PaulSThorntonMD

PubMed

• Practice Variation among Pediatric Endocrinologists in the Dosing of Glucocorticoids in Young Children with Congenital Adrenal Hyperplasia.
  Simpson, L., Palzer, E., , Al-Rayess, H., Lahoti, A., Thornton, P., Heksch, R., Kamboj, M., Stanley, T., Regelmann, M., Gupta, A., Raman, V., Mehta, S., Geffner, M., S...> ;Children. 2023 Nov 29
• 4 citations
  New approaches to screening and management of neonatal hypoglycemia based on improved understanding of the molecular mechanism of hypoglycemia.
  Charles A Stanley, Paul S Thornton, Diva D De Leon> ;Frontiers in Pediatrics. 2023 Jan 1
• 2 citations
  Hyperinsulinemic Hypoglycemia Associated with a Ca1.2 Variant with Mixed Gain- and Loss-of-Function Effects.
  Sebastian Kummer, Susanne Rinné, Gunnar Seemann, Nadine Bachmann, Katherine Timothy, Paul S Thornton, Frank Pillekamp, Ertan Mayatepek, Carsten Bergmann, Thomas Meissn...> ;International Journal of Molecular Sciences. 2022 Jul 22
• 4 citations
  Safety and Efficacy of Lonapegsomatropin in Children With Growth Hormone Deficiency: enliGHten Trial 2-Year Results.
  Aristides K Maniatis, Samuel J Casella, Ulhas M Nadgir, Paul L Hofman, Paul Saenger, Elena D Chertock, Elena M Aghajanova, Maria Korpal-Szczyrska, Elpis Vlachopapadopo...> ;The Journal of Clinical Endocrinology and Metabolism. 2022 Jun 16
• Correction to: Congenital hyperinsulinism in infancy and childhood: challenges, unmet needs and the perspective of patients and families.
  Indraneel Banerjee, Julie Raskin, Jean-Baptiste Arnoux, Diva D De Leon, Stuart A Weinzimer, Mette Hammer, David M Kendall, Paul S Thornton> ;Orphanet Journal of Rare Diseases. 2022 May 18
• Response to Letter to the Editor From Malozowski: "Weekly Lonapegsomatropin in Treatment-Naïve Children With Growth Hormone Deficiency: The Phase 3 heiGHt Trial".
  Paul S Thornton, Aristides K Maniatis, Elena Aghajanova, Elena Chertok, Zhengning Lin, Wenjie Song, Eva Dam Christoffersen, Vibeke Miller Breinholt, Elene Giorgadze, M...> ;The Journal of Clinical Endocrinology and Metabolism. 2022 Apr 19
• 12 citations
  Congenital hyperinsulinism in infancy and childhood: challenges, unmet needs and the perspective of patients and families.
  Indraneel Banerjee, Julie Raskin, Jean-Baptiste Arnoux, Diva D De Leon, Stuart A Weinzimer, Mette Hammer, David M Kendall, Paul S Thornton> ;Orphanet Journal of Rare Diseases. 2022 Feb 19
• Response to Letter to the Editor From L. Sävendahl et al: "Weekly Lonapegsomatropin in Treatment-Naïve Children With Growth Hormone Deficiency: The Phase 3 heiGHt Trial".
  Paul S Thornton, Aristides K Maniatis, Elena Aghajanova, Elena Chertok, Elpis Vlachopapadopoulou, Zhengning Lin, Wenjie Song, Eva Dam Christoffersen, Vibeke Miller Bre...> ;The Journal of Clinical Endocrinology and Metabolism. 2022 Feb 17
• 2 citations
  Congenital Hyperinsulinism: An Historical Perspective.
  Paul S Thornton, Charles A Stanley, Diva D De Leon> ;Hormone Research in Paediatrics. 2022 Jan 1
• 6 citations
  Switching to Weekly Lonapegsomatropin from Daily Somatropin in Children with Growth Hormone Deficiency: The fliGHt Trial.
  Aristides K Maniatis, Ulhas Nadgir, Paul Saenger, Kent L Reifschneider, Jennifer Abuzzahab, Larry Deeb, Larry A Fox, Katie A Woods, Wenjie Song, Meng Mao, Steven D Che...> ;Hormone Research in Paediatrics. 2022 Jan 1
• 24 citations
  Weekly Lonapegsomatropin in Treatment-Naïve Children With Growth Hormone Deficiency: The Phase 3 heiGHt Trial.
