PamelaSarahCohenMD

PubMed

• 56 citations
  Recombinant tissue plasminogen activator restores perfusion in meningococcal purpura fulminans
  Leslie T. Aiuto, Stephen R. Barone, Pamela S. Cohen, Robert A. Boxer> ;Critical Care Medicine. 1997 Jun 1
• 55 citations
  The biodistribution and radiation dosimetry of the Arg-Gly-Asp peptide 18F-AH111585 in healthy volunteers.
  Brian McParland, Matthew P. Miller, Terence J. Spinks, Laura M. Kenny, Safiye Osman, Mandeep Khela, Eric O. Aboagye, Raoul Charles Coombes, Ai-Min Hui, Pamela S. Cohen> ;Journal of Nuclear Medicine. 2008 Oct 1
• 226 citations
  Phase I Trial of the Positron-Emitting Arg-Gly-Asp (RGD) Peptide Radioligand 18F-AH111585 in Breast Cancer Patients
  Laura M. Kenny, R. Charles Coombes, Inger Oulie, Kaiyumars B. Contractor, Matthew P. Miller, Terence J. Spinks, Brian McParland, Pamela S. Cohen, Ai-Min Hui, Carlo Pal...> ;Journal of Nuclear Medicine. 2008 Jun 1
• 44 citations
  KIT oncoprotein interactions in gastrointestinal stromal tumors: therapeutic relevance.
  Meijun Zhu, Wen-Bin Ou, Christopher D.M. Fletcher, Patrick Cohen, George D. Demetri, Jonathan A. Fletcher> ;Oncogene. 2007 Sep 27
• 44 citations
  The multikinase inhibitor midostaurin (PKC412A) lacks activity in metastatic melanoma: a phase IIA clinical and biologic study
  Michael Millward, Colin M. House, David D.L. Bowtell, Lorraine K. Webster, Ian N. Olver, Martin Gore, M. Copeman, Kevin Lynch, A. Yap, Y. Wang, P.S. Cohen, John Zalcberg> ;British Journal of Cancer. 2006 Oct 9
• 218 citations
  Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain
  Florian H. Heidel, Fian K. Solem, Frank Breitenbuecher, Daniel B. Lipka, Stefan Kasper, M. H. Thiede, Christian Brandts, Hubert Serve, Johannes Roesel, Francis J. Gile...> ;Blood. 2006 Jan 1
• 191 citations
  Activity of the tyrosine kinase inhibitor PKC412 in a patient with mast cell leukemia with the D816V KIT mutation.
  Jason Gotlib, Caroline Berube, Joseph D. Growney, Ching-Cheng Chen, Tracy I. George, Christopher R. Williams, Tomohiro Kajiguchi, Jia Ruan, Stan L. Lilleberg, Jeffrey ...> ;Blood. 2005 Oct 15
• 84 citations
  Identification of a novel activating mutation (Y842C) within the activation loop of FLT3 in patients with acute myeloid leukemia (AML)
  Thomas Kindler, Frank Breitenbuecher, Stefan Kasper, Eli Estey, Francis J. Giles, Eric J. Feldman, Gerhard Ehninger, Gary J. Schiller, Virginia M. Klimek, Stephen D. N...> ;Blood. 2005 Jan 1
• 136 citations
  PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder.
  Jing Chen, Daniel J. DeAngelo, Jeffery L. Kutok, Ifor R. Williams, Benjamin H. Lee, Martha Wadleigh, Nicole Duclos, Sarah L. Cohen, Jennifer Adelsperger, Rachel Okabe,...> ;Proceedings of the National Academy of Sciences of the United States of America. 2004 Oct 5
• Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway.
  Kovarik P, Stoiber D, Eyers PA, Menghini R, Neininger A, Gaestel M, Cohen P, Decker T> ;Proc. Natl. Acad. Sci. U.S.A.. 1999-11-23
• 28 citations
  Targeted Suppression of Cytokine Production in Monocytes but Not in T Lymphocytes by a Tetravalent Guanylhydrazone (CNI-1493)
  Lars Björk, Kevin J. Tracey, Peter C. Ulrich, Marina Bianchi, Pamela S. Cohen, Karin Åkerlund, Thomas E. Fehniger, Ulf Andersson, Jan Andersson> ;The Journal of Infectious Diseases. 1997 Nov 1
• Expression of stem cell factor and c-kit in human neuroblastoma. The Children's Cancer Group.
  Cohen PS, Chan JP, Lipkunskaya M, Biedler JL, Seeger RC> ;Blood. 1994-11-15
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Journal Articles

• Midostaurin  
  Cohen, JCO