PaulWWongMD

PubMed

• 68 citations
  Discovery of betrixaban (PRT054021), N -(5-chloropyridin-2-yl)-2-(4-( N , N -dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orall...
  Penglie Zhang, Wenrong Huang, Lingyan Wang, Bao Liang, Zhaozhong J. Jia, Bauer Shawn M, Erick A. Goldman, Gary Probst, Yonghong Song, Ting Su, Jingmei Fan, Yanhong Wu,...> ;Bioorganic & Medicinal Chemistry Letters. 2009 Apr 15
• 7 citations
  Anthranilamide-based N,N-dialkylbenzamidines as potent and orally bioavailable factor Xa inhibitors: P4 SAR.
  Penglie Zhang, Bao Liang, Jingmei Fan, Zhaozhong J. Jia, Uma Sinha, Paul W. Wong, Gary Park, Athiwat Hutchaleelaha, Robert M. Scarborough, Bing-Yan Zhu> ;Bioorganic & Medicinal Chemistry Letters. 2009 Apr 15
• A study of sexual satisfaction and frequency of sex among Hong Kong Chinese couples.
  Cheung, M.W., Wong, P.W., Liu, K.Y., Yip, P.S., Fan, S.Y., Lam, T.> ;J Sex Res. 2008-04-01
• 48 citations
  Synergistic induction of tissue factor by coagulation factor Xa and TNF: Evidence for involvement of negative regulatory signaling cascades
  Ayala Hezi-Yamit, Paul W. Wong, Nga Bien-Ly, László G. Kömüves, K. S. Srinivasa Prasad, David Phillips, Uma Sinha> ;Proceedings of the National Academy of Sciences of the United States of America. 2005 Aug 23
• 8 citations
  Parallel synthesis and structure-activity relationships of a series of highly potent, selective, and neutral factor Xa inhibitors.
  Bauer Shawn M, Erick A. Goldman, Wenrong Huang, Ting Su, Lingyan Wang, John Woolfrey, Yanhong Wu, Jingmei Zuckett, Ann E. Arfsten, Brian Huang, Jaya Kothule, Joyce Lin...> ;Bioorganic & Medicinal Chemistry Letters. 2004 Aug 2
• Atrophic macular degeneration mutations in ELOVL4 result in the intracellular misrouting of the protein.
  Ambasudhan, R., Wang, X., Jablonski, M.M., Thompson, D.A., Lagali, P.S., Wong, P.W., Sieving, P.A., Ayyagari, R.> ;Genomics. 2004 Apr
• Characterization of mouse orthologue of ELOVL4: genomic organization and spatial and temporal expression.
  Mandal, M.A., Ambasudhan, R., Wong, P.W., Gage, P.J., Sieving, P.A., Ayyagari, R.> ;Genomics. 2004 Apr
• Evolutionarily conserved ELOVL4 gene expression in the vertebrate retina.
  Lagali, P.S., Liu, J., Ambasudhan, R., Kakuk, L.E., Bernstein, S.L., Seigel, G.M., Wong, P.W., Ayyagari, R.> ;Invest Ophthalmol Vis Sci. 2003 Jul
• 15 citations
  Inhibition of Purified Factor Xa Amidolytic Activity May Not Be Predictive of Inhibition of In Vivo Thrombosis. Implications for Identification of Therapeutically Acti...
  Uma Sinha, Pei Hua Lin, Susan Edwards, Paul W. Wong, Bing-Yan Zhu, Robert M. Scarborough, Ting Su, Zhaozhong J. Jia, Yonghong Song, Penglie Zhang, Lane A. Clizbe, Gary...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2003 Jun 1
• An integrated genetic approach to identify candidate genes for human chromosome 6q-linked retinal disorders.
  Lagali, P.S., Ayyagari, R., Wong, P.W.> ;Adv Exp Med Biol. 2003
• 17 citations
  Infantile cystinosis presenting as chronic constipation
  Farahnak Assadi, Richard H. Sandler, Paul W.K. Wong, May Salem, Lori Simenauer> ;American Journal of Kidney Diseases. 2002 Jun 1
• 37 citations
  Antithrombotic and hemostatic capacity of factor Xa versus thrombin inhibitors in models of venous and arteriovenous thrombosis.
  Uma Sinha, Paul Ku, John Malinowski, Bing Yan Zhu, Robert M. Scarborough, Charles K. Marlowe, Paul W. Wong, Pei Hua Lin, Stanley J. Hollenbach> ;European Journal of Pharmacology. 2000 Apr 21
• 22 citations
  Inhibition of factor Xa by a peptidyl-alpha-ketothiazole involves two steps. Evidence for a stabilizing conformational change.
  Andreas Betz, Paul W. Wong, Uma Sinha> ;Biochemistry. 1999 Nov 2
• 69 citations
  Genetic and nongenetic factors for moderate hyperhomocyst(e)inemia.
  Soo-Sang Kang, Paul W.K. Wong> ;Atherosclerosis. 1996 Jan 26
• 186 citations
  Thermolabile defect of methylenetetrahydrofolate reductase in coronary artery disease.
  Soo-Sang Kang, E. L. Passen, Neal Ruggie, Paul W.K. Wong, H. Sora> ;Circulation. 1993 Oct 1
• 539 citations
  Hyperhomocyst(e)inemia as a Risk Factor for Occlusive Vascular Disease
  Soo-Sang Kang, Paul W.K. Wong, M. R. Malinow> ;Annual Review of Nutrition. 1992 Jan 1
• 471 citations
  Thermolabile methylenetetrahydrofolate reductase: an inherited risk factor for coronary artery disease.
  Soo-Sang Kang, Paul W.K. Wong, A. Susmano, J. Sora, Marija Norusis, Neal Ruggie> ;American Journal of Human Genetics. 1991 Mar 1
• 12 citations
  Purification and characterization of methylenetetrahydrofolate reductase from human cadaver liver.
  Jiemin Zhou, Soo-Sang Kang, Paul W.K. Wong, Beatrice Fournier, Rima Rozen> ;Biochemical Medicine and Metabolic Biology. 1990 Jun 1
• Quinolone-resistant Neisseria gonorrhoeae in Hong Kong.
  Kam, K. M., Wong, P. W., Cheung, M. M., Ho, N. K., Lo, K. K.> ;Sex Transm Dis. 1996 Mar 01
• Recent advances in the genetics of macular dystrophies.
  Mah, D. Y., Wong, P. W., Edwards, A., MacDonald, I. M.> ;Can J Ophthalmol. 1998 Apr
• MultiPriDe: automated batch development of quantitative real-time PCR primers.
  Ziesel, A. C., Chrenek, M. A., Wong, P. W.> ;Nucleic Acids Res. 2008 May
• Intermediate hyperhomocysteinemia resulting from compound heterozygosity of methylenetetrahydrofolate reductase mutations.
  Kang, S. S., Wong, P. W., Bock, H. G., Horwitz, A., Grix, A.> ;Am J Hum Genet. 1991 Mar
• What can we do to help and understand survivors of suicide in Hong Kong?
  Wong, P. W., Chan, W. S., Beh, P. S.> ;Crisis. 2007
• Restricting the means of suicide by charcoal burning.
  Yip, P. S., Law, C. K., Fu, K. W., Law, Y. W., Wong, P. W., Xu, Y.> ;Br J Psychiatry. 2010 Mar
• Research participation experiences of informants of suicide and control cases: taken from a case-control psychological autopsy study of people who died by suicide.
  Wong, P. W., Chan, W. S., Beh, P. S., Yau, F. W., Yip, P. S., Hawton, K.> ;Crisis. 2010
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