MarionECouchMD

PubMed

• 9 citations
  Profiling of Adipose and Skeletal Muscle in Human Pancreatic Cancer Cachexia Reveals Distinct Gene Profiles with Convergent Pathways.
  Ashok Narasimhan, Xiaoling Zhong, Ernie P. Au, Eugene P. Ceppa, Atilla Nakeeb, Michael G. House, Nicholas J. Zyromski, C. Max Schmidt, Katheryn N. H. Schloss, Daniel E...> ;Cancers. 2021 Apr 20
• 9 citations
  Metabolic Biomarkers for the Early Detection of Cancer Cachexia.
  Thomas M. O’Connell, Lilian Golzarri-Arroyo, Fabrizio Pin, Rafael Barreto, Stephanie L. Dickinson, Marion E. Couch, Andrea Bonetto> ;Frontiers in Cell and Developmental Biology. 2021 Jan 1
• 41 citations
  The systemic activin response to pancreatic cancer: implications for effective cancer cachexia therapy.
  Xiaoling Zhong, Marianne Pons, Christophe Poirier, Yanlin Jiang, Jianguo Liu, George E. Sandusky, Safi Shahda, Attila Nakeeb, C. Max Schmidt, Michael G. House, Eugene ...> ;Journal of Cachexia, Sarcopenia and Muscle. 2019 Jul 8
• 9 citations
  Treatment with Soluble Activin Receptor Type IIB Alters Metabolic Response in Chemotherapy-Induced Cachexia
  Thomas M. O’Connell, Fabrizio Pin, Marion E. Couch, Andrea Bonetto> ;Cancers. 2019 Aug 21
• 37 citations
  PDK4 drives metabolic alterations and muscle atrophy in cancer cachexia.
  Fabrizio Pin, Leah J. Novinger, Joshua R. Huot, Robert A. Harris, Marion E. Couch, Thomas M. O’Connell, Andrea Bonetto> ;FASEB Journal. 2019 Mar 20
• 127 citations
  Cachexia induced by cancer and chemotherapy yield distinct perturbations to energy metabolism
  Fabrizio Pin, Rafael Barreto, Marion E. Couch, Andrea Bonetto, Thomas M. O’Connell> ;Journal of Cachexia, Sarcopenia and Muscle. 2019 Jan 24
• 91 citations
  Preservation of muscle mass as a strategy to reduce the toxic effects of cancer chemotherapy on body composition
  Fabrizio Pin, Marion E. Couch, Andrea Bonetto> ;Current Opinion in Supportive and Palliative Care. 2018 Dec 1
• 1 citations
  Oropharyngeal histoplasmosis in an HIV-negative patient.
  Mohamedkazim Alwani, Todd J. Wannemuehler, Don-John Summerlin, Marion E. Couch> ;Ear, Nose, & Throat Journal. 2018 Oct 1
• 64 citations
  Growth of ovarian cancer xenografts causes loss of muscle and bone mass: a new model for the study of cancer cachexia.
  Fabrizio Pin, Rafael Barreto, Yukiko Kitase, Sumegha Mitra, Carlie E. Erne, Leah J. Novinger, Teresa A. Zimmers, Marion E. Couch, Lynda F. Bonewald, Andrea Bonetto> ;Journal of Cachexia, Sarcopenia and Muscle. 2018 Jul 15
• 84 citations
  Three cachexia phenotypes and the impact of fat-only loss on survival in FOLFIRINOX therapy for pancreatic cancer.
  Joshua K. Kays, Safi Shahda, Melissa Stanley, Teresa M. Bell, Bert H. O'Neill, Marc D. Kohli, Marion E. Couch, Leonidas G. Koniaris, Teresa A. Zimmers> ;Journal of Cachexia, Sarcopenia and Muscle. 2018 Jul 5
• 93 citations
  Chemotherapy-induced muscle wasting: association with NF-κB and cancer cachexia.
  Jeffrey S. Damrauer, Michael E. Stadler, Swarnali Acharyya, Albert S. Baldwin, Marion E. Couch, Denis C. Guttridge> ;European Journal of Translational Myology. 2018 Jun 6
• 36 citations
  ACVR2B/Fc counteracts chemotherapy-induced loss of muscle and bone mass
  Rafael Barreto, Yukiko Kitase, Tsutomu Matsumoto, Fabrizio Pin, Kyra C. Colston, Katherine E. Couch, Thomas M. O’Connell, Marion E. Couch, Lynda F. Bonewald, Andrea Bo...> ;Scientific Reports. 2017 Oct 31
• 84 citations
  Gender differences in academic surgery, work-life balance, and satisfaction.
