KristinaHoot(Hoot)YoungMD

PubMed

• 3 citations
  Tumor resident memory CD8 T cells and concomitant tumor immunity develop independently of CD4 help.
  Terry R Medler, Gwen Kramer, Shelly Bambina, Andrew J Gunderson, Alejandro Alice, Tiffany Blair, Lauren Zebertavage, Thomas Duhen, Rebekka Duhen, Kristina Young, Marka...> ;Scientific Reports. 2023 Apr 18
• Angiotensin receptor blockade and stereotactic body radiation therapy for early stage lung cancer ARB & SBRT for early stage lung cancer.
  Lauren T Maloney, Emile Latour, Yiyi Chen, Douglas Rice, Alison Grossblatt-Wait, Nima Nabavizadeh, Charles R Thomas, Kristina H Young, Joshua M Walker, John Holland, A...> ;Cancer Biology & Therapy. 2022 Dec 31
• 24 citations
  Galunisertib plus neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer: a single-arm, phase 2 trial.
  Tomoko Yamazaki, Andrew J Gunderson, Miranda Gilchrist, Mark Whiteford, Maria X Kiely, Amanda Hayman, David O'Brien, Rehan Ahmad, Jeffrey V Manchio, Nathaniel Fox, Kay...> ;The Lancet. Oncology. 2022 Sep 1
• 4 citations
  Effects of radiation on tumor vasculature.
  Tomoko Yamazaki, Kristina H Young> ;Molecular Carcinogenesis. 2021 Oct 13
• 63 citations
  Neoadjuvant immunoradiotherapy results in high rate of complete pathological response and clinical to pathological downstaging in locally advanced head and neck squamo...
  Rom Leidner, Marka R. Crittenden, Kristina H. Young, Hong Xiao, Yaping Wu, Marcus Couey, Ashish A. Patel, Allen C. Cheng, Amber L. Watters, Carlo Bifulco, George Morri...> ;Journal for Immunotherapy of Cancer. 2021 May 1
• 65 citations
  Germinal center reactions in tertiary lymphoid structures associate with neoantigen burden, humoral immunity and long-term survivorship in pancreatic cancer
  Andrew J. Gunderson, Venkatesh Rajamanickam, Cynthia Bui, Brady Bernard, Joanna Pucilowska, Carmen Ballesteros-Merino, Mark Schmidt, Kayla McCarty, Michaela Philips, B...> ;Oncoimmunology. 2021 Mar 17
• 9 citations
  Transoral robotic surgery and neck dissection for HPV-positive oropharyngeal carcinoma: Importance of nodal count in survival
  Chi T. Viet, Eric J. Dierks, Allen C. Cheng, Ashish A. Patel, Shu-Ching Chang, Marcus Couey, Amber L. Watters, Thien Hoang, Hong D. Xiao, Marka R. Crittenden, Rom Leid...> ;Oral Oncology. 2020 Oct 1
• 7 citations
  Transcriptional and immunohistological assessment of immune infiltration in pancreatic cancer.
  Brady Bernard, Venkatesh Rajamanickam, Christopher Dubay, Brian D. Piening, Emilio Alonso, Zeljka Jutric, Ephraim Tang, Pippa Newell, Paul D. Hansen, Terry R. Medler, ...> ;Plos One. 2020 Aug 31
• 99 citations
  TGFβ suppresses CD8+ T cell expression of CXCR3 and tumor trafficking.
  Andrew J. Gunderson, Tomoko Yamazaki, Kayla McCarty, Nathaniel E Fox, Michaela Phillips, Alejandro F Alice, Tiffany C. Blair, Mark H. Whiteford, David P. O'Brien, Reha...> ;Nature Communications. 2020 Apr 9
• 8 citations
  Using Preclinical Data to Design Combination Clinical Trials of Radiation Therapy and Immunotherapy
  Michael J. Gough, Shay Sharon, Marka R. Crittenden, Kristina H. Young> ;Seminars in Radiation Oncology. 2020 Apr 1
• 30 citations
  Effects of Radiation on the Tumor Microenvironment.
  Arta M. Monjazeb, Kurt A. Schalper, Franz Villarroel-Espindola, Anthony T. Nguyen, Stephen L. Shiao, Kristina H. Young> ;Seminars in Radiation Oncology. 2020 Apr 1
• 47 citations
  Blockade of fibroblast activation protein in combination with radiation treatment in murine models of pancreatic adenocarcinoma.
