Miguel Pappolla, MD

Miguel Pappolla, MD

Neurology Houston, TX


Office Address

Office Map
  • 2646 S Loop West Ste 106
    Houston, TX 77054
    Phone: (713) 661-0300
    Fax: (281) 822-0480

Dr. Pappolla's Clinical Specialties & Interests

  • Neurology: Interventional, Pain Medicine

Dr. Pappolla's Faculty Appointments & Work History

  • Private PractitionerSt. Michael’s Pain and Spine Clinics
    Houston, TX
    Clinical Practice Limited to Interventional Pain Management; www.SMPSclinic.com
  • ProfessorUniversity of Texas Medical Branch
    Galveston, TX
  • Pain Fellow- Interventional Pain ManagementUniversity of Mississippi
    Jackson, MS
  • Clinical ProfessorLSU Health Science Center
    New Orleans, LA
  • Chairman and DirectorNeurology Memorial Hospital
    Gulfport, MS
  • Director and Senior PartnerMcGowin Center for Neuroscience (Private Practice Neurology Group)
    Practice and building totally demolished by hurricane Katrina
  • Scientific and Founding DirectorAlzheimer’s Foundation of the South
    Mobile, AL
  • Attending NeuropathologistUniversity of South Alabama College of Medicine
    Mobile, AL
    Associate Professor of Pathology (Neuropathology) and Neurology (1996-2001); Director, Memory Disorders Clinic (1999-2001); Professor of Pathology (Neuropathology) and Associate Professor of Neurology (2001-2004); Director, Neuropathology Division, (2002-2004)
  • Associate Professor of Pathology (Neuropathology)University of Texas Medical School Health Science Center
    Houston, TX
  • Attending Pathologist and NeuropathologistUniversity of Texas Medical School
    Houston, TX
  • Assistant Professor of Pathology (Neuropathology)Mount Sinai Medical School
    New York, NY
  • Attending Pathologist and NeuropathologistBronx VA Medical Center
    Bronx, NY
  • DirectorDepartment of Veteran Affairs
    Washington, DC
  • DirectorMontrose VA Medical Center
    Pathology Residency Program Accredited Research Year Component of Training
  • Associate Professor of Pathology (Neuropathology)New York Medical College
    Clinical Assistant Professor of Pathology (Neuropathology) (1985-1986); Assistant Professor of Pathology (Neuropathology) (1986-1990)
  • Chief of Service Pathology and Laboratory MedicineFDR VA Medical Center
    Montrose, NY
  • Attending PathologistNew York Medical College and Westchester Medical Center
    Valhalla, NY

Dr. Pappolla's Education & Medical Training

  • University of Mississippi Medical CenterUniversity of Mississippi Medical CenterFellowship, Pain Medicine
  • University of MississippiUniversity of MississippiOther Training, Interventional Pain Management (Anesthesia accredited program)
  • University of Catalunya, Barcelona, SpainUniversity of Catalunya, Barcelona, SpainOther Training, PhD, Human Aging, Cum Laude
  • University of South AlabamaUniversity of South AlabamaResidency, Neurology
  • Cleveland Clinic FoundationCleveland Clinic FoundationFellowship, Neuropathology
  • Cleveland Clinic FoundationCleveland Clinic FoundationOther Training, Neuropathology
  • Case Westrn Res University Afl HospitalCase Westrn Res University Afl HospitalFellowship, Neuropathology
  • Case Western Reserve UniversityCase Western Reserve UniversityOther Training, Neuropathology
  • Aultman HospitalAultman HospitalResidency, Anatomic and Clinical Pathology
  • University of Buenos AiresUniversity of Buenos AiresMedical School

Dr. Pappolla's Certifications & Licensure

  • MS State Medical LicenseMS State Medical License2001 - 2014
  • TX State Medical LicenseTX State Medical License1994 - 2014
  • FL State Medical LicenseFL State Medical License1993 - 2015
  • OH State Medical LicenseOH State Medical License1982 - 2014
  • American Board of PathologyAmerican Board of PathologyAnatomic Pathology, 1986
  • American Board of PathologyAmerican Board of PathologyNeuropathology, 1986
  • American Board of PathologyAmerican Board of PathologyClinical Pathology, 1990
  • American Board of Psychiatry and NeurologyAmerican Board of Psychiatry and NeurologyNeurology, 2004
  • American Board of Psychiatry and NeurologyAmerican Board of Psychiatry and NeurologyPain Medicine, 2008

Dr. Pappolla's Awards, Honors, & Recognition

  • Centers for Medicare & Medicaid ServicesMeaningful Use Stage 1 CertificationCenters for Medicare & Medicaid Services, 2012
  • Medical University of South CarolinaJosephine T. Morse Endowed Professorship in NeuropathologyMedical University of South Carolina, 2006
  • LSU Health Sciences Center, New OrleansCommendation Award for Academic Excellence and LeadershipLSU Health Sciences Center, New Orleans, 2006
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Dr. Pappolla's Publications & Presentations

PubMed | Citations by Web of Science®

Journal Articles

  • Targets for AD treatment: conflicting messages from Gamma-secretase inhibitors.Sambamurti K, Greig NH, Utsuki T, Barnwell EL, Sharma E, Mazell C, Bhat NR, Kindy MS, Lahiri DK, Pappolla MA, J Neurochem, 5/1/2011
  • Amphiphilic amide nitrones: a new class of protective agents acting as modifiers of mitochondrial metabolism.J Med Chem, 7/1/2010
  • Differential Accumulation of Secreted AbetaPP Metabolites in Ocular Fluids.Prakasam A, Muthuswamy A, Ablonczy Z, Greig NH, Fauq A, Rao KJ, Pappolla MA, Sambamurti K, J Alzheimers Dis, 4/22/2010
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Books/Book Chapters

