MarkIGreeneMD

PubMed

• 1 citations
  Challenges in Detection of Serum Oncoprotein: Relevance to Breast Cancer Diagnostics.
  Justin Lengfeld, Hongtao Zhang, Steven Stoesz, Ramachandran Murali, Franklin Pass, Mark I. Greene, Peeyush N. Goel, Payal Grover> ;Breast Cancer. 2021 Oct 14
• 45 citations
  Regulatory T Cells: Regulation of Identity and Function.
  Payal Grover, Peeyush N. Goel, Mark I. Greene> ;Frontiers in Immunology. 2021 Oct 5
• Rational Design of Constrained Peptides as Protein Interface Inhibitors
  Ramachandran Murali, Hongtao Zhang, Zheng Cai, Lian Lam, Mark I. Greene> ;Antibodies. 2021 Aug 16
• 3 citations
  Disabling the Nuclear Translocalization of RelA/NF-κB by a Small Molecule Inhibits Triple-Negative Breast Cancer Growth
  Hirotaka Kanzaki, Avradip Chatterjee, Hanieh Hossein Nejad Ariani, Xinfeng Zhang, Stacey Chung, Nan Deng, V. Krishnan Ramanujan, Xiaojiang Cui, Mark I. Greene, Ramacha...> ;Breast Cancer. 2021 Jul 5
• 8 citations
  Epithelial cell transforming 2 is regulated by Yes-associated protein 1 and mediates pancreatic cancer progression and metastasis.
  Ce Li, Zhenzi Peng, Yizhou Wang, Gloria Lam, Nicholas N. Nissen, Jie Tang, Xiaopu Yuan, Michael R. Lewis, Mark I. Greene, Stephen J. Pandol, Qiang Wang> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2021 Jan 27
• 19 citations
  Th1 cytokine interferon gamma improves response in HER2 breast cancer by modulating the ubiquitin proteasomal pathway
  Yongsheng Jia, Krithika Kodumudi, Ganesan Ramamoorthi, Amrita Basu, Colin Snyder, Doris Wiener, Shari Pilon-Thomas, Payal Grover, Hongtao Zhang, Mark I. Greene, Qianxi...> ;Molecular Therapy. 2021 Jan 5
• 6 citations
  FOXP3 and Tip60 Structural Interactions Relevant to IPEX Development Lead to Potential Therapeutics to Increase FOXP3 Dependent Suppressor T Cell Functions.
  Payal Grover, Peeyush N. Goel, Ciriaco A. Piccirillo, Mark I. Greene> ;Frontiers in Pediatrics. 2021 Jan 1
• A Structure-Guided Delineation of FOXP3 Regulation Mechanism in IPEX.
  Tengyun Ma, Xiaomin Song, Ciriaco A. Piccirillo, Guoping Deng, Mark I. Greene> ;Advances in Experimental Medicine and Biology. 2021 Jan 1
• 22 citations
  Structural Features and PF4 Functions that Occur in Heparin-Induced Thrombocytopenia (HIT) Complicated by COVID-19
  Zheng Cai, Mark I. Greene, Zhiqiang Zhu, Hongtao Zhang> ;Antibodies. 2020 Oct 10
• 31 citations
  PRMT5 Is Required for T Cell Survival and Proliferation by Maintaining Cytokine Signaling.
  Yukinori Tanaka, Yasuhiro Nagai, Mariko Okumura, Mark I. Greene, Taku Kambayashi> ;Frontiers in Immunology. 2020 Apr 9
• 26 citations
  FoxP3 in Treg cell biology: a molecular and structural perspective.
  Guoping Deng, X Song, Mark I. Greene> ;Clinical and Experimental Immunology. 2020 Mar 1
• 7 citations
  PRMT5 and Tip60 Modify FOXP3 Function in Tumor Immunity.
  Peeyush N. Goel, Payal Grover, Mark I. Greene> ;Critical Reviews in Immunology. 2020 Jan 1
• 83 citations
  Foxp3 Post-translational Modifications and Treg Suppressive Activity.
  Guoping Deng, Xiaomin Song, Shigeyoshi Fujimoto, Ciriaco A. Piccirillo, Yasuhiro Nagai, Mark I. Greene> ;Frontiers in Immunology. 2019 Oct 18
• 35 citations
  Sequential Anti-PD1 Therapy Following Dendritic Cell Vaccination Improves Survival in a HER2 Mammary Carcinoma Model and Identifies a Critical Role for CD4 T Cells in ...
