LouisHPhilipsonMDPhD FACP(He/Him)

PubMed

• 1 citations
  Longitudinal Assessment of Pancreas Volume by MRI Predicts Progression to Stage 3 Type 1 Diabetes.
  Moore, D., Powers, A., John Virostko, Jordan J Wright, Jonathan M Williams, Melissa A Hilmes, Taylor M Triolo, Hali Broncucia, Liping Du, Hakmook Kang, Shreya Nallapar...> ;Diabetes Care. 2024 Mar 1
• A loss-of-function mutation in KCNJ11 causing sulfonylurea-sensitive diabetes in early adult life.
  Natascia Vedovato, Maria V Salguero, Siri Atma W Greeley, Christine H Yu, Louis H Philipson, Frances M Ashcroft> ;Diabetologia. 2024 May 1
• Noninsulinoma Pancreatogenous Hypoglycemia Syndrome in a Patient With 1p36 Deletion Syndrome.
  Elizabeth Diane Auckley, Marilyn Arosemena, Louis H Philipson> ;JCEM Case Reports. 2024 Feb 1
• 20 citations
  Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine.
  Deirdre K Tobias, Jordi Merino, Abrar Ahmad, Catherine Aiken, Jamie L Benham, Dhanasekaran Bodhini, Amy L Clark, Kevin Colclough, Rosa Corcoy, Sara J Cromer, Daisy Dua...> ;Nature Medicine. 2023 Oct 1
• First-Line Therapy for Type 2 Diabetes With Sodium-Glucose Cotransporter-2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists.
  Neda Laiteerapong, Jason Alexander, Louis Philipson, Aaron N Winn, Elbert S Huang> ;Annals of Internal Medicine. 2023 Apr 1
• 2 citations
  Insulin Deficiency From Insulin Gene Mutation Leads to Smaller Pancreas.
  Jordan J Wright, Jonathan M Williams, Lisa R Letourneau-Freiberg, Balamurugan Kandasamy, Demetra Reyes, Anastasia Gant Kanegusuku, Louis Philipson, Siri Atma W Greeley...> ;Diabetes Care. 2023 Apr 1
• Objective and Subjective Sleep Patterns in Adults With Maturity-Onset Diabetes of the Young (MODY).
  Marilyn Arosemena, Maria V Salguero, Rochelle N Naylor, Kristen Wroblewski, Esra Tasali, Louis H Philipson> ;Diabetes Care. 2023 Mar 1
• Acute Recurrent Pancreatitis in a Child With INS-Related Monogenic Diabetes and a Heterozygous Pathogenic CFTR Mutation.
  Rachel G Son, Balamurugan Kandasamy, Tiana Bowden, Ruba K Azzam, Scott A Oakes, Louis H Philipson, Siri Atma W Greeley> ;Journal of the Endocrine Society. 2023 Jan 6
• Stress and human health in diabetes: A report from the 19Chicago Biomedical Consortium symposium.
  Raghavendra G Mirmira, Rohit N Kulkarni, Pingwen Xu, Tina Drossos, Krista Varady, Kristen L Knutson, Sirimon Reutrakul, Pamela Martyn-Nemeth, Robert M Sargis, Amisha W...> ;Journal of Clinical and Translational Science. 2023 Jan 1
• 9 citations
  First-Line Therapy for Type 2 Diabetes With Sodium-Glucose Cotransporter-2 Inhibitors and Glucagon-Like Peptide-1 Receptor Agonists : A Cost-Effectiveness Study.
  Jin G Choi, Aaron N Winn, M Reza Skandari, Melissa I Franco, Erin M Staab, Jason Alexander, Wen Wan, Mengqi Zhu, Elbert S Huang, Louis Philipson, Neda Laiteerapong> ;Annals of Internal Medicine. 2022 Oct 1
• Variants influencing age at diagnosis of HNF1A-MODY.
