JonathanAndrewNowakMD

PubMed

• Alcohol and colorectal cancer risk subclassified by mutational signatures of DNA mismatch repair deficiency.
  Aiping Fang, Tomotaka Ugai, Carino Gurjao, Rong Zhong, Zhenhua Liu, Xinyuan Zhang, Peilu Wang, Molin Wang, Xuehong Zhang, Edward Giovannucci, Jonathan Nowak, Marios Gi...> ;Journal of the National Cancer Institute. 2024 Apr 4
• Epidemiologic Factors in Relation to Colorectal Cancer Risk and Survival by Genotoxic Colibactin Mutational Signature.
  Claire E Thomas, Peter Georgeson, Conghui Qu, Robert S Steinfelder, Daniel D Buchanan, Mingyang Song, Tabitha A Harrison, Caroline Y Um, Meredith A Hullar, Mark A Jenk...> ;Cancer Epidemiology, Biomarkers & Prevention. 2024 Apr 3
• Quantitative Multiplexed Analysis of Indoleamine 2,3-Dioxygenase (IDO) and Arginase-1 (ARG1) Expression and Myeloid Cell Infiltration in Colorectal Cancer.
  Elomaa, H., Härkönen, J., Väyrynen, S., Ahtiainen, M., Lau, M., Helminen, O., Wirta, E., Seppälä, T., Böhm, J., Mecklin, J., Kuopio, T., Väyrynen, J., Ogino, S., Nowak...> ;Modern Pathology. 2024 Feb 16
• Cancer Diagnoses After Recent Weight Loss.
  Wang, Q., Babic, A., Rosenthal, M., Lee, A., Zhang, Y., Zhang, X., Song, M., Rezende, L., Lee, D., Biller, L., Ng, K., Giannakis, M., Chan, A., Meyerhardt, J., Fuchs, ...> ;JAMA. 2024 Jan 23
• Enrichment of Bacteroides fragilis and enterotoxigenic Bacteroides fragilis in CpG island methylator phenotype-high colorectal carcinoma.
  Takashima, Y., Kawamura, H., Okadome, K., Ugai, S., Haruki, K., Arima, K., Mima, K., Akimoto, N., Song, M., Ugai, T., Nowak, J., Giannakis, M., Garrett, W., Sears, C.,...> ;Clinical Microbiology and Infection. 2024 Jan 22
• 1 citations
  Protein biomarkers and alternatively methylated cell-free DNA detect early stage pancreatic cancer.
  Roni Ben-Ami, Qiao-Li Wang, Jinming Zhang, Julianna G Supplee, Johannes F Fahrmann, Roni Lehmann-Werman, Lauren K Brais, Jonathan Nowak, Chen Yuan, Maureen Loftus, Ana...> ;Gut. 2024 Mar 7
• Pathologic Evaluation of Therapeutic Biomarkers in Colorectal Adenocarcinoma.
  Esther Baranov, Jonathan A Nowak> ;Surgical Pathology Clinics. 2023 Dec 1
• Machine learning links T cell function and spatial localization to neoadjuvant immunotherapy and clinical outcome in pancreatic cancer.
  Katie E Blise, Shamilene Sivagnanam, Courtney B Betts, Konjit Betre, Nell Kirchberger, Benjamin Tate, Emma E Furth, Andressa Dias Costa, Jonathan A Nowak, Brian M Wolp...> ;Biorxiv. 2023 Oct 23
• 2 citations
  Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity.
  Moon Hee Yang, Timothy H Tran, Bethany Hunt, Rebecca Agnor, Christian W Johnson, Bing Shui, Timothy J Waybright, Jonathan A Nowak, Andrew G Stephen, Dhirendra K Simans...> ;Cancer Research. 2023 Oct 2
• Vitamin C intake and colorectal cancer survival according to KRAS and BRAF mutation: a prospective study in two US cohorts.
  Shanshan Shi, Kai Wang, Tomotaka Ugai, Marios Giannakis, Jules Cazaubiel, Andrew T Chan, Edward L Giovannucci, Jonathan A Nowak, Jeffrey A Meyerhardt, Shuji Ogino, Min...> ;British Journal of Cancer. 2023 Nov 1
• 6 citations
  Adipose tissue and skeletal muscle wasting precede clinical diagnosis of pancreatic cancer.
  Ana Babic, Michael H Rosenthal, Tilak K Sundaresan, Natalia Khalaf, Valerie Lee, Lauren K Brais, Maureen Loftus, Leah Caplan, Sarah Denning, Anamol Gurung, Joanna Harr...> ;Nature Communications. 2023 Jul 18
• 2 citations
  Bayesian risk prediction model for colorectal cancer mortality through integration of clinicopathologic and genomic data.
  Melissa Zhao, Mai Chan Lau, Koichiro Haruki, Juha P Väyrynen, Carino Gurjao, Sara A Väyrynen, Andressa Dias Costa, Jennifer Borowsky, Kenji Fujiyoshi, Kota Arima, Tsuy...> ;NPJ Precision Oncology. 2023 Jun 10
• Pancreatic cancer is associated with medication changes prior to clinical diagnosis.
  Yin Zhang, Qiao-Li Wang, Chen Yuan, Alice A Lee, Ana Babic, Kimmie Ng, Kimberly Perez, Jonathan A Nowak, Jesper Lagergren, Meir J Stampfer, Edward L Giovannucci, Chris...> ;Nature Communications. 2023 Apr 28
• 8 citations
  Spatially resolved multimarker evaluation of CD274 (PD-L1)/PDCD1 (PD-1) immune checkpoint expression and macrophage polarisation in colorectal cancer.