  Krithika Kodumudi, Ganesan Ramamoorthi, Colin Snyder, Amrita Basu, Yongsheng Jia, Sabrina Awshah, Amber Beyer, Doris Wiener, Lian Lam, Hongtao Zhang, Mark I. Greene, R...> ;Frontiers in Immunology. 2019 Aug 14
• 48 citations
  PRMT5 Associates With the FOXP3 Homomer and When Disabled Enhances Targeted p185erbB2/neu Tumor Immunotherapy
  Yasuhiro Nagai, Mei Q. Ji, Fuxiang Zhu, Yan Xiao, Yukinori Tanaka, Taku Kambayashi, Shigeyoshi Fujimoto, Michael M. Goldberg, Hongtao Zhang, Bin Li, Takuya Ohtani, Mar...> ;Frontiers in Immunology. 2019 Feb 8
• 32 citations
  Novel TNF Receptor-1 Inhibitors Identified as Potential Therapeutic Candidates for Traumatic Brain Injury
  Rachel K. Rowe, Jordan L. Harrison, Hongtao Zhang, Adam D. Bachstetter, David P. Hesson, Bruce F. O'Hara, Mark I. Greene, Jonathan Lifshitz> ;Journal of Neuroinflammation. 2018 May 22
• 8 citations
  A spliced form of CD44 expresses the unique glycan that is recognized by the prostate cancer specific antibody F77.
  Xi Chen, Yasuhiro Nagai, Zhiqiang Zhu, Hang Ruan, Donna M. Peehl, Mark I. Greene, Hongtao Zhang> ;Oncotarget. 2018 Jan 9
• 38 citations
  Suppression by human FOXP3(+) regulatory T cells requires FOXP3-TIP60 interactions.
  Khalid Bin Dhuban, Eva d'Hennezel, Yasuhiro Nagai, Yan Xiao, Steven Shao, Roman Istomine, Fernando Alvarez, Moshe Ben-Shoshan, Hans D. Ochs, Bruce Mazer, Bin Li, Chiyo...> ;Science Immunology. 2017 Jun 16
• 10 citations
  A targeted immunotherapy approach for HER2/neu transformed tumors by coupling an engineered effector domain with interferon-γ.
  Hongtao Zhang, Lian Lam, Yasuhiro Nagai, Zhiqiang Zhu, Xi Chen, Mei Q. Ji, Mark I. Greene> ;Oncoimmunology. 2017 Mar 17
• Peter C. Nowell (1928-2016).
  Mark I. Greene, Jonni S. Moore> ;Science. 2017 Mar 3
• 14 citations
  Atomic features of an autoantigen in heparin-induced thrombocytopenia (HIT).
  Zheng Cai, Zhiqiang Zhu, Mark I. Greene, Douglas B. Cines> ;Autoimmunity Reviews. 2016 Jul 1
• 76 citations
  Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis.
  Susan Morvaridi, Deepti Dhall, Mark I. Greene, Stephen J. Pandol, Qiang Wang> ;Scientific Reports. 2015 Nov 16
• 17 citations
  Disabling of the erbB Pathway Followed by IFN-γ Modifies Phenotype and Enhances Genotoxic Eradication of Breast Tumors
  Yasuhiro Nagai, Hiromichi Tsuchiya, E. Aaron Runkle, Peter D. Young, Mei Q. Ji, Larry Norton, Jeffrey A. Drebin, Hongtao Zhang, Mark I. Greene> ;Cell Reports. 2015 Sep 29
• 85 citations
  Atomic description of the immune complex involved in heparin-induced thrombocytopenia.
  Zheng Cai, Serge Yarovoi, Zhiqiang Zhu, Lubica Rauova, Vincent Hayes, Tatiana Lebedeva, Qun Liu, Mortimer Poncz, Gowthami M. Arepally, Douglas B. Cines, Mark I. Greene> ;Nature Communications. 2015 Sep 22
• 56 citations
  Pim-2 Kinase Influences Regulatory T Cell Function and Stability by Mediating Foxp3 Protein N-terminal Phosphorylation.
