LanZhouMD

PubMed

• The ESCRT protein CHMP5 promotes T cell leukemia by controlling BRD4-p300-dependent transcription.
  Umphred-Wilson, K., Ratnayake, S., Tang, Q., Wang, R., Devaiah, B., Chen, Q., Meerzaman, D., Singer, D., Adoro, S., Zhou, L.> ;Biorxiv. 2024 Jan 31
• Loss of GSK3β in hematopoietic stem cells results in normal hematopoiesis in mice.
  Grace Lee, Jude Franklin, Kalpana Gupta, Ruifu Liu, Lan Zhou, Christopher Ryder, Lukasz Sobieraj, Luke Molitor, Olubukola Abiona, Howard Meyerson, Indrani Das, Zachary...> ;Blood Advances. 2023 Dec 12
• Loss of HES1 expression is associated with extracellular matrix remodeling and tumor immune suppression in KRAS mutant colon adenocarcinomas.
  Lei Wang, Wenchao Gu, Bingqing Zou, Matthew Kalady, Wei Xin, Lan Zhou> ;Scientific Reports. 2023 Sep 25
• 1 citations
  Late Recurrence of Colorectal Carcinoma in Patients with Malignant Polyp and Risk Factors.
  Min Cui, Navid Sadri, Amad Awadallah, Lan Zhou, Wei Xin> ;International Journal of Surgical Pathology. 2023 Sep 1
• 1 citations
  Organoids as a Model System for Studying Notch Signaling in Intestinal Epithelial Homeostasis and Intestinal Cancer.
  Yingtong Dou, Theresa Pizarro, Lan Zhou> ;The American Journal of Pathology. 2022 Oct 1
• 11 citations
  Targeting CRABP-II overcomes pancreatic cancer drug resistance by reversing lipid raft cholesterol accumulation and AKT survival signaling.
  Shuiliang Yu, Lei Wang, Danian Che, Mei Zhang, Ming Li, Mikihiko Naito, Wei Xin, Lan Zhou> ;Journal of Experimental & Clinical Cancer Research. 2022 Mar 8
• 2 citations
  Endothelial PERK-ATF4-JAG1 axis activated by T-ALL remodels bone marrow vascular niche.
  Cui Liu, Qiuyun Chen, Yinghui Shang, Lechuang Chen, Jay Myers, Amad Awadallah, Jinger Sun, Shuiliang Yu, Katharine Umphred-Wilson, Danian Che, Yingtong Dou, Luoyi Li, ...> ;Theranostics. 2022 Jan 1
• 13 citations
  Notch-Regulated Dendritic Cells Restrain Inflammation-Associated Colorectal Carcinogenesis.
  Lei Wang, Shuiliang Yu, Ernest R. Chan, Kai-Yuan Chen, Cui Liu, Danian Che, Amad Awadallah, Jay Myers, David Askew, Alex Yee-Chen Huang, Ivan Maillard, Dan Huang, Wei ...> ;Cancer Immunology Research. 2021 Mar 1
• Vascular thrombosis and vasculitis in the gastrointestinal tract are associated with poor prognosis in patients with COVID-19.
  Min Cui, Qiang Wang, Alison W Xin, Danian Che, Zhengbin Lu, Lan Zhou, Wei Xin> ;International Journal of Clinical and Experimental Pathology. 2021 Jan 1
• 1 citations
  O-Fucose and Fringe-modified NOTCH1 extracellular domain fragments as decoys to release niche-lodged hematopoietic progenitor cells
  Shuiliang Yu, Weihuan Wang, Marwah Albakri, Xiaoxing Yu, Gurnoor Majihail, Seunghwan Lim, Rachel K. LoPilato, Atsuko Ito, John J. Letterio, Robert S. Haltiwanger, Lan ...> ;Glycobiology. 2021 Jun 3
• 7 citations
  A Review of Advances in Hematopoietic Stem Cell Mobilization and the Potential Role of Notch2 Blockade
  Marwah Albakri, Hammad Tashkandi, Lan Zhou> ;Cell Transplantation. 2020 Aug 4
• 12 citations
  Peritumoral/vascular expression of PSMA as a diagnostic marker in hepatic lesions
  Wei Chen, Zhenghong Lee, Amad Awadallah, Lan Zhou, Wei Xin> ;Diagnostic Pathology. 2020 Jul 23
• Systemic Notch downregulation promotes KrasG12D‐induced myeloproliferative neoplasm
  Xiaona You, Zhi Wen, Yuan I. Chang, Erik A. Ranheim, Yun Zhou, Lan Zhou, Guangyao Kong, Jing Zhang> ;British Journal of Haematology. 2019 Mar 31
• 11 citations
  Downregulating Notch counteracts KrasG12D-induced ERK activation and oxidative phosphorylation in myeloproliferative neoplasm.
