MurrayBrentSteinMDMPH

Psychopharmacology

Distinguished Professor of Psychiatry and Public Health and Vice Chair for Clinical Research in Psychiatry at the University of California San Diego (UCSD)

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Office
9500 Gilman Drive
La Jolla, CA 92093
Phone+1 858-534-6451
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Summary

Dr. Murray Stein is a psychiatrist in La Jolla, CA and is affiliated with VA San Diego Healthcare System and UC San Diego Health. He received his medical degree from University of Manitoba and has been in practice 35 years. He specializes in psychopharmacology and is experienced in anxiety and traumatic stress disorders.

Education & Training

National Institutes of Health Clinical CenterResidency, Psychiatry, 1989 - 1990
National Institutes of Health Clinical CenterResidency, Psychiatry, 1986 - 1988
University of ManitobaClass of 1983

Certifications & Licensure

CA State Medical License 1994 - 2026
MD State Medical License 1986 - 1995
American Board of Psychiatry and Neurology Psychiatry

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2002-2014
Top Doctors:San Diego Area Castle Connolly, 2013
Top Doctors:Southern California Castle Connolly, 2012
Women's Health Castle Connolly, 2008
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Clinical Trials

Experimental Medication For the Treatment of Generalized Anxiety Disorder Start of enrollment: 2004 Nov 01
Completed
Phase 3
A Long-Term Study Continuing on From Study 04-001-01 of an Experimental Medication in Adults With Anxiety Disorder Start of enrollment: 2005 Mar 01
Completed
Phase 3
Efficacy and Tolerability of Atomoxetine (Strattera) in Adult Patients With Generalized Social Anxiety Disorder Start of enrollment: 2005 Nov 01
Completed
Phase 2, Phase 3
Improving Treatment Outcomes in Pharmacotherapy of Generalized Social Anxiety Disorder Start of enrollment: 2006 Mar 01
Completed
Phase 4
Primary Care Intervention Strategy for Anxiety Disorders Start of enrollment: 2006 Jun 01
Completed
Phase 4
PharmacofMRI (Functional Magnetic Resonance Imaging) of Anxiolytic Medications (Alprazolam) Start of enrollment: 2008 Jan 01
Completed
Phase 4
Trial of Hydrocortisone for Post-Traumatic Stress Disorder (PTSD) Start of enrollment: 2009 Aug 01
Withdrawn
Phase 4
PharmacofMRI of Anxiolytic Medications (Pregabalin) Start of enrollment: 2008 Jun 01
Completed
Phase 4
Neural Functioning Underlying Anxiety and Its Treatment (The INSULA Study) Start of enrollment: 2007 Oct 01
Completed
Not Applicable
Post-Deployment Afghanistan/Iraq Trauma Related Inventory of Traits (PATRIOT): Phase 1 (Feasibility Study) Start of enrollment: 2011 Sep 01
Completed
Imaging Outcomes of Cognitive Behavioral Therapy (CBT) for Battered Women With Posttraumatic Stress Disorder Start of enrollment: 2008 Jan 01
Completed
Not Applicable
PROlonGed ExpoSure Sertraline Start of enrollment: 2011 Nov 01
Completed
Phase 4
Genomics of Posttraumatic Stress Disorder in Veterans Start of enrollment: 2013 Dec 01
Active, not recruiting
Negative-Positive Valence Domains in Anxiety and Depression Start of enrollment: 2013 Sep 01
Completed
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Publications & Presentations

