JohnJLetterioMD

PubMed

• 1 citations
  Overexpression of VEGF in the MOPC 315 Plasmacytoma Induces Tumor Immunity in Mice.
  Byung-Gyu Kim, Sung Hee Choi, John J Letterio, Jie-Young Song, Alex Y Huang> ;International Journal of Molecular Sciences. 2022 May 7
• 2 citations
  Smad4-deficient T cells promote colitis-associated colon canceran IFN-γ-dependent suppression of 15-hydroxyprostaglandin dehydrogenase.
  Sung Hee Choi, Alex Y Huang, John J Letterio, Byung-Gyu Kim> ;Frontiers in Immunology. 2022 Jan 1
• 1 citations
  O-Fucose and Fringe-modified NOTCH1 extracellular domain fragments as decoys to release niche-lodged hematopoietic progenitor cells
  Shuiliang Yu, Weihuan Wang, Marwah Albakri, Xiaoxing Yu, Gurnoor Majihail, Seunghwan Lim, Rachel K. LoPilato, Atsuko Ito, John J. Letterio, Robert S. Haltiwanger, Lan ...> ;Glycobiology. 2021 Jun 3
• 5 citations
  Loss of p27Kip1 leads to expansion of CD4+ effector memory T cells and accelerates colitis-associated colon cancer in mice with a T cell lineage restricted deletion of...
  Sung Hee Choi, Emily C. Barker, Kyle J Gerber, John J. Letterio, Byung-Gyu Kim> ;Oncoimmunology. 2020 Dec 3
• 2 citations
  Analyzing the Metabolic Phenotype of Bone Marrow-Derived Dendritic Cells by Assessing Their Oxygen Consumption and Extracellular Acidification.
  Hsi Ju Wei, John J. Letterio, Tej K. Pareek> ;Methods in Molecular Biology. 2020 Jan 1
• 11 citations
  Estimating the prevalence and risk of COVID-19 among international travelers and evacuees of Wuhan through modeling and case reports.
  George Luo, Michael L. McHenry, John J. Letterio> ;Plos One. 2020 Jun 23
• 10 citations
  Combination Therapy for Treating Advanced Drug-Resistant Acute Lymphoblastic Leukemia
  Yorleny Vicioso, Hermann Gram, Rose Beck, Abhishek Asthana, Keman Zhang, Derek Wong, John J. Letterio, Reshmi Parameswaran> ;Cancer Immunology Research. 2019 Jul 1
• 20 citations
  Nrf2-mediated metabolic reprogramming of tolerogenic dendritic cells is protective against aplastic anemia
  Hsi Ju Wei, Ashish Gupta, Wei Ming Kao, Omar Almudallal, John J. Letterio, Tej K. Pareek> ;Journal of Autoimmunity. 2018 Nov 1
• 7 citations
  Development and Functional Characterization of Murine Tolerogenic Dendritic Cells
  Hsi Ju Wei, John J. Letterio, Tej K. Pareek> ;Journal of Visualized Experiments. 2018 May 18
• 14 citations
  Potent suppression of both spontaneous and carcinogen-induced colitis-associated colorectal cancer in mice by dietary celastrol supplementation.
  Emily C. Barker, Byung-Gyu Kim, Ji Hee Yoon, Gregory P. Tochtrop, John J. Letterio, Sung Hee Choi> ;Carcinogenesis. 2018 Jan 12
• Response to "GHB concentration in breast milk of narcoleptic women treated with sodium oxybate. How important it is to be careful when interpreting values." (Letter to...
  Emily C. Barker, Michelle Puchowicz, John J. Letterio, Kristine Higgins, Katherine M. Sharkey> ;Sleep Medicine. 2017 Aug 24
• 16 citations
  A unique tolerizing dendritic cell phenotype induced by the synthetic triterpenoid CDDO-DFPA (RTA-408) is protective against EAE.
  Hsi Ju Wei, Tej K. Pareek, Qi Liu, John J. Letterio> ;Scientific Reports. 2017 Aug 29
• 8 citations
  GHB levels in breast milk of women with narcolepsy with cataplexy treated with sodium oxybate.
  Emily C. Barker, Michelle Puchowicz, John J. Letterio, Kristine Higgins, Katherine M. Sharkey> ;Sleep Medicine. 2017 Aug 1
• 12 citations
  Cyclin-dependent kinase 5 activity is required for allogeneic T-cell responses after hematopoietic cell transplantation in mice.
  David Askew, Tej K. Pareek, Saada Eid, Sudipto Ganguly, Megan Tyler, Alex Yee-Chen Huang, John J. Letterio, Kenneth R. Cooke> ;Blood. 2017 Jan 12
• 92 citations
  Myeloid-derived suppressor cells: The green light for myeloma immune escape
