LynnMarieAbellMD

PubMed

• Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors.
  Hu, C. H.,Wang, T. C.,Qiao, J. X.,Haque, L.,Chen, AYA.,Taylor, D. S.,Ying, X.,Onorato, J. M.,Galella, M.,Shen, H.,Huang, C. S.,Toussaint, N.,Li, Y. X.,Abell, L.,Adam, ...> ;Bioorg. Med. Chem. Lett.. 2018 Oct 24
• Triazolopyrimidines identified as reversible myeloperoxidase inhibitors.
  Duclos, F.,Abell, L. M.,Harden, D. G.,Pike, K.,Nowak, K.,Locke, G. A.,Duke, G. J.,Liu, X.,Fernando, G.,Shaw, S. A.,Vokits, B. P.,Wurtz, N. R.,Viet, A.,Valente, M. N.,S...> ;Medchemcomm. 2018 Aug 16
• Development of a rapidfire mass spectrometry assay and a fluorescence assay for kynurenine aminotransferase II.
  Lu, H.,Kopcho, L.,Ghosh, K.,Witmer, M.,Parker, M.,Gupta, S.,Paul, M.,Krishnamurthy, P.,Laksmaiah, B.,Xie, D.,Tredup, J.,Zhang, L.,Abell, L. M.> ;Anal. Biochem.. 2016 Feb 14
• Conformationally Constrained ortho-Anilino Diaryl Ureas: Discovery of 1-(2-(1'-Neopentylspiro[indoline-3,4'-piperidine]-1-yl)phenyl)-3-(4-(trifluoromethoxy)phenyl)urea...
  Qiao, J. X.,Wang, T. C.,Ruel, R.,Thibeault, C.,L'heureux, A.,Schumacher, W. A.,Spronk, S. A.,Hiebert, S.,Bouthillier, G.,Lloyd, J.,Pi, Z.,Schnur, D. M.,Abell, L. M.,Hu...> ;J. Med. Chem.. 2013 Oct 30
• Nonclinical Toxicology Assessments Support the Chronic Safety of Dapagliflozin, a First-in-Class Sodium-Glucose Cotransporter 2 Inhibitor.
  Tirmenstein, M.,Dorr, T. E.,Janovitz, E. B.,Hagan, D.,Abell, L. M.,Onorato, J. M.,Whaley, J. M.,Graziano, M. J.,Reilly, T. P.> ;Int. J. Toxicol.. 2013 Oct 08
• Dissecting the Activation of Thienopyridines by Cytochrome P450's Using a Pharmacodynamic Assay in Vitro.
  Abell, L.M., Liu, E.C.> ;J Pharmacol Exp Ther. 2011 Nov
• Understanding Intra-Abdominal Hypertension: From the Bench to the Bedside.
  Mufarrej, F.A., Abell, L.M., Chawla, L.S.> ;J Intensive Care Med. 2011-04-27
• Anion gap, anion gap corrected for albumin, and base deficit fail to accurately diagnose clinically significant hyperlactatemia in critically ill patients.
  Chawla, L.S., Jagasia, D., Abell, L.M., Seneff, M.G., Egan, M., Danino, N., Nguyen, A., Ally, M., Kimmel, P.L., Junker, C.> ;J Intensive Care Med. 2008-03-01
• Development and validation of a platelet calcium flux assay using a fluorescent imaging plate reader.
  Liu, E.C., Abell, L.M.> ;Anal Biochem. 2006 Oct 15
• Use of the kinetic equilibrium between aminoacyl-tRNA formation and hydrolysis in inhibition assays of aminoacyl-tRNA synthetase.
  Jordan, D. B., Abell, L. M., Picollelli, M. A., Senator, D. R., Mason, J. L., Rogers, M. J., Rendina, A. R.> ;Anal Biochem. 2001 Nov 1
• Identifying critically ill patients at high risk for developing acute renal failure: a pilot study.
  Chawla, L. S., Abell, L., Mazhari, R., Egan, M., Kadambi, N., Burke, H. B., Junker, C., Seneff, M. G., Kimmel, P. L.> ;Kidney Int. 2005 Nov
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