MichaelDanielKellerMD

PubMed

• Mending RAG2: gene editing for treatment of RAG2 deficiency.
  Elizabeth D Hicks, Michael D Keller> ;Blood Advances. 2024 Apr 9
• Secondary bone marrow graft loss after third-party virus-specific T cell infusion: Case report of a rare complication.
  Michael D Keller, Stefan A Schattgen, Shanmuganathan Chandrakasan, E Kaitlynn Allen, Mariah A Jensen-Wachspress, Christopher A Lazarski, Muna Qayed, Haili Lang, Patric...> ;Nature Communications. 2024 Mar 29
• Development of a Safety Surveillance Plan for the Academic Medicine Sponsor Performing First-in-Human Cellular Therapy Clinical Trials: A Report from the Consortium fo...
  Adams, C., Michlitsch, J., Chen, K., Hossain, M., Davis, A., Park, J., Gardner, R., Keller, M., Aguayo-Hiraldo, P., Verneris, M.> ;Transplantation and Cellular Therapy. 2024 Mar 4
• Implementation of a tier system for IVIG indications to address IVIG shortage at a tertiary care pediatric medical center.
  Darwish, C., Hammer, B., Ahmed-Winston, S., Escalante, E., Madrigal, V., Patrick, D., Grant, C., Kahn, I., Roth, K., Keller, M., Diab, Y., Hanisch, B., Khan, S., Moudg...> ;Pediatric Blood & Cancer. 2024 Apr 1
• 9 citations
  Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency.
  Tom Le Voyer, Audrey V Parent, Xian Liu, Axel Cederholm, Adrian Gervais, Jérémie Rosain, Tina Nguyen, Malena Perez Lorenzo, Elze Rackaityte, Darawan Rinchai, Peng Zhan...> ;Nature. 2023 Nov 1
• Myelin oligodendrocyte glycoprotein antibody-associated disease as a novel presentation of central nervous system autoimmunity in a pediatric patient with Wiskott-Aldr...
  Vivien X Xie, Wilson File, Christina Wiedl, Brant R Ward, Blachy Dávila Saldaña, Michael D Keller, Alexandra B Kornbluh> ;Allergy, Asthma, and Clinical Immunology. 2023 Aug 7
• 7 citations
  Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from...
  Thakar, M., Logan, B., Puck, J., Dunn, E., Buckley, R., Cowan, M., O'Reilly, R., Kapoor, N., Satter, L., Pai, S., Heimall, J., Chandra, S., Ebens, C., Chellapandian, D...> ;Lancet. 2023 Jul 8
• Outcomes following posttransplant virus-specific T-cell therapy in patients with sickle cell disease.
  Hannah Kinoshita, Mamatha Mandava, Mariah Jensen-Wachspress, Haili Lang, Elisabeth Joy, Jay Tanna, Chase D McCann, Samuel O'Brien, Sianna Burnett, Abeer Shibli, Fahmid...> ;Blood Advances. 2023 May 23
• 8 citations
  Third-Party and Patient-Specific Donor-Derived Virus-Specific T Cells Demonstrate Similar Efficacy and Safety for Management of Viral Infections after Hematopoietic St...
  Thomas J Galletta, Adam Lane, Carolyn Lutzko, Thomas Leemhuis, Jose A Cancelas, Ruby Khoury, YunZu M Wang, Patrick J Hanley, Michael D Keller, Catherine M Bollard, Ste...> ;Transplantation and Cellular Therapy. 2023 May 1
• 1 citations
  Long-Term Immune Reconstitution in ADA-Deficient Patients Treated With Elapegademase: A Real-World Experience.
  Luis Murguia-Favela, Sneha Suresh, Nicola A M Wright, Saima Alvi, Sarah Tehseen, Vivian Hernandez-Trujillo, Christine M Seroogy, Elie Haddad, Daime Nieves, Michael S H...> ;The Journal of Allergy and Clinical Immunology. in Practice. 2023 Jun 1
• 7 citations
  Applications of virus-specific T cell therapies post-BMT.
  Cecilia M Motta, Michael D Keller, Catherine M Bollard> ;Seminars in Hematology. 2023 Jan 1
• 6 citations
  FOXI3 haploinsufficiency contributes to low T-cell receptor excision circles and T-cell lymphopenia.
