NeilFreedmanMD

PubMed

• 1 citations
  Phosphorylation of USP20 on Ser334 by IRAK1 promotes IL-1β-evoked signaling in vascular smooth muscle cells and vascular inflammation.
  Lisheng Zhang, Jiao-Hui Wu, Pierre-Yves Jean-Charles, Pavitra Murali, Wenli Zhang, Aeva Jazic, Suneet Kaur, Igor Nepliouev, Jonathan A Stiber, Kamie Snow, Neil J Freed...> ;The Journal of Biological Chemistry. 2023 Jul 1
• From Colon to Aortic Aneurysm: Trek of the Treg.
  Neil J Freedman> ;JACC. Basic to Translational Science. 2022 Sep 1
• 9 citations
  Drebrin attenuates atherosclerosis by limiting smooth muscle cell transdifferentiation
  Jiao-Hui Wu, Lisheng Zhang, Igor Nepliouev, Leigh Brian, Tai-Qin Huang, Kamie P. Snow, Brandon M. Schickling, Elizabeth R. Hauser, Francis J. Miller, Neil J. Freedman,...> ;Cardiovascular Research. 2021 Apr 29
• 6 citations
  Drebrin regulates angiotensin II-induced aortic remodelling.
  Lisheng Zhang, Jiao-Hui Wu, Tai-Qin Huang, Igor Nepliouev, Leigh Brian, Zhu-Shan Zhang, Virginia Wertman, Nathan P. Rudemiller, Timothy J. McMahon, Sudha K. Shenoy, Fr...> ;Cardiovascular Research. 2018 Nov 1
• 23 citations
  USP20 (Ubiquitin-Specific Protease 20) Inhibits TNF (Tumor Necrosis Factor)-Triggered Smooth Muscle Cell Inflammation and Attenuates Atherosclerosis.
  Pierre-Yves Jean-Charles, Jiao-Hui Wu, Lisheng Zhang, Suneet Kaur, Igor Nepliouev, Jonathan A. Stiber, Leigh Brian, Rui Qi, Virginia Wertman, Sudha K. Shenoy, Neil J. ...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2018 Oct 1
• 17 citations
  Regulation of inflammation by β-arrestins: Not just receptor tales.
  Neil J. Freedman, Sudha K. Shenoy> ;Cellular Signalling. 2018 Jan 1
• 10 citations
  Interleukin-9 mediates chronic kidney disease-dependent vein graft disease: a role for mast cells.
  Lisheng Zhang, Jiao-Hui Wu, James C. Otto, Susan B. Gurley, Elizabeth R. Hauser, Sudha K. Shenoy, Karim Nagi, Leigh Brian, Virginia Wertman, Natalie K Mattocks, Jeffre...> ;Cardiovascular Research. 2017 Nov 1
• 43 citations
  C-X-C Motif Chemokine Receptor 3 Splice Variants Differentially Activate Beta-Arrestins to Regulate Downstream Signaling Pathways.
  Jeffrey S. Smith, Priya Alagesan, Nimit K. Desai, Thomas F. Pack, Jiao-Hui Wu, Asuka Inoue, Neil J. Freedman, Sudarshan Rajagopal> ;Molecular Pharmacology. 2017 Jan 1
• 35 citations
  Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation.
  Pierre-Yves Jean-Charles, Lisheng Zhang, Jiao-Hui Wu, Sang-oh Han, Leigh Brian, Neil J. Freedman, Sudha K. Shenoy> ;The Journal of Biological Chemistry. 2016 Apr 1
• 13 citations
  The Actin-Binding Protein Drebrin Inhibits Neointimal Hyperplasia
  Jonathan A. Stiber, Jiao-Hui Wu, Lisheng Zhang, Igor Nepliouev, Zhu-Shan Zhang, Victoria Bryson, Leigh Brian, Rex C. Bentley, Phillip R. Gordon-Weeks, Paul B. Rosenber...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2016 Mar 24
• 14 citations
  Chapter Nine - Cellular Roles of Beta-Arrestins as Substrates and Adaptors of Ubiquitination and Deubiquitination
  Pierre-Yves Jean-Charles, Neil J. Freedman, Sudha K. Shenoy> ;Progress in Molecular Biology and Translational Science. 2016 Jan 1
• 70 citations
  Kruppel-like factor 15 is critical for vascular inflammation
  Yuan Lu, Lisheng Zhang, Xudong Liao, Panjamaporn Sangwung, Domenick A. Prosdocimo, Guangjin Zhou, Alexander R. Votruba, Leigh Brian, Yuh Jung Han, Huiyun Gao, Yunmei W...> ;The Journal of Clinical Investigation. 2013 Oct 1
• 36 citations
  Immunoglobulin-like domain containing receptor 1 mediates fat-stimulated cholecystokinin secretion
  Rashmi Chandra, Yu Wang, Rafiq A. Shahid, Steven R. Vigna, Neil J. Freedman, Rodger A. Liddle> ;The Journal of Clinical Investigation. 2013 Aug 1
• 39 citations
  Kalirin Promotes Neointimal Hyperplasia by Activating Rac in Smooth Muscle Cells
  Jiao-Hui Wu, Alexander C. Fanaroff, Krishn C. Sharma, Liisa S. Smith, Leigh Brian, Betty A. Eipper, Richard E. Mains, Neil J. Freedman, Lisheng Zhang> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2013 Apr 1
• 49 citations
  MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β2-adrenergic receptors
  Sang-oh Han, Kunhong Xiao, Jihee Kim, Jiao-Hui Wu, James W. Wisler, Nobuhiro Nakamura, Neil J. Freedman, Sudha K. Shenoy> ;The Journal of Cell Biology. 2012 Nov 26
• 8 citations
  Vein graft neointimal hyperplasia is exacerbated by CXCR4 signaling in vein graft-extrinsic cells
  Lisheng Zhang, Leigh Brian, Neil J. Freedman> ;Journal of Vascular Surgery. 2012 Nov 1
• 39 citations
  G Protein–Coupled Receptor Kinase-5 Attenuates Atherosclerosis by Regulating Receptor Tyrosine Kinases and 7-Transmembrane Receptors
  Jiao-Hui Wu, Lisheng Zhang, Alexander C. Fanaroff, Xinjiang Cai, Krishn C. Sharma, Leigh Brian, Sabrina T. Exum, Sudha K. Shenoy, Karsten Peppel, Neil J. Freedman> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2012 Feb 1
• 29 citations
  Human Umbilical Cord Blood–Derived Endothelial Cells Reendothelialize Vein Grafts and Prevent Thrombosis
  Melissa A. Brown, Lisheng Zhang, Vrad W. Levering, Jiao-Hui Wu, Lisa L. Satterwhite, Leigh Brian, Neil J. Freedman, George A. Truskey> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2010 Nov 1
• 15 citations
  Human umbilical cord blood endothelial progenitor cells decrease vein graft neointimal hyperplasia in SCID mice.
  Shoukang Zhu, Anuj Malhotra, Lisheng Zhang, Shanming Deng, Taifang Zhang, Neil J. Freedman, Robert W. Storms, Karsten Peppel, Pascal J. Goldschmidt-Clermont, Chunming ...> ;Atherosclerosis. 2010 Sep 1
• 30 citations
  Aging-related atherosclerosis is exacerbated by arterial expression of tumor necrosis factor receptor-1: evidence from mouse models and human association studies
  Lisheng Zhang, Jessica J. Connelly, Karsten Peppel, Leigh Brian, Svati H. Shah, Sarah C. Nelson, David R. Crosslin, Tianyuan Wang, Andrew S. Allen, William E. Kraus, S...> ;Human Molecular Genetics. 2010 Jul 15
• 12 citations
  Reciprocal Regulation of the Platelet-Derived Growth Factor Receptor-β and G Protein-Coupled Receptor Kinase 5 by Cross-Phosphorylation: Effects on Catalysis
  Xinjiang Cai, Jiao-Hui Wu, Sabrina T. Exum, Martin Oppermann, Richard T. Premont, Sudha K. Shenoy, Neil J. Freedman> ;Molecular Pharmacology. 2009 Mar 1
• 81 citations
  Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis.
  Svati H. Shah, Neil J. Freedman, Lisheng Zhang, David R. Crosslin, David H. Stone, Carol Haynes, Jessica S. Johnson, Sarah C. Nelson, Liyong Wang, Jessica J. Connelly,...> ;Plos Genetics. 2009 Jan 2
• 150 citations
  NEDD4 mediates agonist-dependent ubiquitination, lysosomal targeting and degradation of the β2 adrenergic receptor
  Sudha K. Shenoy, Kunhong Xiao, Vidya Venkataramanan, Peter M. Snyder, Neil J. Freedman, Allan M. Weissman> ;The Journal of Biological Chemistry. 2008 Aug 8
• 85 citations
  β-Arrestins Regulate Atherosclerosis and Neointimal Hyperplasia by Controlling Smooth Muscle Cell Proliferation and Migration
  Jihee Kim, Lisheng Zhang, Karsten Peppel, Jiao Hui Wu, David A. Zidar, Leigh Brian, Scott M. DeWire, Sabrina T. Exum, Robert J. Lefkowitz, Neil J. Freedman> ;Circulation Research. 2008 Jul 3
• 22 citations
  Polymorphisms of the tumor suppressor gene LSAMP are associated with left main coronary artery disease.
  Liyong Wang, Elizabeth R. Hauser, Svati H. Shah, David Seo, Perumal Sivashanmugam, Sabrina T. Exum, Simon G. Gregory, Christopher B. Granger, Jonathan L. Haines, Chris...> ;Annals of Human Genetics. 2008 Jul 1
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Journal Articles

• Drebrin Regulates Angiotensin II-Induced Aortic Remodeling  
  Neil J Freedman, Jonathan A Stiber, Timothy J McMahon, Steven D Crowley, Cardiovascular Research

Other

• Intensive care for oncology patients: Short-term prognosis 
  Freedman N, Hansen-Flaschen J
  http://www.uptodate.com/contents/intensive-care-for-oncology-patients-short-term-prognosis
  UpToDate, Wolters Kluwer Health - 2012-09-14
• Quantifying sleepiness 
  Freedman N
  http://www.uptodate.com/contents/quantifying-sleepiness
  UpToDate, Wolters Kluwer Health - 2012-10-19