MichaelJohnMcManusMD

Pediatric Hematology & Oncology • Marshfield, WI

Physician

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Office
1000 N Oak Ave
Marshfield, WI 54449
Phone+1 715-389-3050
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Summary

Dr. Michael McManus, MD is a pediatric hematologist/oncologist in Marshfield, Wisconsin. He is currently licensed to practice medicine in Wisconsin, California, and Minnesota. He is affiliated with Marshfield Medical Center and Aspirus Steven’s Point Hospital & Clinics, Inc..

Education & Training

Mayo Clinic College of Medicine and Science (Rochester)Fellowship, Pediatric Hematology/Oncology, 1988 - 1991
UMass Chan Medical SchoolResidency, Pediatrics, 1983 - 1986
Georgetown University School of MedicineClass of 1983

Certifications & Licensure

CA State Medical License 2000 - Present
MN State Medical License 1988 - 2023
WI State Medical License 2002 - 2023
American Board of Pediatrics Pediatrics

Clinical Trials

Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET Start of enrollment: 2007 Mar 26
Active, not recruiting
Phase 3
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies Start of enrollment: 2008 May 19
Recruiting
Neuropsychological and Behavioral Testing in Younger Patients With Cancer Start of enrollment: 2008 Sep 15
Recruiting
Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer Start of enrollment: 2003 Oct 13
Completed
Study of Kidney Tumors in Younger Patients Start of enrollment: 2006 Feb 27
Recruiting
Collecting and Storing Biological Samples From Patients With Ewing Sarcoma Start of enrollment: 2008 Feb 04
Completed
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma Start of enrollment: 2000 Nov 06
Recruiting
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Start of enrollment: 1999 Mar 15
Completed
Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors Start of enrollment: 2004 Feb 16
Completed
Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor Start of enrollment: 2009 Jul 13
Active, not recruiting
Phase 3
Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma Start of enrollment: 2010 May 07
Active, not recruiting
Phase 3
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2010 Aug 09
Completed
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Start of enrollment: 2010 Aug 09
Active, not recruiting
Phase 3
Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors Start of enrollment: 2010 Nov 22
Completed
Phase 2
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Start of enrollment: 2010 Nov 22
Active, not recruiting
Phase 3
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia Start of enrollment: 2011 Apr 04
Completed
Phase 3
Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation Start of enrollment: 2011 Sep 01
Completed
Phase 3
Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2011 Jun 20
Active, not recruiting
Phase 3
A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum Start of enrollment: 2012 Feb 01
Intergroup Trial for Children or Adolescents With B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients Start of enrollment: 2012 Jun 01
Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma Start of enrollment: 2013 Feb 12
Completed
Phase 2
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Publications & Presentations

PubMed

An 18-month-old Girl with a Fleshy Mass in the Ear Canal.
Yixian Li, Samuel J. Huang, Michael J. McManus> ;Pediatrics in Review. 2021 Jan 1
7 citations
Absidia corymbifera endocarditis: survival after treatment of disseminated mucormycosis with radical resection of tricuspid valve and right ventricular free wall.
Michael E. Mitchell, Michael J. McManus, Julie Dietz, Bruce M. Camitta, Sara Szabo, Peter L. Havens> ;The Journal of Thoracic and Cardiovascular Surgery. 2010 Apr 1
22 citations
Suramin Induces Phosphorylation of the High‐Affinity Nerve Growth Factor Receptor in PC12 Cells and Dorsal Root Ganglion Neurons
Jagjit S. Gill, Denise C. Connolly, Michael J. McManus, Nita J. Maihle, Anthony J. Windebank> ;Journal of Neurochemistry. 2002 Nov 23
22 citations
Activation of Rho Is Required for Ligand-independent Oncogenic Signaling by a Mutant Epidermal Growth Factor Receptor
Julie L. Boerner, Andrew J. Danielsen, Michael J. McManus, Nita J. Maihle> ;The Journal of Biological Chemistry. 2001 Feb 2
32 citations
An oncogenic epidermal growth factor receptor signals via a p21-activated kinase-caldesmon-myosin phosphotyrosine complex.
Michael J. McManus, Julie L. Boerner, Andrew J. Danielsen, Ze Wang, Fumio Matsumura, Nita J. Maihle> ;The Journal of Biological Chemistry. 2000 Nov 10
13 citations
Ras-independent oncogenic transformation by an EGF-receptor mutant.
Julie L. Boerner, Michael J. McManus, G.S. Martin, Nita J. Maihle> ;Journal of Cell Science. 2000 Mar 15
11 citations
Tyrosine Phosphorylation of Caldesmon Is Required for Binding to the Shc·Grb2 Complex
Ze Wang, Andrew J. Danielsen, Nita J. Maihle, Michael J. McManus> ;The Journal of Biological Chemistry. 1999 Nov 19
27 citations
A transformation-associated complex involving tyrosine kinase signal adapter proteins and caldesmon links v-ErbB signaling to actin stress fiber disassembly
Michael J. McManus, Wilma L. Lingle, Jeffrey L. Salisbury, Nita J. Maihle> ;Proceedings of the National Academy of Sciences of the United States of America. 1997 Oct 14
2 citations
Phosphotyrosyl proteins in childhood rhabdomyosarcomas: phosphorylation of catenins and components of the insulin-like growth factor type I receptor signaling cascade.
Michael J. McManus, Hutt Pj, Nita J. Maihle> ;Journal of Pediatric Hematology/oncology. 1997 Jan 1
30 citations
Successful Treatment of Intrathecal Methotrexate Overdose by Using Ventriculolumbar Perfusion and Intrathecal Instillation of Carboxypeptidase G2
Aengus O'Marcaigh, Christopher M. Johnson, William A. Smithson, Marc C. Patterson, Brigitte C. Widemann, Peter C. Adamson, Michael J. McManus> ;Mayo Clinic Proceedings. 1996 Feb 1
2 citations
Bilateral Primary Neuroblastomas in the Inguinal Canal
Mark E. Leo, Michael J. McManus, Lawrence R. Strawbridge, Stephen A. Kramer> ;The Journal of Urology. 1992 Jul 1
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Hospital Affiliations

Marshfield Medical CenterMarshfield, Wisconsin
Aspirus Steven’s Point Hospital & Clinics, Inc.Stevens Point, Wisconsin