  Rajarshi Ghosh, Marita Bosticardo, Sunita Singh, Morgan Similuk, Ottavia M Delmonte, Francesca Pala, Christine Peng, Colleen Jodarski, Michael D Keller, Ivan K Chinn, ...> ;The Journal of Allergy and Clinical Immunology. 2022 Dec 1
• Natural history of infants with non-SCID T cell lymphopenia identified on newborn screen.
  Stephanie A Kubala, Amandeep Sandhu, Thamiris Palacios-Kibler, Brant Ward, Gretchen Harmon, Magee L DeFelice, Vanessa Bundy, M Elizabeth M Younger, Howard Lederman, Hu...> ;Clinical Immunology. 2022 Dec 1
• 2 citations
  A Heterozygous Gain-of-Function Variant in IKBKB Associated with Autoimmunity and Autoinflammation.
  Keith Sacco, Hye Sun Kuehn, Tomoki Kawai, Nouf Alsaati, Lauren Smith, Blachy Davila, Vanessa Bundy, Douglas B Kuhns, Kerry Dobbs, Ottavia Delmonte, Luigi D Notarangelo...> ;Journal of Clinical Immunology. 2023 Feb 1
• 11 citations
  Immunizing the imperfect immune system: Coronavirus disease 2019 vaccination in patients with inborn errors of immunity.
  Jessica R Durkee-Shock, Michael D Keller> ;Annals of Allergy, Asthma & Immunology. 2022 Nov 1
• 10 citations
  Clinical exome sequencing of 1000 families with complex immune phenotypes: Toward comprehensive genomic evaluations.
  Myles, I. A., Morgan N Similuk, Jia Yan, Rajarshi Ghosh, Andrew J Oler, Luis M Franco, Michael R Setzer, Michael Kamen, Colleen Jodarski, Thomas DiMaggio, Joie Davis, ...> ;The Journal of Allergy and Clinical Immunology. 2022 Oct 1
• Robust immune responses to SARS-CoV-2 in a pediatric patient with B-Cell ALL receiving tisagenlecleucel.
  Oren M Gordon, Madeline Terpilowski, Robin Dulman, Michael D Keller, Peter D Burbelo, Jeffrey I Cohen, Catherine M Bollard, Hema Dave> ;Pediatric Hematology and Oncology. 2022 Sep 1
• 12 citations
  Cellular therapies for the treatment and prevention of SARS-CoV-2 infection.
  Susan R Conway, Michael D Keller, Catherine M Bollard> ;Blood. 2022 Jul 21
• 4 citations
  Transcriptomic analysis reveals optimal cytokine combinations for SARS-CoV-2-specific T cell therapy products.
  Jessica Durkee-Shock, Christopher A Lazarski, Mariah A Jensen-Wachspress, Anqing Zhang, Aran Son, Vaishnavi V Kankate, Naomi E Field, Kathleen Webber, Haili Lang, Susa...> ;Molecular Therapy. Methods & Clinical Development. 2022 Jun 9
• 11 citations
  Scheduled administration of virus-specific T cells for viral prophylaxis after pediatric allogeneic stem cell transplant.
  Jeremy D Rubinstein, Carolyn Lutzko, Thomas Leemhuis, Xiang Zhu, Giang Pham, Lorraine Ray, Shawn Thomas, Celeste Dourson, Jamie Wilhelm, Adam Lane, Jose A Cancelas, Da...> ;Blood Advances. 2022 May 10
• Morbidity, Mortality, and Therapeutics in Combined Immunodeficiency: Data From the USIDNET Registry.
  Jessica Durkee-Shock, Anqing Zhang, Hua Liang, Hannah Wright, Julieann Magnusson, Elizabeth Garabedian, Rebecca A Marsh, Kathleen E Sullivan, Michael D Keller> ;The Journal of Allergy and Clinical Immunology. in Practice. 2022 May 1
• 15 citations
  Outcome of donor-derived TAA-T cell therapy in patients with high-risk or relapsed acute leukemia post allogeneic BMT.
  Hannah Kinoshita, Kenneth R Cooke, Melanie Grant, Maja Stanojevic, C Russell Cruz, Michael Keller, Maria Fernanda Fortiz, Fahmida Hoq, Haili Lang, A John Barrett, Hua ...> ;Blood Advances. 2022 Apr 26
• 10 citations
  Off the Shelf Third Party Virus Specific T-Cell Therapy to Treat JC Polyomavirus Infection in Hematopoietic Stem Cell Transplant Recipients.
