JohnCMcCannMD

Oncology • Springfield, MA

Assistant Professor, Medicine, Tufts Medical Center

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Office
3350 Main St
Baystate Regl Cancer Program
Springfield, MA 01199
Phone+1 413-794-9338

Fax+1 413-794-9754
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Education & Training

Tufts Medical CenterFellowship, Hematology and Medical Oncology, 1992 - 1995
Tufts Medical CenterResidency, Internal Medicine, 1988 - 1991
University of Massachusetts Medical SchoolClass of 1988

Certifications & Licensure

MA State Medical License 1990 - 2025
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2011

Clinical Trials

Study of Pemetrexed and Gemcitabine for Patients With a New Diagnosis of Extensive-Stage Small Cell Lung Cancer Start of enrollment: 2005 Aug 01
Terminated
Phase 2
Cetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer Start of enrollment: 2005 Nov 01
Completed
Phase 3
Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-small Cell Lung Cancer That Was Removed By Surgery Start of enrollment: 2007 Jun 01
Active, not recruiting
Phase 3
Combination Chemotherapy and Cetuximab in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer Start of enrollment: 2006 Sep 15
Completed
Phase 2
Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Start of enrollment: 2008 Aug 08
Active, not recruiting
Phase 3
Bevacizumab or Pemetrexed Disodium Alone or In Combination After Induction Therapy in Treating Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer Start of enrollment: 2010 Oct 25
Completed
Phase 3
Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery Start of enrollment: 2011 May 25
Active, not recruiting
Phase 3
Study Comparing Combination of LGX818 Plus MEK162 Versus Vemurafenib and LGX818 Monotherapy in BRAF Mutant Melanoma Start of enrollment: 2013 Dec 13
Active, not recruiting
Phase 3
A Study of Abemaciclib (LY2835219) in Participants With Previously Treated KRAS Mutated Lung Cancer Start of enrollment: 2014 Oct 03
Active, not recruiting
Phase 3
A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma Start of enrollment: 2015 Nov 23
Recruiting
Phase 2, Phase 3
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Publications & Presentations