  Dadrie Baptiste, Alison M. Fecher, Scott C. Dolejs, Joseph Yoder, C. Maximillian Schmidt, Marion E. Couch, Duy Khanh P. Ceppa> ;The Journal of Surgical Research. 2017 Oct 1
• 6 citations
  Erratum to: Exogenous GDF11 induces cardiac and skeletal muscle dysfunction and wasting.
  Teresa A. Zimmers, Yanlin Jiang, Meijing Wang, Tiffany W. Liang, Joseph E. Rupert, Ernie D. Au, Francesco E. Marino, Marion E. Couch, Leonidas G. Koniaris> ;Basic Research in Cardiology. 2017 Sep 1
• 72 citations
  Exogenous GDF11 induces cardiac and skeletal muscle dysfunction and wasting
  Teresa A. Zimmers, Yanling Jiang, Meijing Wang, Tiffany W. Liang, Joseph E. Rupert, Ernie D. Au, Francesco E. Marino, Marion E. Couch, Leonidas G. Koniaris> ;Basic Research in Cardiology. 2017 Jun 24
• 45 citations
  Differential Bone Loss in Mouse Models of Colon Cancer Cachexia.
  Andrea Bonetto, Joshua K. Kays, Valorie A. Parker, Ryan R. Matthews, Rafael Barreto, Melissa J. Puppa, Kyung Shin Kang, James A. Carson, Theresa A. Guise, Khalid S. Mo...> ;Frontiers in Physiology. 2017 Jan 11
• 4 citations
  Post-translationally modified muscle-specific ubiquitin ligases as circulating biomarkers in experimental cancer cachexia.
  Roberto Mota, Jessica E. Rodríguez, Andrea Bonetto, Thomas M. O’Connell, Scott A. Asher, Traci L. Parry, Pamela Lockyer, Christopher R. McCudden, Marion E. Couch, Mont...> ;American Journal of Cancer Research. 2017 Jan 1
• 31 citations
  Skeletal muscle fiber size and fiber type distribution in human cancer: Effects of weight loss and relationship to physical function
  Michael J. Toth, Damien M. Callahan, Mark S. Miller, Timothy W. Tourville, Sarah B. Hackett, Marion E. Couch, Kim Dittus> ;Clinical Nutrition. 2016 Dec 1
• 14 citations
  Blunt cerebrovascular injury following craniomaxillofacial fractures: A systematic review
  Gregory Kelts, Stephen Maturo, Marion E. Couch, Cecelia E. Schmalbach> ;The Laryngoscope. 2017 Jan 1
• 8 citations
  Grant-Writing Pearls and Pitfalls: Maximizing Funding Opportunities
  Jeffrey C. Liu, Melissa A. Pynnonen, Maie A. St. John, Eben L. Rosenthal, Marion E. Couch, Cecelia E. Schmalbach> ;Otolaryngology--Head and Neck Surgery. 2016 Feb 1
• 16 citations
  Perception of Shame in Otolaryngology-Head and Neck Surgery Training
  Kevin C. McMains, Jennifer L. Peel, Erik K. Weitzel, Hirak Der-Torossian, Marion E. Couch> ;Otolaryngology--Head and Neck Surgery. 2015 Aug 4
• 24 citations
  Cancer cachexia update in head and neck cancer: Pathophysiology and treatment.
  Marion E. Couch, Kim Dittus, Michael J. Toth, Monte S. Willis, Denis C. Guttridge, Jonathan R. George, Eric Y. Chang, Christine G. Gourin, Hirak Der-Torossian> ;Head & Neck. 2015 Jul 1
• 50 citations
  Cancer cachexia update in head and neck cancer: Definitions and diagnostic features
  Marion E. Couch, Kim Dittus, Michael J. Toth, Monte S. Willis, Denis C. Guttridge, Jonathan R. George, Christie A. Barnes, Christine G. Gourin, Hirak Der-Torossian> ;Head & Neck. 2015 Apr 1
• 2 citations
  Social Media Meets Population Health: A Sentiment And Demographic Analysis of Tobacco and E-Cigarette Use Across The "Twittersphere"
  Eric M. Clark, Christopher A. Jones, Diann E. Gaalema, Thomas J. White, Ryan Redner, R. Everett, Peter Sheridan Dodds, Marion E. Couch, Christopher M. Danforth> ;Value in Health. 2014 Nov 1
• 10 citations
  Defining quality in the era of health care reform.
