JordanAShavitMDPhD

PubMed

• Composition of thrombi in zebrafish: similarities and distinctions with mammals.
  Megan S Griffin, Anna R Dahlgren, Chandrasekaran Nagaswami, Rustem I Litvinov, Kevin Keeler, Charles Madenjian, Ricardo Fuentes, Richard J Fish, Marguerite Neerman-Arb...> ;Journal of Thrombosis and Haemostasis. 2024 Apr 1
• 1 citations
  A novel leukocyte adhesion deficiency type III mutation manifests functional importance of the compact FERM domain in kindlin-3.
  Zhen Xu, Shawn M Jobe, Yan-Qing Ma, Jordan A Shavit> ;Journal of Thrombosis and Haemostasis. 2024 Feb 1
• 8 citations
  Building the foundation for a community-generated national research blueprint for inherited bleeding disorders: facilitating research through infrastructure, workforce...
  Margaret V Ragni, Guy Young, Glaivy Batsuli, Emily Bisson, Shannon L Carpenter, Stacy E Croteau, Adam Cuker, Randall G Curtis, Michael Denne, Bruce Ewenstein, Amber Fe...> ;Expert Review of Hematology. 2023 Mar 1
• CRISPR/Cas9-Mediated Genome Editing in Zebrafish.
  Jeffrey G Daniel, Xinge Yu, Allison C Ferguson, Jordan A Shavit> ;Methods in Molecular Biology. 2023 Jan 1
• 3 citations
  Direct delivery of plasmin using clot-anchoring thrombin-responsive nanoparticles for targeted fibrinolytic therapy.
  Michael Sun, M Hao Hao Pontius, Stephanie Yang, Tejal Pendekanti, Shruti Raghunathan, Jordan A Shavit, Anirban Sen Gupta> ;Journal of Thrombosis and Haemostasis. 2023 Apr 1
• 2 citations
  Genetic duplication of tissue factor reveals subfunctionalization in venous and arterial hemostasis.
  Steven J Grzegorski, Yakun Zhao, Catherine E Richter, Chia-Jui Ku, Kari I Lavik, Divyani Paul, James H Morrissey, Jordan A Shavit> ;Plos Genetics. 2022 Nov 1
• 103 citations
  Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease.
  Wei Zhou, Masahiro Kanai, Kuan-Han H Wu, Humaira Rasheed, Kristin Tsuo, Jibril B Hirbo, Ying Wang, Arjun Bhattacharya, Huiling Zhao, Shinichi Namba, Ida Surakka, Brook...> ;Cell Genomics. 2022 Oct 12
• 3 citations
  Nuclear Progestin Receptor-mediated Linkage of Blood Coagulation and Ovulation.
  Jing Huang, Chao Sun, Dong Teng Liu, Nan Nan Zhao, Jordan A Shavit, Yong Zhu, Shi Xi Chen> ;Endocrinology. 2022 Jul 1
• Fishing for answers to hemostatic and thrombotic disease: Genome editing in zebrafish.
  Azhwar Raghunath, Allison C Ferguson, Jordan A Shavit> ;Research and Practice in Thrombosis and Haemostasis. 2022 Jul 1
• 3 citations
  Phage display broadly identifies inhibitor-reactive regions in von Willebrand factor.
  Andrew Yee, Manhong Dai, Stacy E. Croteau, Jordan A. Shavit, Steven W. Pipe, David R. Siemieniak, Fan Meng, David W. Ginsburg> ;Journal of Thrombosis and Haemostasis. 2021 Jul 13
• 2 citations
  Acitretin mitigates uroporphyrin-induced bone defects in congenital erythropoietic porphyria models
  Juliana Bragazzi Cunha, Dhiman Maitra, Ning Kuo, Rodrigo Azuero-Dajud, Allison C. Ferguson, Megan S. Griffin, Stephen I. Lentz, Jordan A. Shavit, M. Bishr Omary, Jared...> ;Scientific Reports. 2021 May 5
• 5 citations
  Novel treatments for hemophilia through rebalancing of the coagulation cascade.
  Yakun Zhao, Angela C. Weyand, Jordan A. Shavit> ;Pediatric Blood & Cancer. 2021 Feb 12
• 6 citations
  A genetic modifier of venous thrombosis in zebrafish reveals a functional role for fibrinogen AαE in early hemostasis
  Cristina Freire, Richard J. Fish, Rui Vilar, Corinne Di Sanza, Steven J. Grzegorski, Catherine E. Richter, Jordan A. Shavit, Marguerite Neerman-Arbez> ;Blood Advances. 2020 Nov 10
• 5 citations
  Otx2b mutant zebrafish have pituitary, eye and mandible defects that model mammalian disease
  Hironori Bando, Peter Gergics, Kevin Toolan, Catherine E. Richter, Jordan A. Shavit, Sally A. Camper> ;Human Molecular Genetics. 2020 Jun 27
• 8 citations
  Disruption of the kringle 1 domain of prothrombin leads to late onset mortality in zebrafish.
  Steven J. Grzegorski, Zhilian Hu, Yang Liu, Xinge Yu, Allison C. Ferguson, Hasam Madarati, Alexander P. Friedmann, Deepak Reyon, Paul Y. Kim, Colin A. Kretz, J. Keith ...> ;Scientific Reports. 2020 Mar 4
• 47 citations