  Guoping Deng, Yasuhiro Nagai, Yan Xiao, Zhiyuan Li, Shujia Dai, Takuya Ohtani, Alison H. Banham, Bin Li, Shiaw-Lin Wu, Wayne W. Hancock, Arabinda Samanta, Hongtao Zhan...> ;The Journal of Biological Chemistry. 2015 Aug 14
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Journal Articles

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  Zhang, H., Lam, L., Nagai, Y., Zhu, Z., Chen, X., Ji, MQ, and Greene, MI, Oncoimmunology, 1/17/2017
• Suppression by human FOXP3+ regulatory T cells requires FOXP3-TIP60 interactions  
  Bin Dhuban K, d'Hennezel E, Nagai Y, Xiao Y, Shao S, Istomine R, Alvarez F, Ben-Shoshan M, Ochs H, Mazer B, Li B, Sekine C, Berezov A, Hancock W, Torgerson TR, Greene ..., Sci Immunol, 1/1/2017
• Atomic Description of the Immune Complex involved in Heparin-Induced Thrombocytopenia (HIT)  
  Cai Z, Yarovoi SV, Zhu Z, Rauova L, Hayes V, Lebedeva T, Liu Q, Poncz M, Arepally G, Cines DB, and Greene MI, Nature Communications, 1/22/2015
• FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3  
  Wang L, Liu Y, Han R, Beier UH, Bhatti TR, Akimova T, Greene MI, Hiebert SW, Hancock WW, J Clin Invest, 1/1/2015
• Pim-2 kinase influences Tregulatory cell function and stability by mediating Foxp3 N-terminal phosphorylation  
  Deng G, Nagai Y, Xiao Y, Li Z, Dai S, Ohtani T, Banham A, Li B, Wu SL, Hancock W, Samanta A, Zhang H, Greene MI, J Biol Chem, 1/1/2015
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  Nagai Y, Tsuchiya H, Runkle EA, Young PD, Ji MQ, Norton L, Drebin JA, Zhang H, Greene MI, Cell Reports, 1/1/2015
• Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis  
  Morvaridi S, Dhall D, Greene MI, Pandol SJ, Wang Q, Scientific Reports, 1/1/2015
• In vivo molecular imaging of HER2 expression in a rat model of Barrett's esophagus adenocarcinoma  
  Realdon S, Dassie E, Fassan M, Dall'olmo L, Hatem G, Buda A, Arcidiacono D, Diamantis G, Zhang H, Greene MI, Sturniolo GC, Rugge M, Alberti A, Battaglia G, Dis Esophagus, 1/7/2014
• Carbohydrate sequence of the prostate cancer-associated antigen F77 assigned by a mucin O-glycome designer array  
  Gao C, Liu Y, Zhang H, Zhang Y, Fukuda MN, Palma AS, Kozak RP, Childs RA, Nonaka M, Li Z, Siegel DL, Hanfland P, Peehl DM, Chai W, Greene MI, Feizi T, J Biol Chem, 1/1/2014
• Dynamic Interactions Between TIP60 and p300 Regulate FOXP3 Function Through a Structural Switch Defined by a Single Lysine on TIP60  
  Xiao Y, Nagai Y, Deng G., Ohtani T., Zhu Z., Zhou Z., Zhang H., Ji M.Q., Hancock W.W., Samanta A., Lough J.W., and Greene M.I., Cell Reports, 1/1/2014
• Determination of Carbohydrate Structure Recognized by Prostate-specific F77 Monoclonal Antibody through Expression Analysis of Glycosyltransferase Genes  
  Nonaka M, Fukuda MN, Gao C, Li Z, Zhang H, Greene MI, Peehl DM, Feizi T, Fukuda M, J Biol Chem, 1/1/2014
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  Liu Q, Guo Y, Chang Y, Cai Z, Assur Z, Mancia F, Greene MI, Hendrickson WA, Acta Crystallogr D Biol Crystallogr, 1/1/2014
• Structural and biochemical studies of RIG-I antiviral signaling  
  Feng M., Ding Z., Xu L., Kong L., Wang W., Jiao S., Shi Z., Greene M.I., Cong Y., and Zhou Z, Protein Cell, 1/1/2013
• Garcinol induces lysosome-dependent p300/FOXP3 degradation and limits Treg cell functions to enhance targeted therapy against cancers  
  Du T, Nagai Y, Xiao Y, Greene MI, Zhang H, Exp Mol Pathol, 1/1/2013
• Structure of Sad1-UNC84 homology (SUN) domain defines features of molecular bridge in nuclear envelope  
  Zhou Z., Du X., Cai Z., Song X., Zhang H., Murali R., Greene M.I., and Wang Q, Journal of Biological Chemistry, 1/1/2012