  Paul S. Thornton, Aristides K Maniatis, Elena Aghajanova, Elena Chertok, Elpis Vlachopapadopoulou, Zhengning Lin, Wenjie Song, Eva Dam Christoffersen, Vibeke Miller Br...> ;The Journal of Clinical Endocrinology and Metabolism. 2021 Oct 21
• 3 citations
  Recent updates in the management of infants and children with hyperinsulinism.
  Paul S Thornton> ;Current Opinion in Pediatrics. 2021 May 17
• 3 citations
  What's in a name? That which we call perinatal stress hyperinsulinism by any other name would smell so bitter.
  Paul S. Thornton, Diva D De León> ;Journal of Perinatology. 2021 Apr 30
• 9 citations
  Towards enhanced understanding of idiopathic ketotic hypoglycemia: a literature review and introduction of the patient organization, Ketotic Hypoglycemia International.
  Danielle Drachmann, Erica Hoffmann, Austin Carrigg, Beccie Davis-Yates, Valerie Weaver, Paul S. Thornton, David A. Weinstein, Jacob S. Petersen, P. K. Shah, Henrik Thy...> ;Orphanet Journal of Rare Diseases. 2021 Apr 13
• 1 citations
  Brain MRIs may be of low value in most children diagnosed with isolated growth hormone deficiency.
  Jessica Schmitt, Paul Thornton, Avni Shah, A K M Falzur Rahman, Elizabeth Kubota, Patrick Rizzuto, Anshu Gupta, Sena Orsdemir, Paul B. Kaplowitz> ;Journal of Pediatric Endocrinology & Metabolism. 2021 Feb 23
• 26 citations
  Management and Appropriate Use of Diazoxide in Infants and Children with Hyperinsulinism.
  Preneet Cheema Brar, Ryan Heksch, Kristina Cossen, Diva D. De León, Manmohan K. Kamboj, Seth D. Marks, Bess A. Marshall, Ryan Miller, Laura C. Page, Takara L. Stanley,...> ;The Journal of Clinical Endocrinology and Metabolism. 2020 Dec 1
• 2 citations
  Visual interpretation, not SUV ratios, is the ideal method to interpret 18F-DOPA PET scans to aid in the cure of patients with focal congenital hyperinsulinism.
  Pradeep K. Garg, Burton Putegnat, Lisa Truong, Courtney Reynolds, Irene Sanchez, Jonathan Nedrelow, John K Uffman, Stephen J. Lokitz, Rachid Nazih, Sudha Garg, Paul S....> ;Plos One. 2020 Oct 27
• Treatment Threshold for Neonatal Hypoglycemia.
  Thornton PS, De Leon DD, Sperling MA> ;The New England journal of medicine.
• 1 citations
  The GLOW Study does not light up the true Pediatric Endocrine Society recommendations for management of hypoglycemia in newborns.
  Paul S. Thornton, Paul J. Rozance, Mark A. Sperling> ;The Journal of Pediatrics. 2020 Jun 27
• 8 citations
  PRACTICE VARIATION IN THE MANAGEMENT OF GIRLS AND BOYS WITH DELAYED PUBERTY.
  Jia Zhu, Henry A. Feldman, Erica A. Eugster, Patricia Y. Fechner, Leena Nahata, Paul S. Thornton, Yee-Ming Chan> ;Endocrine Practice. 2020 Mar 1
• 24 citations
  Current and Emerging Agents for the Treatment of Hypoglycemia in Patients with Congenital Hyperinsulinism.
  Ana Paola De Cosio, Paul Thornton> ;Paediatric Drugs. 2019 Jun 1
• 27 citations
  Rate of Serious Adverse Events Associated with Diazoxide Treatment of Patients with Hyperinsulinism.
  Paul S. Thornton, Lisa Truong, Courtney Reynolds, Tyler Hamby, Jonathan Nedrelow> ;Hormone Research in Paediatrics. 2019 Jan 1
• 4 citations
  The Incidence and Etiology of Previously Undiagnosed Hypoglycemic Disorders in the Emergency Department.
