ParagPShahMD

PubMed

• 30 citations
  Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury.
  Tess V. Dupre, Mark A. Doll, Parag P. Shah, Cierra N Sharp, Deanna Siow, Judit Megyesi, James A. Shayman, Alicja Bielawska, Jacek Bielawski, Levi J. Beverly, María Jos...> ;Journal of Lipid Research. 2017 Jul 1
• 16 citations
  MIR155 Regulation of Ubiquilin1 and Ubiquilin2: Implications in Cellular Protection and Tumorigenesis
  Sanjay Yadav, Nishant Singh, Parag P. Shah, David A. Rowbotham, Danial A. Malik, Ankita Srivastav, Jai Shankar, Wan L. Lam, William W. Lockwood, Levi J. Beverly> ;Neoplasia. 2017 Apr 1
• 76 citations
  Repeated administration of low-dose cisplatin in mice induces fibrosis.
  Cierra N Sharp, Mark A. Doll, Tess V. Dupre, Parag P. Shah, Marimuthu Subathra, Deanna Siow, Gavin E. Arteel, Judit Megyesi, Levi J. Beverly, Leah J. Siskind> ;American Journal of Physiology. Renal Physiology. 2016 Mar 15
• 24 citations
  Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death.
  Kumaran Sundaram, Andrew R. Mather, Subathra Marimuthu, Parag P. Shah, Ashley J. Snider, Lina M. Obeid, Yusuf A. Hannun, Levi J. Beverly, Leah J. Siskind> ;The Biochemical Journal. 2016 Mar 15
• 22 citations
  Suramin protects from cisplatin-induced acute kidney injury
  Tess V. Dupre, Mark A. Doll, Parag P. Shah, Cierra N Sharp, Alex Kiefer, Michael T. Scherzer, Kumar Saurabh, Doug Saforo, Deanna Siow, Lavona K. Casson, Gavin E. Artee...> ;American Journal of Physiology. Renal Physiology. 2016 Feb 1
• 50 citations
  Ubiquilin1 represses migration and epithelial-to-mesenchymal transition of human non-small cell lung cancer cells
  Parag P. Shah, William W. Lockwood, Kumar Saurabh, Zimple Kurlawala, Sean P. Shannon, Sabine Waigel, Wolfgang Zacharias, Levi J. Beverly> ;Oncogene. 2015 Mar 26
• 32 citations
  The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets
  Kumar Saurabh, Michael T. Scherzer, Parag P. Shah, Alice S. Mims, William W. Lockwood, Andrew S. Kraft, Levi J. Beverly> ;Oncotarget. 2014 Aug 9
• 65 citations
  PTTG induces EMT through integrin αVβ3-focal adhesion kinase signaling in lung cancer cells.
  Parag P. Shah, Miranda Y. Fong, Sham S. Kakar> ;Oncogene. 2012 Jun 28
• 57 citations
  Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1
  Levi J. Beverly, William W. Lockwood, Parag P. Shah, Hediye Erdjument-Bromage, Harold E. Varmus> ;Proceedings of the National Academy of Sciences of the United States of America. 2012 Jan 17
• 48 citations
  Pituitary tumor transforming gene induces epithelial to mesenchymal transition by regulation of Twist, Snail, Slug, and E-cadherin.
  Parag P. Shah, Sham S. Kakar> ;Cancer Letters. 2011 Dec 1
• 42 citations
  MicroRNA signature of cis-platin resistant vs. cis-platin sensitive ovarian cancer cell lines
  Smriti R. Kumar, Arooshi R. Kumar, Parag P. Shah, Shesh N. Rai, Siva K. Panguluri, Sham S. Kakar> ;Journal of Ovarian Research. 2011 Sep 22
• 29 citations
  Polymorphism in cytochrome P450 1A2 and their interaction with risk factors in determining risk of squamous cell lung carcinoma in men.
  Arvind P. Singh, Mohan C. Pant, Munindra Ruwali, Parag P. Shah, Rajendra Prasad, Neeraj Mathur, Devendra Parmar> ;Cancer Biomarkers. 2011 Jan 1
• 104 citations
  Cathepsin L occupies a vacuolar compartment and is a protein maturase within the endo/exocytic system of Toxoplasma gondii
  Fabiola Parussini, Isabelle Coppens, Parag P. Shah, Scott L. Diamond, Vern B. Carruthers> ;Molecular Microbiology. 2010 Jun 1
• 90 citations
  A Small-Molecule Oxocarbazate Inhibitor of Human Cathepsin L Blocks Severe Acute Respiratory Syndrome and Ebola Pseudotype Virus Infection into Human Embryonic Kidney ...
