MarkBrownMD

PubMed

• Pooled analysis of tanezumab efficacy and safety with subgroup analyses of phase III clinical trials in patients with osteoarthritis pain of the knee or hip.
  Tive, L.,Bello, A. E.,Radin, D.,Schnitzer, T. J.,Nguyen, H.,Brown, M. T.,West, C. R.> ;J Pain Res. 2019 Apr 03
• First-in-human randomized clinical trials of the safety and efficacy of tanezumab for treatment of chronic knee osteoarthritis pain or acute bunionectomy pain.
  Walicke, P. A.,Hefti, F.,Bales, R.,Lu, S. P.,Ruckle, J. L.,Brown, M. T.,West, C. R.,Shelton, D. L.> ;Pain Rep. 2018 Jun 21
• Development of pain therapies targeting nerve growth factor signal transduction and the strategies used to resolve safety issues.
  Bélanger, P.,West, C. R.,Brown, M. T.> ;J Toxicol Sci. 2018 Feb 09
• Safety and efficacy of subcutaneous tanezumab in patients with knee or hip osteoarthritis.
  Birbara, C.,Dabezies, E. J.,Burr, A. M.,Fountaine, R. J.,Smith, M. D.,Brown, M. T.,West, C. R.,Arends, R. H.,Verburg, K. M.> ;J Pain Res. 2018 Feb 02
• Gradual Implementation of the Meiotic Recombination Program via Checkpoint Pathways Controlled by Global DSB Levels.
  Joshi, N.,Brown, M. S.,Bishop, D. K.,Börner, G. V.> ;Mol. Cell. 2015 Feb 11
• Exploring the Role of Tanezumab as a Novel Treatment for the Relief of Neuropathic Pain.
  Bramson, C.,Herrmann, D. N.,Carey, W.,Keller, D.,Brown, M. T.,West, C. R.,Verburg, K. M.,Dyck, P. J.> ;Pain Med. 2015 Jan 17
• DNA Strand Exchange and RecA Homologs in Meiosis.
  Brown, M. S.,Bishop, D. K.> ;Cold Spring Harb Perspect Biol. 2014 Dec 06
• Nerve safety of tanezumab, a nerve growth factor inhibitor for pain treatment.
  Brown, M. T.,Herrmann, D. N.,Goldstein, M.,Burr, A. M.,Smith, M. D.,West, C. R.,Verburg, K. M.,Dyck, P. J.> ;J. Neurol. Sci.. 2014 Jul 31
• Efficacy and Safety of Intravenous Tanezumab for the Symptomatic Treatment of Osteoarthritis: 2 Randomized Controlled Trials versus Naproxen.
  Ekman, E. F.,Gimbel, J. S.,Bello, A. E.,Smith, M. D.,Keller, D. S.,Annis, K. M.,Brown, M. T.,West, C. R.,Verburg, K. M.> ;J. Rheumatol.. 2014 Oct 03
• Efficacy and safety of tanezumab added on to diclofenac sustained release in patients with knee or hip osteoarthritis: a double-blind, placebo-controlled, parallel-gro...
  Balanescu, A. R.,Feist, E.,Wolfram, G.,Davignon, I.,Smith, M. D.,Brown, M. T.,West, C. R.> ;Ann. Rheum. Dis.. 2013 Jul 16
• A phase III placebo- and oxycodone-controlled study of tanezumab in adults with osteoarthritis pain of the hip or knee: Response to letter to the editor.
  Spierings, E. L.,Fidelholtz, J.,Wolfram, G.,Smith, M. D.,Brown, M. T.,West, C. R.> ;Pain. 2014 Sep 10
• The Third Exon of the Budding Yeast Meiotic Recombination Gene HOP2 Is Required for Calcium-dependent and Recombinase Dmc1-specific Stimulation of Homologous Strand As...
  Chan, Y. L.,Brown, M. S.,Qin, D.,Handa, N.,Bishop, D. K.> ;J. Biol. Chem.. 2014 May 07
• Long-term safety and effectiveness of tanezumab as treatment for chronic low back pain.
  Gimbel, J. S.,Kivitz, A. J.,Bramson, C.,Nemeth, M. A.,Keller, D. S.,Brown, M. T.,West, C. R.,Verburg, K. M.> ;Pain. 2014 Jun 18
• Efficacy and safety of tanezumab monotherapy or combined with non-steroidal anti-inflammatory drugs in the treatment of knee or hip osteoarthritis pain.
  Schnitzer, T. J.,Ekman, E. F.,Spierings, E. L.,Greenberg, H. S.,Smith, M. D.,Brown, M. T.,West, C. R.,Verburg, K. M.> ;Ann. Rheum. Dis.. 2014 Mar 15
• 100 citations
  Tanezumab reduces osteoarthritic hip pain: results of a randomized, double-blind, placebo-controlled phase III trial.
  Mark T. Brown, Frederick T. Murphy, David M. Radin, Isabelle Davignon, Michael D. Smith, Christine R. West> ;Arthritis and Rheumatism. 2013 Jul 1
• 159 citations
  Tanezumab reduces osteoarthritic knee pain: results of a randomized, double-blind, placebo-controlled phase III trial.
  Mark T. Brown, Frederick T. Murphy, David M. Radin, Isabelle Davignon, Michael D. Smith, Christine R. West> ;The Journal of Pain. 2012 Aug 1
• 7 citations
  Utility of quantitative computerized pain drawings in a sample of spinal stenosis patients.
  Elizabeth R. Felix, Karina Galoian, Chad Aarons, Mark D. Brown, Stephen A. Kearing, Uwe Heiss> ;Pain Medicine. 2010 Mar 1
• Multiple-day efficacy of parecoxib sodium treatment in postoperative bunionectomy pain.
  Apfelbaum, J. L.,Desjardins, P. J.,Brown, M. T.,Verburg, K. M.> ;Clin J Pain. 2008 Oct 22
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