  Kathryn Jenson White, Lisa Truong, Kimberly Aaron, Nasir Mushtaq, Paul S. Thornton> ;Pediatric Emergency Care. 2018 Oct 25
• 9 citations
  Pediatric endocrine society survey of diabetes practices in the United States: What is the current state?
  Ines Guttmann-Bauman, Paul S. Thornton, S. Adhikari, K. Reifschneider, M. A. Wood, Tyler Hamby, K. Rubin> ;Pediatric Diabetes. 2018 Aug 1
• 14 citations
  Congenital hyperinsulinism as the presenting feature of Kabuki syndrome: clinical and molecular characterization of 9 affected individuals.
  Kai Lee Yap, Amy E Knight Johnson, David Fischer, Priscilla Kandikatla, Jacea Deml, Viswateja Nelakuditi, Sara Halbach, George S Jeha, Lindsay C Burrage, Olaf Bodamer,...> ;Genetics in Medicine. 2019 Jan 1
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Journal Articles

• Correction: “Congenital Hyperinsulinism as the Presenting Feature of Kabuki Syndrome: Clinical and Molecular Characterization of 10 Affected Individuals”  
  Lindsay C Burrage, Sara Halbach, Paul Thornton, Andrew C Edmondson, Alejandro Diaz, Lisa Truong, Darrel Waggoner, Nature
• Congenital Hyperinsulinism as the Presenting Feature of Kabuki Syndrome: Clinical and Molecular Characterization of 10 Affected Individuals  
  Alejandro Diaz, Darrel Waggoner, Lindsay C Burrage, Sara Halbach, Andrew C Edmondson, Lisa Truong, Paul Thornton, Nature

Books/Book Chapters

• Congenital Hyperinsulinism: Practical Guide to the Diagnosis and Management. 
  Chapter: The Diagnosis of hyperinsulinism 
  P S Thornton and CA StanleyEditors: Stanley CA and DeLeon D..
• Congenital Hyperinsulinism: Practical Guide to the Diagnosis and Management. 
  Chapter: Post-operative management of diabetes and pancreatic insufficiency. 
  Jefferson N Brownell, MD , Heather McKinght -Menci, CRNP, Asim Maqbool, MD, Paul S Thornton, MDEditors: Stanley CA and DeLeon D.
• Pediatric Endocrinology and Inborn Errors Of metabolism. 
  Chapter: Hyperinsulinism 
  Kelly A, DeLonlay P, Thornton P, Stanley CAEdition 2nd,
• Textbook of Pediatric Endocrinology 
  Chapter: Hypoglycemia in the Newborn and Infant 
  Diva De Leon, Paul S. Thornton, Charles A. Stanley, Mark A. SperlingEditors: Sperling MA. Elsevier ScienceEdition 5th,2020
• Textbook of Pediatric Endocrinology 
  Chapter: Hypoglycemia in the Newborn and Infant 
  Diva De Leon, Paul S. Thornton, Charles A. Stanley, Mark A. SperlingEditors: Sperling MA ed. Elsevier Science.Edition 4th,2014
• Fetal and Neonatal physiology 
  Chapter: Ketone Body Production and Metabolism in the Fetus and Neonate. 
  D H Williamson & Thornton PSEditors: WB Saunders.Polin, Fox and AbmanEdition 4th,2011
• Requisites in Pediatrics 
  Chapter: Hypoglycemia. 
  Thornton PS.Editors: Moshang Jr, Tom.Elsevier Mosby2005
• Fetal and Neonatal physiology 
  Chapter: Ketone Body Production and Metabolism in the Fetus and Neonate. 
  D H Williamson & Thornton PSEditors: Polin, Fox and Abman.WB SaundersEdition 3rd,2004
• Textbook of Pediatric Endocrinology 
  Chapter: Hypoglycemia in infants and neonates. 
  Stanley CA, Thornton PS, Finegold DN, Sperling MA.Editors: Sperling MA.Elsevier Science2002
• Textbook of Pediatric Endocrinology 
  Chapter: Hypoglycemia in the infant and child. 
