MatthewHLevineMD

General Surgery • Philadelphia, PA

Hepatobiliary Surgery, Pancreas, Transplantation

Assistant Professor, Surgery, Perelman School of Medicine

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Office
3400 Spruce Street
1 Founders
Philadelphia, PA 19104
Phone+1 215-662-7367

Fax+1 215-615-4900
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Education & Training

University of California (San Francisco)Fellowship, Abdominal Transplant Surgery, 2007 - 2008
Massachusetts General HospitalResidency, Surgery, 2001 - 2006
Yale UniversityPhD, Immunobiology, 1994 - 2001
Yale School of MedicineClass of 2001
Brown UniversityScB, Biochemistry, 1990 - 1994

Certifications & Licensure

CA State Medical License 2006 - Present
PA State Medical License 2008 - 2024
MA State Medical License 2006 - 2006
American Board of Surgery Surgery
American Society of Transplant SurgeonsAbdominal Transplant Certification (Liver, Kidney, Pancreas)

Awards, Honors, & Recognition

Surgical Co-Director CHOP Pediatric Transplant Center CHOP
Fellow (FACS) American College of Surgeons

Clinical Trials

Intravenous Estrogen in Kidney Transplant Study Start of enrollment: 2016 Aug 26
Active, not recruiting
Phase 1, Phase 2