  Agnieszka H Ludwig-Słomczyńska, Michał T Seweryn, Piotr Radkowski, Przemysław Kapusta, Julita Machlowska, Stepanka Pruhova, Daniela Gasperikova, Christine Bellanne-Cha...> ;Molecular Medicine. 2022 Sep 14
• 22 citations
  Benefit of Continuous Glucose Monitoring in Reducing Hypoglycemia Is Sustained Through 12 Months of Use Among Older Adults with Type 1 Diabetes.
  Kellee M Miller, Lauren G Kanapka, Michael R Rickels, Andrew J Ahmann, Grazia Aleppo, Lynn Ang, Anuj Bhargava, Bruce W Bode, Anders Carlson, Naomi S Chaytor, Gail Gann...> ;Diabetes Technology & Therapeutics. 2022 Jun 1
• 12 citations
  Precision diabetes: Lessons learned from maturity-onset diabetes of the young (MODY).
  Mustafa Tosur, Louis H Philipson> ;Journal of Diabetes Investigation. 2022 Sep 1
• 42 citations
  ADA/EASD Precision Medicine in Diabetes Initiative: An International Perspective and Future Vision for Precision Medicine in Diabetes.
  John J Nolan, Anna R Kahkoska, Zhila Semnani-Azad, Marie-France Hivert, Linong Ji, Viswanathan Mohan, Robert H Eckel, Louis H Philipson, Stephen S Rich, Chandra Gruber...> ;Diabetes Care. 2022 Feb 1
• 1 citations
  Integrated Analysis of the Pancreas and Islets Reveals Unexpected Findings in Human Male With Type 1 Diabetes
  Powers, A., , , , , , , , , , , , , , , , , > ;Journal of the Endocrine Society. 2021 Dec 1
• 307.5: Modified Approach Allowed for Improved Islet Allotransplantation Into Pre-vascularized Sernova Cell PouchTM Device - Preliminary Results of the Phase I/II Clini...
  Piotr J. Bachul, Gabriela S. Generette, Angelica Perez-Gutierrez, Peter Borek, Ling-Jia Wang, Karolina Golab, Lindsay Basto, Laurencia Perea, Martin Tibudan, Braden Ju...> ;Transplantation. 2021 Dec 1
• 9 citations
  Longer-term Benefits and Risks of Sodium-Glucose Cotransporter-2 Inhibitors in Type 2 Diabetes: a Systematic Review and Meta-analysis.
  Jason T. Alexander, Erin M. Staab, Wen Wan, Melissa Franco, Alexandra C. Knitter, M. Reza Skandari, Shari Bolen, Nisa M. Maruthur, Elbert S. Huang, Louis H. Philipson,...> ;Journal of General Internal Medicine. 2021 Nov 30
• 6 citations
  Developmental defects and impaired network excitability in a cerebral organoid model of KCNJ11 p.V59M-related neonatal diabetes
  Gokhan Dalgin, Andrew K. Tryba, Ashley P. Cohen, Soo-Young Park, Louis H. Philipson, Siri Atma W. Greeley, Alfredo J. Garcia> ;Scientific Reports. 2021 Nov 3
• 4 citations
  Insight on Diagnosis and Treatment From Over a Decade of Research Through the University of Chicago Monogenic Diabetes Registry.
  Tiana L Bowden, Lisa R Letourneau-Freiberg, Balamurugan Kandasamy, May Sanyoura, Persephone Tian, Anastasia G Harris, Graeme I Bell, Louis H Philipson, Rochelle N Nayl...> ;Frontiers in Clinical Diabetes and Healthcare. 2021 Nov 1
• 13 citations
  The Longer-Term Benefits and Harms of Glucagon-Like Peptide-1 Receptor Agonists: a Systematic Review and Meta-Analysis
  Jason T. Alexander, Erin M. Staab, Wen Wan, Melissa Franco, Alexandra C. Knitter, M. Reza Skandari, Shari Bolen, Nisa M. Maruthur, Elbert S. Huang, Louis H. Philipson,...> ;Journal of General Internal Medicine. 2021 Sep 10
• 5 citations
  Diabetes With Multiple Autoimmune and Inflammatory Conditions Linked to an Activating SKAP2 Mutation.
