JonathanQuentinPurnellMD

Endocrinology • Portland, OR

Diabetes, Lipid Metabolism

Associate Professor, Medicine, Oregon Health and Science University School of Medicine

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Office
3181 Sw Sam Jackson Park Rd
Portland, OR 97239
Phone(503) 494-1056
Fax(503) 494-6969
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Education & Training

University of WashingtonFellowship, Endocrinology, Diabetes and Metabolism, 1993 - 1996
University of Vermont - Fletcher Allen Health CareResidency, Internal Medicine, 1986 - 1990
Oregon Health & Science University School of MedicineClass of 1986

Certifications & Licensure

OR State Medical License 2000 - 2021
MD State Medical License 1990 - 1993
VT State Medical License 1986 - 1990
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2013

Clinical Trials

Magnetic Resonance Spectroscopic Imaging Study of Prostatic Fats to Distinguish the Difference Between High and Low Risk Prostate Cancer Start of enrollment: 2013 Jan 01Shannon, J.,Purnell, J.Q.
The Role of R-alpha Lipoic Acid in Treatment of Atherosclerotic Vascular Disease Start of enrollment: 2011 Aug 01Purnell, J.Q.
Ghrelin Regulation and Structure: Effect of Thiazolidinedione Therapy on Ghrelin Start of enrollment: 2009 Feb 01Klopfenstein, B.,Purnell, J.Q.
The Role of R-alpha Lipoic Acid in Prevention of Atherosclerotic Vascular Disease Start of enrollment: 2009 Jan 01Bacon, S.,Frei, B.,Purnell, J.Q.
LABS-3 Diabetes: Mechanisms for Improvement of Type 2 Diabetes Following Bariatric Surgery Start of enrollment: 2008 Mar 01Purnell, J.
Ghrelin Regulation and Structure: Effect of Diet Composition on Ghrelin Start of enrollment: 2008 Feb 01Purnell, J.Q.
Cortisol Regulation in Polycystic Ovary Syndrome Start of enrollment: 2006 Oct 01Klopfenstein, B.J.,Purnell, J.Q.
Hypothalamic fMRI Response to Nutrients Start of enrollment: 2006 Oct 01Purnell, J.Q.
A Study of the Functional Magnetic Resonance Imaging Response to Leptin and Pramlintide Start of enrollment: 2006 Jan 01Purnell, J.Q.
Effects of Low Dose Growth Hormone (GH) Therapy on Insulin Sensitivity, Adipocyte Insulin-Like Growth Factor-I (IGF-I) and IGF-I/Insulin Receptor Density and Regulation of Cortisol Metabolism in GH Deficient Adults Start of enrollment: 2006 Jan 01Cook, D.M.,Purnell, J.Q.,Roberts, C.T.,Yuen, K.C.
Regulation of Cortisol Metabolism and Fat Patterning Start of enrollment: 2005 May 01Purnell, J.Q.
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Publications & Presentations