PubMed

38 citations
Pemetrexed, Bevacizumab, or the Combination As Maintenance Therapy for Advanced Nonsquamous Non–Small-Cell Lung Cancer: ECOG-ACRIN 5508
Suresh S. Ramalingam, Suzanne E. Dahlberg, Chandra P. Belani, Joel N. Saltzman, Nathan A. Pennell, Gopakumar S. Nambudiri, John McCann, Jerome D. Winegarden, Mohammed ...> ;Journal of Clinical Oncology. 2019 Jul 30
15 citations
A combination of mild hypothermia and sevoflurane affords long-term protection in a modified neonatal mouse model of cerebral hypoxia-ischemia.
Erica P. Lin, Lili Miles, Elizabeth A. Hughes, John McCann, Charles V. Vorhees, John J. McAuliffe, Andreas W. Loepke> ;Anesthesia and Analgesia. 2014 Nov 1
69 citations
Characterization and quantification of isoflurane-induced developmental apoptotic cell death in mouse cerebral cortex.
George K. Istaphanous, Christopher G. Ward, Xinyu Nan, Elizabeth A. Hughes, John McCann, John J. McAuliffe, Steve C. Danzer, Andreas W. Loepke> ;Anesthesia and Analgesia. 2013 Mar 4
196 citations
Comparison of the neuroapoptotic properties of equipotent anesthetic concentrations of desflurane, isoflurane, or sevoflurane in neonatal mice.
George K. Istaphanous, Jennifer Howard, Xinyu Nan, Elizabeth A. Hughes, John McCann, John J. McAuliffe, Steve C. Danzer, Andreas W. Loepke> ;Anesthesiology. 2011 Mar 1
77 citations
Cerebral oxygen saturation-time threshold for hypoxic-ischemic injury in piglets.
C. Dean Kurth, John McCann, Jun Wu, Lili Miles, Andreas W. Loepke> ;Anesthesia and Analgesia. 2009 Apr 1
194 citations
The effects of neonatal isoflurane exposure in mice on brain cell viability, adult behavior, learning, and memory.
Andreas W. Loepke, George K. Istaphanous, John J. McAuliffe, Lili Miles, Elizabeth A. Hughes, John McCann, Kathryn E. Harlow, C. Dean Kurth, Michael T. Williams, Charl...> ;Anesthesia and Analgesia. 2009 Jan 1
17 citations
Development and validation of a multiwavelength spatial domain near-infrared oximeter to detect cerebral hypoxia-ischemia.
Lindsey A. Nelson, John McCann, Andres W. Loepke, Jun Wu, Baruch Ben Dor, C. Dean Kurth> ;Journal of Biomedical Optics. 2006 Nov 1
91 citations
The physiologic effects of isoflurane anesthesia in neonatal mice.
Andreas W. Loepke, John McCann, C. Dean Kurth, John J. McAuliffe> ;Anesthesia and Analgesia. 2006 Jan 1
11 citations
Injury pattern of the neonatal brain after hypothermic low-flow cardiopulmonary bypass in a piglet model.
Andreas W. Loepke, Jeffrey A. Golden, John McCann, C. Dean Kurth> ;Anesthesia and Analgesia. 2005 Aug 1
43 citations
Docetaxel and cyclooxygenase-2 inhibition with celecoxib for advanced non-small cell lung cancer progressing after platinum-based chemotherapy: a multicenter phase II ...
Francis W. Nugent, Wilson C. Mertens, Stephen L. Graziano, Nathan Levitan, Rufus Collea, Ajeet Gajra, Janine Marshall, John McCann> ;Lung Cancer. 2005 May 1
46 citations
Apoptotic neuronal death following deep hypothermic circulatory arrest in piglets.
Dara Ditsworth, Margaret A. Priestley, Andreas W. Loepke, Chandra Ramamoorthy, John McCann, Lauren Staple, C. Dean Kurth> ;Anesthesiology. 2003 May 1
33 citations
Desflurane improves neurologic outcome after low-flow cardiopulmonary bypass in newborn pigs.
Andreas W. Loepke, Margaret A. Priestley, Steven E. Schultz, John McCann, Jeffrey A. Golden, C. Dean Kurth> ;Anesthesiology. 2002 Dec 1
170 citations
Near-Infrared Spectroscopy Cerebral Oxygen Saturation Thresholds for Hypoxia–Ischemia in Piglets
C. Dean Kurth, Warren J. Levy, John McCann> ;Journal of Cerebral Blood Flow and Metabolism. 2002 Mar 1
35 citations
Desflurane confers neurologic protection for deep hypothermic circulatory arrest in newborn pigs.
C. Dean Kurth, Margaret A. Priestley, H. Marc Watzman, John McCann, Jeffrey A. Golden> ;Anesthesiology. 2001 Oct 1
69 citations
Comparison of neurologic outcome after deep hypothermic circulatory arrest with alpha-stat and pH-stat cardiopulmonary bypass in newborn pigs.
Margaret A. Priestley, Jeffrey A. Golden, Irene B. O'Hara, John McCann, C. Dean Kurth> ;The Journal of Thoracic and Cardiovascular Surgery. 2001 Feb 1
73 citations
Regional patterns of neuronal death after deep hypothermic circulatory arrest in newborn pigs
C. Dean Kurth, Margaret A. Priestley, Jeffrey A. Golden, John McCann, Ramesh Raghupathi> ;The Journal of Thoracic and Cardiovascular Surgery. 1999 Dec 1
Primary angiosarcoma of the heart in identical twins.
Rosa Hu, James P. Polga, John McCann> ;Journal of Computer Assisted Tomography. 1999 Nov 1
26 citations
High degree of occult tumor contamination in bone marrow and peripheral blood stem cells of patients undergoing autologous transplantation for non-Hodgkin's lymphoma.
John McCann, Rajani Kanteti, Shilepsky B, Kenneth B. Miller, Sweet M, David P. Schenkein> ;Biology of Blood and Marrow Transplantation. 1996 Feb 1
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Press Mentions

Getting Answers: Risks of Lung Cancer in Non-SmokersDecember 17th, 2023

Hospital Affiliations

Baystate Franklin Medical CenterGreenfield, Massachusetts
Baystate Mary Lane HospitalWare, Massachusetts
Baystate Medical CenterSpringfield, Massachusetts
Baystate Wing HospitalPalmer, Massachusetts
Veterans Affairs Central Western Massachusetts Healthcare SystemLeeds, Massachusetts

JohnCMcCannMD

Dr. McCann is on Doximity

Education & Training

Certifications & Licensure

Awards, Honors, & Recognition

Clinical Trials

Publications & Presentations

Press Mentions

Hospital Affiliations

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