  Guangyao Kong, Xiaona You, Zhi Wen, Yuan I. Chang, Shuiming Qian, Erik A. Ranheim, Christopher Letson, Xinmin Zhang, Yun Zhou, Yangang Liu, Adhithi Rajagopalan, Jingfa...> ;Leukemia. 2019 Mar 1
• Kit-independent mast cell adhesion mediated by Notch.
  Akihiko Murata, Mari Hikosaka, Miya Yoshino, Lan Zhou, Shin-Ichi Hayashi> ;International Immunology. 2019 Feb 15
• 12 citations
  Comparison of targeted next generation sequencing (NGS) versus isolated BRAF V600E analysis in patients with metastatic melanoma.
  Meng Lei Zhu, Lan Zhou, Navid Sadri> ;Virchows Archiv. 2018 Jun 21
• 4 citations
  Osteoblast Sorting and Intracellular Staining of CXCL12.
  Weihuan Wang, Gurnoor Majihail, Cui Lui, Lan Zhou> ;Bio-Protocol. 2018 May 20
• NP30 stimulates Th17 differentiation through DC in Schistosomiasis Japonicum.
  Xu, L.,Xue, B.,Zhou, L.,Qiu, Z.,Zhang, X.,Xu, N.,Tang, Q.,Zhu, J.,Guan, X.,Feng, Z.> ;Parasite Immunol.. 2018 Mar 27
• 36 citations
  Notch2 blockade enhances hematopoietic stem cell mobilization and homing.
  Weihuan Wang, Shuiliang Yu, Jay Myers, Yiwei Wang, William W. Xin, Marwah Albakri, Alison W. Xin, Ming Li, Alex Yee-Chen Huang, Wei Xin, Christian W. Siebel, Hillard M...> ;Haematologica. 2017 Oct 1
• 1 citations
  CRABP-II enhances pancreatic cancer cell migration and invasion by stabilizing interleukin 8 expression.
  Shuiliang Yu, Neetha Parameswaran, Ming Li, Yiwei Wang, Mark W Jackson, Huiping Liu, Wei Xin, Lan Zhou> ;Oncotarget. 2017 Aug 8
• 39 citations
  Fucosylation Deficiency in Mice Leads to Colitis and Adenocarcinoma
  Yiwei Wang, Dan Huang, Kai-Yuan Chen, Min Cui, Weihuan Wang, Xiaoran Huang, Amad Awadellah, Qing Li, Ann Friedman, William W. Xin, Luca Di Martino, Fabio Cominelli, Al...> ;Gastroenterology. 2017 Jan 1
• 19 citations
  Cellular Prion Protein Mediates Pancreatic Cancer Cell Survival and Invasion through Association with and Enhanced Signaling of Notch1.
  Yiwei Wang, Shuiliang Yu, Dan Huang, Min Cui, Huankai Hu, Lihua Zhang, Weihuan Wang, Neetha Parameswaran, Mark W. Jackson, Barbara A. Osborne, Barbara Bedogni, Chaoyan...> ;The American Journal of Pathology. 2016 Nov 1
• 4 citations
  Evaluation of Quantitative Real-Time PCR as a Hepatitis C Virus Supplementary Test After RIBA Discontinuation
  Shunyou Gong, Christine L. Schmotzer, Lan Zhou> ;Journal of Clinical Laboratory Analysis. 2016 Sep 1
• 39 citations
  Aberrant Notch Signaling in the Bone Marrow Microenvironment of Acute Lymphoid Leukemia Suppresses Osteoblast-Mediated Support of Hematopoietic Niche Function
  Weihuan Wang, Grant Zimmerman, Xiaoran Huang, Shuiliang Yu, Jay Myers, Yiwei Wang, Stephen Moreton, Joseph Nthale, Amad Awadallah, Rose Beck, Wei Xin, David N. Wald, A...> ;Cancer Research. 2016 Mar 15
• Phosphorylation-dependent cleavage regulates von Hippel Lindau proteostasis and function.
  German, P.,Bai, S.,Liu, X. D.,Sun, M.,Zhou, L.,Kalra, S.,Zhang, X.,Minelli, R.,Scott, K. L.,Mills, G. B.,Jonasch, E.,Ding, Z.> ;Oncogene. 1900 Jan 01
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Journal Articles

• Downregulating Notch Counteracts KrasG12D-Induced ERK Activation and Oxidative Phosphorylation in Myeloproliferative Neoplasm  
  Erik A Ranheim, David Yang, Warren S Pear, Lan Zhou, Mignon Loh, Eric Padron, Elliot Stieglitz, Nature

Abstracts/Posters

• Leukemia-Associated HSC Vascular Niche Is Negatively Regulated By PERK of Unfolded Protein Response (UPR)
  Lan Zhou, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019