PJamesNewmanMD

PubMed

• 5 citations
  Generation of PECAM‐1 (CD31) conditional knockout mice
  Huiying Zhi, Taisuke Kanaji, Guoping Fu, Debra K. Newman, Peter J. Newman> ;Genesis. 2020 Feb 1
• 10 citations
  Platelet Function Changes during Neonatal Cardiopulmonary Bypass Surgery: Mechanistic Basis and Lack of Correlation with Excessive Bleeding
  Nicole M. J. Zwifelhofer, Rachel S. Bercovitz, Regina Cole, Ke Yan, Pippa Simpson, Alyssa J. Moroi, Peter J. Newman, Robert A. Niebler, John P. Scott, Eckehard A. D. S...> ;Thrombosis and Haemostasis. 2020 Jan 1
• 10 citations
  Bioengineered iPSC-derived megakaryocytes for the detection of platelet-specific patient alloantibodies
  Nanyan Zhang, Sentot Santoso, Richard H. Aster, Brian R. Curtis, Peter J. Newman> ;Blood. 2019 Nov 28
• 3 citations
  Diacylglycerol kinase ζ is a negative regulator of GPVI-mediated platelet activation
  Alyssa J. Moroi, Nicole M. J. Zwifelhofer, Matthew J. Riese, Debra K. Newman, Peter J. Newman> ;Blood Advances. 2019 Apr 9
• 7 citations
  Hemizygosity for the gene encoding glycoprotein Ibβ is not responsible for macrothrombocytopenia and bleeding in patients with 22q11 deletion syndrome.
  Nicole M. J. Zwifelhofer, Rachel S. Bercovitz, L A Weik, Alyssa J. Moroi, S LaRose, Peter J. Newman, Debra K. Newman> ;Journal of Thrombosis and Haemostasis. 2019 Feb 1
• 22 citations
  The Role of Sialylated Glycans in Human Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1)-mediated Trans Homophilic Interactions and Endothelial Cell Barrier Fun...
  Panida Lertkiatmongkol, Cathy Paddock, Debra K. Newman, Jieqing Zhu, Michael J. Thomas, Peter J. Newman> ;The Journal of Biological Chemistry. 2016 Dec 9
• 11 citations
  Integrin-αIIbβ3-mediated outside-in signalling activates a negative feedback pathway to suppress platelet activation.
  Baiyun Dai, Peng Wu, Feng Xue, Renchi Yang, Ziqiang Yu, Kesheng Dai, Changgeng Ruan, Gang Liu, Peter J. Newman, Cunji Gao> ;Thrombosis and Haemostasis. 2016 Jul 28
• 270 citations
  Endothelial functions of platelet/endothelial cell adhesion molecule-1 (CD31)
  Panida Lertkiatmongkol, Danying Liao, Heng Mei, Yu Hu, Peter J. Newman> ;Current Opinion in Hematology. 2016 May 1
• 52 citations
  Antiendothelial αvβ3 Antibodies Are a Major Cause of Intracranial Bleeding in Fetal/Neonatal Alloimmune Thrombocytopenia
  Sentot Santoso, Hevi Wihadmadyatami, Tamam Bakchoul, Silke Werth, Nadia Al-Fakhri, Gregor Bein, Volker Kiefel, Jieqing Zhu, Peter J. Newman, Behnaz Bayat, Ulrich J. Sachs> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2016 Jan 1
• 22 citations
  Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase.
  Huiying Zhi, Jing Dai, Junling Liu, Jieqing Zhu, Debra K. Newman, Cunji Gao, Peter J. Newman> ;Plos One. 2015 Aug 20
• 29 citations
  PTH Receptor Signaling in Osteoblasts Regulates Endochondral Vascularization in Maintenance of Postnatal Growth Plate
  Tao Qiu, Lingling Xian, Janet L. Crane, Chunyi Wen, Matthew J. Hilton, William W. Lu, Peter J. Newman, Xu Cao> ;Journal of Bone and Mineral Research. 2015 Feb 1
• 37 citations
  Inhibition of HPA-1a alloantibody-mediated platelet destruction by a deglycosylated anti-HPA-1a monoclonal antibody in mice: toward targeted treatment of fetal-alloimm...
