Jonathan Halford, MD, Neurology, Charleston, SC, Ralph H. Johnson Veterans Affairs Medical Center


Neurology Charleston, SC

Epilepsy, Neurophysiology, Sleep Medicine

Professor of Neurology at the Medical University of South Carolina and Staff Neurologist at the Ralph H. Johnson VAMC

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  • Dr. Halford is a native of South Carolina and grew up in Charleston. He graduated Cum Laude from Duke University with a major in Religious Studies in 1990. After time off to work in medical missions in the Amazon area of Brazil, he attended medical school at the Medical University of South Carolina where he graduated in 1996. He was a neuro-anatomy instructor part-time as a medical student and he won the AMSA Special Appreciation Award from for teaching medical students in 1993.

    After medical school, he spent one year training in Internal Medicine at Virginia Commonwealth University and spent six years training at Duke University Medical Center, where he completed a dual neurology-psychiatry residency training program and a neurophysiology fellowship. He accepted a faculty position in the Department of Neurology at MUSC in 2003.

    Dr. Halford cares for epilepsy patients both at the Medical University of South Carolina (MUSC) and at the Ralph H. Johnson VA Medical Center in Charleston, SC. He is very involved in epilepsy research in two areas. First, he works to run clinical trials of new anti-seizure medications and seizure detection devices. Secondly, he helps develop automated computer detection systems using electroencephalopgrahy (EEG) and electromyography (EMG) signals. Dr. Halford is the Director of the Translational Research Unit for the Departments of Neurology and Neurosurgery at MUSC. He is also the Director of the Associate Consortium Site at the Charleston Veterans Hospital for the VA Epilepsy Centers of Excellence. He is an Adjunct Associate Professor in the Departments of Electrical and Computer Engineering and the School of Computing at Clemson University.

    Dr. Halford sees adults with epilepsy at the MUSC Rutledge Clinical Tower Clinic and at the Epilepsy Subspecialty Clinic and the Ralph H. Johnson VA Medical Center.

Education & Training

  • Duke University Hospital
    Duke University HospitalFELLOWSHIP
  • Duke University Hospital
    Duke University HospitalRESIDENCY
  • Duke University Hospital
    Duke University HospitalRESIDENCY
  • Virginia Commonwealth University Health System
    Virginia Commonwealth University Health SystemINTERNSHIP
  • Medical University of South Carolina College of Medicine
    Medical University of South Carolina College of MedicineMEDICAL_SCHOOL
  • Duke University
    Duke UniversityOTHER_TRAINING

Certifications & Licensure

  • NC State Medical License
    NC State Medical License 2015 - 2016
  • SC State Medical License
    SC State Medical License 2003 - 2021
  • American Board of Psychiatry and Neurology Neurology
  • American Board of Psychiatry and Neurology Psychiatry
  • American Board of Psychiatry and Neurology Epilepsy
  • American Board of Clinical NeurophysiologyAdvanced Electroencephalography and Epilepsy Monitoring
  • American Board of Sleep MedicineSleep Medicine
  • DEA and SC DHECClass 1 Prescription License

Awards, Honors, & Recognition

  • Fellow American Epilepsy Society, 2016
  • Fellow American Clinical Neurophysiology Society, 2014
  • Golden Apple Special Appreciation Award Medical University of South Carolina, 1996

Clinical Trials

Publications & Presentations


Journal Articles

  • Standardized Database Development for EEG Epileptiform Transient Detection: EEGnet Scoring System and Machine Learning Analysis  
    Halford JJ, Schalkoff RJ, Zhou J, Benbadis SR, Tatum WO, Turner RP, Sinha S, Fountain NB, Arain A, Pritchard PB, Kutluay E, Martz G, Edwards JC, Waters C, Dean BC, Journal of Neurosciences Methods, 1/1/2013
  • Hippocampal atrophy in temporal lobe epilepsy: the generator and receiver  
    Bonilha L, Halford JJ, Morgan PS, Edwards JC, Acta Neurologica Scandanavia, 2/1/2012
  • Quantitative EEG Analysis for Automated Detection of Nonconvulsive Seizures in Intensive Care Units  
    Sackellares JC, Shiau DS, Halford JJ, LaRoche SM, Kelly KM, Epilepsy & Behavior, 1/1/2011
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Professional Memberships

Hospital Affiliations