  Hanna Elomaa, Maarit Ahtiainen, Sara A Väyrynen, Shuji Ogino, Jonathan A Nowak, Mai Chan Lau, Olli Helminen, Erkki-Ville Wirta, Toni T Seppälä, Jan Böhm, Jukka-Pekka M...> ;British Journal of Cancer. 2023 Jun 1
• 3 citations
  Genotoxic colibactin mutational signature in colorectal cancer is associated with clinicopathological features, specific genomic alterations and better survival.
  Peter Georgeson, Robert S Steinfelder, Tabitha A Harrison, Bernard J Pope, Syed H Zaidi, Conghui Qu, Yi Lin, Jihoon E Joo, Khalid Mahmood, Mark Clendenning, Romy Walke...> ;Medrxiv. 2024 Jan 30
• 1 citations
  Clinical Targeted Next-Generation Panel Sequencing RevealsAmplification Is a Poor Prognostic Factor in Osteosarcoma.
  Amanda E Marinoff, Liam F Spurr, Christina Fong, Yvonne Y Li, Suzanne J Forrest, Abigail Ward, Duong Doan, Laura Corson, Audrey Mauguen, Navin Pinto, Luke Maese, Susan...> ;JCO Precision Oncology. 2023 Mar 1
• 1 citations
  Helicobacter pylori Seropositivity, ABO Blood Type, and Pancreatic Cancer Risk From 5 Prospective Cohorts.
  Alice A Lee, Qiao-Li Wang, Jihye Kim, Ana Babic, Xuehong Zhang, Kimberly Perez, Kimmie Ng, Jonathan Nowak, Nader Rifai, Howard D Sesso, Julie E Buring, Garnet L Anders...> ;Clinical and Translational Gastroenterology. 2023 May 1
• 13 citations
  Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity.
  Hannah L Williams, Andressa Dias Costa, Jinming Zhang, Srivatsan Raghavan, Peter S Winter, Kevin S Kapner, Scott P Ginebaugh, Sara A Väyrynen, Juha P Väyrynen, Chen Yu...> ;Cancer Research. 2023 Feb 3
• 6 citations
  Molecular Characteristics of Early-Onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison With Later-Onset Cases.
  Tomotaka Ugai, Koichiro Haruki, Tabitha A Harrison, Yin Cao, Conghui Qu, Andrew T Chan, Peter T Campbell, Naohiko Akimoto, Sonja Berndt, Hermann Brenner, Daniel D Buch...> ;The American Journal of Gastroenterology. 2023 Apr 1
• 7 citations
  Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases.
  Tomotaka Ugai, Naohiko Akimoto, Koichiro Haruki, Tabitha A Harrison, Yin Cao, Conghui Qu, Andrew T Chan, Peter T Campbell, Sonja I Berndt, Daniel D Buchanan, Amanda J ...> ;Journal of Gastroenterology. 2023 Mar 1
• Inverse relationship betweenamount and tumor CD274 (PD-L1) expression in colorectal carcinoma.
  Tomotaka Ugai, Takashi Shimizu, Hidetaka Kawamura, Satoko Ugai, Yasutoshi Takashima, Genki Usui, Juha P Väyrynen, Kazuo Okadome, Koichiro Haruki, Naohiko Akimoto, Yohe...> ;Clinical & Translational Immunology. 2023 Jan 1
• 16 citations
  Neoadjuvant Chemotherapy Is Associated with Altered Immune Cell Infiltration and an Anti-Tumorigenic Microenvironment in Resected Pancreatic Cancer.
  Andressa Dias Costa, Sara A Väyrynen, Akhil Chawla, Jinming Zhang, Juha P Väyrynen, Mai Chan Lau, Hannah L Williams, Chen Yuan, Vicente Morales-Oyarvide, Dalia Elganai...> ;Clinical Cancer Research. 2022 Dec 1
• 8 citations
  Body mass index and molecular subtypes of colorectal cancer.
  Neil Murphy, Christina C Newton, Mingyang Song, Nikos Papadimitriou, Michael Hoffmeister, Amanda I Phipps, Tabitha A Harrison, Polly A Newcomb, Elom K Aglago, Sonja I ...> ;Journal of the National Cancer Institute. 2023 Feb 8
• 4 citations
  Prognostic role of inflammatory diets in colorectal cancer overall and in strata of tumor-infiltrating lymphocyte levels.
  Tomotaka Ugai, Li Liu, Fred K Tabung, Tsuyoshi Hamada, Benjamin W Langworthy, Naohiko Akimoto, Koichiro Haruki, Yasutoshi Takashima, Kazuo Okadome, Hidetaka Kawamura, ...> ;Clinical and Translational Medicine. 2022 Nov 1
• 22 citations
  NCOA4-Mediated Ferritinophagy Is a Pancreatic Cancer Dependency via Maintenance of Iron Bioavailability for Iron-Sulfur Cluster Proteins.
  Naiara Santana-Codina, Maria Quiles Del Rey, Kevin S Kapner, Huan Zhang, Ajami Gikandi, Callum Malcolm, Clara Poupault, Miljan Kuljanin, Kristen M John, Douglas E Bian...> ;Cancer Discovery. 2022 Sep 2
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