MaryRachelLeeMD

PubMed

• Alcohol Use Disorder and Posttraumatic Stress Disorder: A Relationship Unbonded by Oxytocin Blockade.
  Leandro F Vendruscolo, Mary R Lee, Lorenzo Leggio> ;Biological Psychiatry. 2023 Aug 1
• 2 citations
  Corticotropin-Releasing Factor receptor 1 (CRF1) antagonism in patients with alcohol use disorder and high anxiety levels: effect on neural response during Trier Socia...
  Mary R Lee, Daniel Rio, Laura Kwako, David T George, Markus Heilig, Reza Momenan> ;Neuropsychopharmacology. 2023 Apr 1
• 33 citations
  Advances in human oxytocin measurement: challenges and proposed solutions.
  Benjamin A Tabak, Gareth Leng, Angela Szeto, Karen J Parker, Joseph G Verbalis, Toni E Ziegler, Mary R Lee, Inga D Neumann, Armando J Mendez> ;Molecular Psychiatry. 2023 Jan 1
• 7 citations
  Gut microbiome and metabolome in a non-human primate model of chronic excessive alcohol drinking.
  Daria Piacentino, Silvia Grant-Beurmann, Carlotta Vizioli, Xiaobai Li, Catherine F. Moore, Victor Ruiz-Rodado, Mary R. Lee, Paule V. Joseph, Claire M. Fraser, Elise M....> ;Translational Psychiatry. 2021 Dec 1
• 3 citations
  Understanding identification-based trust in the light of affiliative bonding: Meta-analytic neuroimaging evidence
  Yan Wu, Apoorva Veerareddy, Mary R. Lee, Gabriele Bellucci, Julia A. Camilleri, Simon B. Eickhoff, Frank Krueger> ;Neuroscience and Biobehavioral Reviews. 2021 Dec 1
• 17 citations
  Nasal oxytocin for the treatment of psychiatric disorders and pain: achieving meaningful brain concentrations.
  David C. Yeomans, Leah R. Hanson, Dean S. Carson, Brendan J. Tunstall, Mary R. Lee, Alexander Tzabazis, Daniel I. Jacobs, William H. Frey> ;Translational Psychiatry. 2021 Jul 10
• 6 citations
  Effect of oral alcohol administration on plasma cytokine concentrations in heavy drinking individuals.
  Mary R. Lee, Kelly M. Abshire, Mehdi Farokhnia, Fatemeh Akhlaghi, Lorenzo Leggio> ;Drug and Alcohol Dependence. 2021 May 21
• 14 citations
  A closer look at alcohol-induced changes in the ghrelin system: novel insights from preclinical and clinical data.
  Sara L. Deschaine, Mehdi Farokhnia, Adriana Gregory-Flores, Lia J. Zallar, Zhi-Bing You, Hui Sun, Deon M. Harvey, Renata C. N. Marchette, Brendan J. Tunstall, Bharath ...> ;Addiction Biology. 2021 Apr 27
• 7 citations
  A Population Pharmacokinetic Analysis of PF-5190457, a Novel Ghrelin Receptor Inverse Agonist in Healthy Volunteers and in Heavy Alcohol Drinkers
  Enoch Cobbina, Mary R. Lee, Lorenzo Leggio, Fatemeh Akhlaghi> ;Clinical Pharmacokinetics. 2021 Apr 1
• 10 citations
  Neuroendocrine Response to Exogenous Ghrelin Administration, Combined With Alcohol, in Heavy-Drinking Individuals: Findings From a Randomized, Double-Blind, Placebo-Co...
  Mehdi Farokhnia, Kelly M. Abshire, Aaron Hammer, Sara L. Deschaine, Anitha Saravanakumar, Enoch Cobbina, Zhi-Bing You, Carolina L. Haass-Koffler, Mary R. Lee, Fatemeh ...> ;The International Journal of Neuropsychopharmacology. 2021 Jul 14
• 18 citations
  A deeper insight into how GABA-B receptor agonism via baclofen may affect alcohol seeking and consumption: lessons learned from a human laboratory investigation.
  Mehdi Farokhnia, Sara L. Deschaine, Armin Sadighi, Lisa A. Farinelli, Mary R. Lee, Fatemeh Akhlaghi, Lorenzo Leggio> ;Molecular Psychiatry. 2021 Feb 1
• 5 citations
  Brief Report: Relationship Between Cotinine Levels and Peripheral Endogenous Concentrations of Oxytocin, β-Endorphin, and Orexin in Individuals With Both Alcohol and N...
  Carolina L. Haass-Koffler, Roberta Perciballi, Zoe E. Brown, Mary R. Lee, William H. Zywiak, Jonathan D. Kurtis, Robert M. Swift, Lorenzo Leggio> ;The American Journal on Addictions. 2021 Jan 1
• 10 citations
  Differences in Sociodemographic and Alcohol-Related Clinical Characteristics Between Treatment Seekers and Nontreatment Seekers and Their Role in Predicting Outcomes i...
