LaurenRhea(Mitchell)SchaffMD

PubMed

• Long-term Outcomes in Primary CNS Lymphoma After R-MVP and High-Dose Chemotherapy With Autologous Hematopoietic Stem Cell Transplant.
  Kate Elizabeth Therkelsen, Lauren R Schaff, Subhiksha Nandakumar, Antonio M P Omuro, Lisa M DeAngelis, Christian Grommes> ;Neurology. 2023 Aug 15
• 1 citations
  Preclinical and clinical evaluation of Buparlisib (BKM120) in recurrent/refractory Central Nervous System Lymphoma.
  Christian Grommes, Elena Pentsova, Lauren R Schaff, Craig P Nolan, Thomas Kaley, Anne S Reiner, Katherine S Panageas, Ingo K Mellinghoff> ;Leukemia & Lymphoma. 2023 Sep 1
• 2 citations
  Is more better? Increased doses of high dose methotrexate and addition of rituximab is associated with improved outcomes in a large primary CNS lymphoma cohort.
  Prakirthi Yerram, Samantha N Reiss, Lisa Modelevsky, Lauren Schaff, Anne S Reiner, Katherine S Panageas, Christian Grommes> ;Annals of Lymphoma. 2023 Feb 28
• 89 citations
  Glioblastoma and Other Primary Brain Malignancies in Adults: A Review.
  Lauren R Schaff, Ingo K Mellinghoff> ;JAMA. 2023 Feb 21
• 1 citations
  Dynamic Mutational Landscape of Cerebrospinal Fluid Circulating Tumor DNA and Predictors of Survival after Proton Craniospinal Irradiation for Leptomeningeal Metastases.
  N Ari Wijetunga, Alexander G Goglia, Nils Weinhold, Michael F Berger, Michael Cislo, Daniel S Higginson, Kiana Chabot, Ahmed M Osman, Lauren Schaff, Elena Pentsova, Al...> ;Clinical Cancer Research. 2023 Feb 16
• 3 citations
  Combination Olaparib and Temozolomide for the Treatment of Glioma: A Retrospective Case Series.
  Lauren R Schaff, Marina Kushnirsky, Andrew L Lin, Subhiksha Nandakumar, Christian Grommes, Alexandra Michelle Miller, Igor T Gavrilovic, Craig Nolan, Elena Pentsova, I...> ;Neurology. 2022 Oct 24
• 3 citations
  Routine use of low-dose glucarpidase following high-dose methotrexate in adult patients with CNS lymphoma: an open-label, multi-center phase I study.
  Lauren R Schaff, Mina Lobbous, Dean Carlow, Ryan Schofield, Igor T Gavrilovic, Alexandra M Miller, Jacqueline B Stone, Anna F Piotrowski, Ugur Sener, Anna Skakodub, Ed...> ;BMC Cancer. 2022 Jan 13
• 14 citations
  Update on Novel Therapeutics for Primary CNS Lymphoma.
  Lauren Schaff, Christian Grommes> ;Cancers. 2021 Oct 26
• 39 citations
  Primary Central Nervous System Lymphoma
  Lauren Schaff, Christian Grommes> ;Blood. 2021 Oct 26
• 12 citations
  DNA Repair Mechanisms and Therapeutic Targets in Glioma
  Kevin Elmore, Lauren Schaff> ;Current Oncology Reports. 2021 Jun 14
• 7 citations
  Prognostic value of [18F]FDG PET/CT in patients with CNS lymphoma receiving ibrutinib-based therapies.
  Simone Krebs, Audrey Mauguen, Onur Yildirim, Vaios Hatzoglou, Jasmine H. Francis, Lauren Schaff, Ingo K. Mellinghoff, Heiko Schöder, Christian Grommes> ;European Journal of Nuclear Medicine and Molecular Imaging. 2021 May 8
• 6 citations
  Primary central nervous system lymphoma: a narrative review of ongoing clinical trials and goals for future studies.
  Lauren Schaff, Prakash Ambady, Nancy D. Doolittle, Christian Grommes> ;Annals of Lymphoma. 2021 Mar 30
• 50 citations
  Clinical trial of proton craniospinal irradiation for leptomeningeal metastases.
