MichaelWWoodMD

PubMed

• Bicyclo((aryl)methyl)benzamides as inhibitors of GlyT1.
  Varnes, J. G.,Xiong, H.,Forst, J. M.,Holmquist, C. R.,Ernst, G. E.,Frietze, W.,Dembofsky, B.,Andisik, D. W.,Palmer, W. E.,Hinkley, L.,Steelman, G. B.,Wilkins, D. E.,Ti...> ;Bioorg. Med. Chem. Lett.. 2018 Mar 01
• Fragment-assisted hit investigation involving integrated HTS and fragment screening: Application to the identification of phosphodiesterase 10A (PDE10A) inhibitors.
  Varnes, J. G.,Geschwindner, S.,Holmquist, C. R.,Forst, J.,Wang, X.,Dekker, N.,Scott, C. W.,Tian, G.,Wood, M. W.,Albert, J. S.> ;Bioorg. Med. Chem. Lett.. 2015 Nov 26
• Uropathogenic E. coli promote a paracellular urothelial barrier defect characterized by altered tight junction integrity, epithelial cell sloughing and cytokine release.
  Wood, M. W.,Breitschwerdt, E. B.,Nordone, S. K.,Linder, K. E.,Gookin, J. L.> ;J. Comp. Pathol.. 2011 Oct 22
• 2,6-Disubstituted pyrazines and related analogs as NR2B site antagonists of the NMDA receptor with anti-depressant activity.
  Brown, D.G., Maier, D.L., Sylvester, M.A., Hoerter, T.N., Menhaji-Klotz, E., Lasota, C.C., Hirata, L.T., Wilkins, D.E., Scott, C.W., Trivedi, S., Chen, T., McCarthy, D...> ;Bioorg Med Chem Lett. 2011 Jun 1
• Assessment of urine solute and matrix effects on the performance of an enzyme-linked immunosorbent assay for measurement of interleukin-6 in dog urine.
  Wood, M.W., Nordone, S.K., Vaden, S.L., Breitschwerdt, E.B.> ;J Vet Diagn Invest. 2011 Mar
• Autocrine effects of interleukin-6 mediate acute-phase proinflammatory and tissue-reparative transcriptional responses of canine bladder mucosa.
  Wood, M.W., Breitschwerdt, E.B., Gookin, J.L.> ;Infect Immun. 2011 Feb
• Cystoscopic guided removal of ectopic eggs from the urinary bladder of the Florida cooter turtle (Pseudemys floridana floridana).
  Minter, L.J., Wood, M.W., Hill, T.L., Lewbart, G.A.> ;J Zoo Wildl Med. 2010 Sep
• A homogeneous fluorescent cell-based assay for detection of heterologously expressed nitric oxide synthase activity.
  Wood, M.W., Hastings, R.C., Sygowski, L.A.> ;J Biomol Screen. 2005 Dec
• Actin-binding proteins from Burkholderia mallei and Burkholderia thailandensis can functionally compensate for the actin-based motility defect of a Burkholderia pseudo...
  Stevens, J.M., Ulrich, R.L., Taylor, L.A., Wood, M.W., Deshazer, D., Stevens, M.P., Galyov, E.E.> ;J Bacteriol. 2005 Nov
• A Burkholderia pseudomallei type III secreted protein, BopE, facilitates bacterial invasion of epithelial cells and exhibits guanine nucleotide exchange factor activity.
  Stevens, M.P., Friebel, A., Taylor, L.A., Wood, M.W., Brown, P.J., Hardt, W., Galyov, E.E.> ;J Bacteriol. 2003 Aug
• Identification of a bacterial factor required for actin-based motility of Burkholderia pseudomallei.
  Stevens, M. P., Stevens, J. M., Jeng, R. L., Taylor, L. A., Wood, M. W., Hawes, P., Monaghan, P., Welch, M. D., Galyov, E. E.> ;Mol Microbiol. 2005 Apr
• Attenuated virulence and protective efficacy of a Burkholderia pseudomallei bsa type III secretion mutant in murine models of melioidosis.
  Stevens, M. P., Haque, A., Atkins, T., Hill, J., Wood, M. W., Easton, A., Nelson, M., Underwood-Fowler, C., Titball, R. W., Bancroft, G. J., Galyov, E. E.> ;Microbiology (Reading, Engl). 2004 Aug
• Structural analysis of Salmonella enterica effector protein SopD.
  Wood, M. W., Williams, C., Upadhyay, A., Gill, A. C., Philippe, D. L., Galyov, E. E., van den Elsen, J. M., Bagby, S.> ;Biochim Biophys Acta. 2004 May 6
• Identification of N-(2-(azepan-1-yl)-2-phenylethyl)-benzenesulfonamides as novel inhibitors of GlyT1.
  Varnes, J. G., Forst, J. M., Hoerter, T. N., Holmquist, C. R., Wilkins, D. E., Tian, G., Jonak, G., Wang, X., Potts, W. M., Wood, M. W., Alhambra, C., Brugel, T. A., A...> ;Bioorg Med Chem Lett. 2010 Aug 15
• Cystoscopic-guided balloon dilation of a urethral stricture in a female dog.
  Wood, M. W., Vaden, S., Cerda-Gonzalez, S., Keene, B.> ;Can Vet J. 2007 Jul
• Salmonella typhimurium infection triggers dendritic cells and macrophages to adopt distinct migration patterns in vivo.
  Zhao, C., Wood, M. W., Galyov, E. E., Höpken, U. E., Lipp, M., Bodmer, H. C., Tough, D. F., Carter, R. W.> ;Eur J Immunol. 2006 Nov
• An Inv/Mxi-Spa-like type III protein secretion system in Burkholderia pseudomallei modulates intracellular behaviour of the pathogen.
  Stevens, M. P., Wood, M. W., Taylor, L. A., Monaghan, P., Hawes, P., Jones, P. W., Wallis, T. S., Galyov, E. E.> ;Mol Microbiol. 2002 Nov
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