  • Neuropathologia Diagnostico Y ClinicaChapter: Molecular Biology and Neuropathology of Alzheimer's Disease.
    Pappolla MA
    Editors: F. Cruz-Sanchez.Edimsa
  • Free Radicals in Brain Pathophysiology.Chapter: The role of Transgenic models for the Study of Oxidative Neurotoxicity in Alzheimer’s Disease.
    M. A. Pappolla, Y-J Chyan, G. Perry, M.A. Smith
    Editors: Poli G and Cadenas E..
  • Alzheimer’s Disease: Biology, Diagnosis and TherapeuticsChapter: Dual Anti-amyloidogenic and Anti-oxidant Properties of Melatonin. A New Therapy for Alzheimer’s Disease?Page 661 - 669
    Pappolla MA, Bozner P, Soto C, Shao H, Brewer G. Robakis NK, Zagorski M, Frangione B, Ghiso J
    Editors: K. Iqbal, B. Winblad, and H.M. Wisniewski.John Wiley & Sons Ltd.
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  • Cognitive Impairment in Familial Heterozygous Hypercholesterolemia.Pappolla MA, Sambamurti K, Pacheco J, et al, World Congress of Alzheimer’s Congress, Chicago, IL., 7/1/2008
  • Isoprenoids Phenocopy Familial AD Mutations And Regulate Gamma Secretase.Sambamurti K, Parkasam A, Venugopal, C, Jayachandran AD, Rao KS, Lahiri DK, Greig NH, Pappolla MA, Zhou Y, The Alzheimer's Association International Conference on Alzheimer's Disease (ICAD) McCormick Place, , 1/1/2008
  • Alzheimer's Amyloid Protein Precursor and Neurotrophins in Age Related Retinal Degeneration.Sambamurti K, Pappolla MA, Granholm A-C, A. Prakasam A, Annual ARVO meeting, FT. Lauderdale, FL., 1/1/2008
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  • "Interventional Pain Modalities for Spine Care. A Short Review". (Invited Speaker)Charleston Spine Symposium. - 8/24/2007
  • Cholesterol metabolism, hyperhomocysteinemia and oxidative stress: Novel therapeutic targets for Alzheimer’s disease. (Invited Symposium Speaker)9th International Conference on Alzheimer’s Disease and Related Disorders, Philadelphia, PA. - 7/1/2004
  • Cholesterol metabolism: A risk factor and potential therapeutic target for Alzheimer’s disease. (Invited Symposium Speaker)8th International Conference on Alzheimer’s Disease and Related Disorders, Stockholm, Sweden. - 7/20/2002
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  • Cholesterol, Oxidative Stress and Alzheimer’s disease. Expanding the Horizons of Pathogenesis. (Review)Pappolla MA, Smith MA, Bryant-Thomas T, Bazan N, Petanceska S, Perry G, Thal LJ, Sano M, Refolo LM, Free Radic Biol Med
  • Inhibition of Alzheimer’s Beta Amyloid Fibril Formation.Pappolla M, Bozner P, Zagorski M, Shao H, Frangione B, Ghiso J, Emerging Therapeutic Targets.
  • Oxygen Free Radicals and Amyloidosis in Alzheimer's Disease: Is There a Connection? Editorial.Robakis NK, Pappolla MA, Neurobiol Aging

Grant Support

  • Cholesterol And Amyloidogenesis
    Cholesterol And AmyloidogenesisNational Institute On Aging
    2004 - 2005
  • Cholesterol And Amyloidogenesis
    Cholesterol And AmyloidogenesisNational Institute On Aging
    2003 - 2003
  • Melatonin- A New Anti-Amyloidogenic &Antioxidant Agent
    Melatonin- A New Anti-Amyloidogenic &Antioxidant AgentNational Institute On Aging
    2003 - 2003
  • Melatonin- A New Anti-Amyloidogenic &Antioxidant Agent
    Melatonin- A New Anti-Amyloidogenic &Antioxidant AgentNational Institute On Aging
    2000 - 2003
  • Melatonin And Antioxidants As Therapeutic Agents
    Melatonin And Antioxidants As Therapeutic AgentsNational Institute On Aging
    1998 - 1998
  • Mutations Oxidative Stress And Amyloidogensis
    Mutations Oxidative Stress And AmyloidogensisNational Institute On Aging
    1996 - 1997
  • Mutations Oxidative Stress And Amyloidogensis
    Mutations Oxidative Stress And AmyloidogensisNational Institute On Aging
    1995 - 1995

Hospital Affiliations

Insurance Accepted

  • Aetna Choice POS II
  • Aetna HMO
  • Anthem Blue Access PPO
  • Anthem Blue Preferred HMO
  • BCBS Blue Card PPO
  • BCBS Illinois PPO
  • BCBS Texas BlueChoice
  • CIGNA Open Access
  • Great West PPO
  • Humana ChoiceCare Network PPO
  • Multiplan PHCS PPO
  • Multiplan PPO
  • United Healthcare - Direct Choice Plus POS
  • United Healthcare - Direct Options PPO

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