  Niklas Rutsch, Chester E. Chamberlain, Wesley Dixon, Lauren Spector, Lisa R. Letourneau-Freiberg, Wint Lwin, Louis H. Philipson, Alexander Zarbock, Karline Saintus, Ju...> ;Diabetes Care. 2021 Jun 25
• 14 citations
  Transparent, Compliant 3D Mesostructures for Precise Evaluation of Mechanical Characteristics of Organoids.
  Hanjun Ryu, Yoonseok Park, Haiwen Luan, Gokhan Dalgin, Kira Jeffris, Hong-Joon Yoon, Ted S. Chung, Jong Uk Kim, Sung Soo Kwak, Geumbee Lee, Hyoyoung Jeong, Jihye Kim, ...> ;Advanced Materials. 2021 May 13
• 7 citations
  Post-Hoc Analysis of a Randomized, Double Blind, Prospective Study at the University of Chicago: Additional Standardizations of Trial Protocol are Needed to Evaluate t...
  , , , , , , , , , , , , , , , , , , , , > ;Cell Transplantation. 2021 Apr 28
• 24 citations
  The demise of islet allotransplantation in the United States: A call for an urgent regulatory update.
  Piotr Witkowski, Louis H. Philipson, Dixon B. Kaufman, Lloyd E. Ratner, Marwan S Abouljoud, Melena D. Bellin, John B. Buse, Fouad Kandeel, Peter G. Stock, David C. Mul...> ;American Journal of Transplantation. 2021 Apr 1
• 3 citations
  Islets Transplantation at a Crossroads - Need for Urgent Regulatory Update in the United States: Perspective Presented During the Scientific Sessions 2021 at the Ameri...
  Witkowski, P., Philipson, L., Buse, J., Robertson, R., Alejandro, R., Bellin, M., Kandeel, F., Baidal, D., Gaglia, J., Posselt, A., Anteby, R., Bachul, P., Al-Salmay, ...> ;Frontiers in Endocrinology. 2021 Jan 1
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Journal Articles

• Effect of Continuous Glucose Monitoring on Hypoglycemia in Older Adults with Type 1 Diabetes  
  Anuj Bhargava, Robin Goland, Irl B Hirsch, Yogish C Kudva, Janet B Mcgill, Louis Philipson, Francesco Vendrame, Ruth S Weinstock, JAMA
• Characterization of Mice Expressing Ins1 Gene Promoter Driven CreERT Recombinase for Conditional Gene Deletion in Pancreatic Beta-cells  
  Tamarina NA, Roe MW, Philipson L, Islets, 1/1/2014
• Distribution of Directional Change as a Signature of Complex Dynamics  
  Burov, S., Tabei, Ali S.M., Huynh, T., Murrell, M., Philipson, L.H., Rice, S.A., Gardel, M.L., Scherer, N.F., Dinner, A.R., Proc Natl Acad Sci U S A., 1/3/2013
• Human Insulin Gene Mutant C43G Is Retained in the ER but Does Not Impair Glucose Homeostasis in Zebrafish  
  Eames, SC, Kinkel, MD, Rajan, S., Prince, VE, Philipson LH, J Diabetes Invest, 1/1/2013
• Metastatic Insulinoma Following Resection of Non-secreting Pancreatic Islet Cell Tumor,  