• A structural modulator of tumor necrosis factor type 1 receptor promotes bone formation under lipopolysaccharide-induced inflammation in a murine tooth extraction model  
  Nakachi H, Aoki K, Tomomatsu N, Alles N, Nagano K, Yamashiro M, Zhang H, Murali R, Greene MI, Ohya K, Amagasa T, Eur J Pharmacology, 1/1/2012
• The OPCML Tumor Suppressor Functions as a Cell Surface Repressor-Adaptor, Negatively Regulating Receptor Tyrosine Kinases in Epithelial Ovarian Cancer  
  McKie AB, Vaughan S, Zanini E, Okon IS, Louis L, de Sousa C, Greene MI, Wang Q, Agarwal R, Shaposhnikov D, Wong JL, Gungor H, Janczar S, El-Bahrawy M, Lam EW, Chayen N..., Cancer Discovery, 1/1/2012
• Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function  
  Song X., Li B., Wang Q., Berezov A., Xu C., Cai Z., Zhang H. Zhou Z., and Greene M.I., Cell Reports, 1/1/2012
• YAP modifies cancer cell sensitivity to EGFR and surviving inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase  
  Huang JM, Nagatomo I., Suzuki E., Mizuno T., Kumagai T., Berezov A., Zhang H., Karlan B., Greene M.I. and Wang Q., Oncogene, 1/1/2012
• Molecular and biological role of the FOXP3 N-terminal domain in immune regulation by T regulatory/ suppressor cells  
  Deng G., Xiao Y., Zhou Z., Nagai, Y.,1 Zhang, H., Li B.,3 and Greene MI, Experimental and Molecular Pathology, 1/1/2012
• Structural insights into SUN-KASH complexes across the nuclear envelope  
  Wang W., Shi Z., Jiao S., Chen C., Wang H., Liu G., Wang Q., Zhao Y., Greene MI, Zhou Z, Cell Research, 1/1/2012
• MDM2 regulates a novel form of incomplete neoplastic transformation of Theileria parva infected lymphocytes  
  Hayashida K., Kajino K., Hattori M., Wallace M., Morrison I., Greene M.I., and Sugimoto, C, Experimental and Molecular Pathology, 1/1/2012
• Mutations in K-Ras linked to levels of osteoprotegerin and sensitivity to TRAIL-induced cell death in pancreatic ductal adenocarcinoma cells  
  Kanzaki H., Ohtaki A., Merchant F.K., Greene M.I., and Murali, R, Experimental and Molecular Pathology, 1/1/2012
• Structure Based Antibody-Like Peptidomimetics  
  Murali R., Greene M.I., Pharmaceuticals, 1/1/2012
• Germinal center kinases in immune regulation  
  Yin H., Shi Z., Jiao S., Chen C., Wang W., Greene M.I., and Zhou Z, Cellular and Molecular Immunology, 1/1/2012
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Books/Book Chapters

• Cancer Immunotherapy: Immune Suppression and Tumor Growth 
  Chapter: Monoclonal antibodies for cancer therapy and prevention: paradigm studies in targeting the neu/ERBB2/HER2 oncoprotein 
  Zhang H., Samanta A., Nagai,Y., Tsuchiya H., Ohtani T., Cai Z., Zhu Z., Liu J., and Greene M.I.Editors: George C. Prendergast and Elizabeth M. Jaffee.Academic PressEdition 2nd,2012
• Brenner’s Online Encyclopedia of Genetics 
  Chapter: The neu oncogene 
  Wang Q. and Greene M. I.Edition 2nd,2011
• The Immune System as a Novel Target for Therapy 
  Chapter: FOXP3 biochemistry will lead to novel drug approaches for vaccines and diseases that lack suppressor T cells 
  Editors: Luis Graca.2008
• Progress in Inflammation Research 
  Chapter: The immune synapse as a novel target for therapy 
  Li B, Greene MIEditors: Parnham, M.J..2007
• Encyclopedia of Cancer 
  Chapter: Her2/neu 
  Brennan, P. and Greene, M.I.2002
• The Immunoglobulins 
  Chapter: From monoclonal antibodies to small peptides and mimetics: size and reduction of the binding site in the immunoglobulin superfamily 
  Zerva, L., Cotsarelis, G., and Greene, M.I.1997
• Encyclopedia of Cancer 
  Chapter: Her2/neu, A Receptor Tyrosine Kinase with Developmental and Oncogenic Activity 
  Qian, X., and Greene, M.I.Academic Press1997
• Handbook of Experimental Immunology 
