc.A116.802400)
Stavros Garantziotis, Zhuowei Li, Erin N. Potts, Koji Kimata, Lisheng Zhuo, Daniel L. Morgan, Rashmin C. Savani, Paul W. Noble, W. Michael Foster, David A. Schwartz, J...> ;The Journal of Biological Chemistry. 2016 Sep 9
22 citations
Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling.
Miguel Pinilla-Vera, Zeyu Xiong, Yutong Zhao, Jing Zhao, Michael P. Donahoe, Suchitra Barge, William Horne, Jay K. Kolls, Bryan J. McVerry, Anastasiya Birukova, Robert...> ;Plos One. 2016 Jul 19
2 citations
Correction: Hyaluronan Fragments Contribute to the Ozone-Primed Immune Response to Lipopolysaccharide.
Zhuowei Li, Erin N. Potts, Claude A. Piantadosi, W. Michael Foster, John W. Hollingsworth> ;Journal of Immunology. 2016 Mar 1
1 citations
Comment on Expression of Concern: c-Kit Is Essential for Alveolar Maintenance and Protection from Emphysema-like Disease in Mice.
John W. Hollingsworth, George D. Leikauf, James Y. Lindsey, Holger Schulz> ;American Journal of Respiratory and Critical Care Medicine. 2016 Mar 1
162 citations
Flow Cytometric Analysis of Myeloid Cells in Human Blood, Bronchoalveolar Lavage, and Lung Tissues.
Yen-Rei A. Yu, Danielle F. Hotten, Yuryi Malakhau, Ellen Volker, Andrew J. Ghio, Paul W. Noble, Monica Kraft, John W. Hollingsworth, Michael D. Gunn, Robert M. Tighe> ;American Journal of Respiratory Cell and Molecular Biology. 2016 Jan 1
21 citations
Genetic Variation in SP-A2 Leads to Differential Binding to Mycoplasma pneumoniae Membranes and Regulation of Host Responses
Julie G. Ledford, Dennis R. Voelker, Kenneth J. Addison, Ying Wang, Vinayak S. Nikam, Simone Degan, Pitachaimani Kandasamy, Sasipa Tanyaratsrisakul, Bernard M. Fischer...> ;Journal of Immunology. 2015 Jun 15
10 citations
Surfactant protein D attenuates sub-epithelial fibrosis in allergic airways disease through TGF-β
Hirohisa Ogawa, Julie G. Ledford, Sambuddho Mukherjee, Yoshinori Aono, Yasuhiko Nishioka, James J. Lee, Keisuke Izumi, John W. Hollingsworth> ;Respiratory Research. 2014 Nov 29
11 citations
Identification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A.
Matthew W. Foster, J. Will Thompson, Julie G. Ledford, Laura G. Dubois, John W. Hollingsworth, Dave Francisco, Sasipa Tanyaratsrisakul, Dennis R. Voelker, Monica Kraft...> ;Journal of Proteome Research. 2014 Aug 1
12 citations
Bronchial epithelial injury in the context of alloimmunity promotes lymphocytic bronchiolitis through hyaluronan expression.
Vandy P. Stober, Christopher Szczesniak, Quiana Childress, Rebecca L. Heise, Carl D. Bortner, John W. Hollingsworth, Isabel P. Neuringer, Scott M. Palmer, Stavros Gara...> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2014 Jun 1
29 citations
Conditional Knockout of the RNA-Binding Protein HuR in CD4 + T Cells Reveals a Gene Dosage Effect on Cytokine Production
Matthew M. Gubin, Patsharaporn Techasintana, Joseph D. Magee, Garrett M. Dahm, Robert Calaluce, Jennifer L. Martindale, Maryln S. Whitney, Craig L. Franklin, Cindy Bes...> ;Molecular Medicine. 2014 Mar 20
27 citations
High Intensive Care Unit Admission Rate for 2013–2014 Influenza Is Associated with a Low Rate of Vaccination
Jelena Catania, Loretta G. Que, Joseph A. Govert, John W. Hollingsworth, Cameron R. Wolfe> ;American Journal of Respiratory and Critical Care Medicine. 2014 Feb 14
6 citations
Stress: A Possible Link between Genetics, Epigenetics, and Childhood Asthma
Susan K. Murphy, John W. Hollingsworth> ;American Journal of Respiratory and Critical Care Medicine. 2013 Mar 26
18 citations
Genes of innate immunity and the biological response to inhaled ozone
Zhuowei Li, Robert M. Tighe, Feifei Feng, Julie G. Ledford, John W. Hollingsworth> ;Journal of Biochemical and Molecular Toxicology. 2013 Jan 1
58 citations
Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype.
Njira L Lugogo, John W. Hollingsworth, Druhan L. Howell, Loretta G. Que, Dave Francisco, Tony D. Church, Erin N. Potts-Kant, Jennifer L. Ingram, Ying Wang, Sin-Ho Jung...> ;American Journal of Respiratory and Critical Care Medicine. 2012 Dec 14
42 citations
An Official American Thoracic Society Workshop Report: Climate Change and Human Health
Kent E. Pinkerton, William N. Rom, Muge Akpinar-Elci, John R. Balmes, Hasan Bayram, Otto Brandli, John W. Hollingsworth, Patrick L. Kinney, Helene G. Margolis, William...> ;Proceedings of the American Thoracic Society. 2012 Dec 14
21 citations
Hyaluronan activation of the Nlrp3 inflammasome contributes to the development of airway hyperresponsiveness.
Feifei Feng, Zhuowei Li, Erin N. Potts-Kant, Yiming Wu, W. Michael Foster, Kristi L. Williams, John W. Hollingsworth> ;Environmental Health Perspectives. 2015 Jul 1
58 citations
Health benefits from large-scale ozone reduction in the United States.
Jesse D. Berman, Neal Fann, John W. Hollingsworth, Kent E. Pinkerton, William N. Rom, Anthony M. Szema, Patrick N. Breysse, Ronald H. White, Frank C. Curriero> ;Environmental Health Perspectives. 2012 Jul 18
26 citations
Surfactant Protein-A Suppresses Eosinophil-Mediated Killing of Mycoplasma pneumoniae in Allergic Lungs
Julie G. Ledford, Sambuddho Mukherjee, Michele M. Kislan, Julia L. Nugent, John W. Hollingsworth, Jo Rae Wright> ;Plos One. 2012 Feb 23
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