  Effects of MYBPC3 loss-of-function mutations preceding hypertrophic cardiomyopathy.
  Adam S. Helms, Vi T. Tang, Thomas S. O’Leary, Sabrina Friedline, Mick Wauchope, Akul Arora, Aaron H Wasserman, Eric D. Smith, Lap Man Lee, Xiaoquan Wen, Jordan A Shavi...> ;JCI Insight. 2020 Jan 30
• 25 citations
  Efficacy of emicizumab in a pediatric patient with type 3 von Willebrand disease and alloantibodies
  Angela C. Weyand, Veronica H. Flood, Jordan A. Shavit, Steven W. Pipe> ;Blood Advances. 2019 Sep 24
• 4 citations
  Genome-wide linkage analysis and whole-exome sequencing identifies an ITGA2B mutation in a family with thrombocytopenia.
  Rami Khoriaty, Ayse Bilge Ozel, Shweta Ramdas, Charles W. Ross, Karl C. Desch, Jordan A. Shavit, Lesley Everett, David R. Siemieniak, Jun Li, David Ginsburg> ;British Journal of Haematology. 2019 May 23
• 17 citations
  Thrombocyte Inhibition Restores Protective Immunity to Mycobacterial Infection in Zebrafish.
  Elinor Hortle, Khelsey E Johnson, Matt D. Johansen, Tuong Nguyen, Jordan A. Shavit, Warwick J. Britton, David M. Tobin, Stefan H. Oehlers> ;The Journal of Infectious Diseases. 2019 Jul 2
• 35 citations
  Porphyrin-Induced Protein Oxidation and Aggregation as a Mechanism of Porphyria-Associated Cell Injury
  Dhiman Maitra, Juliana Bragazzi Cunha, Herbert L. Bonkovsky, Jordan A. Shavit, M. Bishr Omary, Jared S. Elenbaas> ;Cellular and Molecular Gastroenterology and Hepatology. 2019 Jan 1
• 15 citations
  Analysis of factor V in zebrafish demonstrates minimal levels needed for early hemostasis
  Angela C. Weyand, Steve J. Grzegorski, Megan S. Rost, Kari I. Lavik, Allison C. Ferguson, Marzia Menegatti, Catherine E. Richter, Rosanna Asselta, Stefano Duga, Flora ...> ;Blood Advances. 2019 Jun 11
• 8 citations
  Emicizumab prophylaxis to facilitate anticoagulant therapy for management of intra-atrial thrombosis in severe haemophilia with an inhibitor.
  Angela C. Weyand, Adam L. Dorfman, Jordan A. Shavit, Steven W. Pipe> ;Haemophilia. 2019 May 1
• 10 citations
  Zebrafish otolith biomineralization requires polyketide synthase.
  Kevin Thiessen, Steven J. Grzegorski, Yvonne Chin, Lisa N. Higuchi, Christopher J. Wilkinson, Jordan A. Shavit, Kenneth L. Kramer> ;Mechanisms of Development. 2019 Jun 1
• 9 citations
  Loss of fibrinogen in zebrafish results in an asymptomatic embryonic hemostatic defect and synthetic lethality with thrombocytopenia.
  Zhilian Hu, Kari I. Lavik, Yang Liu, Andy H. Vo, Catherine E. Richter, Jorge Di Paola, Jordan A. Shavit> ;Journal of Thrombosis and Haemostasis. 2019 Feb 25
• 49 citations
  Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo.
  Rami Khoriaty, Geoffrey G. Hesketh, Amélie Bernard, Angela C. Weyand, Dattatreya Mellacheruvu, Guojing Zhu, Mark J. Hoenerhoff, Beth McGee, Lesley Everett, Elizabeth J...> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 Jul 31
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Journal Articles

• Functions of the COPII Gene Paralogs SEC23A and SEC23B Are Interchangeable in Vivo  
  Rami Khoriaty, Lesley Everett, Jordan A Shavit, Angela C Weyand, David Ginsburg, Proceedings of the National Academy of Sciences
• Biobank-Driven Genomic Discovery Yields New Insight into Atrial Fibrillation Biology  
  Frederick E Dewey, Jordan A Shavit, Chad M Brummett, Michael R Mathis, Sachin Kheterpal, Nature

Abstracts/Posters

• Genetic Duplication of Tissue Factor Leads to Partial Specialization of Function in Zebrafish
  Jordan A. Shavit, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Lectures

• Filling a Clinical Void: Engineering Platelets In Vitro 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Special Symposium on the Basic Science of Hemostasis and Thrombosis 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Thrombopoiesis Revised: From Lung to Hematopoietic Stem Cell Platelet Bias 
  60th American Society of Hematology Annual Meeting - 12/2/2018
• Thrombopoiesis Revised: From Lung to Hematopoietic Stem Cell Platelet Bias 
  60th American Society of Hematology Annual Meeting - 12/2/2018
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