Publications & Presentations

PubMed

Longer-Term Clinical Outcomes From the THINKER and EXPANDER Trials of Transplantation of HCV-RNA+ Donor Kidneys Into Hepatitis C Virus-Negative Recipients.
Vishnu Potluri, Fizza Naqvi, David S Goldberg, Mital Shah, Alexandre Loupy, Peter Abt, Emily Blumberg, Jennifer Trofe-Clark, Roy Bloom, Deirdre Sawinski, Michael Chatt...> ;Kidney International Reports. 2023 Jul 1
1 citations
Incidence of acute rejection and patient survival in combined heart-liver transplantation.
Kai Zhao, Roy Wang, Malek Kamoun, Lauren Callans, Remy Bremner, Eduardo Rame, Rhondalyn McLean, Marisa Cevasco, Kim M Olthoff, Matthew H Levine, Abraham Shaked, Peter ...> ;Liver Transplantation. 2022 Sep 1
2 citations
The Selective Estrogen Receptor Modulator, Raloxifene, Is Protective Against Renal Ischemia-reperfusion Injury.
Paul Hernandez, Ciaran O'Brien, Seth J Concors, Zhonglin Wang, Guanghui Ge, Wayne W Hancock, Matthew H Levine> ;Transplantation. 2022 Nov 1
17 citations
Kynurenine induces T cell fat catabolism and has limited suppressive effects in vivo.
Peter J Siska, Jing Jiao, Carina Matos, Katrin Singer, Raffaela S Berger, Katja Dettmer, Peter J Oefner, Michelle D Cully, Zhonglin Wang, William J QuinnIII, Kristen N...> ;Ebiomedicine. 2021 Dec 1
7 citations
Obesity-related IL-18 Impairs T-Regulatory Cell Function and Promotes Lung Ischemia-Reperfusion Injury.
Tatiana Akimova, Tianyi Zhang, Lanette M Christensen, Zhonglin Wang, Rongxiang Han, Dmitry Negorev, Arabinda Samanta, Isaac E Sasson, Trivikram Gaddapara, Jing Jiao, L...> ;American Journal of Respiratory and Critical Care Medicine. 2021 Nov 1
406 citations
Hepatobiliary cancers, Version 2.2021
Al B. Benson, Michael I. D’Angelica, Daniel E. Abbott, Daniel A. Anaya, Robert A. Anders, Chandrakanth Are, Melinda Bachini, Mitesh J. Borad, Daniel B. Brown, Adam M. ...> ;Journal of the National Comprehensive Cancer Network. 2021 May 1
10 citations
HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury.
David D. Aufhauser, Paul T. Hernandez, Seth J. Concors, Ciaran O’Brien, Zhonglin Wang, Douglas R. Murken, Arabinda Samanta, Ulf H. Beier, Lauren N. Krumeich, Tricia R....> ;Scientific Reports. 2021 Apr 27
4 citations
Occult Hepatocellular Carcinoma Associated with Transjugular Intrahepatic Portosystemic Shunts in Liver Transplant Recipients
Lauren N. Krumeich, Jenna Mancinelli, Andy Cucchiara, Kevin C. Eddinger, David D. Aufhauser, Drew W Goldberg, Evan S. Siegelman, K. Rajender Reddy, Maarouf Hoteit, Emm...> ;Liver Transplantation. 2021 Sep 1
Successful transatlantic bilateral hand transplant in a young female highly sensitized to HLA class II antigens.
Saïd C. Azoury, F. Bradley Johnson, Matthew H. Levine, Stephanie Veasey, Christine McAndrew, Abraham Shaked, Laurent Lantieri, Malek Kamoun, L. Scott Levin> ;Transplant Immunology. 2021 Apr 1
120 citations
Lactate Limits T Cell Proliferation via the NAD(H) Redox State.
William J. Quinn, Jing Jiao, Tara TeSlaa, Jason Stadanlick, Zhonglin Wang, Liqing Wang, Tatiana Akimova, Alessia Angelin, Patrick M. Schäfer, Michelle D. Cully, Caroli...> ;Cell Reports. 2020 Dec 15
57 citations
Liver Transplantation Outcomes in a U.S. Multicenter Cohort of 789 Patients With Hepatocellular Carcinoma Presenting Beyond Milan Criteria
Ani Kardashian, Sander Florman, Brandy Haydel, Richard Ruiz, Goran B. Klintmalm, David D. Lee, C. Burcin Taner, Federico Aucejo, Amit D. Tevar, Abhinav Humar, Elizabet...> ;Hepatology. 2020 Dec 1
5 citations
Acute Kidney Injury in Deceased Organ Donors and Kidney Transplant Outcomes: A National Cohort Study using a Novel Data Source.
Elizabeth M. Sonnenberg, Jesse Y. Hsu, Jordana B. Cohen, Vishnu S. Potluri, Zhi Geng, Matthew H. Levine, Peter L. Abt, Peter P. Reese> ;Annals of Surgery. 2020 Nov 13
Response to letters concerning: "Kidney transplantation and donation in the transgender population: A single-institution case series".
Omar I Ramadan, Ali Naji, Matthew H. Levine, Paige M. Porrett, Ty B. Dunn, Mary Kaminski, Jennifer Trofe-Clark, Ilona Lorincz, Emily A. Blumberg, Blair C. Weikert, Mel...> ;American Journal of Transplantation. 2020 Jul 22
22 citations
Counter Regulation of Spic by NF-κB and STAT Signaling Controls Inflammation and Iron Metabolism in Macrophages.
