MarkScottMarshallMD

PubMed

• 33 citations
  Integration of genomic copy number variations and chemotherapy-response biomarkers in pediatric sarcoma
  Lijun Cheng, Pankita H. Pandya, Enze Liu, Pooja Chandra, Limei Wang, Mary E. Murray, Jacquelyn Carter, Michael J. Ferguson, Mohammad Reza Saadatzadeh, Khadijeh Bijangi...> ;BMC Medical Genomics. 2019 Jan 31
• 17 citations
  LY2603618, a selective CHK1 inhibitor, enhances the anti-tumor effect of gemcitabine in xenograft tumor models
  Darlene S. Barnard, H. Bruce Diaz, Teresa F. Burke, Gregory P. Donoho, Richard P. Beckmann, Bonita D. Jones, David Anthony Barda, Constance King, Mark S. Marshall> ;Investigational New Drugs. 2016 Feb 1
• Whole exome sequencing is an efficient, sensitive and specific method for determining the genetic cause of short-rib thoracic dystrophies.
  McInerney-Leo AM, Harris JE, Leo PJ, Marshall MS, Gardiner B, Kinning E, Leong HY, McKenzie F, Ong WP, Vodopiutz J, Wicking C, Brown MA, Zankl A, Duncan EL> ;Clin. Genet.. 2015-12-01
• 126 citations
  LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms.
  Constance King, H. Bruce Diaz, Samuel McNeely, Darlene S. Barnard, Jack A. Dempsey, Wayne Blosser, Richard P. Beckmann, David Anthony Barda, Mark S. Marshall> ;Molecular Cancer Therapeutics. 2015 Sep 1
• 44 citations
  Preclinical analyses and phase I evaluation of LY2603618 administered in combination with pemetrexed and cisplatin in patients with advanced cancer.
  Emiliano Calvo, Victor J. Chen, Mark S. Marshall, Ute Ohnmacht, Scott M. Hynes, Elizabeth Kumm, H. Bruce Diaz, Darlene S. Barnard, Farhana F. Merzoug, Lysiane Huber, L...> ;Investigational New Drugs. 2014 Jun 20
• 79 citations
  Characterization and preclinical development of LY2603618: a selective and potent Chk1 inhibitor
  Constance King, Henry Bruce Diaz, Darlene S. Barnard, David Anthony Barda, David K. Clawson, Wayne Blosser, Karen Cox, Sherry Guo, Mark S. Marshall> ;Investigational New Drugs. 2014 Apr 1
• 96 citations
  Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-κB pathway in pancreatic carcinoma cells
  Michele T. Yip-Schneider, Harikrishna Nakshatri, Christopher Sweeney, Mark S. Marshall, Eric A. Wiebke, C. Max Schmidt> ;Molecular Cancer Therapeutics. 2005 Apr 1
• 217 citations
  PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation
  Jill K. Slack-Davis, Scott T. Eblen, Maja Zecevic, Scott A. Boerner, Adel Tarcsafalvi, H. Bruce Diaz, Mark S. Marshall, Michael J. Weber, J. Thomas Parsons, Andrew D. ...> ;The Journal of Cell Biology. 2003 Jul 21
• Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein.
  Corbit KC, Trakul N, Eves EM, Diaz B, Marshall M, Rosner MR> ;J. Biol. Chem.. 2003-04-11
• 15 citations
  Cyclo-oxygenase-2 expression in primary cancers of the lung and bladder compared to normal adjacent tissue
  Christopher Sweeney, Mark S. Marshall, Darlene S. Barnard, Douglas K. Heilman, Steven D. Billings, Liang Cheng, Steven J. Marshall, Michele T. Yip-Schneider> ;Cancer Detection and Prevention. 2002 Aug 1
• 30 citations
  Transformation of interleukin-3–dependent cells without participation of Stat5/bcl-xL: cooperation of akt with raf/erk leads to p65 nuclear factor κB–mediated antiapop...
