Michael Daniel Keller MD

Clinical & Laboratory Immunology

Associate Professor

Summary

Dr. Michael Keller is an Associate Professor at Children's National Hospital in Washington, DC, specializing in Allergy & Immunology with subspecialties in Clinical & Laboratory Immunology. He completed his medical education at Duke University School of Medicine, followed by training in Pediatrics at Johns Hopkins University and fellowship in Allergy and Immunology at Children's Hospital of Philadelphia. Dr. Keller's expertise includes clinical immunology and diseases related to immune dysregulation. He has conducted clinical trials on virus-specific T cells and related cellular therapies. His recent publications are featured in high-impact journals such as Blood Advances and Nature.

Children's Hospital of PhiladelphiaFellowship, Allergy and Immunology, 2010 - 2012
Johns Hopkins UniversityResidency, Pediatrics, 2007 - 2010
Johns Hopkins UniversityInternship, Pediatrics, 2007 - 2008
Duke University School of MedicineClass of 2007
University of VirginiaBS, 1999 - 2002

PubMed

How I Treat: Chronic granulomatous disease.
Jennifer W Leiding, Leah H Pettiford, Christopher C Chang, Aimee M Dassner, Mary C Dinauer
Journal of Human Immunity. 2026-05-04
Third-Party Viral Specific T Cells for Immunocompromised Hosts and Access Barriers: A Review and Commentary by an Expert Panel from ASTCT.
Stella M Davies, Emily Blyth, Catherine M Bollard, John Craddock, Parastoo B Dahi
Transplantation and Cellular Therapy. 2026-05-02
Targeted deep sequencing identifies mosaicism in patients with immune dysregulation.
Elizabeth G Schmitz, Alexander J Paul, Rajarshi Ghosh, Nermina Saucier, Ana Kolicheski
The Journal of Allergy and Clinical Immunology. 2026-05-01

Journal Articles

Adoptive Immunotherapy for Primary Immunodeficiency Disorders with Virus-Specific T-lymphocytes
Naik S, Nicholas SK, Martinez CA, Leen AM, Hanley PJ, Gottschalk SM, Rooney CM, Hanson IC, Krance RA, Shpall EJ, Cruz CR, Amrolia P, Lucchini G, Bunin N, Heimall J, Kl..., J Allergy Clin Immunol
Major histocompatibility complex class II deficiency due to a novel mutation in RFXANK in a child of Mexican descent
Clarridge K, Leitenberg D, Loechelt B, Picard C, Keller MD, Journal of Clinical Immunology, 1/2016
Mutation in IRF2BP2 is responsible for a Familial Form of Common Variable Immunodeficiency Disorder
Keller MD, Pandey R, Li D, Glessner J, Tian L, Henrickson S, Chinn IK, Monaco-Shawver L, Heimall J, Hou C, Otieno FG, Jyonouchi S, Calabrese L, van Montfrans J, Orange..., J Allergy Clin Immunol, 2016

Abstracts/Posters

IRF2BP2 mutation in familial Common Variable Immunodeficiency identified by Support Vector Algorithm and Whole Exome Sequencing.
Keller MD, Tian L, Glessner J, Orange JS, Hakonarson H, Oral presentation, European Society of Immunodeficiency
Severe Combined Immunodeficiency resulting from mutations in MTHFD1.
Keller MD, Ganesh J, Heltzer M, Paessler M, Bergqvist AG, Baluarte HJ, Watkins D, Rosenblatt D, and Orange JS, Oral abstract, Clinical Immunology Society
Incidence of Immunodeficiency in Patients with 49-XXXXY Chromosomal Variation.
Keller MD, Sadeghin T, Samango-Sprouse C, and Orange JS, Poster presentation, AAAAI annual meeting

Michael D. Keller, MD, Named as Inaugural Professor of Precision MedicineJuly 21st, 2025
CellBuilder: A Ready-Made Solution for Cell & Gene Therapy ManufacturingSeptember 11th, 2024
Children’s National Hospital & NIAID Share Early Study Findings on Tailored T-cells for Rare VirusesNovember 19th, 2019