  Christine G. Gourin, Marion E. Couch> ;JAMA Otolaryngology-- Head & Neck Surgery. 2014 Nov 1
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Journal Articles

• The Effect of Weight Loss on Short-term Outcomes and Cost of Care After Head and Neck Cancer Surgery  
  Gourin C, Couch M, Johnson J, Ann Otol Rhinol Laryngol, 1/1/2014
• Skeletal muscle adaptations to cancer and its treatment: their fundamental basis and contribution to functional disability  
  Der-Torossian H, Couch M, Dittus K, Toth M, Crit Rev Eukaryot Gene Expr, 1/1/2013
• Metabolic derangements in the gastrocnemius and the effect of Compound A therapy in a murine model of cancer cachexia  
  Der-Torossian H, Wysong A, Shadfar S, Willis M, McDunn J, Couch M, J Cachexia Sarcopenia Muscle, 1/1/2013
• Mechanisms underlying skeletal muscle contractile dysfunction in human cancer: reduced myofilament protein function and cross-bridge kinetics  
  Toth M, Miller M, Callahan D, Sweeny A, Nunez I, Grunberg S, Der-Torossian H, Couch M, Dittus K, J Appl Physiol, 1/1/2013
• Cancer cachexia’s metabolic signature in a murine model confirms a distinct entity  
  Der-Torossian H, Asher S, Winnike J, Wysong A, Yin X, Willis M, O’Connell T, Couch M, Metabolomics, 1/1/2013
• Translational implications of novel findings in cancer cachexia: the use of metabolomics and the potential of cardiac malfunction  
  Couch M, Gourin C, Der-Torrossian H, Opin Support Palliat Care, 1/1/2012
• Chromobacterium Violaceum necrotizing fasciitis: A case report and review of the literature  
  Seigel J, Stadler M, Lombrano J, Almony J, Couch M, Belhorn T, ENT Journal, 1/1/2012
• Different Cellular p16INK4a Localization may Signal Different Survival Outcomes in Head and Neck Cancer  
  Zhao N, Ang M, Yin Z, Patel M, Fritchie K, Thorne L, Muldrew K, Hayward M, Sun W, Wilkerson M, Chera B, Hackman T, Zanation A, Grilley-Olson J, Couch M, Shockley W, We..., Br J Cancer, 1/1/2012
• Incidence of Nodal Disease After Nonsurgical Therapy in Head and Neck Squamous Cell Carcinoma Patients With Bilateral Neck Disease: Can a Bilateral Neck Dissection be ...  
  Fried D, Weissler M, Shores C, Couch M, Hayes N,Hackman T, Zanation A, Qaqish B, Chera B, Am J Clin Oncol, 1/1/2012
• Selective inhibition of NF-Kappa-B with NBD peptide reduces tumor-induced wasting in a murine model of cancer cachexia in vivo  
  Wysong A, Asher S, Yin X, Gore M, Weinstein L, Guttridge D, Baldwin A, Couch M, Willis M, J Cancer Science Therapy, 1/1/2011
• NF-kappa-B inhibition protects against tumor-induced cardiac atrophy in vivo  
  Wysong A, Couch M, Shadfar S, Li L, Rodriguez J, Asher S, Yin X, Gore M, Baldwin A, Patterson C, Willis M, Am J Pathol, 1/1/2011
• Phase II Trial of Hyperfractionated IMRT and Concurrent Weekly Cisplatin for Stage III and IVA Head and Neck Cancer  
  Maquire P, Couch M, Meyerson M, Nichols M, Hayes DN, Int J Radiat Oncol Biol Phys, 1/1/2011
• Association of p16INK4a overexpression with improved outcomes in young patients with squamous cell cancers of the oral tongue  
  Harris S, Thorne L, Seaman WT, Hayes DN, Couch M, Kimple R, Head Neck, 1/1/2011
• Randomised clinical trial: high-dose acid suppression for chronic cough – a double-blind placebo-controlled study  
  Shaheen N, Crockett D, Bright S, Madanick R, Buckmire R, Couch M, Dellon E, Galanko J, Sharpless G, Morgan D, Spacek M, Heidt-Davis P, Henke D, Aliment Pharmacol Ther, 1/1/2011
• Detection and quantitation of HPV in genital and oral tissues and fluids by real time PCR  
  Seaman WT, Andrews E, Couch M, Kojic EM, Cu-Uvin S, Palefsky J, Deal AM, Webster-Cyriaque J, Virol J, 1/1/2010
• Invited Commentary, Robotic-assisted Surgery  