  Ehsan Malek, Marcos de Lima, John J. Letterio, Byung-Gyu Kim, James H. Finke, James J. Driscoll, Sergio Giralt> ;Blood Reviews. 2016 Sep 1
• 2 citations
  Development and Validation of a Small Animal Immobilizer and Positioning System for the Study of Delivery of Intracranial and Extracranial Radiotherapy Using the Gamma...
  Musaddiq J. Awan, Jennifer A. Dorth, Arvind Mani, Haksoo Kim, Y. Zheng, Mazen Mislmani, Scott M. Welford, Jiankui Yuan, Barry W. Wessels, Simon S. Lo, John J. Letterio...> ;Technology in Cancer Research & Treatment. 2017 Apr 1
• 228 citations
  Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity
  R. Dixon Dorand, Joseph Nthale, Jay Myers, Deborah S. Barkauskas, Stephanie Avril, Steven M. Chirieleison, Tej K. Pareek, Derek W. Abbott, Duncan Stearns, John J. Lett...> ;Science. 2016 Jul 22
• 13 citations
  The proinflammatory LTB4/BLT1 signal axis confers resistance to TGF-β1-induced growth inhibition by targeting Smad3 linker region.
  Woo Kwang Jeon, Jiyeon Choi, Seong Ji Park, Eun Ji Jo, Young K. Lee, Seunghwan Lim, Jae Hong Kim, John J. Letterio, Fang Liu, Seong-Jin Kim, Byung-Chul Kim> ;Oncotarget. 2015 Oct 19
• 39 citations
  Hepatic Stellate Cells Inhibit T Cells through Active TGF-β1 from a Cell Surface–Bound Latent TGF-β1/GARP Complex
  Yan Li, Byung-Gyu Kim, Shiguang Qian, John J. Letterio, John J. Fung, Lina Lu, Feng Lin> ;Journal of Immunology. 2015 Sep 15
• 24 citations
  Cyclin-dependent kinase 5 represses Foxp3 gene expression and Treg development through specific phosphorylation of Stat3 at Serine 727.
  Eric Lam, Sung Hee Choi, Tej K. Pareek, Byung-Gyu Kim, John J. Letterio> ;Molecular Immunology. 2015 Jul 19
• 17 citations
  Cdk5 controls IL-2 gene expression via repression of the mSin3a-HDAC complex
  Eric Lam, Tej K. Pareek, John J. Letterio> ;Cell Cycle. 2015 Mar 18
• 361 citations
  Alex's Lemonade stand foundation infant and childhood primary brain and central nervous system tumors diagnosed in the United States in 2007-2011
  Quinn T. Ostrom, Peter de Blank, Carol Kruchko, Claire M. Petersen, Peter Liao, Jonathan L. Finlay, Duncan Stearns, Johannes E. A. Wolff, Yingli Wolinsky, John J. Lett...> ;Neuro-Oncology. 2015 Jan 1
• 14 citations
  Triterpenoid inducers of Nrf2 signaling as potential therapeutic agents in sickle cell disease: a review.
  Amma Owusu-Ansah, Sung H ee Choi, Agne Petrosiute, John J. Letterio, Alex Yee-Chen Huang> ;Frontiers of Medicine. 2015 Mar 2
• 67 citations
  Amyloid-β precursor protein promotes cell proliferation and motility of advanced breast cancer
  Seunghwan Lim, Byoung Kwon Yoo, Hae-Suk Kim, Hannah Gilmore, Yong-Hun Lee, Hyun-Pil Lee, Seong-Jin Kim, John J. Letterio, Hyoung Gon Lee> ;BMC Cancer. 2014 Dec 10
• 40 citations
  Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis
  Sung Hee Choi, Byung-Gyu Kim, Janet Robinson, Steve Fink, Min Yan, Michael B. Sporn, Sanford D. Markowitz, John J. Letterio> ;The Journal of Clinical Investigation. 2014 Jun 2
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Abstracts/Posters

• Preclinical Studies and Phase I Trial of Vactosertib in Combination with Pomalidomide in Relapsed Multiple Myeloma: A Corticosteroid-Free Approach By Targeting TGF-_ S...
  John Letterio, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Lectures

• Vactosertib, a TGF-ß Receptor I Kinase/ALK5 Inhibitor, Diminishes Tumor Progression and Bone Disease in a Mouse Model of Multiple Myeloma and Overcomes Resistance to P... 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Preclinical Studies and a Phase I Trial of the TGF-β Receptor Inhibitor, Vactosertib (TEW-7197), in Combination with Pomalidomide in Patients with Multiple Myeloma Ref... 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018