PaulJLimburgMD

Gastroenterology • Rochester, MN

Gastrointestinal Cancer

Professor, Internal Medicine, Mayo Medical School

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Office
200 First Street SW
Rochester, MN 55905
Phone+1 507-266-4338

Fax+1 507-266-0350
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Education & Training

Mayo Clinic College of Medicine and Science (Rochester)Fellowship, Gastroenterology, 1994 - 1997
Mayo Clinic College of Medicine and Science (Rochester)Residency, Internal Medicine, 1991 - 1994
Mayo Clinic College of MedicineClass of 1991

Certifications & Licensure

MN State Medical License 1992 - 2024
AZ State Medical License 1997 - 1998
American Board of Internal Medicine Gastroenterology

Awards, Honors, & Recognition

Elected Member The American Society for Clinical Investigation, 2011
Fellow (AGAF) American Gastroenterological Association, 2011

Clinical Trials

Sulindac Capsules Compared With Sulindac Tablets in Healthy Volunteers Start of enrollment: 2006 Apr 01
Completed
Not Applicable
Inositol in Preventing Lung Cancer in Current or Former Smokers With Bronchial Dysplasia Start of enrollment: 2008 Nov 01
Completed
Phase 2
Studying Different Formulations of SR13668 in Healthy Volunteers Start of enrollment: 2009 Jun 01
Completed
Phase 1
Vaccine Therapy in Treating Patients With Newly Diagnosed Advanced Colon Polyps Start of enrollment: 2014 Jun 23
Active, not recruiting
Phase 2
Erlotinib Hydrochloride in Reducing Duodenal Polyp Burden in Patients With Familial Adenomatous Polyposis at Risk of Developing Colon Cancer Start of enrollment: 2017 Oct 27
Completed
Phase 2
Dolcanatide in Preventing Colorectal Cancer in Healthy Volunteers Start of enrollment: 2018 Jul 27
Completed
Phase 1
MUC1 Vaccine in Preventing Lung Cancer in Current and Former Smokers at High Risk for Lung Cancer Start of enrollment: 2017 Dec 27
Active, not recruiting
Phase 1
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Publications & Presentations