  T. Jonathan Yang, N.A. Wijetunga, Josh Yamada, Suzanne L. Wolden, Michelle Mehallow, Debra A. Goldman, Zhigang Zhang, Robert J. Young, Mark G. Kris, Helena A. Yu, Andr...> ;Neuro-Oncology. 2021 Jan 30
• 2 citations
  Prognostic and radiographic correlates of a prospectively collected molecularly profiled cohort of IDH1/2-wildtype astrocytomas.
  Andrew L. Lin, Marc K. Rosenblum, Ingo K. Mellinghoff, Viviane Tabar, Shahiba Ogilvie, Lauren Schaff, Tzu-I Jonathan Yang, Robert J. Young, Barry S. Taylor, Philip Jon...> ;Brain Pathology. 2020 May 1
• 5 citations
  Central Nervous System Lymphoma: Approach to Diagnosis and Treatment
  Carlos Eduardo Silva Correia, Lauren Schaff, Christian Grommes> ;Cancer Journal. 2020 May 1
• 19 citations
  Characterization of MGMT and EGFR protein expression in glioblastoma and association with survival.
  Lauren Schaff, Dongyao Yan, Sheeno Thyparambil, Yuan Tian, Fabiola Cecchi, Marc K. Rosenblum, Anne S. Reiner, Katherine S. Panageas, Todd Hembrough, Andrew L. Lin> ;Journal of Neuro-Oncology. 2020 Jan 1
• 7 citations
  Malignant transformation of neurocutaneous melanosis (NCM) following immunosuppression.
  Lauren Schaff, Ashfaq A. Marghoob, Marc K. Rosenblum, Rina Meyer, Yasmin Khakoo> ;Pediatric Dermatology. 2019 Jul 1
• 28 citations
  Updates on Primary Central Nervous System Lymphoma
  Lauren Schaff, Christian Grommes> ;Current Oncology Reports. 2018 Feb 28
• Novel Considerations in the Approach to Glioblastoma.
  Lauren Schaff, Lisa M. DeAngelis> ;Journal of Oncology Practice. 2017 Oct 11
• 3 citations
  E-Mail Is an Effective Tool for Rapid Feedback in Acute Stroke:
  Sara K. Rostanski, Joshua Stillman, Lauren Schaff, Crismely A. Perdomo, Ava L. Liberman, Eliza C. Miller, Randolph S. Marshall, Joshua Z. Willey, Olajide Williams> ;The Neurohospitalist. 2017 Jan 17
• 8 citations
  Indications for Treatment: Is Observation or Chemotherapy Alone a Reasonable Approach in the Management of Low-Grade Gliomas?
  Lauren Schaff, Andrew B. Lassman> ;Seminars in Radiation Oncology. 2015 Jul 1
• Enhanced radiosensitivity of androgen-resistant prostate cancer: AZD1152-mediated Aurora kinase B inhibition.
  Niermann, K.J., Moretti, L., Giacalone, N.J., Sun, Y., Schleicher, S.M., Kopsombut, P., Mitchell, L.R., Kim, K.W., Lu, B.> ;Radiat Res. 2011 Apr
• Harnessing the cell death pathway for targeted cancer treatment.
  Speirs CK, Hwang M, Kim S, Li W, Chang S, Varki V, Mitchell L, Schleicher S, Lu B> ;Am J Cancer Res. 2011-01-01
• Combined Bcl-2/mammalian target of rapamycin inhibition leads to enhanced radiosensitization via induction of apoptosis and autophagy in non-small cell lung tumor xeno...
  Kim, K.W., Moretti, L., Mitchell, L.R., Jung, D.K., Lu, B.> ;Clin Cancer Res. 2009-10-01
• Chemoradiotherapy in locally advanced, unresectable non-small cell lung cancer.
  Mitchell, L. R., Albert, J. M., Lu, B.> ;Rev Recent Clin Trials. 2009 May 01
• Join now to see all

Abstracts/Posters

• Increased Number of High Dose Methotrexate Cycles and the Addition of Rituximab Is Associated with Better Outcomes in a Large Primary CNSL Cohort
  Lauren Schaff, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Phase Ib of Copanlisib in Combination with Ibrutinib in Recurrent/Refractory Primary CNS Lymphoma (PCNSL)
  Lauren Schaff, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019