  Thornton PS, Finegold DN, Stanley CA, Sperling MAEditors: Sperling MA.Elsevier Science2002
• The Clinical Handbook of Pediatrics 
  Chapter: Precocious Puberty in Schwartz 
  M Satin Smith and Thornton PSEditors: MW. Williams & Wilkins, Baltimore2002
• Neonatology: Pathophysiology and Management of the Newborn 
  Chapter: Endocrine disorders in the newborn. 
  Moshang T. Jr, Thornton PSEditors: Avery GB, Fletcher MA and Macdonald MG.Edition 5th,1998
• Textbook of Pediatric Critical Care 
  Chapter: Disorders of intermediary metabolism. 
  Thornton PS, Berry GT, Stanley CAEditors: Holbook PR.Philadelphia1993
• Neonatology: Pathophysiology and Management of the Newborn . 
  Chapter: Endocrine disorders in the newborn. 
  Moshang T, Jr, Thornton PSEditors: Avery GB, Fletcher MA and Macdonald MG.Edition 4th,1993
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Abstracts/Posters

• Duration of Fasting Studies Required to Demonstrate a Cure for Patients with Focal Congenital Hyperinsulinism
  Lisa Truong, Courtney Reynolds and Paul Thornton, Poster Presentation at ESPE, 9/22/2021
• Outcomes of Feeding Interventions on Patients with Genetic HI
  Courtney Reynolds, Lisa Truong, and Paul Thornton., Presentation at Congenital Hyperinsulinism Research Conference, 9/18/2021
• The Effectiveness of Low Dose Glucagon Infusion (<5 mcg/kg/hr) in Preventing Hypoglycemia.
  Courtney Reynolds, Lisa Truong, and Paul Thornton., Presentation at Congenital Hyperinsulinism Research Conference, 9/18/2021
• Lonapegsomatropin (TransCon hGH) in Children with Growth Hormone Deficiency: Efficacy and Safety of up to 2 Years of Treatment.
  Aristides K. Maniatis, Ulhas M. Nadgir, Paul Hofman, Paul Saenger, Elena D. Chertok, Elena M. Aghajanova, Wenjie Song, Meng Mao, Steven Chessler, Allison Komirenko, Mi..., Poster presented at: Pediatric Endocrine Society Annual Meeting, Virtual Annual Meeting, 4/30/2021
• Comparison of height and arm span measurements in response to long term growth hormone treatment in GH deficient meningomyelocele children.
  Satin-Smith M, Levitt-Katz L, Thornton PS, Gruccio D, Charney E, Moshang T Jr, Society for Pediatric Research, 1994.
• Growth failure is reduced in neuroblastoma patients prepared for bone marrow transplant with thiotepa
  Levit Katz LE, Bunin N, Goldwein J, Thornton PS, Alter CA, Moshang T, Jr., Society for Pediatric Research annual meeting 1993
• Growth hormone deficiency in children treated for head and neck sarcoma.
  Winyard PJ, Thornton PS, Gruccio DA, Bunin N, Moshang, T, The Endocrine Society, 1992.
• In vitro and in vivo effects of GCSF on neutrophils (PMN) in Glycogen Storage Disease 1B (GSD1B).
  Kilpatrick L, McCawley L, Korchak HM, Thornton PS, Stanley CA, Baker L, Douglas SD, Oral Presentation .Pediatric Research 31:152A, 1992
• Diagnosis of partial ACTH deficiency using IRMA ACTH in conjunction with the short metyrapone test.
  Thornton PS, Alter CA, Willi SM, Gruccio D, Moshang T, Pediatric Research 31:85A, 1992 (Poster Presentation).
• Octreotide therapy in hyperinsulinism.
  Thornton PS, Alter CA, O&#39;Neill JA, Baker L, Stanley CA, Pediatric Research 31:189A, 1992 (Oral Presentation).
• Uncooked cornflour compared to high protein diet in the treatment of GSD Type III.
  McCallion N, Irranca M, Naughten E, and Thornton PS., SSIEM 1998. J. Inher. Metab. Dis. 21: suppl 2;
• A novel molecular aetiology for congenital hyperinsulinism.