  Tamam Bakchoul, Andreas Greinacher, Ulrich J. Sachs, Annika Krautwurst, Harald Renz, Habi Harb, Gregor Bein, Peter J. Newman, Sentot Santoso> ;Blood. 2013 Jul 18
• 42 citations
  Cadherin 6 Has a Functional Role in Platelet Aggregation and Thrombus Formation
  Eimear Dunne, Christopher M. Spring, Adili Reheman, Wuxun Jin, Michael C. Berndt, Debra K. Newman, Peter J. Newman, Heyu Ni, Dermot Kenny> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2012 Jul 1
• 39 citations
  GPIbα regulates platelet size by controlling the subcellular localization of filamin
  Taisuke Kanaji, Jerry Ware, Takashi Okamura, Peter J. Newman> ;Blood. 2012 Mar 22
• 13 citations
  PECAM-1 functions as a negative regulator of laminin-induced platelet activation.
  Jimmy Crockett, Debra K. Newman, Peter J. Newman> ;Journal of Thrombosis and Haemostasis. 2010 Jul 1
• 30 citations
  Human platelets circulating in mice: applications for interrogating platelet function and survival, the efficacy of antiplatelet therapeutics, and the molecular basis ...
  Peter J. Newman, Richard H. Aster, Brian Boylan> ;Journal of Thrombosis and Haemostasis. 2007 Jul 1
• 5 citations
  HPA-1a/b(PlA1/A2,Zwa/b): the odyssey of an alloantigen system.
  Richard H. Aster, Peter J. Newman> ;Immunohematology. 2020 Apr 1
• 161 citations
  Nomenclature of human platelet antigens.
  Paul Metcalfe, Nicholas A. Watkins, Willem H. Ouwehand, Cécile Kaplan, Peter J. Newman, Riitta Kekomäki, M. de Haas, Richard H. Aster, Y. Shibata, J. Smith, Volker Kie...> ;Vox Sanguinis. 2003 Oct 1
• 82 citations
  A point mutation in the cysteine-rich domain of glycoprotein (GP) IIIa results in the expression of a GPIIb-IIIa (αIIbβ3) integrin receptor locked in a high-affinity s...
  Catherine Ruiz, Chao-Yan Liu, Qi-Hong Sun, Marianne Sigaud-Fiks, Edith Fressinaud, J.Y. Muller, Paquita Nurden, Alan T. Nurden, Peter J. Newman, Nathalie Valentin> ;Blood. 2001 Oct 15
• 9 citations
  PECAM-1/IgG attenuates peroxynitrite-mediated extremity reperfusion injury.
  Michael M. Farooq, Alexandre Serra, Peter J. Newman, Robert A. Cambria, Gary R. Seabrook, Jonathan B. Towne, Julie A. Freischlag> ;Journal of Vascular Surgery. 2001 Sep 1
• Construction and expression of an enzymatically active form of PECAM-1 containing the phosphatase domain of the protein tyrosine phosphatase, SHP-2.
  Masaaki Noda, Cathy Paddock, Peter J. Newman> ;Protein Expression and Purification. 2001 Jun 1
• 100 citations
  Inhibition of antigen-receptor signaling by Platelet Endothelial Cell Adhesion Molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56(lck).
  Debra K. Newman, Christin Hamilton, Peter J. Newman> ;Blood. 2001 Apr 15
• 116 citations
  Platelet endothelial cell adhesion molecule-1 serves as an inhibitory receptor that modulates platelet responses to collagen.
  Sonali Patil, Debra K. Newman, Peter J. Newman> ;Blood. 2001 Mar 15
• 44 citations
  Integrin Activation by Regulated Dimerization and Oligomerization of Platelet Endothelial Cell Adhesion Molecule (Pecam)-1 from within the Cell
  Tieming Zhao, Peter J. Newman> ;The Journal of Cell Biology. 2001 Jan 8
• 209 citations
  Base excess and lactate as prognostic indicators for patients admitted to intensive care
  I. Smith, P. Kumar, Sean Molloy, Andrew Rhodes, P. J. Newman, RM Grounds, E. D. Bennett> ;Intensive Care Medicine. 2001 Jan 1
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