  Chapter: The design of biologically active small molecular forms derived from functional anti-receptor antibodies 
  Maier, C.C., Zhang, X., and Greene, M.I.Blackwell Science, Cambridge, MAEdition 5th,1996
• Encyclopedia of Virology 
  Chapter: Viral receptors 
  H.U. Saragovi, G.J. Sauvé, and M.I. GreeneEditors: Robert G. Webster and Allan Granoff.Saunders Scientific Publications, London1992
• Molecular evolution on rugged landscapes: Proteins RNA and the Immune System 
  Chapter: Use of antibodies as molecular mimics to probe intermolecular interaction landscapes 
  Williams, W.V., Kieber-Emmons, T., Weiner, D.B., Greene, M.IEditors: A. Perelson and S. Kauffman.Addison Wesley Longman1991
• Monoclonal Antibodies: Application and Clinical Oncology 
  Chapter: Anti-receptor antibody structure and peptide design 
  Kieber-Emmons, T., Williams, W.V., and Greene, M.I.Editors: A. A. Epenetos.Chapman and Hall Medical1991
• Chemical Immunology 
  Chapter: Structure and Regulation of Internal Image Idiotypes 
  Williams, W.V., Guy, R.H., Cohen, J.A., Weiner, D.B. and Greene, M.I.1990
• Methods in Enzymology 
  Chapter: Development and Use of Anti-Receptor Antibodies to Study Interaction of Mammalian Reovirus Type 3 with its Cell Surface Receptor 
  Williams, W.V., Weiner, D.B. and Greene, M.I.1989
• Chemical Immunology 
  Chapter: Molecular Aspects of Ligand Interaction with Somatic and Immune Receptors: Insights from Studies of the Mammalian Reoviruses 
  Cohen, J.A., Williams, W. V., Weiner, D. B., Greene, M. I.1989
• Immune System and Cancer 
  Chapter: The role of the neu Oncogene Product in Cell Transformation and Normal Development 
  Kokai, Y., Wada, T., Myers, J., Brown, V., Dobashi, K., Cohen, J., Hamuro, J., Weiner, D., and Greene, M.I.Editors: T Hamaoka et al.Japan Society Press1989
• Host Response to Viruses Immunological Diseases 
  Greene, M.I. and Fields, B.N.Editors: M. Frank.1988
• Advances in Neuroblastoma Research 
  Chapter: The neu oncgene in human neuroblastoma cell lines 
  Maguire, H.C., Sibinga, E., Weiner, D.B., and Greene, M.I.Alan R. Liss, Inc.1988
• Anti-Idiotypes, Receptors and Molecular Mimicry 
  Chapter: Regulation of Cell Growth and Immunity by Reovirus Anti-Receptor Antibodies 
  Gaulton, G.N. and Greene, M.I.Editors: D.S. Linthicum, N.R. Farid.1988
• Advances in Vaccine Development 
  Chapter: Determination of the Neutralizing/Cell-Attachment Epitope of Reovirus Type 3. Technol. 
  Williams, W.V., Weiner, D.B., Rubin, D.H., Guy, H.R. and Greene, M.I.1988
• Therapeutic Advances in Clin. Immunology 
  Chapter: Vaccine Development 
  Greene, M.I.1988
• Monoclonal Antibodies and Cancer Therapy 
  Chapter: Use of monoclonal anti-idiotypic antibodies as specific vaccines and as probes of the mammalian reovirus type 3 receptor 
  Gaulton, G.N., Co, M.S., and Greene, M.IEditors: R. Reisfeld, Sell, S.Liss Publ., New York1988
• Induction and Recognition of the Transformed Cell 
  Greene, M.I. and Hamaoka, TPlenum Press1987
• Regulation of Immune Response by In Vivo Admininistration of Monoclonal Anti I-A Antibodies 
  Chapter: Anti-IA antibodies in the Treatment of Autoimmune Disease 
  Carroll, A.M., Perry, L.L., Lowy, A. and Greene, M.I.Editors: J. Clot and J. Sany.Academic Press Inc.1986
• Immunological Investigations 
  Chapter: Anti-idiotypic Antibodies and Disease 
  Monroe, John G. and Greene, M.I.1986
• Lymphokines 
  Chapter: Defective antigen presenting cell function and Interleukins 
  Granstein, R.D., Tominaga, A., Mizel, S.B., and Greene, M.I.Editors: S. Mizel.1985
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Other

• Suppressor T cell and their factors in the S1509a tumor bearing A/Jax mouse host. Ph.D. Thesis 
  Greene, M.I., University of Manitoba
  1/1/1977