  Carolina L. Haass-Koffler, Daria Piacentino, Xiaobai Li, Victoria M. Long, Mary R. Lee, Robert M. Swift, George A. Kenna, Lorenzo Leggio> ;Alcoholism, Clinical and Experimental Research. 2020 Sep 30
• 36 citations
  Oxytocin and the Neurobiology of Prosocial Behavior.
  Nina Marsh, Abigail A. Marsh, Mary R. Lee, René Hurlemann> ;The Neuroscientist. 2020 Sep 26
• 5 citations
  Investigating the link between serum concentrations of brain-derived neurotrophic factor and behavioral measures in anxious alcohol-dependent individuals.
  Jeanelle Portelli, Mehdi Farokhnia, Sara L. Deschaine, Jillian T. Battista, Mary R. Lee, Xiaobai Li, Dorit Ron, Lorenzo Leggio> ;Alcohol. 2020 Aug 13
• 10 citations
  Effects of exogenous ghrelin administration and ghrelin receptor blockade, in combination with alcohol, on peripheral inflammatory markers in heavy-drinking individual...
  Mehdi Farokhnia, Jeanelle Portelli, Mary R. Lee, Gray R. McDiarmid, Kelly M. Abshire, Jillian T. Battista, Brittney D. Browning, Sara L. Deschaine, Fatemeh Akhlaghi, L...> ;Brain Research. 2020 Aug 1
• 19 citations
  Endocrine effects of the novel ghrelin receptor inverse agonist PF-5190457: Results from a placebo-controlled human laboratory alcohol co-administration study in heavy...
  Mary R. Lee, Mehdi Farokhnia, Enoch Cobbina, Anitha Saravanakumar, Xiaobai Li, Jillian T. Battista, Lisa A. Farinelli, Fatemeh Akhlaghi, Lorenzo Leggio> ;Neuropharmacology. 2020 Jun 15
• 75 citations
  Labeled oxytocin administered via the intranasal route reaches the brain in rhesus macaques.
  Mary R. Lee, Tatiana A. Shnitko, Steven W. Blue, A. V. Kaucher, A. J. Winchell, David W. Erikson, Kathleen A. Grant, Lorenzo Leggio> ;Nature Communications. 2020 Jun 3
• 6 citations
  Repetitive Transcranial Magnetic Stimulation Delivered With an H-Coil to the Right Insula Reduces Functional Connectivity Between Insula and Medial Prefrontal Cortex
  Mary R. Lee, Elisabeth C. Caparelli, Michelle K. Leff, Vaughn R. Steele, Andrea M. Maxwell, Karen McCullough, Betty Jo Salmeron> ;Neuromodulation. 2020 Apr 1
• 3 citations
  Regulatory Peptides and Systems Biology: A New Era of Translational and Reverse‐translational Neuroendocrinology
  Lee E. Eiden, Andrew L. Gundlach, Valery Grinevich, Mary R. Lee, André S. Mecawi, Duan Chen, Ruud M. Buijs, Vito S. Hernández, Germán Fajardo-Dolci, Li-Mei Zhang> ;Journal of Neuroendocrinology. 2020 Mar 14
• 2 citations
  A role for the CD38 rs3796863 polymorphism in alcohol and monetary reward: evidence from CD38 knockout mice and alcohol self-administration, [11C]-raclopride binding, ...
  Mary R. Lee, Jung Hoon Shin, Sara L. Deschaine, Allison M. Daurio, Bethany L. Stangl, Jia Yan, Vijay A. Ramchandani, Melanie L. Schwandt, Erica N. Grodin, Reza Momenan...> ;The American Journal of Drug and Alcohol Abuse. 2020 Mar 3
• 9 citations
  Effect of systemically administered oxytocin on dose response for methylphenidate self-administration and mesolimbic dopamine levels.
  Mary R. Lee, Matthew C.H. Rohn, Claudio Zanettini, Mark A. Coggiano, Lorenzo Leggio, Gianluigi Tanda> ;Annals of the New York Academy of Sciences. 2019 Nov 1
• 16 citations
  Using Machine Learning to Classify Individuals With Alcohol Use Disorder Based on Treatment Seeking Status.
  Mary R. Lee, Vignesh Sankar, Aaron Hammer, William G. Kennedy, Jennifer J. Barb, Philip G. McQueen, Lorenzo Leggio> ;Eclinicalmedicine. 2019 Jun 17
• 18 citations
  Compulsivity in Alcohol Use Disorder and Obsessive Compulsive Disorder: Implications for Neuromodulation.
  Elisabetta Burchi, Nikolaos Makris, Mary R. Lee, Stefano Pallanti, Eric Hollander> ;Frontiers in Behavioral Neuroscience. 2019 Apr 11
• 65 citations
  Ghrelin: From a gut hormone to a potential therapeutic target for alcohol use disorder
  Mehdi Farokhnia, Monica L. Faulkner, Daria Piacentino, Mary R. Lee, Lorenzo Leggio> ;Physiology & Behavior. 2019 May 15
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Journal Articles

