PhilipAlanVerhoefMDPhD

Medicine/Pediatrics • Honolulu, HI

Adult and Pediatric Intensivist Kaiser Permanente Hawaii

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Office
2828 Pa'a St
Residency Program Office Room 3D04
Honolulu, HI 96822
Phone+1 808-432-7990
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Summary

Dr. Philip Verhoef is an internist and pediatrician in Honolulu, HI and is affiliated with Kaiser Permanente Medical Center. He received his medical degree from Case Western Reserve University School of Medicine and has been in practice 12 years. He also speaks multiple languages, including Thai, Spanish, and French. He is experienced in critical care medicine and internal medicine.

Education & Training

University of Chicago Medical CenterCritical Care Medicine, 2009 - 2014
University of ChicagoFellowship, Pediatric Critical Care Medicine, 2009 - 2014
UCLA David Geffen School of Medicine/UCLA Medical CenterResidency, Internal Medicine/Pediatrics, 2005 - 2009
Case Western Reserve University School of MedicineClass of 2005
Case Western Reserve UniversityPhD, Pharmacology, 2004
College of WoosterBA, Chemistry, Biology, with Honors, 1997

Certifications & Licensure

CA State Medical License 2007 - Present
HI State Medical License 2019 - 2026
IL State Medical License 2009 - 2020
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Critical Care Medicine
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Critical Care Medicine

Awards, Honors, & Recognition

Fellow of the Year for Outstanding Commitment to Resident Education University of Chicago, 2010
Noether Memorial Fund Award Recipient for Excellence in Therapeutics Case Western Reserve University, 2005
Minerva and Carl Wiggers Prize in Physiology to an Outstanding Medical Graduate Case Western Reserve University, 2005
Department of Pharmacology Graduate Student of the Year Case Western Reserve University, 2003
Luce Scholar The Henry Luce Foundation, 1999
Dean’s List College of Wooster
Phi Beta Kappa College of Wooster
Sigma Xi College of Wooster
R.E. Wilson Endowed Scholarship for Chemistry College of Wooster
J.G. Weeks Endowed Scholarship College of Wooster
Chemistry Pre-Medical Award College of Wooster
Dow Chemical Book Award College of Wooster
National Presbyterian Church Scholarship College of Wooster
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Publications & Presentations

