KhaledArefHassanMDMS

PubMed

• MUC1-C: The Occam Razor of Osimertinib Resistance?
  Anirudh Yalamanchali, Khaled A Hassan> ;Journal of Thoracic Oncology. 2024 Mar 1
• 2 citations
  Clinical Outcomes With Pembrolizumab-Based Therapies in Recurrent/Refractory NSCLC After Chemoradiation and Consolidative Durvalumab.
  Lukas Delasos, Wei Wei, Khaled A Hassan, Nathan A Pennell, Pradnya Patil, James Stevenson> ;Clinical Lung Cancer. 2023 Sep 1
• 20 citations
  Bone Metastases, Skeletal-Related Events, and Survival in Patients With Metastatic Non-Small Cell Lung Cancer Treated With Immune Checkpoint Inhibitors.
  Angel Qin, Songzhu Zhao, Abdul Miah, Lai Wei, Sandipkumar Patel, Andrew Johns, Madison Grogan, Erin M. Bertino, Kai He, Peter G. Shields, Gregory P. Kalemkerian, Shiri...> ;Journal of the National Comprehensive Cancer Network. 2021 Apr 20
• 13 citations
  A Pilot Study of Atezolizumab Plus Hypofractionated Image Guided Radiation Therapy for the Treatment of Advanced Non-Small Cell Lung Cancer.
  Angel Qin, Ramesh Rengan, Sylvia Lee, Rafael Santana-Davila, Bernardo H. L. Goulart, Renato G. Martins, Christina S. Baik, Gregory P. Kalemkerian, Khaled A. Hassan, Br...> ;International Journal of Radiation Oncology, Biology, Physics. 2020 Sep 1
• 50 citations
  High-Throughput Label-Free Isolation of Heterogeneous Circulating Tumor Cells and CTC Clusters from Non-Small-Cell Lung Cancer Patients.
  Mina Zeinali, Maggie Lee, Arthi Nadhan, Anvya Mathur, Casey Hedman, Eric Lin, Ramdane Harouaka, Max S. Wicha, Lili Zhao, Nallasivam Palanisamy, Mathias Hafner, Rishind...> ;Cancers. 2020 Jan 3
• 61 citations
  Primary tumor-induced immunity eradicates disseminated tumor cells in syngeneic mouse model
  Raziye Piranlioglu, Eunmi Lee, Maria Ouzounova, Roni J. Bollag, Alicia Vinyard, Ali S. Arbab, Daniela Marasco, Mustafa Guzel, John K. Cowell, Muthusamy Thangaraju, Ahm...> ;Nature Communications. 2019 Mar 29
• Dietary myo-inositol chemoprevents lung carcinogenesis via boosting immune system in Kras mouse model.
  Piranlioglu, R.,Korkaya, H.,Hassan, K. A.> ;J Thorac Dis. 2019 Apr 26
• The EGFR T790M mutation is acquired through AICDA-mediated deamination of 5-methylcytosine following TKI treatment in lung cancer.
  El Kadi, N.,Wang, L.,Davis, A.,Korkaya, H.,Cooke, A.,Vadnala, V.,Brown, N. A.,Betz, B. L.,Cascalho, M.,Kalemkerian, G. P.,Hassan, K. A.> ;Cancer Res.. 1900 Jan 01
• 3 citations
  Small cell lung cancer heterogeneity: elevated a Notch above the Rest !
  Khaled A. Hassan> ;Journal of Thoracic Disease. 2018 Feb 1
• 96 citations
  Notch Reporter Activity in Breast Cancer Cell Lines Identifies a Subset of Cells with Stem Cell Activity
  Rosemarie C. D'Angelo, Maria Ouzounova, April Davis, Daejin Choi, Stevie M. Tchuenkam, Gwangil Kim, Tahra Luther, Ahmed A. Quraishi, Yasin Senbabaoglu, Sarah J. Conley...> ;Molecular Cancer Therapeutics. 2015 Mar 1
• Lung cancer stem cell: fancy conceptual model of tumor biology or cornerstone of a forthcoming therapeutic breakthrough?
  Sourisseau, T.,Hassan, K. A.,Wistuba, I.,Penault-Llorca, F.,Adam, J.,Deutsch, E.,Soria, J. C.> ;J Thorac Oncol. 2013 Dec 19
• Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.
  Hassan, K. A.,Wang, L.,Korkaya, H.,Chen, G.,Maillard, I.,Beer, D. G.,Kalemkerian, G. P.,Wicha, M. S.> ;Clin. Cancer Res.. 2013 Apr 15
• Activation of an IL6 Inflammatory Loop Mediates Trastuzumab Resistance in HER2+ Breast Cancer by Expanding the Cancer Stem Cell Population.
