Michael A Levine MD

Professor Emeritus of Pediatrics and Medicine, University Pennsylvania

3615 Civic Center BlvdChildren's Hospital Of Philadelphia, ARC 510APhiladelphia, PA 19104
Phone+1 215-590-3618
Fax+1 215-590-3053

Summary

Dr. Michael Levine is a pediatric endocrinologist based in Philadelphia, PA, with a distinguished career in both clinical and academic settings. He completed his medical education at Drexel University College of Medicine, followed by residencies and fellowships at Johns Hopkins University and the National Institutes of Health Clinical Center. He holds positions as a Professor of Medicine at the University of Pennsylvania and the Lester Baker Endowed Chair in Pediatrics at Children's Hospital of Philadelphia. With extensive experience in pediatric endocrinology, he has contributed to numerous publications on topics like genetic disorders and metabolic conditions. He is involved in clinical trials related to hypercalcemia and hypoparathyroidism. Dr. Levine has been recognized by several awards including the Research Award from the Hypoparathyroidism Association of America.

University of Pennsylvania Carey School of LawMaster of Law, Law, 2022 - 2024
National Institutes of Health Clinical CenterFellowship, Medical Biochemical Genetics, 1980 - 1982
National Institutes of Health Clinical CenterFellowship, Endocrinology, Diabetes, and Metabolism, 1979 - 1982
Johns Hopkins UniversityResidency, Internal Medicine, 1976 - 1979
Drexel University College of MedicineClass of 1976

Research Award Hypoparathyroidism Association of America, 2012
Election to Johns Hopkins University Society of Scholars 2011
Constantine Anast Lectureship Children's Hospital, Boston, Harvard University, 2009

PubMed

Liver-directed base editing ofprevents ectopic calcification in a variant-humanized mouse model of pseudoxanthoma elasticum.
Lauren C Testa, Dora Obiri-Yeboah, Hooda Said, Ping Qu, Michael A Levine
Molecular Therapy. Nucleic Acids. 2025-12-09
2 citations
Improved specificity and efficiency of in vivo adenine base editing therapies with hybrid guide RNAs.
Madelynn N Whittaker, Lauren C Testa, Aidan Quigley, Dominique L Brooks, Sarah A Grandinette
Nature Biomedical Engineering. 2025-10-28
Health-related quality of life in a cohort of 1070 patients with hypoparathyroidism.
Heide Siggelkow, Tamara Vokes, Neil Gittoes, Olulade Ayodele, Maria Luisa Brandi
European Journal of Endocrinology. 2025-09-30

Journal Articles

Diagnosis and Management of Vitamin D Dependent Rickets
Michael Levine, MD, Frontiers in Pediatrics
Obesity Decreases Hepatic 25‐Hydroxylase Activity Causing Low Serum 25‐Hydroxyvitamin D
Michael A Levine, Jeffrey D Roizen, Journal of Bone and Mineral Research
Heterozygous Mutations in TBX1 as a Cause of Isolated Hypoparathyroidism
Hakon Hakonarson, Michael A Levine, The Journal of Clinical Endocrinology and Metabolism

Books/Book Chapters

The Parathyroids: Basic and Clinical Concepts
Michael A. Levine, MDEditors: John Bilezikian Robert Marcus, John Potts, Robert Marcus, Shonni J Silverberg, Michael Levine, Claudio Marcocci.Elsevier, San DiegoEdition Thir,2014
Pediatric Endocrinology
Chapter: Receptor Transduction Pathways Mediating Hormone Action.
Kublaoui B, Levine MAEditors: Mark A. Sperling.SaundersEdition 4th,2014
Diseases of the Parathyroid Glands
Calabria, AC and MA LevineEditors: AA Licata and EV Lerma.Springer2011

Lectures

Guided Presidential Posters: Genetics and Development (including gene regulation)
ENDO 2019 - New Orleans, LA - 3/24/2019
What's New in the Assessment of Bone Metabolism in Children"
5/1/2014
"Lessons from the genome: an update on hypoparathyroidism"
Chicago, IL - 3/1/2014

Other

Monitoring Bone Health in Children and Adolescents.
Levine, MA, Arab Health Magazine, Issue 3, pp 36-40
1/1/2011
Demonstration that Gcm2 Haploinsufficiency Causes Parathyroid Dysfunction.
Ziqiang Y, Opas EE, Vrikshajanani C, Libutti SK, and Levine MA