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Office
1501 N Campbell Ave
Room 4303, PO Box 245070
Tucson, AZ 85724Phone+1 520-626-4936Fax+1 520-626-8313- Is this information wrong?
Summary
- Dr. Paul Larson is Professor of Neurosurgery at the University of Arizona and Clinical Director of Neurosurgery at the Southern Arizona VA Health Care System. He is also an associate member of the ASU-Banner Neurodegenerative Diseases Research Center. He specializes in functional neurosurgery, specifically deep brain stimulation for a variety of neurological disorders. Dr. Larson completed medical school at the University of Arizona in 1995, and did his residency training at the University of Louisville. He was a professor in neurological surgery at the University of California, San Francisco from 2001 to 2021.
Dr. Larson is a pioneer in the field of interventional MRI-guided stereotaxy for DBS, laser ablation and drug delivery, and has performed well over 1,000 iMRI procedures. His clinical research team has been the solo or lead group in 10 gene therapy clinical research trials since 2004, and has the world’s largest experience in intracranial delivery of novel therapeutics for neurodegenerative disorders. Dr. Larson also has a significant interest in the neurobiology of tinnitus. His NIH-funded research in this area has led to the discovery of a new brain region involved in auditory perception.
Education & Training
- University of Louisville School of MedicineResidency, Neurological Surgery, 1996 - 2001
- University of Louisville School of MedicineInternship, Surgery, 1995 - 1996
- University of Arizona College of MedicineClass of 1995
Certifications & Licensure
- AZ State Medical License 2021 - 2025
- CA State Medical License 2001 - 2025
- American Board of Neurological Surgery Neurological Surgery
Awards, Honors, & Recognition
- Fellow (FAANS) American Association of Neurological Surgeons
Clinical Trials
- Use of Interventional MRI for Implantation of Deep Brain Stimulator Electrodes Start of enrollment: 2003 Jul 01
- Safety Study of AADC Gene Therapy (VY-AADC01) for Parkinson's Disease Start of enrollment: 2013 Oct 01
- Pilot Study of Deep Brain Stimulation (DBS) in Area LC for Chronic Tinnitus Start of enrollment: 2014 Jan 01
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Publications & Presentations
PubMed
- Intracranial beta activity is a biomarker of circadian and stimulation-induced arousal in obsessive compulsive disorder.De, B., Basich-Pease, G., Norbu, T., Morrison, M., Lee, A., Fan, J., Larson, P., Starr, P., Krystal, A., Frank, A.> ;Brain Stimulation. 2023 Dec 13
- Letter to the Editor: Experiences from a Virtual Neurosurgery Research Conference for Medical Students in Arizona.Ryan Palsma, Katherine Riordan, Nora Griffith, Benjamen Meyer, Jarrod Rulney, Carley Coopwood, Albert Alan, Haley Eversman, Rami Khoshaba, Pedro Aguilar-Salinas, Paul ...> ;World Neurosurgery. 2023 Aug 1
- Procedure-Related Complications in Sham Surgeries for Parkinson's Clinical Trials: A Meta-analysis.Adrian W Gelb, Paul S Larson, Mamaril-Davis, J., James C Mamaril-Davis> ;Movement Disorders. 2023 Jul 1
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Press Mentions
- Aspen Neuroscience Announces First Patient Dosed in First-in-Human Phase 1/2a Clinical Trial of Autologous Neuronal Cell Replacement Therapy for Parkinson's DiseaseApril 17th, 2024
Professional Memberships
- Fellow
- American Society for Stereotactic and Functional NeurosurgeryMember
- World Society of Stereotactic and Functional NeurosurgeryMember
- The Movement Disorder SocietyMember
- Society of Neurological SurgeonsMember
Hospital Affiliations
- UCSF Medical CenterSan Francisco, California
- San Francisco VA Medical CenterSan Francisco, California
- Banner - University Medical Center TucsonTucson, Arizona
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