PubMed

Diabetes Remission Status During Seven-year Follow-up of the Longitudinal Assessment of Bariatric Surgery Study.
Jonathan Q. Purnell, Elizabeth Dewey, Blandine Laferrère, Faith Selzer, David R. Flum, James E. Mitchell, Alfons Pomp, Walter J. Pories, Thomas H. Inge, Anita P. Courc...> ;The Journal of Clinical Endocrinology and Metabolism. 2020 Dec 3
Associations of Pregnancy After Bariatric Surgery with Long‐Term Weight Trajectories and Birth Weight: LABS‐2 Study
Curtis S. Harrod, Miriam R. Elman, Kimberly K Vesco, Bruce M. Wolfe, James E. Mitchell, Walter J. Pories, Alfons Pomp, Janne Boone-Heinonen, Jonathan Q. Purnell> ;Obesity. 2020 Sep 11
Short-term intestinal lipase inhibition in normal-weight individuals does not affect postprandial peptide YY3-36 and glucagon-like peptide-1 levels, hunger or satiety.
Nga N. Nguyen, Irina Kolobova, Bruce M. Wolfe, Jonathan Q. Purnell> ;Diabetes, Obesity and Metabolism. 2020 Sep 1
A Randomized Controlled Trial of Long-Term (R)-α-Lipoic Acid Supplementation Promotes Weight Loss in Overweight or Obese Adults without Altering Baseline Elevated Plas...
Gerd Bobe, Alexander J. Michels, Wei-Jian Zhang, Jonathan Q. Purnell, Clive Woffendin, Cliff Pereira, Joseph A. Vita, Nicholas O. Thomas, Maret G. Traber, Balz Frei, T...> ;Journal of Nutrition. 2020 Sep 1
Exclusive Breastfeeding Rates at 6 Weeks Postpartum as a Function of Preconception Body Mass Index Are Not Impacted by Postpartum Obstetrical Practices or Routines.
Marshall, N. E., Lallande, L. F., Schedin, P. J., Thornburg, K. L., Purnell, J. Q.> ;Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine. 2020 May 16
DNA methylation age calculators reveal association with diabetic neuropathy in type 1 diabetes.
Delnaz Roshandel, Zhuo Chen, Angelo J. Canty, Shelley B. Bull, Rama Natarajan, Andrew D. Paterson, Stephen W. Scherer, F. Miao, L. Zhang, J. Brown-Friday, Jill P. Cran...> ;Clinical Epigenetics. 2020 Apr 5
The Association Between Kidney Disease and Diabetes Remission in Bariatric Surgery Patients With Type 2 Diabetes.
Allon N. Friedman, Junyao Wang, Abdus S. Wahed, Neil G. Docherty, Erin B. Fennern, Alfons Pomp, Jonathan Q. Purnell, Carel W. le Roux, Bruce M. Wolfe> ;American Journal of Kidney Diseases. 2019 Dec 1
Association between weight loss and serum biomarkers with risk of incident cancer in the Longitudinal Assessment of Bariatric Surgery cohort.
Andrea M. Stroud, Elizabeth Dewey, Farah Husain, Jared M. Fischer, Anita P. Courcoulas, David R. Flum, James E. Mitchell, Walter J. Pories, Jonathan Q. Purnell, Bruce ...> ;Surgery for Obesity and Related Diseases. 2019 Oct 1
Higher dietary protein intake preserves lean body mass, lowers liver lipid deposition, and maintains metabolic control in participants with long-chain fatty acid oxida...
Gillingham, M. B., Elizondo, G., Behrend, A., Matern, D., Schoeller, D. A., Harding, C. O., Purnell, J. Q.> ;Journal of inherited metabolic disease. 2019 Jul 12
Conception rates and contraceptive use after bariatric surgery among women with infertility: Evidence from a prospective multicenter cohort study
Marie Menke, Wendy C. King, Gretchen E. White, Gabriella G. Gosman, Anita P. Courcoulas, Gregory Dakin, David R. Flum, Molly Orcutt, Alfons Pomp, Walter J. Pories, Jon...> ;Surgery for Obesity and Related Diseases. 2019 May 1
The Role of Glucagon-Like Peptide-1 in Energy Homeostasis
Marzieh Salehi, Jonathan Q. Purnell> ;Metabolic Syndrome and Related Disorders. 2019 Apr 27
Impact of maternal obesity and breastfeeding intention on lactation intensity and duration
Nicole Marshall, Bernard Lau, Jonathan Q. Purnell, Kent L. Thornburg> ;Maternal and Child Nutrition. 2019 Apr 1
Effect of the Anti-Inflammatory Diet in People with Diabetes and Pre-Diabetes: A Randomized Controlled Feeding Study.
Heather Zwickey, Angela Horgan, Doug Hanes, Heather C Schiffke, Annie Moore, Helané Wahbeh, Julia Jordan, Lila Ojeda, Martha P. McMurry, Patricia J. Elmer, Jonathan Q....> ;Journal of restorative medicine. 2019 Feb 15
Estradiol Replacement Timing and Obesogenic Diet Effects on Body Composition and Metabolism in Postmenopausal Macaques.
Purnell, J. Q., Urbanski, H. F., Kievit, P., Roberts, C. T., Bethea, C. L.> ;Endocrinology. 2019 Feb 13
Bariatric/Metabolic Surgery for Diabetes: Lessons From the Past and Present
Jonathan Q. Purnell, Bruce M. Wolfe> ;Diabetes Care. 2019 Feb 1
Serum biomarkers of inflammation and adiposity in the LABS cohort: associations with metabolic disease and surgical outcomes.
Robert W. O'Rourke, Geoffrey S. Johnson, Jonathan Q. Purnell, Anita P. Courcoulas, Gregory Dakin, Luis Garcia, Marcelo W. Hinojosa, James E. Mitchell, Alfons Pomp, Wal...> ;International Journal of Obesity. 2019 Feb 1
Application of PCSK9 Inhibitors in Practice
Tina M. Kaufman, Bruce A. Warden, Jessica Minnier, Joshua Miles, P. Barton Duell, Jonathan Q. Purnell, Cezary Wojcik, Sergio Fazio, Michael D. Shapiro> ;Circulation Research. 2019 Jan 4
Effects of Altering Levothyroxine Dose on Energy Expenditure and Body Composition in Subjects Treated With LT4
Mary H. Samuels, Irina Kolobova, Meike Niederhausen, Jonathan Q. Purnell, Kathryn G. Schuff> ;The Journal of Clinical Endocrinology and Metabolism. 2018 Nov 1
Inflammatory Determinants of Pregravid Obesity in Placenta and Peripheral Blood.
Suhas Sureshchandra, Nicole Marshall, Randall M. Wilson, Tasha Barr, Maham Rais, Jonathan Q. Purnell, Kent L. Thornburg, Ilhem Messaoudi> ;Frontiers in Physiology. 2018 Aug 7
Effects of postweaning calorie restriction on accelerated growth and adiponectin in nutritionally programmed microswine offspring.
DuPriest, E. A., Lin, B., Kupfer, P., Sekiguchi, K., Bhusari, A., Quackenbush, A., Celebic, A., Morgan, T. K., Purnell, J. Q., Bagby, S. P.> ;American journal of physiology. Regulatory, integrative and comparative physiology. 2018 Jun 21
Poorer maternal diet quality and increased birth weight
Madeline Grandy, Jonathan M. Snowden, Janne Boone-Heinonen, Jonathan Q. Purnell, Kent L. Thornburg, Nicole Marshall> ;Journal of Maternal-fetal & Neonatal Medicine. 2018 Jun 18
Metals in Urine in Relation to the Prevalence of Pre-Diabetes, Diabetes and Atherosclerosis in Rural India
Jonathan Purnell, MD> ;Emergency Medicine Journal.
Prospective evaluation of insulin and incretin dynamics in obese adults with and without diabetes for 2 years after Roux-en-Y gastric bypass.
Jonathan Q. Purnell, Geoffrey S. Johnson, Abdus S. Wahed, Chiara Dalla Man, Francesca Piccinini, Claudio Cobelli, Ronald L. Prigeon, Bret H. Goodpaster, David E. Kelle...> ;Diabetologia. 2018 Feb 10
2 citations
Effect of Bariatric Surgery on CKD Risk.
Allon N. Friedman, Abdus S. Wahed, Junyao Wang, Anita P. Courcoulas, Gregory Dakin, Marcelo W. Hinojosa, Paul L. Kimmel, James Mitchell, Alfons Pomp, Walter J. Pories,...> ;Journal of The American Society of Nephrology. 2018 Jan 15
6 citations
Seven-Year Weight Trajectories and Health Outcomes in the Longitudinal Assessment of Bariatric Surgery (LABS) Study.
Anita P. Courcoulas, Wendy C. King, Steven H. Belle, Paul D. Berk, David R. Flum, Luis Garcia, William Gourash, Mary Horlick, James E. Mitchell, Alfons Pomp, Walter J....> ;JAMA Surgery. 2017 Dec 6
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Press Mentions