  Couch M, Zanation A, Arch Surg, 1/1/2010
• Outcomes of a combined antegrade and retrograde approach for dilation of radiation inducted esophageal strictures  
  Dellon E, Cullen N, Madanick R, Buckmire R, Grimm I, Weissler M, Couch M, Shaheen N, Gastrointest Endosc, 1/1/2010
• Chromobacterium violaceum necrotizing fasciitis: a case report and review of the literature  
  Speigel J, Lombrano J, Couch M, Stadler M, Belhorn T, Ear, Nose & Throat J, 1/1/2010
• Never-Smokers, Never-Drinkers: A Unique Clinical Subgroup of Young Patients with Head and Neck Squamous Cell Cancers  
  Harris S, Kimple R, Hayes DN, Couch M, Rosenman J, Head & Neck, 1/1/2010
• Concurrent HPV-associated tonsillar carcinoma in two couples  
  Andrews E, Shores C, Hayes N, Couch M, Southerland J, Morris D, Seaman T, Webster-Cyriaque J, J Infectious Diseases, 1/1/2009
• Chemotherapy-induced muscle wasting: Association with NF-kB and Cancer Cachexia  
  Damrauer J, Stadler M, Acharyya S, Baldwin A, Couch M, Guttridge D, Basic Applied Myology, 1/1/2008
• Metabolomic Analysis of Cancer Cachexia Reveals Distinct Lipid and Glucose Alterations  
  O’Connell T, Ardeshirpour F, Asher S, Winnike J, Yin X, George J, Guttridge D, He W, Wysong A, Willis M, Couch M, Metabolomics, 1/1/2008
• Molecular Biology of Head & Neck Cancer  
  Stadler M, Patel M, Couch M, Hayes DN, Hemat Onc Clin N Am, 1/1/2008
• Iimmunocompetent murine model of cancer cachexia for head and neck squamous cell carcinoma  
  Cannon TY, Shores C, Guttridge D, Lai V, George J, Couch M, Head Neck, 1/1/2008
• Association of Immune Response to Oncoprotein p53 with Specific HLA Class II Haplotypes  
  Couch M, Ferris R, Brennan J, Koch W, Castro R, Erlich H, Jaffee E, Sidransky D, Clin Cancer Research, 1/1/2007
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Books/Book Chapters

• Human Papilloma Virus 
  Chapter: Clinical Presentation of HPV-related Oropharyngeal Carcinoma 
  Moore M, Couch M2014
• Technological Advances in Surgery, Trauma, and Critical Care. 
  Chapter: Advances in Head and Neck Surgery. 
  Stadler M, Patel M, Couch M2014
• KJ Lee’s Essentials of Otolaryngology 
  Chapter: Nutrition 
  Herrington H, Couch M2011
• Sabiston’s Textbook of Surgery 
  Chapter: Head and Neck Cancer 
  Burkey B, Couch M, Lorenz RElsevier, IncEdition 19th,2010
• Otolaryngology -Head and Neck Surgery 
  Chapter: History, Physical Examination, and Preoperative Evaluation. 
  Couch M., Kunar D, Blaugrund JMosby-Year Book, Inc.Edition 5th,2009
• Head and Neck Surgery and Oncology. 
  Chapter: Nutrition for Head and Neck Cancer Patients. 
  Couch M, George JBC Decker2008
• AAO-HNSF National Resident Online Study Guide 
  Chapter: Rhinosinusitis. 
  Couch M, Melroy CAAO-HNSF2006
• AAO-HNSF National Resident Online Study Guide 
  Chapter: Nutrition in Head and Neck Cancer. 
  Couch M, Zanation AAAO-HNSF2006
• Head & Neck Surgery – Otolaryngology 
  Chapter: Tracheotomy and Intubation. 
  Weissler M, Couch MLippincottEdition 4th,2005
• Otolaryngology -Head and Neck Surgery 
  Chapter: Medical Informatics in Otolaryngology. 
  Goldenberg D, Couch MMosby-Year Book, Inc.Edition 4th,2005
• Contemporary Issues in Oral Cancer. 
  Chapter: Gene Therapy for Oral Cancer. 
  Page 343 - 342Couch M, O’Malley BWOxford Press2000
• Advanced Gene Delivery: from Concepts to Pharmaceutical Products. 
  Chapter: Gene Therapy for Cancer: Strategies and Review of Clinical Trials. 
  Page 281 - 310O’Malley BW, Couch MHarwood Academic Publishers, Switzerland1999
• Otolaryngology -Head and Neck Surgery. Volume 1 
  Chapter: Otolaryngology - Head and Neck Surgery History and Physical Examination. 