PubMed

Genetic influences and causal pathways shared between cannabis use disorder and other substance use traits.
Marco Galimberti, Daniel F Levey, Joseph D Deak, Hang Zhou, Murray B Stein, Joel Gelernter> ;Molecular Psychiatry. 2024 Apr 5
Effects of genetically predicted posttraumatic stress disorder on autoimmune phenotypes.
Adam X Maihofer, Andrew Ratanatharathorn, Sian M J Hemmings, Karen H Costenbader, Vasiliki Michopoulos, Renato Polimanti, Alex O Rothbaum, Soraya Seedat, Elizabeth A M...> ;Translational Psychiatry. 2024 Apr 1
Vulnerabilities in social anxiety: Integrating intra- and interpersonal perspectives.
Rivkah Ginat-Frolich, Eva Gilboa-Schechtman, Jonathan D Huppert, Idan M Aderka, Lynn E Alden, Yair Bar-Haim, Eni S Becker, Amit Bernstein, Ronny Geva, Richard G Heimbe...> ;Clinical Psychology Review. 2024 Apr 1
Impact of PTSD treatment on postconcussive symptoms in veterans: A comparison of sertraline, prolonged exposure, and their combination.
Katherine E Porter, Peter P Grau, H Myra Kim, Corey Powell, Margaret R Venners, Erin R Smith, Sheila A M Rauch, , Murray B Stein, Charles W Hoge, Brian Martis, Naomi M...> ;Journal of Psychiatric Research. 2024 May 1
Isolated Traumatic Subarachnoid Hemorrhage on Head Computed Tomography Scan May Not Be Isolated: A TRACK-TBI Study.
John K Yue, Esther Lim Yuh, Mahmoud M Elguindy, Xiaoying Sun, Thomas Arjan Van Essen, Hansen Deng, Patrick J Belton, Gabriela G Satris, Justin C Wong, Alex Valadka, Fr...> ;Journal of Neurotrauma. 2024 Mar 7
Migraine Prevalence, Environmental Risk, and Comorbidities in Men and Women Veterans.
Marianna Gasperi, Nathaniel M Schuster, Brooke Franklin, Caroline M Nievergelt, Niloofar Afari, Murray B Stein> ;JAMA Network Open. 2024 Mar 4
Pleiotropy and genetically inferred causality linking multisite chronic pain to substance use disorders.
Dora Koller, Eleni Friligkou, Brendan Stiltner, Gita A Pathak, Solveig Løkhammer, Daniel F Levey, Hang Zhou, Alexander S Hatoum, Joseph D Deak, Rachel L Kember, Jorien...> ;Molecular Psychiatry. 2024 Feb 15
Perspectives of suicide loss survivors: Qualitative analysis of data from a psychological autopsy study of U.S. Army soldiers.
Zuromski, K., Wilks, C., Al-Suwaidi, M., Wittler, E., Scherban, L., Hite, B., Raymond, L., Dempsey, C., Nock, M., Stein, M., Ursano, R., Benedek, D.> ;Suicide & Life-Threatening Behavior. 2024 Feb 14
Genetic contribution to the comorbidity between attention-deficit/hyperactivity disorder and substance use disorders.
Dora Koller, Marina Mitjans, Manuela Kouakou, Eleni Friligkou, Brenda Cabrera-Mendoza, Joseph D Deak, Natalia Llonga, Gita A Pathak, Brendan Stiltner, Solveig Løkhamme...> ;Psychiatry Research. 2024 Mar 1
Predicting Homelessness Among Transitioning U.S. Army Soldiers.
Tsai, J., Szymkowiak, D., Hooshyar, D., Gildea, S., Hwang, I., Kennedy, C., King, A., Koh, K., Luedtke, A., Marx, B., Montgomery, A., O'Brien, R., Petukhova, M., Samps...> ;American Journal of Preventive Medicine. 2024 Feb 3
Polygenic risk for suicide attempt is associated with lifetime suicide attempt in US soldiers independent of parental risk.
Stein, M., Jain, S., Papini, S., Campbell-Sills, L., Choi, K., Martis, B., Sun, X., He, F., Ware, E., Naifeh, J., Aliaga, P., Ge, T., , , , , Smoller, J., Gelernter, J...> ;Journal of Affective Disorders. 2024 Apr 15
Toward personalized care for insomnia in the US Army: a machine learning model to predict response to cognitive behavioral therapy for insomnia.
Gabbay, F., Georg, M., Gildea, S., Kennedy, C., King, A., Sampson, N., Wagner, J., Kessler, R., Wynn, G., Ursano, R., Stein, M., Capaldi, V.> ;Journal of Clinical Sleep Medicine. 2024 Feb 1
2 citations
