LynneV.AbruzzoMD

PubMed

• 4 citations
  Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia.
  Qu Jiang, Johanna Stachelscheid, Johannes Bloehdorn, Alicja Pacholewska, Christoph Aszyk, Francien Grotenhuijs, Tony Müller, Ozlem Onder, Prerana Wagle, Carmen D Herli...> ;Blood. 2023 Jul 6
• Refining prognosis in chronic lymphocytic leukemia with normal Fluorescence in situ hybridization results.
  Matthew R Avenarius, Ying Huang, Jonathan Hyak, John C Byrd, Seema A Bhat, Michael Grever, Adam S Kittai, Kerry A Rogers, Dan Jones, Weiqiang Zhao, Nyla A Heerema, Lyn...> ;Hematological Oncology. 2023 Oct 1
• 5 citations
  Electronic Health Records and Genomics: Perspectives from the Association for Molecular Pathology Electronic Health Record (EHR) Interoperability for Clinical Genomics...
  Alexis B. Carter, Lynne V. Abruzzo, Julie Woolworth Hirschhorn, Dan Jones, Danielle C. Jordan, Mehdi Nassiri, Shuji Ogino, Nimesh R. Patel, Christopher G. Suciu, Robyn...> ;The Journal of Molecular Diagnostics. 2021 Oct 15
• 1 citations
  RCytoGPS: An R Package for Reading and Visualizing Cytogenetics Data.
  Zachary B. Abrams, Dwayne G. Tally, Lynne V. Abruzzo, Kevin R. Coombes> ;Bioinformatics. 2021 Oct 2
• Correction: Genomic analysis of cellular hierarchy in acute myeloid leukemia using ultrasensitive LC-FACSeq
  Caner Saygin, Eileen Hu, Pu Zhang, Steven Sher, Arletta Lozanski, Tzyy-Jye Doong, Deedra Nicolet, Shelley Orwick, Jadwiga Labanowska, Jordan N. Skinner, Casey Cempre, ...> ;Leukemia. 2021 Sep 3
• 23 citations
  The impact of increasing karyotypic complexity and evolution on survival in CLL patients treated with ibrutinib.
  Adam Kittai, Cecelia R. Miller, Daniel Goldstein, Ying Huang, Lynne V. Abruzzo, Kyle A. Beckwith, Seema A. Bhat, David A. Bond, Michael R. Grever, Nyla A. Heerema, Ker...> ;Blood. 2021 Jul 27
• 3 citations
  Genomic analysis of cellular hierarchy in acute myeloid leukemia using ultrasensitive LC-FACSeq.
  Caner Saygin, Eileen Hu, Pu Zhang, Steven Sher, Arletta Lozanski, Tzyy-Jye Doong, Deedra Nicolet, Shelley Orwick, Jadwiga Labanowska, Jordan N. Skinner, Casey Cempre, ...> ;Leukemia. 2021 May 21
• 1 citations
  Significance of chromosome 2p gain in ibrutinib-treated chronic lymphocytic leukemia patients.
  Cecelia R. Miller, Ying Huang, Amy S. Ruppert, Jadwiga Labanowska, Samantha Jaglowski, Kami J. Maddocks, Kerry A. Rogers, Seema A. Bhat, Adam Kittai, Michael R. Grever...> ;Leukemia. 2021 Apr 5
• 1 citations
  Pattern recognition in lymphoid malignancies using CytoGPS and Mercator.
  Zachary B. Abrams, Dwayne G. Tally, Lin Zhang, Caitlin E. Coombes, Philip R. O. Payne, Lynne V. Abruzzo, Kevin R. Coombes> ;BMC Bioinformatics. 2021 Mar 1
• 26 citations
  Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.
  Janek S. Walker, Zachary A. Hing, Bonnie K. Harrington, Jordan M. Baumhardt, Hatice Gulcin Ozer, Amy Lehman, Brian Giacopelli, Larry Beaver, Katie Williams, Jordan N. ...> ;Journal of Hematology & Oncology. 2021 Jan 15
• 1 citations
  CytoGPS: A large-scale karyotype analysis of CML data.
  Zachary B. Abrams, Suli Li, Lin Zhang, Caitlin E. Coombes, Philip R. O. Payne, Nyla A. Heerema, Lynne V. Abruzzo, Kevin R. Coombes> ;Cancer Genetics. 2020 Oct 2
• 52 citations
  Phase II Study of Combination Obinutuzumab, Ibrutinib, and Venetoclax in Treatment-Naïve and Relapsed or Refractory Chronic Lymphocytic Leukemia.
  Kerry A. Rogers, Ying Huang, Amy S. Ruppert, Lynne V. Abruzzo, Barbara L. Andersen, Farrukh T. Awan, Seema A. Bhat, Allison Dean, Margaret S. Lucas, Christin Banks, Ca...> ;Journal of Clinical Oncology. 2020 Aug 14
• 10 citations
  Unsupervised machine learning and prognostic factors of survival in chronic lymphocytic leukemia