• A Deeper Insight into How GABA-B Receptor Agonism via Baclofen May Affect Alcohol Seeking and Consumption: Lessons Learned from a Human Laboratory Investigation  
  Mary Lee, MD, Nature
• The Validity of the Montgomery-Asberg Depression Rating Scale in an Inpatient Sample with Alcohol Dependence  
  Hobden B, Schwandt ML, Carey M, Lee MR, Farokhnia M, Bouglal S, Oldmeadow C, Leggio L., Alcoholism: Clinical and Experimental Research, 1/1/2017
• Cognitive behavioral therapy with medication for depressed gay men with AIDS or symptomatic HIV infection  
  Lee MR, Cohen L, Hadley SW, Goodwin, FK., Psychiatry Services, 1/1/1999

Books/Book Chapters

• Integrating Psychological and Pharmacological Treatments for Addictive Disorders: An Evidence-Based Guide 
  Chapter: Stimulant Use Disorders. 
  Page 173.0 - 204.0Daurio A, Lee MR.Editors: J. MacKillop, G.A. Kenna, L. Leggio, L. A. Ray.Routledge (Taylor & Francis Group), New York and London2018
• The Neuroscience of Cocaine: Mechanisms and Treatment 
  Chapter: Oxytocin�s Effects in Cocaine Addiction 
  Page 227.0 - 234.0Lee MR, Rohn MCH, Tanda G, Leggio L.Editors: V. Preedy.2017

Lectures

• Treatment of Alcohol Use Disorder in Patients with Alcoholic Liver Disease 
  1/1/2017
• Targeting the Oxytocin System to Treat Addictive Disorders: Rational and Progress to Date. 
  1/1/2016
• Oxytocin for the treatment of drug and alcohol use disorders 
  1/1/2016
• Management of alcohol use disorder in patients requiring liver transplant 
  1/1/2015
• Adjunctive intranasal oxytocin to improve social cognition and functioning in schizophrenia 
  Florence, Italy - 1/1/2012
• Neuroimaging approaches to the development of treatment for substance use disorders 
  San Francisco, CA - 1/12/2011
• Oxytocin and Cocaine Dependence 
  1/27/2015
• Role of Oxytocin in Addiction: Beyond �Love Story� 
  San Antonio, TX, - 1/24/2015
• Importance of Oxytocin and Dopamine in Addiction: a Translational Approach 
  San Antonio, TX, - 1/24/2015
• Beyond Social Bonding: The Role of Oxytocin in Drug Abuse and Addiction 
  National Institute on Drug Abuse - 1/26/2015
• How fast should we stimulate: measuring the effect of deep rTMS on task-based and resting state functional connectivity 
  Geneva, Switzerland - 1/24/2016
• Oxytocin and Addictions: Beyond Love Story? 
  Hollywood, FL - 1/4./2016
• Oxytocin Promotes Resilience to Substance Use Disorder vulnerability 
  Big Sky Montana - 1/28/2017
• Translating oxytocin neuroscience to the treatment of mental disorders 
  Berlin, Germany - 1/8./2017
• Oxytocin: A New Approach to Treating Addiction 
  Central Institute of Mental Health, Mannheim, Germany - 1/16/2017
• Oxytocin and Addictions 
  New York, NY - 1/5./2018
• Integrating Alcohol Use Disorder Care in the Management of Alcoholic Hepatitis 
  San Diego, CA - 1/16/2018
• Peptide-based drug discovery for CNS disorders: Avenues and Barriers 
  Acapulco, Mexico - 1/22/2018
• Peripheral activities in the oxytocin and vasopressin systems 
  Ein Gedi resort, Israel - 1/7./2019
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