  Korkaya, H., Kim, G. I., Davis, A., Malik, F., Henry, N. L., Ithimakin, S., Quraishi, A. A., Tawakkol, N., D'Angelo, R., Paulson, A. K., Chung, S., Luther, T., Paholak...> ;Mol Cell. 2012 Aug 24
• Changes in global function and regional ventilation and perfusion on SPECT during the course of radiotherapy in patients with non-small-cell lung cancer.
  Yuan ST Frey KA Gross MD Hayman JA Arenberg D Cai XW Ramnath N Hassan K Moran J Eisbruch A Ten Haken RK Kong FM> ;Int J Radiat Oncol Biol Phys. 2012 Mar 15
• An embryonic stem cell-like signature identifies poorly differentiated lung adenocarcinoma but not squamous cell carcinoma.
  Hassan KA Chen G Kalemkerian GP Wicha MS Beer DG> ;Clin Cancer Res. 2009 Oct 15
• 12 citations
  Long-term survival in paraneoplastic opsoclonus-myoclonus syndrome associated with small cell lung cancer.
  Khaled A. Hassan, Gregory P. Kalemkerian, Jonathan D Trobe> ;Journal of Neuro-Ophthalmology. 2008 Mar 1
• 29 citations
  Abnormal DNA repair in selenium-treated human cells.
  Khaled S. Abul-Hassan, Bruce E. Lehnert, Lorraine Guant, Richard M. Walmsley> ;Mutation Research. 2004 Dec 31
• Effects of insulin-like growth factor binding protein-3 and farnesyltransferase inhibitor SCH66336 on Akt expression and apoptosis in non-small-cell lung cancer cells.
  Lee H, Moon H, Chun K, Chang Y, Hassan K, Ji L, Lotan R, Khuri FR, Hong WK> ;J. Natl. Cancer Inst.. 2004-10-20
• Loss of Fhit expression in head and neck squamous cell carcinoma and its potential clinical implication.
  Tai SK Lee JI Ang KK El-Naggar AK Hassan KA Liu D Lee JJ Ren H Hong WK Mao L> ;Clin Cancer Res. 2004 Aug 15
• Hypermethylation of the retinoic acid receptor-beta(2) gene in head and neck carcinogenesis.
  Youssef EM, Lotan D, Issa J, Wakasa K, Fan Y, Mao L, Hassan K, Feng L, Lee JJ, Lippman SM, Hong WK, Lotan R> ;Clin. Cancer Res.. 2004-03-01
• 45 citations
  Implication of Protein Kinase B/Akt and Bcl-2/Bcl-XL Suppression by the Farnesyl Transferase Inhibitor SCH66336 in Apoptosis Induction in Squamous Carcinoma Cells
  Kyung Hee Chun, Ho-Young Lee, Khaled A. Hassan, Fadlo R. Khuri, Waun Ki Hong, Reuben Lotan> ;Cancer Research. 2003 Aug 15
• 76 citations
  Cyclin B1 overexpression and resistance to radiotherapy in head and neck squamous cell carcinoma.
  Khaled A. Hassan, K. Kian Ang, Adel K. El-Naggar, Michael D. Story, Janet I. Lee, Diane Liu, Waun Ki Hong, Li Mao> ;Cancer Research. 2002 Nov 15
• 19 citations
  Inhibition of oncogenic K-ras signaling by aerosolized gene delivery in a mouse model of human lung cancer.
  Ho-Young Lee, Young Ah Suh, Janet I. Lee, Khaled A. Hassan, Li Mao, Thomas Force, Brian E. Gilbert, Tyler Jacks, Jonathan M. Kurie> ;Clinical Cancer Research. 2002 Sep 1
• Loss of PTEN expression as a prognostic marker for tongue cancer.
  Lee JI, Soria JC, Hassan KA, El-Naggar AK, Tang X, Liu DD, Hong WK, Mao L> ;Arch. Otolaryngol. Head Neck Surg.. 2001-12-01
• Activation of melanoma antigen tumor antigens occurs early in lung carcinogenesis.
  Jang SJ, Soria JC, Wang L, Hassan KA, Morice RC, Walsh GL, Hong WK, Mao L> ;Cancer Res.. 2001-11-01
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Journal Articles

• The EGFR T790M Mutation Is Acquired Through AICDA-Mediated Deamination of 5-Methylcytosine Following TKI Treatment in Lung Cancer  
  Gregory P Kalemkerian, Khaled A Hassan, Clinical Cancer Research