PubMed

S1PR2: A Fulcrum in the Balance of Type 1 and Type 2 Responses during Sepsis-induced Acute Lung Injury.
Philip A Verhoef> ;American Journal of Respiratory Cell and Molecular Biology. 2024 Mar 1
3 citations
Analysis of Protein Biomarkers From Hospitalized COVID-19 Patients Reveals Severity-Specific Signatures and Two Distinct Latent Profiles With Differential Responses to...
Philip A Verhoef, Alexandra B Spicer, Carlos Lopez-Espina, Akhil Bhargava, Lee Schmalz, Matthew D Sims, Ashok V Palagiri, Karthik V Iyer, Matthew J Crisp, Alexandra Ha...> ;Critical Care Medicine. 2023 Dec 1
Using Trajectories of Bedside Vital Signs to Identify COVID-19 Subphenotypes.
Sivasubramanium V Bhavani, Chad Robichaux, Philip A Verhoef, Matthew M Churpek, Craig M Coopersmith> ;Chest. 2024 Mar 1
Identification of Clinically Significant Cytokine Signature Clusters in Patients With Septic Shock.
Jack O Zhao, Bhakti K Patel, Paulette Krishack, Matthew R Stutz, Steven D Pearson, Julie Lin, Paola A Lecompte-Osorio, Karen C Dugan, Seoyoen Kim, Nicole Gras, Anne Po...> ;Critical Care Medicine. 2023 Dec 1
2 citations
Comparison of time series clustering methods for identifying novel subphenotypes of patients with infection.
Sivasubramanium V Bhavani, Li Xiong, Abish Pius, Matthew Semler, Edward T Qian, Philip A Verhoef, Chad Robichaux, Craig M Coopersmith, Matthew M Churpek> ;Journal of the American Medical Informatics Association. 2023 May 19
25 citations
Development and validation of novel sepsis subphenotypes using trajectories of vital signs.
Sivasubramanium V Bhavani, Matthew Semler, Edward T Qian, Philip A Verhoef, Chad Robichaux, Matthew M Churpek, Craig M Coopersmith> ;Intensive Care Medicine. 2022 Nov 1
1 citations
Association Between Critical Events in the PICU and Outcomes in Neighboring Patients.
Ahmed Arshad, Catherine Blandon, Kyle Carey, Philip Verhoef, Priti Jani, Samuel Volchenboum, Matthew Churpek, Anoop Mayampurath> ;Critical Care Explorations. 2022 Oct 1
12 citations
Racial Differences in Detection of Fever Using Temporal vs Oral Temperature Measurements in Hospitalized Patients.
Sivasubramanium V Bhavani, Zanthia Wiley, Philip A Verhoef, Craig M Coopersmith, Ighovwerha Ofotokun> ;JAMA. 2022 Sep 6
Chronic Lymphocytic Leukemia With Leptomeningeal Involvement Presenting as an Acute Encephalopathy.
William H Bae, Matthew Yee, Leina'ala Song, Monique M Canonico, Philip A Verhoef, Kelly A Shimabukuro> ;The Permanente Journal. 2022 Jun 29
5 citations
Coronavirus Disease 2019 Temperature Trajectories Correlate With Hyperinflammatory and Hypercoagulable Subphenotypes.
Sivasubramanium V Bhavani, Philip A Verhoef, Cheryl L Maier, Chad Robichaux, William F Parker, Andre Holder, Rishikesan Kamaleswaran, May D Wang, Matthew M Churpek, Cr...> ;Critical Care Medicine. 2022 Feb 1
16 citations
Severe Acute Respiratory Syndrome-Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research.
Philip A. Verhoef, Sujatha Kannan, Jamie Sturgill, Elizabeth W. Tucker, Peter E. Morris, Andrew Miller, Travis R. Sexton, Jay L. Koyner, Rana Hejal, Scott C. Brakenrid...> ;Critical Care Explorations. 2021 Mar 12
16 citations
IL-33-mediated Eosinophilia Protects against Acute Lung Injury.
Paulette A. Krishack, Maile K. Hollinger, Timothy G. Kuzel, Trevor S. Decker, Tyler J. Louviere, Cara L. Hrusch, Anne I. Sperling, Philip A. Verhoef> ;American Journal of Respiratory Cell and Molecular Biology. 2021 Apr 30
27 citations
Temperature Trajectory Subphenotypes Correlate With Immune Responses in Patients With Sepsis.
Sivasubramanium V. Bhavani, K. S. Wolfe, Cara L. Hrusch, Jared A. Greenberg, Paulette A. Krishack, Julie Lin, P. Lecompte-Osorio, Kyle A Carey, John P. Kress, Craig M....> ;Critical Care Medicine. 2020 Nov 1
16 citations
Novel Temperature Trajectory Subphenotypes in COVID-19.
Sivasubramanium V. Bhavani, Elbert S. Huang, Philip A. Verhoef, Matthew M. Churpek> ;Chest. 2020 Jul 21
33 citations
Caring for Critically Ill Adults With Coronavirus Disease 2019 in a PICU: Recommendations by Dual Trained Intensivists.
Kenneth E. Remy, Philip A. Verhoef, Jay R. Malone, Michael Ruppe, Timothy B. Kaselitz, Frank Lodeserto, Eliotte L. Hirshberg, Anthony D. Slonim, Cameron Dezfulian> ;Pediatric Critical Care Medicine. 2020 Jul 1
24 citations
Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes.
M. Fatih Abasıyanık, K. S. Wolfe, Hoang Van Phan, Jing Lin, Bharathi Laxman, Steven R. White, Philip A. Verhoef, Gökhan M. Mutlu, Bhakti K. Patel, Savaş Tay> ;Nature Communications. 2020 May 25
28 citations
High-flow nasal cannula may be no safer than non-invasive positive pressure ventilation for COVID-19 patients.
Kenneth E. Remy, John C. Lin, Philip A. Verhoef> ;Critical Care. 2020 Apr 23
5 citations
POINT: Should Pulmonary/ICU Physicians Support Single-payer Health-care Reform? Yes
Adam Gaffney, Philip A. Verhoef, Jesse B. Hall> ;Chest. 2016 Jul 1
Meeting Meaningful Use Criteria and Managing Patient Populations
Philip A. Verhoef> ;Annals of Internal Medicine. 2013 Nov 19
Reply to Maitra and Bhattacharjee: Adherence to the Prevailing Sepsis Definition Is Quintessential to Subphenotype Identification.
Sivasubramanium V. Bhavani, Philip A. Verhoef, Matthew M. Churpek> ;American Journal of Respiratory and Critical Care Medicine. 2020 Jan 15
5 citations
Allergic Immune Diseases and the Risk of Mortality Among Patients Hospitalized for Acute Infection.
Philip A. Verhoef, Sivasubramanium V. Bhavani, Kyle A Carey, Matthew M. Churpek> ;Critical Care Medicine. 2019 Dec 1
87 citations
Identifying Novel Sepsis Subphenotypes Using Temperature Trajectories.
Sivasubramanium V. Bhavani, Kyle A Carey, Emily R. Gilbert, Majid Afshar, Philip A. Verhoef, Matthew M. Churpek> ;American Journal of Respiratory and Critical Care Medicine. 2019 Aug 1
Reply to Leijte et al.: Fever in Sepsis: Still a Hot Topic.
Sivasubramanium V. Bhavani, Philip A. Verhoef, Matthew M. Churpek> ;American Journal of Respiratory and Critical Care Medicine. 2019 Jul 15
36 citations
Protection against Staphylococcus aureus bacteremia-induced mortality depends on ILC2s and eosinophils.
Paulette A. Krishack, Tyler J. Louviere, Trevor S. Decker, Timothy G. Kuzel, Jared A. Greenberg, Daniel F. Camacho, Cara L. Hrusch, Anne I. Sperling, Philip A. Verhoef> ;JCI Insight. 2019 Mar 21
1 citations
When It Comes to Alternaria, Instant CARMA's Gonna Get You
Philip A. Verhoef, Jennifer L. Ingram> ;American Journal of Respiratory Cell and Molecular Biology. 2018 Nov 30
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Journal Articles

