MarkWilliamAlbersMDPhD

Neurology • Boston, MA

Assistant Professor, Neurology-Massachusetts General Hospital, Harvard Medical School

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Office
15 Parkman Street
Wacc 830
Boston, MA 02114
Phone+1 617-726-1728

Fax+1 617-726-4101
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Education & Training

Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Neurology, 1997 - 2000
Massachusetts General HospitalResidency, Internal Medicine, 1995 - 1997
Harvard Medical SchoolClass of 1995

Certifications & Licensure

MA State Medical License 2007 - 2026
NY State Medical License 2000 - 2008
American Board of Psychiatry and Neurology Neurology

Clinical Trials

Longitudinal At Home Smell Testing to Detect Infection by SARS-CoV-2 Start of enrollment: 2022 Nov 14
Recruiting
Roles: Principal Investigator, Contact
Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD Start of enrollment: 2023 May 09
Recruiting
Roles: Principal Investigator, Contact

Publications & Presentations

PubMed

Neuronal STING activation in amyotrophic lateral sclerosis and frontotemporal dementia.
Christine Marques, Aaron Held, Katherine Dorfman, Joon Sung, Catherine Song, Amey S Kavuturu, Corey Aguilar, Tommaso Russo, Derek H Oakley, Mark W Albers, Bradley T Hy...> ;Acta Neuropathologica. 2024 Mar 13
causalCmprsk: An R package for nonparametric and Cox-based estimation of average treatment effects in competing risks data.
Bella Vakulenko-Lagun, Colin Magdamo, Marie-Laure Charpignon, Bang Zheng, Mark W Albers, Sudeshna Das> ;Computer Methods and Programs in Biomedicine. 2023 Dec 1
18 citations
Causal inference in medical records and complementary systems pharmacology for metformin drug repurposing towards dementia.
Marie-Laure Charpignon, Bella Vakulenko-Lagun, Bang Zheng, Colin Magdamo, Bowen Su, Kyle Evans, Steve Rodriguez, Artem Sokolov, Sarah Boswell, Yi-Han Sheu, Melek Somai...> ;Nature Communications. 2022 Dec 10
1 citations
Olfactory Function and Markers of Brain Pathology in Non-Demented Individuals with Autosomal Dominant Alzheimer's Disease.
Liliana Ramirez-Gomez, Mark W Albers, Ana Baena, Clara Vila-Castelar, Joshua T Fox-Fuller, Justin Sanchez, Felipe Jain, Alefiya D Albers, Francisco Lopera, Yakeel T Qu...> ;Journal of Alzheimer's Disease. 2022 Jan 1
40 citations
International consensus statement on allergy and rhinology: Olfaction.
Zara M Patel, Eric H Holbrook, Justin H Turner, Nithin D Adappa, Mark W Albers, Aytug Altundag, Simone Appenzeller, Richard M Costanzo, Ilona Croy, Greg E Davis, Puya ...> ;International Forum of Allergy & Rhinology. 2022 Apr 1
91 citations
Post-viral effects of COVID-19 in the olfactory system and their implications.
Michael S Xydakis, Mark W. Albers, Eric H. Holbrook, Dina M Lyon, Robert Y Shih, Johannes Frasnelli, Axel Pagenstecher, Alexandra Kupke, Lynn W. Enquist, Stanley Perlman> ;The Lancet. Neurology. 2021 Sep 1
19 citations
Genome-encoded cytoplasmic double-stranded RNAs, found in C9ORF72 ALS-FTD brain, propagate neuronal loss
Steven Rodriguez, Asli Sahin, Benjamin R. Schrank, Hawra Al-Lawati, Isabel Costantino, Eric B. Benz, Darian Fard, Alefiya Dhilla Albers, Luxiang Cao, Alexis C. Gomez, ...> ;Science Translational Medicine. 2021 Jul 7
16 citations
Systematic in silico analysis of clinically tested drugs for reducing amyloid-beta plaque accumulation in Alzheimer's disease.
Kumpal Madrasi, Raibatak Das, Hafiz Mohmmadabdul, Lin Lin, Bradley T. Hyman, Douglas A. Lauffenburger, Mark W. Albers, Robert A. Rissman, John M. Burke, Joshua F. Apga...> ;Alzheimer's & Dementia. 2021 May 2
85 citations
Machine learning identifies candidates for drug repurposing in Alzheimer's disease.
Steven Rodriguez, Clemens B. Hug, Petar Todorov, Nienke Moret, Sarah A. Boswell, Kyle Evans, George Zhou, Nathan T. Johnson, Bradley T. Hyman, Peter K. Sorger, Mark W....> ;Nature Communications. 2021 Feb 15
196 citations
COVID-19 and the Chemical Senses: Supporting Players Take Center Stage.
Keiland W. Cooper, David H. Brann, Michael C. Farruggia, Surabhi Bhutani, Robert Pellegrino, Tatsuya Tsukahara, Caleb Weinreb, Paule V. Joseph, Eric D. Larson, Valenti...> ;Neuron. 2020 Jul 22
33 citations
Innate immune signaling in the olfactory epithelium reduces odorant receptor levels: modeling transient smell loss in COVID-19 patients
Steven Rodriguez, Luxiang Cao, Gregory T. Rickenbacher, Eric G. Benz, Colin Magdamo, Liliana Ramirez Gomez, Eric H. Holbrook, Alefiya Dhilla Albers, Rose Gallagher, M....> ;Medrxiv. 2020 Jun 16
42 citations
Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription.