PubMed

1 citations
Next-Generation Multitarget Stool DNA Test for Colorectal Cancer Screening.
Thomas F Imperiale, Kyle Porter, Julia Zella, Zubin D Gagrat, Marilyn C Olson, Sandi Statz, Jorge Garces, Philip T Lavin, Humberto Aguilar, Don Brinberg, Charles Berke...> ;The New England Journal of Medicine. 2024 Mar 14
Phase I Trial of a Therapeutic DNA Vaccine for Preventing Hepatocellular Carcinoma from Chronic Hepatitis C Virus (HCV) Infection.
Jeffrey M Jacobson, David Zahrieh, Carrie A Strand, Marcia Cruz-Correa, Surakit Pungpapong, Lewis R Roberts, Sumithra J Mandrekar, Luz Maria Rodriguez, Jean Boyer, Ida...> ;Cancer Prevention Research. 2023 Mar 1
Phase I Trial of a Therapeutic DNA Vaccine for Preventing Hepatocellular Carcinoma from Chronic Hepatitis C Virus (HCV) Infection.
Jeffrey M Jacobson, David Zahrieh, Carrie A Strand, Marcia Cruz-Correa, Surakit Pungpapong, Lewis R Roberts, Sumithra J Mandrekar, Luz María Rodriguez, Jean Boyer, Ida...> ;Cancer prevention research (Philadelphia, Pa.). 2022 Dec 7
1 citations
Factors influencing colorectal cancer screening decision-making among average-risk US adults.
Xuan Zhu, Emily Weiser, Joan M Griffin, Paul J Limburg, Lila J Finney Rutten> ;Preventive Medicine Reports. 2022 Dec 1
1 citations
Serrated Polyp Yield at Colonoscopy in Patients with Positive FIT, Positive mt-sDNA, and Colonoscopy Only: Data from the New Hampshire Colonoscopy Registry.
Joseph C Anderson, William M Hisey, Christina M Robinson, Paul J Limburg, Bonny L Kneedler, Lynn F Butterly> ;Cancer Epidemiology, Biomarkers & Prevention. 2023 Feb 6
Three-Year Interval for the Multi-Target Stool DNA Test for Colorectal Cancer Screening: A Longitudinal Study.
Thomas F Imperiale, Philip T Lavin, Tara N Marti, Debbie Jakubowski, Steven H Itzkowitz, Folasade P May, Paul J Limburg, Seth Sweetser, Anas Daghestani, Berger, B. M.,...> ;Cancer Prevention Research. 2023 Feb 6
4 citations
Cost-Effectiveness of Waiving Coinsurance for Follow-Up Colonoscopy after a Positive Stool-Based Colorectal Screening Test in a Medicare Population.
A Mark Fendrick, David Lieberman, Vahab Vahdat, Jing Voon Chen, A Burak Ozbay, Paul J Limburg> ;Cancer Prevention Research. 2022 Oct 4
12 citations
Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures.
Peter Georgeson, Tabitha A Harrison, Bernard J Pope, Syed H Zaidi, Conghui Qu, Robert S Steinfelder, Yi Lin, Jihoon E Joo, Khalid Mahmood, Mark Clendenning, Romy Walke...> ;Nature Communications. 2022 Jun 6
4 citations
Cost-Effectiveness of Outreach Strategies for Stool-Based Colorectal Cancer Screening in a Medicaid Population.
Jordan J Karlitz, A Mark Fendrick, Jay Bhatt, Gloria D Coronado, Sushanth Jeyakumar, Nathaniel J Smith, Marcus Plescia, Durado Brooks, Paul Limburg, David Lieberman> ;Population Health Management. 2022 Jun 1
7 citations
Phase II trial of weekly erlotinib dosing to reduce duodenal polyp burden associated with familial adenomatous polyposis.
N Jewel Samadder, Nathan Foster, Ryan P McMurray, Carol A Burke, Elena Stoffel, Priyanka Kanth, Rohit Das, Marcia Cruz-Correa, E Vilar, Gautam Mankaney, Navtej Buttar,...> ;Gut. 2023 Feb 1
1 citations
Costs of colorectal cancer screening with colonoscopy, including post-endoscopy events, among adults with Medicaid insurance.
Deborah A Fisher, Nicole Princic, Lesley-Ann Miller-Wilson, Kathleen Wilson, Paul Limburg> ;Current Medical Research and Opinion. 2022 May 1
5 citations
Factors Associated With Clinician Recommendations for Colorectal Cancer Screening Among Average-Risk Patients: Data From a National Survey.
Xuan Zhu, Emily Weiser, Debra J Jacobson, Joan M Griffin, Paul J Limburg, Lila J Finney Rutten> ;Preventing Chronic Disease. 2022 Apr 14
7 citations
Colonoscopy Findings in FIT+ and mt-sDNA+ Patients versus in Colonoscopy-only Patients: New Hampshire Colonoscopy Registry Data.
Joseph C Anderson, Christina M Robinson, William Hisey, Paul J Limburg, Lynn F Butterly> ;Cancer Prevention Research. 2022 Jul 5
2 citations
Life-years gained resulting from screening colonoscopy compared with follow-up colonoscopy after a positive stool-based colorectal screening test.
