JohnWilkinsonMD

Emergency Medicine • Ishpeming, MI

Associate Professor, Laboratory Animal Medicine, University of Michigan Medical School

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Office
101 S 4th St
Ishpeming, MI 49849
Phone+1 906-486-4431

Fax+1 906-485-2504
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Summary

Dr. John Wilkinson, MD is an emergency medicine physician in Ishpeming, Michigan. He is currently licensed to practice medicine in Michigan. He is affiliated with Oscar G. Johnson Department of Veterans Affairs Medical Facility and is an Associate Professor at University of Michigan Medical School.

Education & Training

Indiana University Health Ball Memorial HospitalResidency, Family Medicine, 1980 - 1983
Indiana University School of MedicineClass of 1980

Certifications & Licensure

MI State Medical License Active through 2013

Publications & Presentations

PubMed

The PHLPP2 phosphatase is a druggable driver of prostate cancer progression.
Nowak, D. G.,Katsenelson, K. C.,Watrud, K. E.,Chen, M.,Mathew, G.,D'Andrea, V. D.,Lee, M. F.,Swamynathan, M. M.,Casanova-Salas, I.,Jibilian, M. C.,Buckholtz, C. L.,Amb...> ;J. Cell Biol.. 2019 May 17
Acarbose improves health and lifespan in aging HET3 mice.
Harrison, D. E.,Strong, R.,Alavez, S.,Astle, C. M.,DiGiovanni, J.,Fernandez, E.,Flurkey, K.,Garratt, M.,Gelfond, JAL.,Javors, M. A.,Levi, M.,Lithgow, G. J.,Macchiarini...> ;Aging Cell. 2019 Jan 29
Arid1a restrains Kras-dependent changes in acinar cell identity.
Livshits, G.,Alonso-Curbelo, D.,Morris, J. P.,Koche, R.,Saborowski, M.,Wilkinson, J. E.,Lowe, S. W.> ;Elife. 2018 Jul 18
POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer.
Huang, Y. H.,Klingbeil, O.,He, X. Y.,Wu, X. S.,Arun, G.,Lu, B.,Somerville, TDD.,Milazzo, J. P.,Wilkinson, J. E.,Demerdash, O. E.,Spector, D. L.,Egeblad, M.,Shi, J.,Vak...> ;Genes Dev.. 2018 Jun 28
Asparagine Bioavailability Governs Metastasis in a Model of Breast Cancer
Lisa A Carey, John E Wilkinson> ;Nature. 2018 Feb 08
A TFIID-SAGA Perturbation That Targets MYB and Suppresses Acute Myeloid Leukemia
John Wilkinson, MD> ;Cell Press. 2018 Jan 10
DNAJB1-PRKACA fusion kinase interacts with β-catenin and the liver regenerative response to drive fibrolamellar hepatocellular carcinoma.
Kastenhuber, E. R.,Lalazar, G.,Houlihan, S. L.,Tschaharganeh, D. F.,Baslan, T.,Chen, C. C.,Requena, D.,Tian, S.,Bosbach, B.,Wilkinson, J. E.,Simon, S. M.,Lowe, S. W.> ;Proc. Natl. Acad. Sci. U.S.A.. 2017 Nov 23
Apoptosis-induced CXCL5 accelerates inflammation and growth of prostate tumor metastases in bone.
Roca, H.,Jones, J. D.,Purica, M. C.,Weidner, S.,Koh, A. J.,Kuo, R.,Wilkinson, J. E.,Wang, Y.,Daignault-Newton, S.,Pienta, K. J.,Morgan, T. M.,Keller, E. T.,Nör, J. E.,...> ;J. Clin. Invest.. 2017 Dec 05
23 citations
Doxycycline induces dysbiosis in female C57BL/6NCrl mice.
Felicia D. Duke Boynton, Aaron C. Ericsson, Mayu Uchihashi, Misha L Dunbar, J. Erby Wilkinson> ;BMC Research Notes. 2017 Nov 29
27 citations
Overactive mTOR signaling leads to endometrial hyperplasia in aged women and mice
Preety Bajwa, Sarah Nielsen, Janine M. Lombard, Loui Rassam, Pravin Nahar, Bo R. Rueda, J. Erby Wilkinson, Richard A. Miller, Pradeep S. Tanwar> ;Oncotarget. 2017 Jan 31
NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.
Chio, I. I.,Jafarnejad, S. M.,Ponz-Sarvise, M.,Park, Y.,Rivera, K.,Palm, W.,Wilson, J.,Sangar, V.,Hao, Y.,Öhlund, D.,Wright, K.,Filippini, D.,Lee, E. J.,Da Silva, B.,S...> ;Cell. 2016 Aug 02
13 citations
Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium
Preety Bajwa, Prathima B. Nagendra, Sarah Nielsen, Subhransu S. Sahoo, Amanda Bielanowicz, Janine M. Lombard, J. Erby Wilkinson, Richard A. Miller, Pradeep S. Tanwar> ;Oncotarget. 2016 Mar 30