The definition of treatment resistance in anxiety disorders: a Delphi method-based consensus guideline.
Domschke, K., Seuling, P., Schiele, M., Bandelow, B., Batelaan, N., Bokma, W., Branchi, I., Broich, K., Burkauskas, J., Davies, S., Dell'Osso, B., Fagan, H., Fineberg,...> ;World Psychiatry. 2024 Feb 1
Genetic architecture distinguishes tinnitus from hearing loss.
Clifford, R., Maihofer, A., Chatzinakos, C., Coleman, J., Daskalakis, N., Gasperi, M., Hogan, K., Mikita, E., Tcheandjieu, C., Telese, F., Zuo, Y., Ryan, A., Nievergel...> ;Nature Communications. 2024 Jan 19
A genome-wide investigation into the underlying genetic architecture of personality traits and overlap with psychopathology.
Gupta, P., Galimberti, M., Liu, Y., Beck, S., Adhikari, K., , Levey, D., Wingo, A., Wingo, T., Stein, M., Gelernter, J.> ;Medrxiv. 2024 Jan 17
Positive and negative affect change following psychotherapeutic treatment for anxiety-related disorders: A systematic review and meta-analysis.
Hoffman, S., Rassaby, M., Taylor, C., Stein, M.> ;Journal of Affective Disorders. 2024 Mar 15
1 citations
Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference.
Xiangrui Meng, Georgina Navoly, Olga Giannakopoulou, Daniel F Levey, Dora Koller, Gita A Pathak, Nastassja Koen, Kuang Lin, Mark J Adams, Miguel E Rentería, Yanzhe Fen...> ;Nature Genetics. 2024 Feb 1
Reciprocal and Indirect Effects Among Intervention, Perceived Social Support, and Anxiety Sensitivity Within a Randomized Controlled Trial for Anxiety Disorders.
Metts, A., Sherbourne, C., Craske, M., Roy-Byrne, P., Stein, M., Bystritsky, A.> ;Behavior Therapy. 2024 Jan 1
Uncommon Protein-Coding Variants Associated With Suicide Attempt in a Diverse Sample of U.S. Army Soldiers.
Wilkerson, M., Hupalo, D., Gray, J., Zhang, X., Wang, J., Girgenti, M., Alba, C., Sukumar, G., Lott, N., Naifeh, J., Aliaga, P., Kessler, R., Turner, C., Pollard, H., ...> ;Biological Psychiatry. 2023 Dec 21
5 citations
Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals.
Zhou, H., Kember, R., Deak, J., Xu, H., Toikumo, S., Yuan, K., Lind, P., Farajzadeh, L., Wang, L., Hatoum, A., Johnson, J., Lee, H., Mallard, T., Xu, J., Johnston, K.,...> ;Nature Medicine. 2023 Dec 1
Optimism, Sociability, and the Risk of Future Suicide Attempt among U.S. Army Soldiers.
James A Naifeh, Robert J Ursano, Murray B Stein, Holly B Herberman Mash, Pablo A Aliaga, Carol S Fullerton, Rachel Shor, Tzu-Cheg Kao, Nancy A Sampson, Ronald C Kessler> ;Military Medicine. 2023 Nov 28
7 citations
Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications.
Daniel F Levey, Marco Galimberti, Joseph D Deak, Frank R Wendt, Arjun Bhattacharya, Dora Koller, Kelly M Harrington, Rachel Quaden, Emma C Johnson, Priya Gupta, Mahant...> ;Nature Genetics. 2023 Dec 1
2 citations
Brainwide Mendelian Randomization Study of Anxiety Disorders and Symptoms.
Mihaela-Diana Zanoaga, Jun He, Gita A Pathak, Dora Koller, Brenda Cabrera-Mendoza, Murray B Stein, Renato Polimanti, Eleni Friligkou> ;Biological Psychiatry. 2024 Apr 15
14 citations
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.
Anna R Docherty, Niamh Mullins, Allison E Ashley-Koch, Xuejun Qin, Jonathan R I Coleman, Andrey Shabalin, JooEun Kang, Balasz Murnyak, Frank Wendt, Mark Adams, Adrian ...> ;The American Journal of Psychiatry. 2023 Oct 1
1 citations
Genetic Decomposition of the Heritable Component of Reported Childhood Maltreatment.
Abigail R Ter Kuile, Christopher Hübel, Rosa Cheesman, Jonathan R I Coleman, Alicia J Peel, Daniel F Levey, Murray B Stein, Joel Gelernter, Christopher Rayner, Thalia ...> ;Biological Psychiatry Global Open Science. 2023 Oct 1
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Journal Articles