  Vasily M. Gelfanov, Burgess Gs, Litz-Jackson S, Alastair J. King, Mark S. Marshall, Harikrishna Nakshatri, H. Scott Boswell> ;Blood. 2001 Oct 15
• 83 citations
  Cell Cycle Effects of Nonsteroidal Anti-Inflammatory Drugs and Enhanced Growth Inhibition in Combination with Gemcitabine in Pancreatic Carcinoma Cells
  Michele T. Yip-Schneider, Christopher Sweeney, Sin-Ho Jung, Pamela L. Crowell, Mark S. Marshall> ;The Journal of Pharmacology and Experimental Therapeutics. 2001 Sep 1
• 105 citations
  Hyperactivation of P21ras and the Hematopoietic-Specific Rho Gtpase, Rac2, Cooperate to Alter the Proliferation of Neurofibromin-Deficient Mast Cells in Vivo and in Vitro
  David A. Ingram, Kelly Hiatt, Alastair J. King, Lucy Fisher, Rama Shivakumar, Christina Derstine, Mary Jo Wenning, Bruce Diaz, Jeffrey B. Travers, Antoinette F. Hood, ...> ;The Journal of Experimental Medicine. 2001 Jul 2
• 35 citations
  Phosphorylation site specificity of the Pak-mediated regulation of Raf-1 and cooperativity with Src
  Alastair J. King, Randall Wireman, Mark Hamilton, Mark S. Marshall> ;FEBS Letters. 2001 May 18
• 67 citations
  Pancreatic Tumor Cells with Mutant K-ras Suppress ERK Activity by MEK-Dependent Induction of MAP Kinase Phosphatase-2
  Michele T. Yip-Schneider, Amy Lin, Mark S. Marshall> ;Biochemical and Biophysical Research Communications. 2001 Feb 2
• 74 citations
  Regulation of the Raf-1 kinase domain by phosphorylation and 14-3-3 association
  Michele T. Yip-Schneider, Wenyan Miao, Amy Lin, Darlene S. Barnard, Guri Tzivion, Mark S. Marshall> ;The Biochemical Journal. 2000 Oct 1
• 139 citations
  Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells.
  Feng Chun Yang, Reuben Kapur, Alastair J. King, Wen Tao, Chaekyun Kim, Jovencio Borneo, Robert Breese, Mark S. Marshall, Mary C. Dinauer, David R. Williams> ;Immunity. 2000 May 1
• 185 citations
  Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338.
  Anu Chaudhary, W. G. King, M. D. Mattaliano, Jeffrey A. Frost, B. Diaz, Deborah K. Morrison, Melanie H. Cobb, Mark S. Marshall, Joan S. Brugge> ;Current Biology. 2000 May 1
• 184 citations
  Molecular Mechanism for the Shp-2 Tyrosine Phosphatase Function in Promoting Growth Factor Stimulation of Erk Activity
  Zhong-Qing Shi, De-Hua Yu, Morag Park, Mark S. Marshall, Gen-Sheng Feng> ;Molecular and Cellular Biology. 2000 Mar 1
• 113 citations
  Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak
  Huaiyu Sun, Alastair J. King, H. Bruce Diaz, Mark S. Marshall> ;Current Biology. 2000 Mar 1
• 248 citations
  Cyclooxygenase-2 expression in human pancreatic adenocarcinomas
  Michele T. Yip-Schneider, Darlene S. Barnard, Steven D. Billings, Liang Cheng, Douglas K. Heilman, Amy Lin, Steven J. Marshall, Pamela L. Crowell, Mark S. Marshall, Ch...> ;Carcinogenesis. 2000 Feb 1
• 62 citations
  Lack of elevated MAP kinase (Erk) activity in pancreatic carcinomas despite oncogenic K-ras expression.
  Michele T. Yip-Schneider, Amy Lin, D Barnard, Christopher Sweeney, Mark S. Marshall> ;International Journal of Oncology. 1999 Aug 1
• 360 citations
  The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338
  Alastair J. King, Huaiyu Sun, Bruce Diaz, Darlene Barnard, Wenyan Miao, Shubha Bagrodia, Mark S. Marshall> ;Nature. 1998 Nov 12
• 67 citations
  Oncogenes, growth factors and phorbol esters regulate Raf-1 through common mechanisms
  Darlene Barnard, Bruce Diaz, David Clawson, Mark S. Marshall> ;Oncogene. 1998 Sep 24
• 28 citations
  In VitroInhibition of Ras–Raf Association by Short Peptides
  Darlene Barnard, Huaiyu Sun, Leroy Baker, Mark S. Marshall> ;Biochemical and Biophysical Research Communications. 1998 Jun 9
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