  Koshy, A., Gordon, I.O., Van Ha, T.G., Kaplan, E.L., Philipson, L.H., Journal of Investigative Medicine High Impact Case Reports, 1/1/2013
• Genetics and Pathophysiology of Neonatal Diabetes Mellitus H  
  Naylor, RN, Greeley, SAW, Bell, GI, Philipson, LH, Journal of Diabetes Investigation, 1/1/2011
• In Vitro Processing and Secretion of Mutant Insulin Proteins That Cause Permanent Neonatal Diabetes  
  Rajan, S, Eames, SC, Park, SY, Labno, C, Bell, GI, Prince, VE, Philipson, LH., Am. J. Physiol. Endo Metab., 1/1/2010
• Neonatal Diabetes Mellitus: A Model for Personalized Medicine  
  Greeley, S.A.W., Tucker, S.E., Naylor, R.N., Bell, G.I., and Philipson, L.H., Trends in Endocrinology and Metabolism, 1/1/2010
• A Model of Action Potentials and Fast Ca2+ Dynamics in Pancreatic Beta-cells  
  Fridlyand, LE, Jacobson, D., and Philipson, L.H., Biophys J., 1/1/2009
• A Brief Perspective on Insulin Production  
  Steiner DF, Park SY, Stoy J, Philipson LH, Bell GI., Diabetes Obes Metab., 1/1/2009
• Reversible Translocation of EYFP-tagged STIM1 Is Coupled to Calcium Influx in Insulin Secreting Beta-cells  
  Tamarina NA, Kuznetsov A, Philipson LH., Cell Calcium., 1/1/2008
• Insulin Mutation Screening in 1044 Patients with Diabetes: Mutations in the INS gene are a Common Cause of Neonatal Diabetes but a Rare Cause of Diabetes Diagnosed in ...  
  Edghill EL, Flanagan SE, Patch AM, Boustred C, Parrish A, Shields B, Shepherd MH, Hussain K, Kapoor RR, Malecki M, Macdonald MJ, Stoy J, Steiner DF, Philipson LH, Bell..., Diabetes, 1/1/2008
• Glucose Homeostasis, Insulin Secretion, and Islet Phospholipids in Mice that Overexpress iPLA2Beta in Pancreatic Beta-Cells and in iPLA2Beta-Null Mice  
  Bao, S., Jacobson, D.A., Wohltmann, M., Bohrer, A., Jin, W., Philipson, L.H. and Turk, J., Am. J. Physiol, 1/1/2008
• Diagnosis and Treatment of Neonatal Diabetes: An United States Experience  
  Stoy J, Greeley SA, Paz VP, Ye H, Pastore AN, Skowron KB, Lipton RB, Cogen FR, Bell GI, Philipson LH; United States Neonatal Diabetes Working Group, Pediatr Diabetes., 1/1/2008
• Single Particle Image Reconstruction of the Human Recombinant Kv21 Channel  
  Adair B, Nunn R, Lewis S, Dukes I, Philipson L, Yeager M., Biophys J., 1/1/2008
• A Protective Role for Nitric Oxide during the Endoplasmic Reticulum Stress Response in Pancreatic Beta-cells  
  Kitiphongspattana K, Khan TA, Ishii-Schrade K, Roe MW, Philipson LH, Gaskins HR, Am J Physiol Endocrinol Metab., 1/1/2007
• Modulation of the Pancreatic Islet betaCell-delayed Rectifier Potassium Channel Kv21 by the Polyunsaturated Fatty Acid Arachidonate  
  Jacobson DA, Weber CR, Bao S, Turk J, Philipson LH., J Biol Chem, 1/1/2007
