KlineBoltonMD

Nephrology • Charlottesville, VA

Chronic Renal Failure & Dialysis, Glomerular Disease

Professor, Internal Medicine, University of Virginia School of Medicine

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Office
1215 Lee St
Fl 3
Charlottesville, VA 22908
Phone+1 434-924-8129

Fax+1 434-972-4266
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Education & Training

University of ChicagoResidency, Internal Medicine, 1971 - 1973
Boston City Hospital - Harvard II & IV Service1969 - 1971
University of Virginia School of MedicineClass of 1969

Certifications & Licensure

VA State Medical License 1969 - 2024
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Nephrology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
CMS Meaningful Use Stage 1 Certification EpicCare Inpatient - Core EMR, Epic Systems Corporation, 2012
Elected Member The American Society for Clinical Investigation, 1985

Clinical Trials

Abdominal Compression Elastic Support (ACES) Start of enrollment: 2014 Jun 01
Completed
Not Applicable

Publications & Presentations

PubMed

13 citations
Oral ghrelin receptor agonist MK-0677 increases serum insulin-like growth factor 1 in hemodialysis patients: a randomized blinded study.
Garland A. Campbell, James T. Patrie, Bruce D. Gaylinn, Michael O. Thorner, Warren K. Bolton> ;Nephrology, Dialysis, Transplantation. 2018 Mar 1
Association of Plasma Des-Acyl Ghrelin Levels with CKD
Warren K Bolton, Michael O Thorner> ;Journal of the American Society of Nephrology. 2013 Jul
Referral and Comanagement of the Patient With CKD.
Campbell, G.A., Bolton, W.K.> ;Adv Chronic Kidney Dis. 2011 Nov
Editorial: Are men rats? Dendritic cells in autoimmune glomerulonephritis.
Sung, S.J., Bolton, W.K.> ;J Leukoc Biol. 2010 Nov
Phase 1 study of anti-CTGF monoclonal antibody in patients with diabetes and microalbuminuria.
Adler, S.G., Schwartz, S., Williams, M.E., Arauz-Pacheco, C., Bolton, W.K., Lee, T., Li, D., Neff, T.B., Urquilla, P.R., Sewell, K.L.> ;Clin J Am Soc Nephrol. 2010 Aug
Nephrogenic systemic fibrosis: a survey of nephrologists' perceptions and practices.
Abdel-Kader, K., Patel, P.R., Kallen, A.J., Sinkowitz-Cochran, R.L., Bolton, W.K., Unruh, M.L.> ;Clin J Am Soc Nephrol. 2010 Jun
Potential new therapeutic agents for diabetic kidney disease.
Turgut, F., Bolton, W.K.> ;Am J Kidney Dis. 2010 May
T cells and dendritic cells in glomerular disease: the new glomerulotubular feedback loop.
Sung, S., Bolton, W.K.> ;Kidney Int. 2010 Mar
39 citations
Epitope Spreading and Autoimmune Glomerulonephritis in Rats Induced by a T Cell Epitope of Goodpasture’s Antigen
Warren K. Bolton, Lanlin Chen, Thomas Hellmark, Jörgen Wieslander, Jay W. Fox> ;Journal of the American Society of Nephrology. 2005 Sep 1
Immunodominant epitopes of alpha3(IV)NC1 induce autoimmune glomerulonephritis in rats.
Chen, L., Hellmark, T., Wieslander, J., Bolton, W.K.> ;Kidney Int. 2003 Dec
Point mutations of single amino acids abolish ability of alpha3 NC1 domain to elicit experimental autoimmune glomerulonephritis in rats.
Hellmark, T., Chen, L., Ohlsson, S., Wieslander, J., Bolton, W.K.> ;J Biol Chem. 2003 Nov 21
3 citations
Connecting the dots: caring for the patient with progressive CKD.
Warren K. Bolton> ;Nephrology News & Issues. 2003 May 1
2 citations
Isolation and characterization of chicken mesangial cells.
Marc J. Sadovnic, Jessica Brand-Elnaggar, Kline Bolton> ;Nephron. 1991 Jan 1
74 citations
Methylprednisolone therapy for acute crescentic rapidly progressive glomerulonephritis.
Kline Bolton, Benjamin C. Sturgill> ;American Journal of Nephrology. 1989 Jan 1
6 citations
Nephrotic Syndrome and Focal Glomerular Sclerosis in Aging Man
Kline Bolton, Frederic B. Westervelt, Benjamin C. Sturgill> ;Nephron. 1978 Jan 1
Simian T cell leukemia virus type I from naturally infected feral monkeys from central and west Africa encodes a 91-amino acid p12 (ORF-I) protein as opposed to a 99-a...
Saksena, N. K., Srinivasan, A., Ge, Y. C., Xiang, S. H., Azad, A., Bolton, W., Herve, V., Reddy, S., Diop, O., Miranda-Saksena, M., Rawlinson, W. D., Vandamme, A. M., ...> ;AIDS Res Hum Retroviruses. 1997 Mar 20
Pharmacokinetics of moxalactam in subjects with various degrees of renal dysfunction.
Bolton, W. K., Scheld, W. M., Spyker, D. A., Overby, T. L., Sande, M. A.> ;Antimicrob Agents Chemother. 1980 Dec
New avian model of experimental glomerulonephritis consistent with mediation by cellular immunity. Nonhumorally mediated glomerulonephritis in chickens.
Bolton, W. K., Tucker, F. L., Sturgill, B. C.> ;J Clin Invest. 1984 May
Rapidly progressive silicon nephropathy.
Bolton, W. K., Suratt, P. M., Strugill, B. C.> ;Am J Med. 1981 Nov
Reversible renal failure from isolated granulomatous renal sarcoidosis.
Bolton, W. K., Atuk, N. O., Rametta, C., Sturgill, B. C., Spargo, B. H.> ;Clin Nephrol. 1976 Feb
Pharmacokinetics of aztreonam in patients with various degrees of renal dysfunction.
Mihindu, J. C., Scheld, W. M., Bolton, N. D., Spyker, D. A., Swabb, E. A., Bolton, W. K.> ;Antimicrob Agents Chemother. 1983 Aug
Comparison of alternate day steroids and daily steroids in renal transplant recipients.
Davisson, N. A., Westervelt, F. B., Bolton, W. K.> ;Proc Clin Dial Transplant Forum. 1980
New technique of kidney tissue processing for immunofluorescence microscopy: formol sucrose/gum sucrose/paraffin.
Bolton, W. K., Mesnard, R. M.> ;Lab Invest. 1982 Aug
Iatrogenic renal disease.
Sturgill, B. C., Bolton, W. K.> ;Pathol Annu. 1985 Jan 01
Chronic autologous immune complex glomerulopathy: effect of cyproheptadine.
Bolton, W. K., Spargo, B. A., Lewis, E. J.> ;J Lab Clin Med. 1974 May 01
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Grant Support

