MichaelBrinesMDPhD

PubMed

• 1 citations
  The erythropoietin-derived peptide ARA 284 reduces tissue wasting and improves survival in a rat model of cancer cachexia.
  Sandra Palus, Yulia Elkina, Tanja Braun, Stephan von Haehling, Wolfram Döhner, Stefan D Anker, Anthony Cerami, Michael Brines, Jochen Springer> ;Journal of Cachexia, Sarcopenia and Muscle. 2022 Aug 1
• 2 citations
  Famotidine activates the vagus nerve inflammatory reflex to attenuate cytokine storm.
  Huan Yang, Sam J George, Dane A Thompson, Harold A Silverman, Téa Tsaava, Aisling Tynan, Valentin A Pavlov, Eric H Chang, Ulf Andersson, Michael Brines, Sangeeta S Cha...> ;Molecular Medicine. 2022 May 16
• 12 citations
  Famotidine activates the vagus nerve inflammatory reflex to attenuate cytokine storm.
  Huan Yang, Sam J George, Dane Thompson, Harold A Silverman, Tea Tsaava, Aisling Tynan, Valentin A Pavlov, Eric Chang, Ulf Andersson, Michael Brines, Sangeeta S Chavan,...> ;Research Square. 2022 Apr 11
• Editorial: Erythropoietin and Its Analogues as Therapeutics for Neurological Diseases.
  Michael Brines, Stephana Carelli, Michele Samaja, Edith M Schneider Gasser> ;Frontiers in Pharmacology. 2022 Jan 1
• 1 citations
  The Non-Erythropoietic EPO Analogue Cibinetide Inhibits Osteoclastogenesis In Vitro and Increases Bone Mineral Density in Mice.
  Zamzam Awida, Almog Bachar, Hussam Saed, Anton Gorodov, Nathalie Ben-Califa, Maria Ibrahim, Albert Kolomansky, Jennifer Ana Iden, Liad Graniewitz Visacovsky, Tamar Lir...> ;International Journal of Molecular Sciences. 2021 Dec 21
• 4 citations
  Systemic administration of choline acetyltransferase decreases blood pressure in murine hypertension.
  Andrew Stiegler, Jianhua Li, Vivek Shah, Tea Tsaava, Aisling Tynan, Huan Yang, Yehuda Tamari, Michael Brines, Kevin J. Tracey, Sangeeta S. Chavan> ;Molecular Medicine. 2021 Oct 21
• 13 citations
  Neurons Are a Primary Driver of Inflammation via Release of HMGB1
  Huan Yang, Ulf Andersson, Michael Brines> ;Cells. 2021 Oct 18
• 10 citations
  Control of inflammation using non-invasive neuromodulation: past, present and promise.
  Aisling Tynan, Michael Brines, Sangeeta S. Chavan> ;International Immunology. 2021 Sep 24
• 4 citations
  Cibinetide Protects Isolated Human Islets in a Stressful Environment and Improves Engraftment in the Perspective of Intra Portal Islet Transplantation.
  Ming Yao, Anna Domogatskaya, Nils Ågren, Masaaki Watanabe, Kazuaki Tokodai, Michael Brines, Anthony Cerami, Bo Göran Ericzon, Makiko Kumagai-Braesch, Torbjörn Lundgren> ;Cell Transplantation. 2021 Sep 9
• 32 citations
  HMGB1 released from nociceptors mediates inflammation
  Huan Yang, Qiong Zeng, Harold A. Silverman, Manojkumar Gunasekaran, Sam George, Alex Devarajan, Meghan E. Addorisio, Jianhua Li, Tea Tsaava, Vivek Shah, Timothy R. Bil...> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Aug 17
• 6 citations
  A Phase 2 Clinical Trial on the Use of Cibinetide for the Treatment of Diabetic Macular Edema
  Noemi Lois, Evie Gardner, Margaret McFarland, David J. Armstrong, Christine McNally, Nuala Jane Lavery, Christina Campbell, Rita I Kirk, Daiva Bajorunas, Ann Dunne, An...> ;Journal of Clinical Medicine. 2020 Jul 14
• 63 citations
  Corneal confocal microscopy: ready for prime time
  Ioannis N. Petropoulos, Georgios Ponirakis, Adnan Khan, Hoda Gad, Hamad Almuhannadi, Michael Brines, Anthony Cerami, Rayaz A. Malik> ;Clinical & Experimental Optometry. 2020 May 1
• 4 citations
  Improvement of Islet Allograft Function Using Cibinetide, an Innate Repair Receptor Ligand.
  Ming Yao, Masaaki Watanabe, Sune Sun, Kazuaki Tokodai, Anthony Cerami, Michael Brines, Claes-Göran Östenson, Bo Göran Ericzon, Torbjörn Lundgren, Makiko Kumagai-Braesch> ;Transplantation. 2020 Apr 24
• 79 citations
  Early nerve fibre regeneration in individuals with type 1 diabetes after simultaneous pancreas and kidney transplantation.