• Kv21 Ablation Alters Glucose Induced Islet Electrical Activity, Enhancing Insulin Secretion  
  Jacobson DA, Kuznetsov A, Lopez JP, Kash S, ammala CE, Philipson LH., Cell Metabolism, 1/1/2007
• Insulin Gene Mutations as a Cause of Permanent Neonatal Diabetes  
  Stoy, J., Edghill, E.L., Flanagan S.E., Ye, H., Paz V.P., Pluzhnikov, A., Below, J.E. Hayes, M.G. Cox, N.J. Lipkind, G.M., Lipton, R.B., Greeley, S.A., Patch, A.-M. El..., Proc Nat Acad USA, 1/1/2007
• Regulation of cAMP Dynamics by Ca2+ and G-protein Coupled Receptors in the Pancreatic Beta-cell: A Computational Approach  
  Fridlyand LE, Harbeck MC, Roe MW, Philipson LH, Am J Physiol Cell Physiol., 1/1/2007
• Reactive Species, Cellular Repair and Risk Factors in the Onset of Type 2 Diabetes Mellitus: Review and Hypothesis  
  Fridlyand, L.E. and Philipson, L.H., Current Diabetes Reviews, 1/1/2006
• Reversal of Diabetes in NOD Mice without Spleen-cell Derived Beta-cell Regeneration  
  Chong, A.S., Shen, J., Tao, J., Yin, D., Kuznetsov, A., Hara, M., and Philipson, L.H., Science, 1/1/2006
• Oxidative Reactive Species in Cell Injury: Mechanisms In Diabetes Mellitus and Therapeutic Approaches  
  Fridlyand, L.E., Philipson, L.H., Ann N.Y. Acad Sci., 1/1/2006
• Reactive Species and Early Manifestation of Insulin Resistance In Type 2 Diabetes  
  Fridlyand, L.E., Philipson L.H., Diabetes Obes Metab., 1/1/2006
• Improved Outcomes in Islet Isolation and Transplantation by the Use of a Novel Hemoglobin-based O2 Carrier  
  Avila, J., Wong, Y., Barbaro, B., Gangemi, A., Qi, M., Knechle, J., Doubleday, N., Doubleday, M., Churchill, T., Salehi, P., Philipson, L., Shapiro, J., Benedetti, E.,..., Am J Transplant., 1/1/2006
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Books/Book Chapters

• Endocrine Essentials, Endocrine Update for General Medicine 
  Chapter: Monogenic Diabetes: Who Needs MODY Screening? 
  Page 62 - 70Philipson, LH, Naylor, R., Greeley SA, Bell, GI.Editors: Anawalt, BD.The Endocrine Society2012
• Genetic Diagnosis of Endocrine Disorders 
  Chapter: Genetic Testing in Diabetes Mellitus: A Clinical Guide to Monogenic Diabetes 
  Philipson LH, Murphy R, Ellard S, Hattersley AT, Stoy J, Greeley SA, Bell GI, Polonsky KSEditors: Weiss RE, Refetoff S.London, Elsevier2010
• "TRP Channels in Health and Disease” in the Series "Handbook of Experimental Pharmacology 
  Chapter: TRP Channels of the Pancreatic Beta Cell 
  Jacobson, D.A. and Philipson, L.H.Springer-Verlag, Berlin2007
• Commentaries on Perspectives in Diabetes 
  Chapter: Commentary: K+ channels: Generating Excitement in Pancreatic b-Cells. 