  Ryan F, Joyce C, Devany D, Costigan C, Barton D, Glaser B, and Thornton PS, SSIEM 1998. J. Inher. Metab. Dis. 21: suppl 2; 131
• Hyperinsulinism and Hyperammonemia. A distinct genetic syndrome.
  Weinzimmer SA, Yudkoff M, Thornton PS, Stanley CA., Pediatric Research 1996. 39 (4) part 2 98A
• Use of a sensitive assay to document elevated insulin levels in congenital hyperinsulinism.
  Satin-Smith M, Katz LEL, Drott H, Collett-Solberg P, Weinzimer SA, Thornton PS, Baker L, and Stanley CA., Pediatric Research 1996, 39 :(4) part 2 149A.
• Is Deficiency of Vitamin D Binding Protein Lethal in Mice?
  Thornton, PS., Monks, B.R., Liebhaber, S.A., Cooke, N.E., 77th Annual Meeting of the Endocrine Society, Washington, D.C., June 14 - 17, 1995, p. 589.
• Generation of a Mouse Line Null for Vitamin D Binding Protein by Targeted Homologous Recombination.
  Thornton, P.S., Monks, B.R., Hu, Y., Haddad, J.G., Liebhaber, S.A., Cooke, N.E., 17th Annual Meeting of the American Society of Bone and Mineral Research, Baltimore, MD, Sept. 9 - 13, 1995, J.Bone Mineral Res.10:S494, 1995.
• Genotype/Phenotype correlations in recessively inherited B-cell KATP channel mutation patients.
  MacMullen CM, Kim RJW, Thornton PS, Underwood P, Bhatia P, Steinkrauss L, Ganguly A, Stanley CA., Presentation at the Lawson Wilkins Pediatric Endocrine Society and Pediatric Academic Societies’ Annual Meetings, Pediatric Research 53 (4): 133A, 2003
• Normal ammonia levels in patients with glutamate dehydrogenase hyperinsulinism (Hyperinsulinism/Hyperammonemia Syndrome).
  Thornton PS, Kelly A, MacMullen CM, Hsu BYL, Steinkrauss L, Stanley CA, 40th International Congress of Inborn Errors of Metabolism, Dublin, Ireland, UK. September 3-6. J Inher Metab Dis, 25 (Suppl.1): 137, 2002
• Powdered Maltodextrin is More Cost Effective than IV D20% solutions in the Treatment of Congenital Hyperinsulinism.
  Lisa Truong, CPNP; Courtney Reynolds, MPH, Kathy O&#39;Bryan, MS RD LD; Erin Walkley, RD LD ; Lindsay Pyke, RD LD; Paul Thornton, MD, Poster Presentation at PES, Fort Worth ,TX, 4/24/2020
• Developmental Outcomes in Patients with Hyperinsulinism.
  Cortney Wolfe-Christensen, PhD; Courtney Reynolds, MPH; Lisa Truong, CPNP; Paul Thornton, MD, Poster Presentation at PES, Fort Worth ,TX, 4/24/2020
• The Endocrine Manifestations of Maternal UPD 14, a Prader-Willi-like Syndrome.
  Roy S.M., Thornton PS, Poster presentation to be given at the 2020 Pediatric Endocrine Society Annual Meeting,, Fort Worth, TX., 4/24/2020
• Developmental Outcomes in Patients with Hyperinsulinism.
  Cortney Wolfe-Christensen, PhD; Courtney Reynolds, MPH; Lisa Truong, CPNP; Paul Thornton, MD., Oster Presentation at PESTOLA, Little Rock Arkansas, 2/7/2020
• Powdered Maltodextrin is More Cost Effective than IV D20% solutions in the Treatment of Congenital Hyperinsulinism
  Lisa Truong, CPNP; Courtney Reynolds, MPH, Kathy O&#39;Bryan, MS RD LD; Erin Walkley, RD LD ; Lindsay Pyke, RD LD; Paul Thornton, MD, PESTOLA, Little Rock Arkansas, 2/7/2020
• Developmental Outcomes in Patients with Hyperinsulinism.
  Cortney Wolfe-Christensen, PhD; Courtney Reynolds, MPH; Lisa Truong, CPNP; Paul Thornton, MD, PESTOLA, Little Rock Arkansas, 2/7/2020
• Phase 3 fliGHt Trial: Experience of Switching from Daily Growth Hormone Therapy to Once-weekly TransCon hGH in Children with Growth Hormone Deficiency.