Weight-Loss Surgery Often Rids Patients of Type 2 DiabetesDecember 03, 2020 12:34
Poster AbstractsNovember 09, 2020 12:17
The Best Food and Supplements for PMSMarch 14, 2020 06:29
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Grant Support

Regulation Of Brain Signaling After Bariatric SurgeryNational Institute Of Diabetes And Digestive And Kidney Diseases2010
Structure And Regulation Of Ghrelin In ObesityNational Institute Of Diabetes And Digestive And Kidney Diseases2007–2010
Hypothalamic FMRI Response To NutrientsNational Institute Of Diabetes And Digestive And Kidney Diseases2006–2007
Regulation Of Cortisol Metabolism And Fat PatterningNational Institute Of Diabetes And Digestive And Kidney Diseases2004–2007
Hypothalamic FMRI Response To NutrientsNational Center For Research Resources2005
Change In Leptin As A Predictor Of Satiety With High Protein FeedingNational Center For Research Resources2005
Menopause, CPR, And Visceral FatNational Center For Research Resources2004–2005
Long Term Studies In Addison'S PatientsNational Center For Research Resources2004–2005
Ectopic Fat In Insulin Resistance And DiabetesNational Center For Research Resources2004–2005
Change In Leptin As A Predictor Of Satiety With High Protein Feeding.National Center For Research Resources2004
Sex Steroid, HPA Regulation, And Fat PatterningNational Institute Of Diabetes And Digestive And Kidney Diseases2002–2003
Cortisol, Central Obesity, And Insulin ResistanceNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2003
Cortisol Production Rate &Insulin Resistance In ObesityNational Center For Research Resources2000–2002
Cortisol Production Rate And Insulin Resistance In ObesityNational Center For Research Resources1998–2000

Hospital Affiliations

VA Portland Healthcare SystemPortland, Oregon
OHSU HospitalPortland, Oregon