MarkAKleinMD

PubMed

• Targeting RET alterations in non-small cell lung cancer.
  Go Nishikawa, Mark A Klein> ;Current Problems in Cancer. 2024 Mar 16
• 1 citations
  Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes.
  Wu, H., Kren, B., Lane, A., Cassel, T., Higashi, R., Fan, T., Scaria, G., Shekels, L., Klein, M., Albrecht, J.> ;The Journal of Biological Chemistry. 2023 Dec 1
• 1 citations
  Trajectory of Healthcare Contact Days for Veterans With Advanced Gastrointestinal Malignancy.
  Whitney V Johnson, Quan H Phung, Vishal R Patel, Alexander K Tsai, Nivedita Arora, Mark A Klein, Anders D Westanmo, Anne H Blaes, Arjun Gupta> ;The Oncologist. 2024 Feb 2
• Gross Hematuria and Lower Urinary Tract Symptoms Associated With Military Burn Pits Exposures in US Veterans Deployed to Iraq and Afghanistan.
  Mosammat M Perveen, Henry E Mayo-Malasky, Mary F Lee-Wong, Julie M Tomaska, Edward Forsyth, Amy Gravely, Mark A Klein, Janeen H Trembley, Tammy A Butterick, Robert A P...> ;Journal of Occupational and Environmental Medicine. 2023 Sep 1
• 1 citations
  Inhibition of Mitochondrial Antioxidant Defense and CDK4/6 in Mesothelioma.
  Marian Kratzke, George Scaria, Stephen Porter, Betsy Kren, Mark A Klein> ;Molecules. 2023 May 27
• 1 citations
  Targeting Protein-Protein Interactions to Inhibit Cyclin-Dependent Kinases.
  Mark Klein> ;Pharmaceuticals. 2023 Mar 31
• 1 citations
  Correction: Protein kinase CK2 - diverse roles in cancer cell biology and therapeutic promise.
  Janeen H Trembley, Betsy T Kren, Muhammad Afzal, George A Scaria, Mark A Klein, Khalil Ahmed> ;Molecular and Cellular Biochemistry. 2023 Jul 1
• 8 citations
  Protein kinase CK2 - diverse roles in cancer cell biology and therapeutic promise.
  Janeen H Trembley, Betsy T Kren, Muhammad Afzal, George A Scaria, Mark A Klein, Khalil Ahmed> ;Molecular and Cellular Biochemistry. 2023 Apr 1
• 3 citations
  Biomarkers and the microbiome in the detection and treatment of early-stage non-small cell lung cancer.
  Mark Klein, Alexa A Pragman, Christine Wendt> ;Seminars in Oncology. 2022 Jul 19
• 25 citations
  Sirt6 regulates lifespan in.
  Jackson R Taylor, Jason G Wood, Evan Mizerak, Samuel Hinthorn, Julianna Liu, Matthew Finn, Sarah Gordon, Louis Zingas, Chengyi Chang, Mark A Klein, John M Denu, Vera G...> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Feb 1
• 12 citations
  DARPP-32 promotes ERBB3-mediated resistance to molecular targeted therapy in EGFR-mutated lung adenocarcinoma.
  Sk Kayum Alam, Yongchang Zhang, Li Wang, Zhu Zhu, Christina E. Hernandez, Yuling Zhou, Nong Yang, Jian Lei, Xiaoyan Chen, Liang Zeng, Mark A. Klein, Luke H. Hoeppner> ;Oncogene. 2021 Oct 21
• 8 citations
  Cx-4945 and sirna-mediated knockdown of ck2 improves cisplatin response in hpv(+) and hpv(-) hnscc cell lines
  Janeen H. Trembley, Bin Li, Betsy J Kren, Amy Gravely, Emiro Caicedo-Granados, Mark A. Klein, Khalil Ahmed> ;Biomedicines. 2021 May 18
• 3 citations
  Use of Comprehensive Geriatric Assessment in Oncology Patients to Guide Treatment Decisions and Predict Chemotherapy Toxicity
  Gobind Tarchand, Vicki A. Morrison, Mark A. Klein, Elyse Watkins> ;Federal Practitioner. 2021 May 1
• 1 citations
  Identification of high protein kinase CK2α in HPV(+) oropharyngeal squamous cell carcinoma and correlation with clinical outcomes.
  Janeen H Trembley, Bin Li, Betsy T Kren, Justin Peltola, Juan Manivel, Devi Meyyappan, Amy Gravely, Mark Klein, Khalil Ahmed, Emiro Caicedo-Granados> ;Peerj. 2021 Jan 1
• 21 citations
  Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6.
  Wallace H. Liu, Jie Zheng, Jessica L. Feldman, Mark A. Klein, Vyacheslav I. Kuznetsov, Craig L. Peterson, Patrick R. Griffin, John M. Denu> ;Nature Communications. 2020 Oct 16
• 33 citations
  Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators.
  Mark A. Klein, John M. Denu> ;The Journal of Biological Chemistry. 2020 Aug 7
• 1 citations
  Cyclin-Dependent Kinase and Antioxidant Gene Expression in Cancers with Poor Therapeutic Response.
  George S. Scaria, Betsy T. Kren, Mark A. Klein> ;Pharmaceuticals. 2020 Feb 5
• 31 citations
  Mechanism of activation for the sirtuin 6 protein deacylase
  Mark A. Klein, Can Liu, Vyacheslav I. Kuznetsov, John B. Feltenberger, Weiping Tang, John M. Denu> ;The Journal of Biological Chemistry. 2020 Jan 31
• 6 citations
  Cyclin-dependent kinase inhibition: an opportunity to target protein-protein interactions
  Mark A. Klein> ;Advances in Protein Chemistry and Structural Biology. 2020 Jan 1
• 3 citations
  Use of Mobile Messaging System for Self-Management of Chemotherapy Symptoms in Patients with Advanced Cancer
  Connie Jaenicke, Dan Greenwood, Kathleen Nelson, Mark A. Klein, Bev Foss, Lara Carson, Kim Smith, Evan Mariash> ;Federal Practitioner. 2019 Aug 1
• 3 citations
  Utilization of the Veterans Affairs Central Cancer Registry to evaluate lung cancer outcomes.
  Mark A. Klein, George S. Scaria, Apar Kishor Ganti> ;Seminars in Oncology. 2019 Aug 1
• 28 citations
  An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality
  Christina M. Ferrer, Marielle Alders, Alex V. Postma, Seonmi Park, Mark A. Klein, Murat Cetinbas, Eva Pajkrt, Astrid Glas, Silvana van Koningsbruggen, Vincent M. Chris...> ;Genes & Development. 2018 Mar 19
• 2 citations
  Incidence of unprovoked venous thromboembolic events in patients with chronic lymphocytic leukemia.
  Lauren Katkish, Sravanti Rangaraju, Thomas S. Rector, Amy Gravely, Gerhard J. Johnson, Mark A. Klein, Pankaj Gupta> ;Leukemia & Lymphoma. 2018 Feb 1
• 3 citations
  Impact of educational intervention on management of periprocedural anticoagulation.
  Amy L. Awker, Melissa A. Bell, Megan McGraw, Mark A. Klein> ;American Journal of Health-System Pharmacy. 2017 Dec 1
• 34 citations
  Stabilized helical peptides: overview of the technologies and its impact on drug discovery.
  Mark A. Klein> ;Expert Opinion on Drug Discovery. 2017 Sep 9
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