  Page 3 - 14Couch MMosby-Year Book, Inc.Edition 3rd,1998
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Abstracts/Posters

• Presenter, Research Program
  Couch M, Cancer Cachexia: Molecular Mechanisms and Therapeutic Approaches International Meeting, Boston, MA, 1/1/2012
• Presenter, Research Program
  Couch M, American Head & Neck Society International Meeting, Toronto, Canada, 1/1/2012
• Metabolic Derangements of Cancer Cachexia
  Couch M, 6th International Cachexia Conference, Milan, Italy, 1/1/2011
• Cancer Cachexia’s Metabolic Fingerprint in a Murine Model
  Couch M, 6th International Cachexia Conference, Milan, Italy, 1/1/2011
• Metabolomics of Cancer Cachexia
  Couch M, 4th International Cachexia Conference Abstract, 1/1/2007
• The Effect of Altered TLR4 Signaling on Cancer Cachexia. Poster
  Couch M, AHNS Annual Meeting & Research Workshop on the Biology, Prevention, and Treatment of Head and Neck Cancer, 1/1/2006
• An Animal Model of Human Head and Neck Cancer Cachexia. Poster
  Couch M, 3rd Cachexia Conference, 1/1/2005
• Efficacy of COX-2 Inhibitors on Tumor Anorexia-Cachexia Syndrome in Patients with Cancer of the Head and Neck and Gastrointestinal Tract. Poster
  Couch M, 3rd Cachexia Conference, 1/1/2005
• Management of Castleman’s Disease. Poster
  Couch M, AAO-HNSF, 1/1/2003
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Lectures

• Update on HPV and Head and Neck Cancer, Invited Speaker 
  Vail, CO - 1/2/2015
• Metabolic Derangements in Cancer Cachexia 
  Montreal, Canada - 1/27/2014
• Invited Speaker: Vermont’s Healthcare Reform Experience. 
  Stowe, VT - 1/25/2014
• Invited Panelist: “Grant Writing Pearls & Pitfalls: Maximizing Your Funding.” 
  Orlando, FL - 1/21/2014
• The Importance of Diversity in OHNS 
  Gainesville, FL - 1/20/2014
• Update on HPV in Oropharyngeal Carcinoma 
  Gainesville, FL - 1/20/2014
• Healthcare Reform for Head & Neck Surgeons 
  West Orange, NJ - 1/18/2014
• HPV Oropharyngeal Carcinoma – A New Disease 
  West Orange, NJ - 1/18/2014
• Invited Panelist: Healthcare Delivery/Affordable Care Act – What Do We Know and What Can We Do? 
  Las Vegas, NV - 1/16/2014
• Invited Guest Speaker: Importance of Gender Diversity. 
  Ottawa, Canada - 1/12/2014
• Invited Panelist-Necessary Changes: Professionalism, Peer Support, and Pocketbook. 
  Miami Beach, FL - 1/12/2014
• Invited Speaker: The Importance of Diversity. 
  Miami Beach, FL - 1/10/2014
• Healthcare Reform for Head & Neck Surgeons, Invited Speaker 
  San Francisco, CA - 1/7/2014
• Young Patients with H&N Cancer: Etiology and Prognosis 
  San Francisco, CA - 1/7/2014
• The Importance of Gender Diversity in OHNS 
  Saint Louis University, St. Louis, MO - 1/6/2014
• Update on HPV in Head and Neck Carcinoma 
  Saint Louis University, St. Louis, MO - 1/6/2014
• Invited Speaker: Healthcare Economics. 
  University of Colorado, Vail, CO - 1/3/2014
• Invited Keynote Speaker: Healthcare Reform in the North. 
  Louisville, KY - 1/1/2014
• Head and Neck Cancer, Faculty Lecturer 
  University of North Carolina School of Medicine - 1/1/2014
• Neck Masses, Faculty Lecturer 
  University of North Carolina School of Medicine - 1/1/2014
• Gender Diversity in Otolaryngology – Why it Matters 
  Philadelphia, PA - 1/1/2014
• Update on HPV and Head and Neck Cancer 
  Philadelphia, PA - 1/1/2014
• Invited Panelist: Leadership. 
  Vancouver, Canada - 1/29/2013
• Cancer Cachexia Update for Head and Neck Surgeons 
  University of Texas San Antonio, San Antonio, TX - 1/22/2013
• Business of Medicine 
  University of Texas San Antonio, San Antonio, TX - 1/22/2013
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