Recommended Reading from the University of Chicago Pulmonary and Critical Care Fellows, John F. McConville, Program Director
Patterson, K, P.J. McShane, M.M. Churpek, and P.A. Verhoef, Am J Respir Crit Care Med, 1/1/2010

Abstracts/Posters

Bronchoscopic Lung Volume Reduction of Hyper-Expanded Native Lung in a Single Lung Transplant Recipient
Georgitis E.S., P.A. Verhoef, E Garrity, and D.K. Hogarth, 2011 American Thoracic Society Meeting, 1/1/2011
The Effect of Endobronchial Valves (EBV) for the Treatment of Persistent Airleaks in Medical Intensive Care Unit Patients
Mahajan, A. P.A. Verhoef, G. Carr, and D.K. Hogarth, Department of Internal Medicine Research Day, University of Chicago, 2/1/2010
Bronchoscopic Closure of a Bronchopleural Fistula Associated with RadioFrequency Ablation Using Intra-Bronchial Valves
Verhoef, P.A, D.K. Hogarth, 2010 American Thoracic Society Meeting, New Orleans, LA, 1/1/2010
Comparison and Evaluation of the Management of Sepsis in the PICU and MICU
Verhoef, P.A., S. Rivera, 2009 Solomon Scholars Research Day, UCLA Department of Internal Medicine, 1/1/2009
International Pediatric Global Health Elective in Ghana
Verhoef, P.A., A. Rampal, D. Rickard, R. Dudovitz, and A. Kuo, 2008 American Academy of Pediatrics National Conference and Exhibition, Boston, MA, Section on Inter, 1/1/2008
Maitotoxin-induced IL-1 beta Release and Membrane Blebbing in Murine Macrophages
Verhoef, P.A., M. A. Estacion, W. P. Schilling, S. B. Kertesy and G. R. Dubyak, The FASEB Journal, 2004 Experimental Biology Meeting Abstracts, Experimental Biology 2004, 1/1/2004
LPS Induction of Caspase-12 Processing in Murine Macrophages
Verhoef, P.A., and G. R. Dubyak, The FASEB Journal, 2003 Experimental Biology Meeting Abstracts, Experimental Biology 2003, 1/1/2003
P2X7-Dependent Membrane Blebbing in Macrophages: ROCK-Dependent, Caspase-Independent
Verhoef, P.A., M. Estacion, W. Schilling, and G.R. Dubyak, Third International Workshop on Ecto-ATPases, 1/1/2002
The half-calmodulin gene: A study of the minimal structural requirements for calmodulin in vivo function in Paramecium tetraurelia
Hendel, E., P. Verhoef,., R. D. Hinrichsen, and D. Fraga, Ohio J. Science, 1/1/1999
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Authored Content

Coronavirus Frightens MeMarch 2020
Surprise Medical Bills, Coronavirus, and Bad InsuranceMarch 2020

Press Mentions

Key Medical Devices Are Failing to Diagnose Black Patients Accurately, Research ShowsNovember 30th, 2022
PNHP Newsletter: Fall 2021July 16th, 2021
500,000 Americans Will Go Bankrupt This Year from Medical Bills?January 14th, 2020
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