Experimental Autoimmune Nephritis: Epitope Spreading In Pathogenesis And ControlNational Institute Of Diabetes And Digestive And Kidney Diseases2008–2011
Growth Hormone Secretagogue MK-677 Therapy Effect On IGF-1 Levels In CKD &EsrdNational Center For Research Resources2008–2009
Growth Hormone Secretagogue MK-677 Therapy In CKD And ESRDNational Institute Of Diabetes And Digestive And Kidney Diseases2007–2008
Assessment Of Ghrelin Levels In END Stage Renal Disease (ESRD)National Center For Research Resources2006
Assessment Of Ghrelin Levels In Chronic Kidney DiseaseNational Center For Research Resources2004–2005
Donepezil Hydrochloride (ARICEPT) PharmacokineticsNational Center For Research Resources2000–2002
Nephritogenic Epitopes In Goodpastures SyndromeNational Institute Of Diabetes And Digestive And Kidney Diseases1999–2001
Placebo Controlled Safety And Efficacy Of Aminoguanidine In Diabetic PatientsNational Center For Research Resources1995–2000
Auriculin Anaritide In The Treatment Of Oliguric Acute Tubular NecrosisNational Center For Research Resources1997
Cell Mediated Glomerulonephritis In A New ModelNational Institute Of Diabetes And Digestive And Kidney Diseases1991–1994
Dynamics Of Endogenous Gonadotropin Secretion In Renal FailureNational Center For Research Resources1991–1992
Diabetic Kidney Study--Enalapril In Type II Diabetics With HypertensionNational Center For Research Resources1990–1992
Diabetic Kidney Study--Enalapril In Diabetics With HypertensionNational Center For Research Resources1988–1989
Study Of Experimental Autoimmune NephritisNational Institute Of Diabetes And Digestive And Kidney Diseases1986–1988
Cefoperazone And Sulbactam Therapy In END State Renal DiseaseNational Center For Research Resources1986
Study Of Experimental Autoimmune In ChickensNat Inst Of Arthritis, Diabetes, Digestive &Kidney Diseases1985