  Page 279 - 290Philipson, L.H. and Dukes, I.D.Editors: Robertson, R.P..American Diabetes Association2006
• Landmark Papers in Insulin Biosynthesis 
  Chapter: Foreword 
  A. Lernmark, O. Madsen, and L. H. PhilipsonEditors: Steiner, D.F..Current Medicine Group, London2005
• Diabetes Mellitus: A Fundamental and Clinical Text 
  Chapter: Electrophysiology of the Pancreatic B-cell 
  Houamed, K., Fu, J., Roe, M.W., and Philipson L.H.Editors: LeRoith, D., Taylor, S.I., and Olefsky, J.O..Lippincott, Williams and WilkinsEdition 3,2004
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Lectures

• Can We Prevent Type 1 Diabetes 
  Cairo, Egypt - 1/1/2015
• Insulin Gene Mutations 
  Jerusalem, Israel - 1/1/2015
• Monogenic Genes in Type 2 Diabetes 
  Vancouver, Canada - 1/1/2015
• Monogenic Diabetes and Personalized Genetic Medicine 
  University of Pennsylvania Medicine, Philadelphia, PA - 1/1/2015
• The Clinical & Genetic Spectrum of Monogenic Diabetes 
  Chicago, IL - 1/1/2014
• Subtypes of Type 2 Diabetes in Adults 
  San Francisco, CA - 1/1/2014
• Monogenic Diabetes (Lessons from the University of Chicago) 
  Bangalore, India - 1/1/2014
• Starting Insulin 
  Bangalore, India - 1/1/2014
• Overcoming Barriers to Insulin Use 
  Bangalore, India - 1/1/2014
• Monogenic Diabetes and Beta Cell Dynamics 
  Montreal Diabetes Research Center, Montreal, Canada - 1/1/2014
• Type 1 Diabetes 
  Chicago IL - 1/1/2014
• Update in Diabetes Research and Technology: The Onramp to the Diabetes Digital Highway 
  1/1/2014
• State of Diabetes 
  Springfield, Illinois - 1/1/2014
• Monogenic Diabetes and the Beta Cell 
  Naomi Berrie Diabetes Center, Columbia University, NY, NY - 1/1/2014
• An Imaging-modeling Approach to Insulin Granule Dynamics 
  Kyoto International Conference Center, Kyoto, Japa - 1/1/2013
• Monogenic Diabetes: Lessons from the Chicago Registry 
  Section of Endocrinology, University of Chile, Santiago, Chile - 1/1/2013
• Insulin Mutations and Granule Dynamics 
  New Haven, CN - 1/1/2013
• Mental Health Issues In Diabetes: The Chicago Model 
  Philadelphia, PA - 1/1/2013
• Diabetes 101 
  Chicago, IL - 1/1/2013
• Update in Monogenic Diabetes 
  University of Chicago Kovler Diabetes Center - 1/1/2013
• Monogenic Diabetes (Lessons Learned) 
  Bangalore, India - 1/1/2012
• Incretins in Metabolism 
  Bangalore, India - 1/1/2012
• Cellular Aspects of GPCRs in the Beta Cell 
  Bangalore, India - 1/1/2012
• Case studies in Monogenic Diabetes 
  Bangalore, India - 1/1/2012
• Case Studies in Hypoglycemia 
  Bangalore, India - 1/1/2012
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Other

• Interview on “Good Morning Ireland” 
  RTE 1 (Raidio Teilifis Eireann)
  http://www.rte.ie/player/us/show/10243456/#pos=1162
  1/17/2012
• Monogenic Diabetes 
  WGN/CLTV
  http://www.cltv.com/wgntvmonogenic-diabetes-20120203,0,1917756.story
  Chicago, IL - 1/1/2012
• Diabetes Awareness 
  NBC Chicago Non-Stop Channel “Weekends with Whitney”
  1/1/2011
• Diabetes and the Student Athlete 
  WCIU-TV 26.1 Chicago, Kenny McWilliams show
  1/1/2011
• Funding for Diabetes Research 
  Philipson, LH, Reedy, P. Flom, J., Chicago Tribune
  1/26/2010
• Baseball and Growth Hormones: Big Muscles, Big Bodies, Big Trouble. Letter 
  Landau, R. and Philipson, L.H., The Wall Street Journal
  1/20/2007
• Visualizing Calcium Signaling in Cells by Digitized Conventional Wide-field and Confocal Fluorescence Microscopy 
  Roe, M.W., Fiekers, J.F., Philipson, L.H., and Bindokas, V.P., Humana Press Handbook
  1/1/2005
• Insulin Biosynthesis, Secretion, Structure, And Structure-Activity Relationships 
  Pittman, I., Philipson, L.H., Steiner, D.F., “Endocrinology”
  http://www.endotext.org/index.htm
  1/1/2004
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