  Maniatis AK, Nadgir U, Saenger P, Mick G, Reifschneider KL, Abuzzahab MJ, Deeb L, 26 Fox LA, Woods KA, Peng JM, Karpf DB, Shu AD, Song W, Casella SJ, and Thornton PS., ENDO, 2020
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Lectures

• Novel use of a pump post pancreatectomy for congenital hyperinsulinism. 
  The 47th annual conference of the International Society for Pediatric and Adolescent Diabetes - 10/2021
• Mapping the source of HI. 
  National Association of Neonatal Nurses 37th Annual Conference. - 9/2021
• Controversies in Neonatal Hypoglycemia. 
  The 2021 annual meeting of the British Society of Pediatric Endocrinology and Diabetes - 9/2021
• Clinical approach to the management of congenital hyperinsulinism. 
  15th Annual Canadian Pediatric Endocrine Group (Virtual) - 2/2021
• Neonatal Hypoglycemia: a 2021 update. 
  Grand rounds. UT Health Houston, Tx - 1/2021
• Neonatal Hypoglycemia: a 2021 update. 
  Pediatric Grand rounds. Cook Children’s Medical Center, Fort Worth ,Tx - 1/2021
• Practical Management of Hyperinsulinism. 
  UCLA ,Ca. - 1/2021
• Update on congenital Hyperinsulinism 
  Pediatric Grands Rounds Banner University Medical Center Tuscan Arizona - 12/2020
• Ken Copeland Visiting Professor Award: "Hypoglycemia in infancy: update" 
  Pediatric Grand Rounds Oklahoma University Medical Center - 11/2020
• Brain damage and Hypoglycemia. 
  Neonatology Ground Rounds Oklahoma University Medical Center - 11/2020
• Hypoglycemia in the older infants and children 
  PICU/ER Physicians Rounds Oklahoma University Medical Center - 11/2020
• Update on congenital Hyperinsulinism. 
  Children’s Hospital Los Angeles - 11/2020
• Guided Posters: Pediatric Endocrinology 
  ENDO 2019 - New Orleans, LA - 3/23/2019
• General Pediatric Endocrinology, T1D, Hypoglycemia, and Growth 
  ENDO 2019 - New Orleans, LA - 3/23/2019
• Pediatric Type 1 Diabetes, Adrenal, Puberty, Bone, and Growth 
  ENDO 2019 - New Orleans, LA - 3/24/2019
• Congenital Hyperinsulinism 
  Kuwait - 11/2018
• Hyperinsulinism workshop Endocrine division 
  La Bonheur Children’s Hospital, Memphis Tennessee. - 10/2018
• Update on Hypoglycemia Ground Rounds 
  Le Bonheur Children’s Hospital in Memphis, TN - 10/2018
• Guidelines for Diagnosing and Treating Hypoglycemia in Infants CHI Family Conference, 
  Athens, Greece - 9/2018
• Multiple talks and workshops at the Congenital Hyperinsulinism International Family Conference, 
  Fort Worth TX - 7/2018
• PES Hypoglycemia Guidelines.5th Sandoz EDGE Conference 
  Brazil - 6/2018
• Update on PES hypoglycemia Guidelines. 6th Annual international Hospital Espanola Conference 
  Mexico City, MX - 5/2018
• In office Retinal scanner improves compliance in annual retinal screening in diabetes 
  Pediatric Endocrine Society of Texas, Oklahoma, Louisiana, and Arkansas in New Orleans, LA - 2/2018
• Update on Congenital Hyperinsulinism and Adrenal Disorders 
  North Western Ped Endo Society (PEARL) Tacoma Washington State. - 3/2017
• Hypoglycemia 
  TPA Conference. San Angelo, TX - 9/2016
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Other

• Hypoparathyroidism 
  Kelly, A., P.S. Thornton
  Emedicine - 2000
• Fatty acid oxidation disorders. 
  Thornton, PS.
  Yourdoctor.Com - 2000
• Hyperinsulinism 
  A. Kelly and P. S. Thornton.
  Yourdoctor.Com - 2000