Jaehong Suh, Donna M. Romano, Larissa Nitschke, Scott P. Herrick, Britt A. DiMarzio, Volodymyr Dzhala, Jun Seok Bae, Mary K. Oram, Yuejiao Zheng, Basavaraj Hooli, Kris...> ;Cell. 2019 Aug 22
26 citations
A dynamic view of the proteomic landscape during differentiation of ReNcell VM cells, an immortalized human neural progenitor line
Yuyu Song, Kartik Subramanian, Matthew J. Berberich, Steven Rodriguez, Isabel J. Latorre, Catherine M. Luria, Robert A. Everley, Mark W. Albers, Timothy J. Mitchison, ...> ;Scientific Data. 2019 Feb 19
4 citations
Olanzapine Improved Symptoms and Olfactory Function in an Olfactory Reference Syndrome Patient
Alefiya Dhilla Albers, Ilaria Amato, Mark W. Albers> ;The Journal of Neuropsychiatry and Clinical Neurosciences. 2017 Nov 14
4 citations
Activity-Dependent Dysfunction in Visual and Olfactory Sensory Systems in Mouse Models of Down Syndrome.
Christopher William, Lubna Saqran, Matthew A. Stern, Charles L. Chiang, Scott P. Herrick, Aziz Rangwala, Mark W. Albers, Matthew P. Frosch, Bradley T. Hyman> ;The Journal of Neuroscience. 2017 Sep 12
111 citations
Prediction of cognition in Parkinson's disease with a clinical-genetic score : a longitudinal analysis of nine cohorts
Ganqiang Liu, Joseph J. Locascio, Jean-Christophe Corvol, Brendon P. Boot, Zhixiang Liao, Kara Page, Daly Franco, Kyle Burke, Iris E. Jansen, Ana Trisini-Lipsanopoulos...> ;The Lancet. Neurology. 2017 Aug 1
9 citations
Nasal neuron PET imaging quantifies neuron generation and degeneration
Genevieve C. Van de Bittner, Misha M. Riley, Luxiang Cao, Janina Ehses, Scott P. Herrick, Emily L. Ricq, Hsiao-Ying Wey, Michael J. O'Neill, Zeshan Ahmed, Tracey K. Mu...> ;The Journal of Clinical Investigation. 2017 Feb 1
29 citations
Episodic memory of odors stratifies Alzheimer biomarkers in normal elderly.
Alefiya Dhilla Albers, Josephine Asafu-Adjei, Mary K. Delaney, Kathleen Kelly, Teresa Gomez-Isla, Deborah Blacker, Keith A. Johnson, Reisa A. Sperling, Bradley T. Hyma...> ;Annals of Neurology. 2016 Oct 1
684 citations
Tau positron emission tomographic imaging in aging and early Alzheimer disease
Philiossaint Elia, M., Keith A. Johnson, Aaron P. Schultz, Rebecca A. Betensky, J. Alex Becker, Jorge Sepulcre, Dorene M. Rentz, Elizabeth C. Mormino, Jasmeer P. Chha...> ;Annals of Neurology. 2016 Jan 1
5 citations
Massachusetts Alzheimer's Disease Research Center: progress and challenges.
Bradley T. Hyman, John H. Growdon, Mark W. Albers, Randy L. Buckner, Jasmeer P. Chhatwal, Maria Teresa Gomez-Isla, Christian Haass, Eloise Hudry, Clifford R. Jack, Kei...> ;Alzheimer's & Dementia. 2015 Oct 1
98 citations
Odor identification and Alzheimer disease biomarkers in clinically normal elderly
Matthew E. Growdon, Aaron P. Schultz, Alexander Dagley, Rebecca E. Amariglio, Trey Hedden, Dorene M. Rentz, Keith A. Johnson, Reisa A. Sperling, Mark W. Albers, Gad A....> ;Neurology. 2015 May 26
348 citations
At the interface of sensory and motor dysfunctions and Alzheimer's disease
Mark W. Albers, Grover C. Gilmore, Jeffrey Kaye, Claire Murphy, Arthur Wingfield, David A. Bennett, Adam L. Boxer, Aron S. Buchman, Karen J. Cruickshanks, Davangere P....> ;Alzheimer's & Dementia. 2015 Jan 1
15 citations
Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology.
Amy M. Pooler, Manuela Polydoro, Susanne Wegmann, Rose Pitstick, Kevin R Kay, Laura Sanchez, George A. Carlson, Teresa Gomez-Isla, Mark W. Albers, Tara L. Spires-Jones...> ;The Journal of Comparative Neurology. 2013 Dec 15
Studies of pear-shaped nuclei using accelerated radioactive beams.
Gaffney LP, Butler PA, Scheck M, Hayes AB, Wenander F, Albers M, Bastin B, Bauer C, Blazhev A, Bönig S, Bree N, Cederkäll J, Chupp T, Cline D, Cocolios TE, Davinson T,...> ;Nature. 2013-05-09
14 citations
Loss of the V-ATPase B1 Subunit Isoform Expressed in Non-Neuronal Cells of the Mouse Olfactory Epithelium Impairs Olfactory Function
Teodor G. Păunescu, Steven Rodriguez, Eric B. Benz, Mary McKee, Robert Tyszkowski, Mark W. Albers, Dennis Brown> ;Plos One. 2012 Sep 20
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Press Mentions

Long Covid Could Reveal Clues to Alzheimer’s, Lyme DiseaseMarch 17th, 2022
Engaging AI in the Battle Against Alzheimer’sMarch 4th, 2021
AI and Alzheimer's DiseaseMarch 4th, 2021
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Grant Support

The Olfactory Neural Circuit As A Systems Level Model Of Neurodegenerative DiseasOffice Of The Director, National Institutes Of Health2009
Mapping Molecular And Cellular Responses To OdorantsNational Institute On Deafness And Other Communication Disorders2001–2005