417 citations
Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss
Gayatri Arun, Sarah D. Diermeier, Martin Akerman, Kung-Chi Chang, J. Erby Wilkinson, Stephen Hearn, Youngsoo Kim, A. Robert MacLeod, Adrian R. Krainer, Larry Norton, E...> ;Genes & Development. 2016 Jan 1
ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms.
Palmbos, P. L.,Wang, L.,Yang, H.,Wang, Y.,Leflein, J.,Ahmet, M. L.,Wilkinson, J. E.,Kumar-Sinha, C.,Ney, G. M.,Tomlins, S. A.,Daignault, S.,Kunju, L. P.,Wu, X. R.,Lota...> ;Cancer Res.. 2015 Oct 17
58 citations
TGF-β/Smad signaling through DOCK4 facilitates lung adenocarcinoma metastasis
Jia Ray Yu, Yilin Tai, Ying Jin, Molly Hammell, J. Erby Wilkinson, Jae Seok Roe, Christopher R. Vakoc, Linda Van Aelst> ;Genes & Development. 2015 Feb 1
29 citations
Proinflammatory Effects of Interferon Gamma in Mouse Adenovirus 1 Myocarditis
Mary K. McCarthy, Megan C. Procario, Nele Twisselmann, J. Erby Wilkinson, Ashley J. Archambeau, Daniel E. Michele, Sharlene M. Day, Jason B. Weinberg> ;Journal of Virology. 2015 Jan 1
Resident Alveolar Macrophages Suppress, whereas Recruited Monocytes Promote, Allergic Lung Inflammation in Murine Models of Asthma.
Zasłona, Z.,Przybranowski, S.,Wilke, C.,van Rooijen, N.,Teitz-Tennenbaum, S.,Osterholzer, J. J.,Wilkinson, J. E.,Moore, B. B.,Peters-Golden, M.> ;J. Immunol.. 2014 Sep 17
264 citations
Acarbose, 17‐α‐estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males
David E. Harrison, Randy Strong, David B. Allison, Bruce N. Ames, Clinton M. Astle, Hani Atamna, Elizabeth Fernandez, Kevin Flurkey, Martin A. Javors, Nancy L. Nadon, ...> ;Aging Cell. 2014 Apr 1
223 citations
A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression
Nobuhiro Okada, Chao Po Lin, Marcelo C. Ribeiro, Anne Biton, Gregory Lai, Xingyue He, Pengcheng Bu, Hannes Vogel, David M. Jablons, Andreas Keller, J. Erby Wilkinson, ...> ;Genes & Development. 2014 Mar 1
9 citations
Histotripsy Effects on the Bladder Trigone: Functional and Histologic Consequences in the Canine Model
Christopher L. Allam, J. Erby Wilkinson, Xu Cheng, Kimberly Ives, Timothy L. Hall, William W. Roberts> ;Journal of Endourology. 2013 Oct 1
166 citations
The unfolded protein response and chemical chaperones reduce protein misfolding and colitis in mice.
Stewart Siyan Cao, Ellen M. Zimmermann, Brandy–Mengchieh Chuang, Benbo Song, Anosike Nwokoye, J. Erby Wilkinson, Kathryn A. Eaton, Randal J. Kaufman> ;Gastroenterology. 2013 May 1
Rapamycin slows aging in mice.
Wilkinson, J. E.,Burmeister, L.,Brooks, S. V.,Chan, C. C.,Friedline, S.,Harrison, D. E.,Hejtmancik, J. F.,Nadon, N.,Strong, R.,Wood, L. K.,Woodward, M. A.,Miller, R. A.> ;Aging Cell. 2012 May 17
656 citations
Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
Richard A. Miller, David E. Harrison, Clinton M. Astle, Joseph A. Baur, Angela R. Boyd, Rafael de Cabo, Elizabeth Fernandez, Kevin Flurkey, Martin A. Javors, James F. ...> ;The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2011 Feb 1
21 citations
Examining and Analyzing Subcellular Morphology of Renal Tissue Treated by Histotripsy
Frank Winterroth, Zhen Xu, Tzu-Yin Wang, J. Erby Wilkinson, J. Brian Fowlkes, William W. Roberts, Charles A. Cain> ;Ultrasound in Medicine & Biology. 2011 Jan 1
47 citations
Macrophage migration inhibitory factor-knockout mice are long lived and respond to caloric restriction.
James M. Harper, J. Erby Wilkinson, Richard A. Miller> ;FASEB Journal. 2010 Jul 1
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Press Mentions

The First Effective Chemotherapy for CancerNovember 6th, 2020

Hospital Affiliations

Oscar G. Johnson Department of Veterans Affairs Medical FacilityIron Mountain, Michigan