  Jeremy D. Rubinstein, Sonata Jodele, Daria Heyenbruch, Jamie Wilhelm, Shawn Thomas, Carolyn Lutzko, Xiang Zhu, Thomas Leemhuis, Jose A. Cancelas, Michael D. Keller, Ca...> ;Transplantation and Cellular Therapy. 2021 Nov 13
• 3 citations
  Evaluation and Treatment of Febrile Ulceronecrotic Mucha-Habermann Disease With Ruxolitinib and Tocilizumab as Guided by Cytokine Profile.
  Richard Wu, Ashley DiLorenzo, Michael Lotke, Kaiane A. Habeshian, Joel P. Brooks, Michael D. Keller, A. Yasmine Kirkorian> ;JAMA Dermatology. 2021 Oct 13
• 21 citations
  Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted.
  Jeremy D. Rubinstein, Xiang Zhu, Thomas Leemhuis, Giang Pham, Lorraine Ray, Sana Emberesh, Sonata Jodele, Shawn Thomas, Jose A. Cancelas, Catherine M. Bollard, Patrick...> ;Blood Advances. 2021 Sep 14
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Journal Articles

• Adoptive Immunotherapy for Primary Immunodeficiency Disorders with Virus-Specific T-lymphocytes  
  Naik S, Nicholas SK, Martinez CA, Leen AM, Hanley PJ, Gottschalk SM, Rooney CM, Hanson IC, Krance RA, Shpall EJ, Cruz CR, Amrolia P, Lucchini G, Bunin N, Heimall J, Kl..., J Allergy Clin Immunol
• Major histocompatibility complex class II deficiency due to a novel mutation in RFXANK in a child of Mexican descent  
  Clarridge K, Leitenberg D, Loechelt B, Picard C, Keller MD, Journal of Clinical Immunology, 1/2016
• Mutation in IRF2BP2 is responsible for a Familial Form of Common Variable Immunodeficiency Disorder  
  Keller MD, Pandey R, Li D, Glessner J, Tian L, Henrickson S, Chinn IK, Monaco-Shawver L, Heimall J, Hou C, Otieno FG, Jyonouchi S, Calabrese L, van Montfrans J, Orange..., J Allergy Clin Immunol, 2016
• Incidence of Immunodeficiency in 49, XXXXY chromosomal variation.  
  Keller MD, Sadeghin T, Samango-Sprouse C, and Orange JS, Am J Med Genet C
• Chipping away at a mountain: Genomic studies in Common Variable Immunodeficiency.  
  Keller MD, Jyonouchi S, Autoimmun Rev, 12: S1568
• Diagnosis of 22q11.2 Deletion syndrome and Artemis deficiency in two children with T-B-NK+ Immunodeficiency.  
  Heimall J, Keller M, Saltzman R, Bunin N, McDonald-McGinn D, Zakai E, de Villartay JP, Moshous D, Ariue B, McCarthy EA, Devlin BH, Parikh S, Buckley RH, and Markert ML, J Clin Immunol. 32: 1141-1144
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Abstracts/Posters

• IRF2BP2 mutation in familial Common Variable Immunodeficiency identified by Support Vector Algorithm and Whole Exome Sequencing.
  Keller MD, Tian L, Glessner J, Orange JS, Hakonarson H, Oral presentation, European Society of Immunodeficiency
• Severe Combined Immunodeficiency resulting from mutations in MTHFD1.
  Keller MD, Ganesh J, Heltzer M, Paessler M, Bergqvist AG, Baluarte HJ, Watkins D, Rosenblatt D, and Orange JS, Oral abstract, Clinical Immunology Society
• Incidence of Immunodeficiency in Patients with 49-XXXXY Chromosomal Variation.
  Keller MD, Sadeghin T, Samango-Sprouse C, and Orange JS, Poster presentation, AAAAI annual meeting
• A three generational kindred demonstrating Ectodermal Dysplasia and Immunodeficiency (ED-ID) with both NEMO and EDA mutations.
  Keller MD, Orange, JS, Ann. Allergy. 105: A98
• Co-localization of Splenic NK and Dendritic Cells in Perforin-deficient Hemophagocytic Syndrome: Insight into Mechanism of HLH.
  Keller MD, Paessler ME, and Orange JS, JACI, AB90
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