  Parag P. Shah, Tianhua Wang, Rachel Kaletsky, Michael C. Myers, Jeremy E. Purvis, Huiyan Jing, Donna M. Huryn, Doron C. Greenbaum, Amos B. Smith, Paul Bates, Scott L. ...> ;Molecular Pharmacology. 2010 Aug 1
• 1 citations
  Design, synthesis and biological evaluation of a library of thiocarbazates and their activity as cysteine protease inhibitors.
  Zhuqing Liu, Michael C. Myers, Parag P. Shah, Mary Pat Beavers, Phillip A. Benedetti, Scott L. Diamond, Amos B. Smith, Donna M. Huryn> ;Combinatorial Chemistry & High Throughput Screening. 2010 May 1
• 65 citations
  Evidence for increased cytochrome P450 1A1 expression in blood lymphocytes of lung cancer patients
  Parag P. Shah, Kumar Saurabh, Mohan C. Pant, Neeraj Mathur, Devendra Parmar> ;Mutation Research. 2009 Nov 2
• 26 citations
  Polymorphism in cytochrome P450 2A6 and glutathione S-transferase P1 modifies head and neck cancer risk and treatment outcome.
  Munindra Ruwali, Mohan C. Pant, Parag P. Shah, Bhartendu Nath Mishra, Devendra Parmar> ;Mutation Research. 2009 Oct 2
• 28 citations
  Polymorphism in cytochrome P4501a1 is significantly associated with head and neck cancer risk.
  Arvind P. Singh, Parag P. Shah, Munindra Ruwali, Neeraj Mathur, Mohan C. Pant, Devendra Parmar> ;Cancer Investigation. 2009 Sep 1
• 23 citations
  Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer
  Parag P. Shah, Lauren E Hutchinson, Sham S. Kakar> ;Journal of Ovarian Research. 2009 Aug 27
• 33 citations
  Cytochrome P450 2E1 and head and neck cancer: interaction with genetic and environmental risk factors.
  Munindra Ruwali, Anwar Jamal Khan, Parag P. Shah, Arvind P. Singh, Mohan C. Pant, Devendra Parmar> ;Environmental and Molecular Mutagenesis. 2009 Jul 1
• 17 citations
  Galactose-grafted chylomicron-mimicking emulsion: evaluation of specificity against HepG-2 and MCF-7 cell lines.
  Vikas Jain, Banashree Nath, Girish Gupta, Parag P. Shah, Maqsood A. Siddiqui, Aditya B. Pant, Prabhat Ranjan Mishra> ;The Journal of Pharmacy and Pharmacology. 2009 Mar 1
• 18 citations
  Association of poor metabolizers of cytochrome P450 2C19 with head and neck cancer and poor treatment response
  Sunishtha Singh Yadav, Munindra Ruwali, Parag P. Shah, Neeraj Mathur, Ram Lakhan Singh, Mohan C. Pant, Devendra Parmar> ;Mutation Research. 2008 Sep 26
• 30 citations
  Association of functionally important polymorphisms in cytochrome P4501B1 with lung cancer.
  Parag P. Shah, Arvind P. Singh, Madhu Singh, Neeraj Mathur, Bhartendu Nath Mishra, Mohan C. Pant, Devendra Parmar> ;Mutation Research. 2008 Aug 25
• 19 citations
  Molecular Docking of Cathepsin L Inhibitors in the Binding Site of Papain
  Mary Pat Beavers, Michael C. Myers, Parag P. Shah, Jeremy E. Purvis, Scott L. Diamond, Barry S. Cooperman, Donna M. Huryn, Amos B. Smith> ;Journal of Chemical Information and Modeling. 2008 Jul 4
• 33 citations
  Kinetic Characterization and Molecular Docking of a Novel, Potent, and Selective Slow-Binding Inhibitor of Human Cathepsin L
  Parag P. Shah, Michael C. Myers, Mary Pat Beavers, Jeremy E. Purvis, Huiyan Jing, Heather J. Grieser, Elizabeth R. Sharlow, Andrew D. Napper, Donna M. Huryn, Barry S. ...> ;Molecular Pharmacology. 2008 Jul 1
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