Precision Psychiatry—Yes, but Precisely What?—Reply
Jordan W Smoller, Murray B Stein, JAMA
Predeployment Predictors of Psychiatric Disorder‐Symptoms and Interpersonal Violence During Combat Deployment
David M Benedek, Matthew K Nock, Murray B Stein, Robert J Ursano, Depression and Anxiety
The Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS): Progress Toward Understanding Suicide Among Soldiers
Murray B Stein, Robert J Ursano, Nature
Associations of Time-Related Deployment Variables with Risk of Suicide Attempt Among Soldiers
Gary H Wynn, Robert J Ursano, Murray B Stein, JAMA
Review Interoception and Mental Health: A Roadmap
Richard D Lane, Oliver G Cameron, Murray B Stein, Martin P Paulus, Jamie D Feusner, Charles B Nemeroff, ScienceDirect
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Other

American Psychiatric Association Publishing
Murray Stein, MD, National Institutes of Health
https://www.doximity.com/articles/faf4fa8f-7173-4c07-913f-aff08f7c8714
UpToDate, Wolters Kluwer Health - 2013-02-27
American Psychiatric Association Publishing
Murray Stein, MD, PubMed
https://www.doximity.com/articles/faf4fa8f-7173-4c07-913f-aff08f7c8714
UpToDate, Wolters Kluwer Health - 2011-07-11

Press Mentions

Bionomics Reports Promising Full Results Analysis from PREVAIL Phase 2 Study of BNC210 Social Anxiety Disorder (SAD)March 9th, 2023
Polygenic Risk Scores and Genetics in PsychiatryNovember 1st, 2022
Bionomics to Host KOL Webinar on BNC210 and Social Anxiety DisorderSeptember 21st, 2022
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Grant Support

Modifiable Risk And Protective Factors For Suicidal Behaviors In The US ArmyNational Institute Of Mental Health2010–2011
Neural Substrates Of Anticipation And Interoception In Anxiety DisordersNational Institute Of Mental Health2007–2011
Improving Outcomes And Understanding Response Heterogeneity In Anxiety DisordersNational Institute Of Mental Health2007–2011
Improving Outcomes In Pharmacotherapy Of Social PhobiaNational Institute Of Mental Health2005–2009
Calm: Improving Primary Care Anxiety OutcomesNational Institute Of Mental Health2005–2009
Pharmacological FMRI To Identify New Anxiolytics: A Human BioassayNational Institute Of Mental Health2007–2008
Pharmacofmri To Identify New Anxiolytics: A Human BioassayNational Institute Of Mental Health2006
Neural Substrates Of Decision-Making In AnxietyNational Institute Of Mental Health2003–2006
Improving Patient Outcomes In Anxiety DisordersNational Institute Of Mental Health2001–2005
Genetic Polymorphism And Human BehaviorNational Center For Research Resources1998–2005
Paroxetine Treatment And Social Phobia: A PET StudyNational Center For Research Resources2004
Preventing Psychiatric Sequelae Of Traumatic InjuryNational Institute Of Mental Health2001–2003
Effect Of Tryptophan Free Drink On Social Phobic PatientNational Center For Research Resources2000–2002
Improving Care For Panic Disorder In Primary CareNational Institute Of Mental Health1999–2002
Serotonergic Functioning In Social PhobiaNational Center For Research Resources1999
Pregabalin In Social PhobiaNational Center For Research Resources1999
Neurobiology Of Severe Psychological Trauma In WomenNational Center For Research Resources1999
Central Adrenergic Functioning In Social Phobia And ShynessNational Center For Research Resources1999
Assessment Of Panic &Other Anxiety Disorders In Primary CareNational Center For Research Resources1999
Lifetime Traumatic Events StudyNational Center For Research Resources1997–1999
Specificity Of Noradrenergic Dysfunction In Postraumatic Stress DisorderNational Center For Research Resources1998

Hospital Affiliations

Jennifer Moreno Department of Veterans Affairs Medical CenterSan Diego, California