  Shazli Azmi, Maria Jeziorska, Maryam Ferdousi, Ioannis N. Petropoulos, Georgios Ponirakis, Andrew Marshall, Uazman Alam, Omar Asghar, Andrew Atkinson, Wendy Jones, And...> ;Diabetologia. 2019 Jun 7
• 15 citations
  The vasoreparative potential of endothelial colony-forming cells in the ischemic retina is enhanced by cibinetide, a non-hematopoietic erythropoietin mimetic
  Olivia E. O'Leary, Paul Canning, Emma Reid, Pietro Maria Bertelli, Stuart McKeown, Michael Brines, Anthony Cerami, Xuan Du, Heping Xu, Mei Chen, Louise R. Dutton, Dere...> ;Experimental Eye Research. 2019 May 1
• 60 citations
  Corneal nerve fiber size adds utility to the diagnosis and assessment of therapeutic response in patients with small fiber neuropathy.
  Michael Brines, Daniel A. Culver, Maryam Ferdousi, Martijn R. Tannemaat, Monique van Velzen, Albert Dahan, Rayaz A. Malik> ;Scientific Reports. 2018 Mar 16
• 8 citations
  Activation of the EPOR-β common receptor complex by cibinetide ameliorates impaired wound healing in mice with genetic diabetes
  Alessandra Bitto, Natasha Irrera, Gabriele Pizzino, Giovanni Pallio, Federica Mannino, Mario Vaccaro, Vincenzo Arcoraci, Federica Aliquò, Letteria Minutoli, Michele R....> ;Biochimica Et Biophysica Acta. Molecular Basis of Disease. 2018 Feb 1
• 8 citations
  Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis
  Manfred Nairz, David Haschka, Stefanie Dichtl, Thomas Sonnweber, Andrea Schroll, Malte Aßhoff, John E. Mindur, Patrizia Moser, Dominik Wolf, Filip K. Swirski, Igor The...> ;Scientific Reports. 2017 Oct 12
• 10 citations
  Quantification of small fiber pathology in patients with sarcoidosis and chronic pain using cornea confocal microscopy and skin biopsies.
  Linda Oudejans, Marieke Niesters, Michael Brines, Albert Dahan, Monique van Velzen> ;Journal of Pain Research. 2017 Aug 26
• 76 citations
  Cibinetide Improves Corneal Nerve Fiber Abundance in Patients With Sarcoidosis-Associated Small Nerve Fiber Loss and Neuropathic Pain
  Daniel A. Culver, Albert Dahan, Daiva Bajorunas, Maria Jeziorska, Monique van Velzen, Leon Aarts, Jinny Tavee, Martijn R. Tannemaat, Ann Dunne, Rita I Kirk, Ioannis N....> ;Investigative Ophthalmology & Visual Science. 2017 May 1
• 21 citations
  ARA290, a Specific Agonist of Erythropoietin/CD131 Heteroreceptor, Improves Circulating Endothelial Progenitors' Angiogenic Potential and Homing Ability
  Guillaume Hache, Philippe Garrigue, Youssef Bennis, Jimmy Stalin, Anaïs Moyon, Anthony Cerami, Michael Brines, Marcel Blot-Chabaud, Florence Sabatier, Françoise Dignat...> ;Shock. 2016 Oct 1
• 9 citations
  Targeting the innate repair receptor to treat neuropathy.
  Albert Dahan, Michael Brines, Marieke Niesters, Anthony Cerami, Monique van Velzen> ;Pain Reports. 2016 Jul 1
• 43 citations
  Cornea nerve fiber quantification and construction of phenotypes in patients with fibromyalgia.
  Linda Oudejans, Xuan He, Marieke Niesters, Albert Dahan, Michael Brines, Monique van Velzen> ;Scientific Reports. 2016 Mar 23
• 18 citations
  A Nonhematopoietic Erythropoietin Analogue, ARA 290, Inhibits Macrophage Activation and Prevents Damage to Transplanted Islets.
  Masaaki Watanabe, Torbjörn Lundgren, Yu Saito, Anthony Cerami, Michael Brines, Claes-Göran Östenson, Makiko Kumagai-Braesch> ;Transplantation. 2016 Mar 1
• 9 citations
  ARA290 Improves Insulin Release and Glucose Tolerance in Type 2 Diabetic Goto-Kakizaki Rats
  Carole Muller, Kamal Yassin, Luo-Sheng Li, Magnus Palmblad, S. Efendic, Per Olof Berggren, Anthony Cerami, Michael Brines, Claes-Göran Östenson> ;Molecular Medicine. 2015 Dec 29
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