  Caitlin E. Coombes, Zachary B. Abrams, Suli Li, Lynne V. Abruzzo, Kevin R. Coombes> ;Journal of the American Medical Informatics Association. 2020 Jul 1
• 8 citations
  The clinical impact of time to response in de novo accelerated-phase chronic myeloid leukemia
  Maro Ohanian, Hagop M. Kantarjian, Mahran Shoukier, Sara Dellasala, Arine Musaelyan, Graciela M. Nogueras González, Elias Jabbour, Lynne V. Abruzzo, Srdan Verstovsek, ...> ;American Journal of Hematology. 2020 Jun 17
• 14 citations
  Time-to-progression after front-line fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy for chronic lymphocytic leukaemia: a retrospective, multicohort st...
  Carmen D. Herling, Kevin R. Coombes, Axel Benner, Johannes Bloehdorn, Lynn L. Barron, Zachary B. Abrams, Tadeusz Majewski, Jolanta Bondaruk, Jasmin Bahlo, Kirsten Fisc...> ;The Lancet. Oncology. 2019 Sep 30
• Inferring clonal heterogeneity in cancer using SNP arrays and whole genome sequencing.
  Mark R Zucker, Lynne V Abruzzo, Carmen D Herling, Lynn L Barron, Michael J Keating, Zachary B Abrams, Nyla Heerema, Kevin R Coombes> ;Bioinformatics. 2019 Sep 1
• 23 citations
  Developmental subtypes assessed by DNA methylation-iPLEX forecast the natural history of chronic lymphocytic leukemia.
  Brian Giacopelli, Qiuhong Zhao, Amy S. Ruppert, Akwasi Agyeman, Christoph Weigel, Yue Zhong Wu, Madelyn M. Gerber, Kari G. Rabe, Melissa C. Larson, Junyan Lu, James S....> ;Blood. 2019 Aug 22
• 6 citations
  CytoGPS: a web-enabled karyotype analysis tool for cytogenetics.
  Zachary B. Abrams, Lin Zhang, Lynne V. Abruzzo, Nyla A. Heerema, Suli Li, Tom Dillon, Ricky Rodriguez, Kevin R. Coombes, Philip R. O. Payne> ;Bioinformatics. 2019 Dec 15
• Intricacies of CLL cytogenetic complexity
  Lynne V. Abruzzo> ;Blood. 2019 Mar 14
• Orbital extramedullary leukaemia is not a rare entity - response to Paydas.
  Maro Ohanian, Cynthia Tung, Lynne V. Abruzzo> ;British Journal of Haematology. 2019 Mar 14
• 1 citations
  Inferring clonal heterogeneity in cancer using SNP arrays and whole genome sequencing.
  Mark R Zucker, Lynne V Abruzzo, Carmen D Herling, Lynn L Barron, Michael J Keating, Zachary B Abrams, Nyla Heerema, Kevin R Coombes> ;Bioinformatics. 2019 Sep 1
• 47 citations
  MYC protein expression is an important prognostic factor in acute myeloid leukemia
  Maro Ohanian, Uri Rozovski, Rashmi Kanagal-Shamanna, Lynne V. Abruzzo, Sanam Loghavi, Tapan M. Kadia, Andrew Futreal, Kapil N. Bhalla, Zhuang Zuo, Yang O. Huh, Sean M....> ;Leukemia & Lymphoma. 2019 Jan 2
• 17 citations
  Trisomy 12 chronic lymphocytic leukemia expresses a unique set of activated and targetable pathways.
  Lynne V. Abruzzo, Carmen D. Herling, George A. Calin, Christopher C. Oakes, Lynn L. Barron, Haley E. Banks, Vikram Katju, Michael J. Keating, Kevin R. Coombes> ;Haematologica. 2018 Dec 1
• Correction: Acute myeloid leukemia with t(4;12)(q12;p13): an aggressive disease with frequent involvement of PDGFRA and ETV6.
  Jingyi Li, Jie Xu, Lynne V Abruzzo, Guilin Tang, Shaoying Li, M James You, Gary Lu, Elias J Jabbour, Qi Deng, Carlos E Bueso-Ramos, L Jeffrey Medeiros, C Cameron Yin> ;Oncotarget. 2018 Sep 28
• 6 citations
  Thirty biologically interpretable clusters of transcription factors distinguish cancer type
  Zachary B. Abrams, Mark Zucker, Min Wang, Amir Asiaee Taheri, Lynne V. Abruzzo, Kevin R. Coombes> ;BMC Genomics. 2018 Oct 11
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Journal Articles

• Trisomy 12 Chronic Lymphocytic Leukemia Expresses a Unique Set of Activated and Targetable Pathways  
  Michael J Keating, Lynne V Abruzzo, Haematologica

Lectures

• Mutations in the Ras Pathway in Pre-Treatment Chronic Lymphocytic Leukemia Are Associated with VH1-69: Linking B-Cell Receptor Stereotypy to Downstream Signaling Events 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018