Zahidul Alam, Samir Devalaraja, Minghong Li, Tsun Ki Jerrick To, Ian W. Folkert, Erick Mitchell-Velasquez, Mai Tu Dang, Patricia Young, Christopher J. Wilbur, Michael ...> ;Cell Reports. 2020 Jun 30
5 citations
Donor bone-marrow CXCR4+ Foxp3+ T-regulatory cells are essential for costimulation blockade-induced long-term survival of murine limb transplants.
Liqing Wang, Zhonglin Wang, Rongxiang Han, Arabinda Samanta, Guanghui Ge, L. Scott Levin, Matthew H. Levine, Wayne W. Hancock> ;Scientific Reports. 2020 Jun 9
6 citations
Tissue metabolic profiling shows that saccharopine accumulates during renal ischemic-reperfusion injury, while kynurenine and itaconate accumulate in renal allograft r...
Ulf H. Beier, Erum A. Hartung, Seth J. Concors, Paul T. Hernandez, Zhonglin Wang, Caroline Perry, Joseph A. Baur, Michelle R. Denburg, Wayne W. Hancock, Terence P. Gad...> ;Metabolomics. 2020 May 4
11 citations
Kidney transplantation and donation in the transgender population: A single-institution case series.
Omar I Ramadan, Ali Naji, Matthew H. Levine, Paige M. Porrett, Ty B. Dunn, Susanna M. Nazarian, Mary Kaminski, David Johnson, Jennifer Trofe-Clark, Ilona Lorincz, Emil...> ;American Journal of Transplantation. 2020 Apr 30
57 citations
Pathologic Response to Pretransplant Locoregional Therapy is Predictive of Patient Outcome After Liver Transplantation for Hepatocellular Carcinoma: Analysis From the ...
Joseph DiNorcia, Sander Florman, Brandy Haydel, Parissa Tabrizian, Richard Ruiz, Goran B. Klintmalm, Srinath Senguttuvan, David D. Lee, C. Burcin Taner, Elizabeth C. V...> ;Annals of Surgery. 2020 Apr 1
19 citations
The impact of belatacept on third-party HLA alloantibodies in highly sensitized kidney transplant recipients.
Ronald F. Parsons, Arslan Zahid, Shalini Bumb, Hannah Decker, Harold C. Sullivan, Frances Eun-Hyung Lee, Idelberto R. Badell, Mandy L. Ford, Christian P. Larsen, Thoma...> ;American Journal of Transplantation. 2020 Feb 1
30 citations
Peritransplant eculizumab does not prevent delayed graft function in deceased donor kidney transplant recipients: Results of two randomized controlled pilot trials
Bernd Schröppel, Enver Akalin, Mukta Baweja, Roy D. Bloom, Sander Florman, Michael J. Goldstein, Brandy Haydel, Donald E. Hricik, Sanjay Kulkarni, Matthew H. Levine, A...> ;American Journal of Transplantation. 2020 Feb 1
80 citations
Transplanting hepatitis C virus-infected hearts into uninfected recipients: A single-arm trial.
Rhondalyn C. McLean, Peter P. Reese, Michael A. Acker, Pavan Atluri, Christian A. Bermudez, Lee R. Goldberg, Peter L. Abt, Emily A. Blumberg, Vivianna M. Van Deerlin, ...> ;American Journal of Transplantation. 2019 Sep 1
2 citations
Application of Prescription Drug Monitoring Program to detect underreported controlled substance use in patients evaluated for liver transplant.
Samantha Halpern, David O. Walls, Anuranita Gupta, Alexa Lustig, Matthew H. Levine, Peter L. Abt> ;American Journal of Transplantation. 2019 Aug 22
3 citations
Use of public health service increased risk kidneys in pediatric renal transplant recipients
Melissa R Meyers, Justine Shults, Benjamin L. Laskin, Paige M. Porrett, Matthew H. Levine, Peter L. Abt, Sandra Amaral, David S. Goldberg> ;Pediatric Transplantation. 2019 Aug 1
4 citations
Class and Kinetics of Weakly Reactive Pretransplant Donor-specific HLA Antibodies Predict Rejection in Kidney Transplant Recipients.
Alexander H. Morrison, Meera Gupta, Kelsey Lloyd, Jennifer Trofe-Clark, Mary Ann Lim, Christine Limonte, Matthew H. Levine, Deirdre Sawinski, Malek Kamoun, Paige M. Po...> ;Transplantation Direct. 2019 Jul 25
16 citations
An Advanced Practice Practitioner-Based Program to Reduce 30- and 90-Day Readmissions After Liver Transplantation.
Nadim Mahmud, Samantha Halpern, Rebecca Farrell, Kate Ventura, Arwin Thomasson, Heidi Lewis, Kim M. Olthoff, Matthew H. Levine, Susanna M. Nazarian, Vandana Khungar> ;Liver Transplantation. 2019 Jun 1
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Journal Articles

Twelve-Month Outcomes After Transplant of Hepatitis C–infected Kidneys into Uninfected Recipients: A Single-Group Trial
David S Goldberg, Roy D Bloom, Vishnu S Potluri, Susanna M Nazarian, Ali Naji, Emily A Blumberg, Peter L Abt, Peter P Reese, Matthew Levine, Paige Porrett, Melissa Ble..., Annals of Internal Medicine