A Mark Fendrick, Bijan J Borah, A Burak Ozbay, Leila Saoud, Paul J Limburg> ;Preventive Medicine Reports. 2022 Apr 1
7 citations
Healthcare costs of colorectal cancer screening and events following colonoscopy among commercially insured average-risk adults in the United States.
Deborah A Fisher, Nicole Princic, Lesley-Ann Miller-Wilson, Kathleen Wilson, Paul Limburg> ;Current Medical Research and Opinion. 2022 Mar 1
Multicancer early detection: International summit to Clarify the Roadmap.
Paul J Limburg, David A Ahlquist, Sonali Johnson, Shalini Jayasekar Zurn, John B Kisiel, Robert A Smith> ;Cancer. 2022 Feb 15
4 citations
Provider-perceived barriers to patient adherence to colorectal cancer screening.
Xuan Zhu, Emily Weiser, Debra J Jacobson, Joan M Griffin, Paul J Limburg, Lila J Finney Rutten> ;Preventive Medicine Reports. 2022 Feb 1
5 citations
Health Care Provider Characteristics Associated With Colorectal Cancer Screening Preferences and Use.
Lila J Finney Rutten, Philip D Parks, Emily Weiser, Chun Fan, Debra J Jacobson, Gregory D Jenkins, Xuan Zhu, Joan M Griffin, Paul J Limburg> ;Mayo Clinic Proceedings. 2022 Jan 1
12 citations
Out-of-Pocket Costs for Colonoscopy After Noninvasive Colorectal Cancer Screening Among US Adults With Commercial and Medicare Insurance.
A. Mark Fendrick, Nicole Princic, Lesley-Ann Miller-Wilson, Kathleen Wilson, Paul J. Limburg> ;JAMA Network Open. 2021 Dec 1
4 citations
Adherence to fecal immunochemical test screening among adults at average risk for colorectal cancer
Deborah A. Fisher, Nicole Princic, Lesley Ann Miller-Wilson, Kathleen Wilson, Kathryn DeYoung, A. Burak Ozbay, Paul J. Limburg> ;International Journal of Colorectal Disease. 2021 Nov 2
1 citations
Initial validation of a self-report questionnaire based on the Theoretical Domains Framework: determinants of clinician adoption of a novel colorectal cancer screening...
Xuan Zhu, Minji K. Lee, Emily Weiser, Joan M. Griffin, Paul J. Limburg, Lila J. Finney Rutten> ;Implementation Science Communications. 2021 Oct 19
6 citations
Phase I double-blind, placebo-controlled trial of dolcanatide (SP-333) 27 mg to explore colorectal bioactivity in healthy volunteers.
David S. Weinberg, Nathan R. Foster, Gary Della'Zanna, Ryan McMurray, Walter K. Kraft, Angela Pallotto, David Kastenberg, Leo Katz, Christopher H. Henry, Stephanie Mol...> ;Cancer Biology & Therapy. 2021 Oct 10
16 citations
Utilization of a Colorectal Cancer Screening Test Among Individuals With Average Risk.
Deborah A. Fisher, Nicole Princic, Lesley-Ann Miller-Wilson, Kathleen Wilson, A. Mark Fendrick, Paul J. Limburg> ;JAMA Network Open. 2021 Sep 1
14 citations
Barriers to utilization of three colorectal cancer screening options - Data from a national survey.
Xuan Zhu, Philip D. Parks, Emily Weiser, Debra J. Jacobson, Paul J. Limburg, Lila J. Finney Rutten> ;Preventive Medicine Reports. 2021 Jul 29
3 citations
Patient preferences on general health and colorectal cancer screening decision-making: Results from a national survey.
Xuan Zhu, Emily Weiser, Debra J. Jacobson, Joan M. Griffin, Paul J. Limburg, Lila J. Finney Rutten> ;Patient Education and Counseling. 2021 Jul 24
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Press Mentions

Exact Sciences Extends Leadership in Colorectal Cancer Screening with New Data Presented at Digestive Disease Week® Annual MeetingMay 9th, 2023
Exact Sciences Expands Leadership in Colorectal Cancer Screening with New Data Presented at the American College of Gastroenterology 2022 Annual MeetingOctober 24th, 2022
Exact Sciences Expands Leadership in Colorectal Cancer Screening with New Data Presented at the American College of Gastroenterology 2022 Annual MeetingOctober 23rd, 2022
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Grant Support

Molecular Epidemiology Of Colorectal Cancer SubtypesNational Cancer Institute2005–2010
Phase 1 And Phase 2 Clinical Trials Of Cancer Chemopreventive AgentsNational Cancer Institute2007
Insulin, The IGF Axis, And Colorectal NeoplasiaNational Cancer Institute2004–2005
Pre-Endoscopy Survey Of Risk Factors For GI ConditionsNational Center For Research Resources2004
Insulin, The IGF Axis, And Colorectal NeoplasiaNational Cancer Institute2001–2003