  Andrew J. Gunderson, Tomoko Yamazaki, Kayla McCarty, Michaela Phillips, Alejandro F Alice, Shelly Bambina, Lauren Zebertavage, David Friedman, Benjamin Cottam, Pippa N...> ;Plos One. 2019 Feb 6
• 24 citations
  Exploring optimal sequencing of radiation and immunotherapy combinations.
  Andrew J. Gunderson, Kristina H. Young> ;Advances in Radiation Oncology. 2018 Oct 1
• 1 citations
  Correction: STING expression and response to treatment with STING ligands in premalignant and malignant disease.
  Jason R Baird, Zipei Feng, Hong D Xiao, David Friedman, Ben Cottam, Bernard A Fox, Gwen Kramer, Rom S Leidner, R Bryan Bell, Kristina H Young, Marka R Crittenden, Mich...> ;Plos One. 2018 Jan 1
• 44 citations
  Programmed cell death-1 blockade enhances response to stereotactic radiation in an orthotopic murine model of hepatocellular carcinoma
  David Friedman, Jason R. Baird, Kristina H. Young, Benjamin Cottam, Marka R. Crittenden, Scott L. Friedman, Michael J. Gough, Pippa Newell> ;Hepatology Research. 2017 Jun 1
• 41 citations
  Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model.
  Gwendolyn J. McGinnis, David Friedman, Kristina H. Young, Eileen Ruth S. Torres, Charles R. Thomas, Michael J. Gough, Jacob Raber> ;Oncotarget. 2017 Feb 7
• 9 citations
  STING expression and response to treatment with STING ligands in premalignant and malignant disease.
  Jason R Baird, Zipei Feng, Hong D Xiao, David Friedman, Ben Cottam, Bernard A Fox, Gwen Kramer, Rom S Leidner, R Bryan Bell, Kristina H Young, Marka R Crittenden, Mich...> ;Plos One. 2017 Jan 1
• 68 citations
  Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy
  Marka R. Crittenden, Jason R. Baird, David J. Friedman, Talicia Savage, Lauren Uhde, Alejandro F Alice, Benjamin Cottam, Kristina H. Young, Pippa Newell, Cynthia Nguye...> ;Oncotarget. 2016 Sep 2
• 74 citations
  A hypofractionated radiation regimen avoids the lymphopenia associated with neoadjuvant chemoradiation therapy of borderline resectable and locally advanced pancreatic...
  Todd S. Crocenzi, Benjamin Cottam, Pippa Newell, Ronald F. Wolf, Paul D. Hansen, Chet W. Hammill, Matthew C. Solhjem, Yue-Yun To, Amy Greathouse, Garth W. Tormoen, Zel...> ;Journal for Immunotherapy of Cancer. 2016 Aug 16
• 217 citations
  Optimizing Timing of Immunotherapy Improves Control of Tumors by Hypofractionated Radiation Therapy.
  Kristina H. Young, Jason R. Baird, Talicia Savage, Benjamin Cottam, David J. Friedman, Shelly Bambina, David J. Messenheimer, Bernard A. Fox, Pippa Newell, Keith S. Ba...> ;Plos One. 2016 Jun 9
• 10 citations
  Comparing equals when evaluating immunotherapy with different doses and fractions of radiation therapy
  Michael J. Gough, Marka R. Crittenden, Kristina H. Young> ;Immunotherapy. 2015 Aug 13
• 8 citations
  Tumor immune remodeling by TGFβ inhibition improves the efficacy of radiation therapy
  Kristina H. Young, Michael J. Gough, Marka R. Crittenden> ;Oncoimmunology. 2015 Apr 2
• 42 citations
  TGFβ inhibition prior to hypofractionated radiation enhances efficacy in preclinical models.
  Kristina H. Young, Pippa Newell, Benjamin Cottam, David J. Friedman, Talicia Savage, Jason R. Baird, Emmanuel T. Akporiaye, Michael J. Gough, Marka R. Crittenden> ;Cancer Immunology Research. 2014 Jul 21
• 34 citations
  Expression of Arginase I in Myeloid Cells Limits Control of Residual Disease after Radiation Therapy of Tumors in Mice
  Marka R. Crittenden, Talicia Savage, Benjamin Cottam, Jason R. Baird, Paulo C. Rodriguez, Pippa Newell, Kristina H. Young, Andrew Jackson, Michael J. Gough> ;Radiation Research. 2014 Jul 3
• 1 citations
  Heavy PETting: reducing radiation exposure from intradepartment positron emission tomography scans.
  Sophia Bornstein, Kristina H. Young, J. Tanyi, John M. Holland> ;International Journal of Radiation Oncology, Biology, Physics. 2014 Mar 1
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